Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice
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Author：
Lu Hanlin, Yuan Peidong, Ma Xiaoping, Jiang Xiuxin, Liu Shaozhuang, Ma Chang, Philipsen Sjaak, Zhang Qunye, Yang Jianmin, Xu Feng, Zhang Cheng, Zhang Yun, Zhang Wencheng
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Nature Communications
Insights into the Ancient Adaptation to Intertidal Environments by Red Algae Based on a Genomic and Multiomics Investigation of Neoporphyra haitanensis
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Author：
Chen Haimin, Chu Jeffrey Shih-Chieh, Chen Juanjuan, Luo Qijun, Wang Huan, Lu Rui, Zhu Zhujun, Yuan Gaigai, Yi Xinxin, Mao Youzhi, Lu Caiping, Wang Zekai, Gu Denghui, Jin Zhen, Zhang Caixia, Weng Ziyu, Li Shuang, Yan Xiaojun, Yang Rui
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MOLECULAR BIOLOGY AND EVOLUTION
The endothelium permeability after bioresorbable scaffolds implantation caused by the heterogeneous expression of tight junction proteins
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Junyang Huang, Shuang Ge, Desha Luo, Ruolin Du, Yang Wang, Wanling Liu, Guixue Wang, Tieying Yin
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Materials Today Bio
Myocardium-Targeted Micelle Nanomedicine That Salvages the Heart from Ischemia/Reperfusion Injury
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Author：
Liqiang Yang, Juanjuan Peng, Aiping Shi, Xueshen Wang, Junyao Li, Yaoquan Su, Kunpeng Yin, Lingzhi Zhao, Yanli Zhao
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ACS Applied Materials & Interfaces
Gastric cancer cell-derived extracellular vesicles disrupt endothelial integrity and promote metastasis
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Author：
Min Wang, Wei Cai, Ai-Jun Yang, Chen-Yu Wang, Chen-Li Zhang, Wei Liu, Xiao-Feng Xie, Yuan-Yuan Gong, Ying-Ying Zhao, Wen-Cheng Wu, Quan Zhou, Chan-Yuan Zhao, Jing-Fei Dong, Min Li
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CANCER LETTERS
Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis
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Author：
Tingyan Liu, Caiyan Zhang, Jiayun Ying, Yaodong Wang, Gangfeng Yan, Yufeng Zhou, Guoping Lu
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Frontiers in Immunology
Hyperoside mitigates photoreceptor degeneration in part by targeting cGAS and suppressing DNA-induced microglial activation
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Author：
Li Daijin, Chang Jie, Wang Yujue, Du Xiaoye, Xu Jing, Cui Jingang, Zhang Teng, Chen Yu
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Acta Neuropathologica Communications
Lidocaine pretreatment attenuates inflammatory response and protects against sepsis-induced acute lung injury via inhibiting potassium efflux-dependent NLRP3 activation
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Author：
Su Kai, Li Xin-Tao, Hong Fang-Xiao, Jin Mu, Xue Fu-Shan
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INFLAMMATION RESEARCH
Nerve growth factor alleviates arsenic-induced testicular injury by enhancing the function of Sertoli cells
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Author：
Yanping Yang, Yan Hong, Jing Han, Zhe Yang, Nanmin Huang, Binwei Xu, Zhaolei Ma, Qi Wang
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation
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Author：
Peng Junnan, Tang Rui, He Jing, Yu Qian, Wang Daoxin, Qi Di
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Journal of Translational Medicine
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein
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Author：
Lifan He, Hanlin Lu, Xuyang Ji, Jianying Chu, Xiaoteng Qin, Min Chen, Lee S. Weinstein, Jiangang Gao, Jianmin Yang, Qunye Zhang, Cheng Zhang, Wencheng Zhang
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Frontiers in Pharmacology
CMTM3 regulates vascular endothelial cell dysfunction by influencing pulmonary vascular endothelial permeability and inflammation in ARDS
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Author：
Ziyan Xiao, Gang Zhou, Haiyan Xue, Lihe Chen, Xiujuan Zhao, Shu Li, Chun Fu, Zhengzhou Wang, Fengxue Zhu
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Frontiers in Immunology
Long Non-Coding RNA-Cardiac-Inducing RNA 6 Mediates Repair of Infarcted Hearts by Inducing Mesenchymal Stem Cell Differentiation into Cardiogenic Cells through Cyclin-Dependent Kinase 1
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Author：
Xiaotian Cui, Hui Dong, Shenghe Luo, Bingqi Zhuang, Yansheng Li, Chongning Zhong, Yuting Ma, Lan Hong
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
TFAM-Mediated mitochondrial transfer of MSCs improved the permeability barrier in sepsis-associated acute lung injury
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Zhang Feng, Zheng Xinglong, Zhao Fengzhi, Li Longzhu, Ren Yinlong, Li Lijun, Huang Haiyan, Yin Haiyan
Integrated serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of yiqitongmai decoction (YQTMD) against myocardial infarction
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Author：
Hao Yu, Ning Wang, Xuerong Zhao, Lan Han, Jinyong Peng
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JOURNAL OF ETHNOPHARMACOLOGY
Hyperglycemia-induced oxidative stress exacerbates mitochondrial apoptosis damage to cochlear stria vascularis pericytes via the ROS-mediated Bcl-2/CytC/AIF pathway
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Tian-feng Shi, Zan Zhou, Wen-jun Jiang, Tian-lan Huang, Jun-qiang Si, Li Li
Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling
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Qin Xinghua, Liu Binghua, Gao Feng, Hu Yuanyuan, Chen Ziwei, Xu Jie, Zhang Xing
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Frontiers in Physiology
Exploring the Mechanism of Salvianolic Acid B against Myocardial Ischemia-Reperfusion Injury Based on Network Pharmacology
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Qianping Mao, Chongyu Shao, Huifen Zhou, Li Yu, Yida Bao, Yali Zhao, Jiehong Yang, Haitong Wan
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Pharmaceuticals
Transplantation of Neural Stem Cells-Overexpressed Ku70 Improves Neurological Deficits in a Mice Model of Cerebral Ischemia Stroke
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Liu Hui, Jiang Chonghua, Peng Jun, Hu Xiqi, Xia Ying
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NEUROCHEMICAL RESEARCH
The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway
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Author：
Dong Xiao-Liu, Wang Yan-Hui, Xu Jing, Zhang Nan
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Scientific Reports
Comparative transcriptomic and metabolic profiling provides insight into the mechanism by which the autophagy inhibitor 3-MA enhances salt stress sensitivity in wheat seedlings
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Yue Jieyu, Wang Yingjie, Jiao Jinlan, Wang Huazhong
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BMC PLANT BIOLOGY
Overexpression of Plakophilin2 Mitigates Capillary Leak Syndrome in Severe Acute Pancreatitis by Activating the p38/MAPK Signaling Pathway
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Author：
Hui Liu, Xuan Xu, Ji Li, Zheyu Liu, Yuwen Xiong, Mengli Yue, Pi Liu
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Journal of Inflammation Research
Geniposidic acid protects lipopolysaccharide-induced acute lung injury via the TLR4/MyD88 signaling pathway in vitro and in vivo
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IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
Propofol protects cardiomyocytes from hypoxia/reoxygenation injury via regulating MALAT1/miR-206/ATG3 axis
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Author：
Haijuan Jing, Chuan Wang, Liang Zhao, Jing Cheng, Pengyu Qin, Hongqi Lin
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JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity
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Lingyan Jin, Feng Gao, Tiannan Jiang, Binghua Liu, Caiyao Li, Xinghua Qin, Qiangsun Zheng
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2
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Author：
Wei Zhao, Youyang Wu, Fanhao Ye, Shiwei Huang, Hao Chen, Rui Zhou, Wenbing Jiang
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Biomed Research International
CD137 Signal Mediates Cardiac Ischemia–Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes
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Author：
Xu Yao, Chen Rui, Yan Jinchuan, Zang Guangyao, Shao Chen, Wang Zhongqun
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Journal of Cardiovascular Translational Research
PGC-1汐 affects cochlear pericytes migration in noise-exposed mice
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Author：
Wen-jun Jiang, Zan Zhou, Yan-ping Wang, Wa Gao, Li Li, Jun-qiang Si
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
MicroRNA-155 Inhibition Activates Wnt/β-catenin Signaling to Restore Th17/Treg Balance and Protect against Acute Ischemic Stroke
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Wenli Huang, Quanlong Hong, Huimin Wang, Zhihua Zhu, Shujie Gong
Catheterization of Ventral Caudal Artery in Rats: A Modified Technique for Repeatable Angiography and Intervention
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Author：
Qun Gao, Jingwen Fan, Shen Hu, Daming Wang
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JOURNAL OF INVESTIGATIVE SURGERY
Protective Effect of Isothiazolinone Derivative on Acute Lung Injury by Regulating PI3K-AKT Signaling Pathway
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Hua Li, Jie Guo, Gaiyue Zhang, Jing Zhou, Qiang Wang
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CHEMISTRY & BIODIVERSITY
Establishment and Evaluation of a Novel High-Efficiency Model of Graded Traumatic Brain Injury in Mice
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Author：
Bing Chen, Quan-xing Shi, Chuang Nie, Zhi-ping Zhao, Ling Luo, Quan-jun Zhao, Shao-yan Si, Bing-xin Xu, Tao Wang, Ling-yu Gao, Jian-wen Gu
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World Neurosurgery
Ophiopogonin D Alleviates Sepsis-Induced Acute Lung Injury Through Improving Microvascular Endothelial Barrier Dysfunction via Inhibition of HIF-1α-VEGF Pathway
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Author：
Fang Yi, Qiu Jun, Xu Yu, Wu Qing, Huo Xing-chen, Liu Song-hua
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CELL BIOCHEMISTRY AND BIOPHYSICS
Febuxostat, a xanthine oxidase inhibitor, regulated long noncoding RNAs and protected the brain after intracerebral hemorrhage
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Zhang Chenyu, Tang Linqiao, Zhang Ying, Wang Qi, Wang Xueyan, Bai Yang, Fang Zhenwei, Zhang Tiejun, Xu Ting, Li Yuwen
Overexpression of Circ_0005585 Alleviates Cerebral Ischemia Reperfusion Injury via Targeting MiR-16-5p
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Zhuang Y., Fan W. P., Yan H. S.
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BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
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您好，请问该产品的伊文斯蓝含量是多少？如何绘制该产品的标准曲线？2025-01-06 21:23:18
您好，该产品依文思蓝浓度为0.5%，标准曲线的绘制可以使用生理盐水先将0.5%依文思蓝稀释成1mg/ml，然后再依次稀释成0.2mg/ml、0.1mg/ml、0.05mg/ml、0.02mg/ml、0.01mg/ml、0.005mg/ml，测量620nm下OD值，然后以依文思蓝浓度为横坐标，OD值为纵坐标，从而绘制标准曲线。
你好，制作标曲选取什么浓度啊，以及用无水乙醇稀释好浓度后需要恒温孵育吗（如果需要的话，多少度孵育多少时间啊）2024-09-17 09:46:08
您好，标准曲线的绘制可以使用生理盐水先将0.5%依文思蓝稀释成1mg/ml，然后再依次稀释成0.2mg/ml、0.1mg/ml、0.05mg/ml、0.02mg/ml、0.01mg/ml、0.005mg/ml，测量620nm下OD值，然后以依文思蓝浓度为横坐标，OD值为纵坐标，从而绘制标准曲线。无水乙醇稀释后不需要孵育。
您好，用于肺部的伊文思蓝染色，后续检测也是用三氯乙酸吗？也按照说明书中推荐的1.5ml肺组织 1mlPBS稀释的50%的三氯乙酸的比例进行匀浆吗?2024-01-27 12:14:44
您好，脑组织主要用于血脑屏障损伤检测，如果肺部是用于肺血栓检测，匀浆及加有机溶剂离心主要为定量估算组织中伊文思蓝含量，如用于栓塞或梗死面积检查亦可适当固定后切片拍照计算着色面积。
您好，请问如何绘制该产品的标准曲线?2023-08-03 23:08:32
您好，建议用无水乙醇稀释染色液到适当浓度，然后扫描获取紫外分光光度值，绘制标曲。
请问0.5%的EB溶液，注射量是多少?2022-11-24 16:21:47
您好，须参照实验动物种属而定，建议拨打400-968-6088转2与我司技术支持联系。