The browning and mobilization of subcutaneous white adipose tissue supports efficient skin repair
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Author：
Junrong Cai, Yuping Quan, Shaowei Zhu, Jiayan Lin, Qian Zhang, Juzi Liu, Zhuokai Liang, Yunjun Liao, Wenqing Jiang, Yufei He, Ting Su, Feng Lu
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Cell Metabolism
Reinforcing Gelatin Hydrogels via In Situ Phase Separation and Enhanced Interphase Bonding for Advanced 3D Fabrication
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Author：
Chunling Ren, Wanqi Chen, Yun Liao, Yangguang Huang, Changlong Yu, Ting Chen, Qingmei Zeng, Yunlong Yang, Rongkun Huang, Tuan Liu, Li Jiang, Bingkun Bao, Linyong Zhu, Qiuning Lin
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ADVANCED MATERIALS
Immune-modulated adhesive hydrogel for enhancing osteochondral graft adhesion and cartilage repair
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Author：
Jiaqi Zhou, Xiongfa Ji, Yu Xue, Wenjie Yang, Guoqing Zhong, Zhiyang Zhou, Xingmei Chen, Zehua Lei, Teliang Lu, Yu Zhang, Ji Liu, Limin Ma
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Bioactive Materials
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism
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Author：
Dong Zheng-Lin, Jiao Xin, Wang Zeng-Guang, Yuan Kai, Yang Yi-Qi, Wang Yao, Li Yun-Tao, Wang Tian-Chang, Kan Tian-You, Wang Jian, Tao Hai-Rong
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Military Medical Research
Semi-synthetic chondroitin sulfate CS-semi5 upregulates miR-122-5p, conferring a therapeutic effect on osteoarthritis via the p38/MMP13 pathway
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Author：
Xiang Li, Ya Zhou, Xuefeng Chen, Hongjun Wang, Shuang Yang, Jun Yang, Yunfeng Song, Zhehui Zhao, Haijing Zhang, Lianqiu Wu
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Acta Pharmaceutica Sinica B
Zwitterion-Lubricated Hydrogel Microspheres Encapsulated with Metformin Ameliorate Age-Associated Osteoarthritis
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Author：
Jiahui Hou, Yanpeng Lin, Chencheng Zhu, Yupeng Chen, Rongmin Lin, Hancheng Lin, Dahai Liu, Daogang Guan, Bin Yu, Jun Wang, Hangtian Wu, Zhuang Cui
Publish_to：
Advanced Science
LIPUS activated piezoelectric pPLLA/SrSiO3 composite scaffold promotes osteochondral regeneration through P2RX1 mediated Ca2+ signaling pathway
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Author：
Chengxiao Liu, Bin Yu, Zhaowenbin Zhang, Lefeng Su, Ruiqing Wang, Yu Jin, Weiming Guo, Ruomei Li, Zhen Zeng, Peng Mei, Jiang Chang, Lunguo Xia, Chen Yang, Bing Fang
Characterization of Metalaxyl-induced notochord toxicity based on biochemical and transcriptomics in zebrafish (Danio rerio) model
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Author：
Xingkun Tang, Yunlong Meng, Haining Li, Kangyu Liu, Xinyao Wang, Zilin Zhong, Junsong Ye, Jianjun Chen
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JOURNAL OF HAZARDOUS MATERIALS
Endogenous hydrogen sulfide accelerated trauma-induced heterotopic ossification through the Ca2+/ERK pathway-enhanced aberrant osteogenic activity
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Author：
Zhengqiang Yuan, Juehong Li, Kuangyu He, Ziyang Sun, Gang Luo, Hang Liu, Jinlei Dong, Chao Zhou, Haomin Cui, Cunyi Fan
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Redox Biology
Succinate exacerbates mastitis in mice via extracellular vesicles derived from the gut microbiota: a potential new mechanism for mastitis
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Author：
Qiu Min, Ye Cong, Zhao Xiaotong, Zou Chenyu, Tang Ruibo, Xie Jiaxin, Liu Yiheng, Hu Yubo, Hu Xiaoyu, Zhang Naisheng, Fu Yunhe, Wang Jun, Zhao Caijun
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JOURNAL OF NANOBIOTECHNOLOGY
Conditional sequential delivery of ginkgetin and rapamycin orchestrates inflammation and autophagy to alleviate intervertebral disc degeneration
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Author：
Jiaoxiang Chen, Xin Gan, Shenkai Su, Sizhe Jiao, Zailing Gong, Ziqiang Liu, Xiaopei Wu, Jun Jiang, Jiaming Zhang, Junlai Wan
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JOURNAL OF CONTROLLED RELEASE
BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration
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Author：
Guangzhi Zhang, Lei Li, Zhili Yang, Zhenyu Cao, Xuchang Hu, Yonggang Wang, Xuewen Kang
Angelica sinensis polysaccharides mitigate cadmium-induced apoptosis in layer chicken chondrocytes by inhibiting the JNK signaling pathway
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Author：
Xishuai Tong, Guoshuai Wang, Xinrui Zhao, Jiatao Zhou, Panting Wang, Han Xia, Jianchun Bian, Xuezhong Liu, Yan Yuan, Hui Zou, Zongping Liu, Jianhong Gu
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Digoxin protects against intervertebral disc degeneration via TNF/NF-百B and LRP4 signaling
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Author：
Qunbo Meng, Kaiwen Liu, Zhenchuan Liu, Jinbo Liu, Ziyu Tian, Shanshan Qin, Jianlu Wei, Lei Cheng
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Frontiers in Immunology
LncRNA SNHG1 enhances cartilage regeneration by modulating chondrogenic differentiation and angiogenesis potentials of JBMMSCs via mitochondrial function regulation
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Author：
Liu Hua, Liu Huina, Yang Qiubo, Fan Zhipeng
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Stem Cell Research & Therapy
Vitamin K2 ameliorates osteoarthritis by suppressing ferroptosis and extracellular matrix degradation through activation GPX4’s dual functions
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Author：
Qi He, Yuewei Lin, Baihao Chen, Chuyi Chen, Jiaxu Zeng, Xiangyun Dou, Dongling Cai, Chi Zhou, Haibin Wang
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BIOMEDICINE & PHARMACOTHERAPY
Curcumenol regulates Histone H3K27me3 demethylases KDM6B affecting Succinic acid metabolism to alleviate cartilage degeneration in knee osteoarthritis
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Author：
Weijian Chen, Jiacong Xiao, Yi Zhou, Weinian Liu, Junde Jian, Jiyong Yang, Bohao Chen, Zhilong Ye, Jun Liu, Xuemeng Xu, Tao Jiang, Haibin Wang, Wengang Liu
Publish_to：
PHYTOMEDICINE
Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment
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Author：
Guangjie Li, Fei He, Jianbao Feng, Ge Xu, Chengye Wu, Yufei Qiao, Yang Liu, Hanlin Chen, Pengcheng Du, Jizeng Wang
Publish_to：
International Journal of Nanomedicine
p21 Regulates Wnt-Notch balance via DREAM/MMB/Rb-E2F1 and maintains intestinal stem cell homeostasis
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Author：
Jiang Liangxia, Tian Jie, Yang Jun, Luo Ronggang, Zhang Yongjin, Shao Chihao, Guo Bing, Wu Xiaoming, Dan Juhua, Luo Ying
Publish_to：
Cell Death Discovery
Baicalein-loaded porous silk fibroin microspheres modulate the senescence of nucleus pulposus cells through the NF-κB signaling pathway
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Author：
Yanchi Gan, Jiahui He, Yan Gong, Zixian Wu, De Liang, Gengyang Shen, Hui Ren, Xiaobing Jiang, Zhaojun Cheng
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
A pH-responsive novel delivery system utilizing carbon quantum dots loaded with PT2385 for targeted inhibition of HIF-2α in the treatment of osteoarthritis
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Author：
Cheng-Ming Zhang, Yu-Xin Kang, Si-Yu Zheng, Yang Liu, Meng-Rou Liu, Gai-Ge Wu, Li Guo, Peng-Cui Li, Rui-Peng Zhao, Qian-Qian Duan, Shao-Wei Wang, Xiao-Chun Wei
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
Moringin alleviates DSS-induced ulcerative colitis in mice by regulating Nrf2/NF-κB pathway and PI3K/AKT/mTOR pathway
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Author：
Tongbo Zhang, Linxian Zhao, Meng Xu, Peng Jiang, Kai Zhang
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INTERNATIONAL IMMUNOPHARMACOLOGY
AFK-PD alleviated osteoarthritis progression by chondroprotective and anti-inflammatory activity
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Author：
Qian Zhuang, Xu Jie, Zhang Lei, Deng Qian, Fan Zhenlin, Guo Xueqiang, Liang Zhuo, Wang Weiyun, Wang Lei, Liao Xiaohua, Ren Wenjie
Publish_to：
Frontiers in Pharmacology
MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway
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Author：
Hantao Ye, Tingwen Cai, Yang Shen, Lin Zhao, Haojie Zhang, Jianxin Yang, Feida Li, Jiaoxiang Chen, Xiaolong Shui
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier
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Author：
Yuzhu Di, Hui Li, Jia Yang, Minghao Feng, Shuang Wang, Wanying Li, Xiuqing Wang, Yuxin Zhu, Yan Shi, Rennan Feng, Bo Qu
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Histopathology and transcriptome profiling reveal features of immune responses in gills and intestine induced by Spring viremia of carp virus
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Author：
Ping Ouyang, Qiunan Li, Shuya Liu, Yankai Li, Shuhan Li, Yongheng Zhou, Peng jia, Defang Chen, Xiaoli Huang, Yi Geng
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
Thermo-responsible PNIPAM-grafted polystyrene microspheres for mesenchymal stem cells culture and detachment
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Author：
Yuanyuan Zhao, Zida Cao, Jingwei Zhang, Jia Tian, Haibo Cai
Publish_to：
Biomedical Materials
Overexpressed miR-486 in bone marrow mesenchymal stem cells represses urethral fibrosis and targets Col13a1 in urethral stricture rats
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Author：
Yali Xu, Lihong Huang, Zhixin Qiu, Jiaqi Zhang, Xueyi Xue, Junshan Lin
Publish_to：
Journal of Cell Communication and Signaling
METTL3 inhibits BMSC apoptosis and facilitates osteonecrosis repair via an m6A-IGF2BP2-dependent mechanism
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Author：
Zhihong Xie, Hong Luo, Tao Wang, Lei Wang, Jian Zhang, Wentao Dong, Gang Liu, Fanchao Li, Qinglin Kang, Xuesong Zhu, Fei Zhang, Wuxun Peng
Cyclic mechanical stress promotes osteogenic differentiation of periodontal ligament stem cells via KAT2A-mediated succinylation of WDR5
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Author：
Xiaofeng Guo, Nanshan Zhuge
Publish_to：
TISSUE & CELL
Deer antler stem cells immortalization by modulation of hTERT and the small extracellular vesicles characters
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Publish_to：
Frontiers in Veterinary Science
Effects of Oligomeric Proanthocyanidins on Cadmium-Induced Extracellular Matrix Damage via Inhibiting the ERK1/2 Signaling Pathway in Chicken Chondrocytes
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Author：
Jianhong Gu, Dan Liu, Anqing Gong, Xinrui Zhao, Jiatao Zhou, Panting Wang, Han Xia, Ruilong Song, Yonggang Ma, Hui Zou, Muhammad Azhar Memon, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zongping Liu, Xishuai Tong
Publish_to：
Veterinary Sciences
中文
英语
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多聚甲醇可以固定嘛？时间也是5min?对于6孔板，如何掌握加入各种试剂的量？即每孔加入多少ml?2023-08-06 16:21:24
您好，该染色液可以同时对糖胺聚糖和糖蛋白进行染色，但是糖胺聚糖易溶于水需要使用甲醇固定，糖蛋白可以使用多聚甲醛室温固定30min替代甲醇固定。对于六孔板建议每孔添加1ml。