中文
英语
谷草转氨酶(GOT/AST)活性检测试剂盒
检测方法:可见分光光度法 Spectrophotometer
英文名称:Glutamic-oxalacetic Transaminase(GOT) Activity Assay Kit
储存条件:Store at 2-8℃，6 months
产品简介
| 中文名称 | 谷草转氨酶(GOT/AST)活性检测试剂盒 |
| 英文名称 | Glutamic-oxalacetic Transaminase(GOT) Activity Assay Kit |
| 检测方法 | 可见分光光度法 Spectrophotometer |
| 储存条件 | Store at 2-8℃，6 months |
| 规格 | 50T/24S |
| 单位 | 盒 |
测定意义：GOT（ 2.6.1.1）广泛存在于动物、植物、微生物和培养细胞中，催化可逆转氨基反应，是氨基酸代谢的重要酶。此外，GOT 在心肌细胞中含量最高，临床上一般常作为心肌梗塞和心肌炎的辅助检查。肝脏损害时其血清浓度也可升高。
测定原理：GOT 催化 α-同戊二酸和天门冬氨酸发生转氨基反应，生成谷氨酸和草酰乙酸，草酰乙酸进一步自行脱羧生成丙酮酸；丙酮酸可与2,4-二硝基苯肼反应生成2,4-二硝基苯腙，在碱性条件下显棕红色；测定505nm 吸光度的变化，即可计算GOT 酶活力。
需自备的仪器和用品：可见分光光度计、水浴锅、台式离心机、可调式移液器、1 mL 玻璃比色皿、研钵、冰和蒸馏水。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Tingting Ma, Huanli Cheng, Tongxi Li, Yifan Chen, Tianying Cai, Junjie Bai, Ziming Wu, Xianming Xia, Tiancheng Liang, Yichao Du, Wenguang Fu
IF：
5.3070
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
35667255
Gynostemma Pentaphyllum ameliorates CCl4-induced liver injury via PDK1/Bcl-2 pathway with comprehensive analysis of network pharmacology and transcriptomics
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Author：
Linlan Hu, Xin Zhao, Xian He, Yafei Guo, Hanxiao Cheng, Shaoting Chen, Guangde Zhou, Jiabo Wang, Yawen Lu
IF：
5.3000
Publish_to：
Chinese Medicine
PMID：
38750545
Lactoferrin Alleviates Acute Alcoholic Liver Injury by Improving Redox-Stress Response Capacity in Female C57BL/6J Mice
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Author：
Deming Li, Zhiqiang Hu, Qian He, Yaxin Guo, Yu Chong, Jiaying Xu, Liqiang Qin
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
34873911
The Molecular Mechanism Underlying the Therapeutic Effect of Dihydromyricetin on Type 2 Diabetes Mellitus Based on Network Pharmacology, Molecular Docking, and Transcriptomics
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Author：
Xinnian Wen, Chenghao Lv, Runze Zhou, Yixue Wang, Xixin Zhou, Si Qin
IF：
5.2000
Publish_to：
Foods
PMID：
38275711
Pyrroloquinoline quinone ameliorates liver injury in mice induced by cyclophosphamide
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Author：
Qian Li, Yang Fei, Lin Xinhui, Jiang Su, Zhang Yun, Tang Yunping
IF：
5.1900
Publish_to：
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
PMID：
34997497
Design,synthesis,and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea
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Author：
Zhongcheng Yang, Zhijun Cao, Wenxin Wang, Ya Chen, Wanqiu Huang, Shixuan Jiao, Siliang Chen, Lianru Chen, Yuxia Liu, Jianming Mao, Luyong Zhang, Zheng Li
IF：
5.1000
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
37300962
Hepatoprotective effects of peach gum polysaccharides against alcoholic liver injury: moderation of oxidative stress and promotion of lipid metabolism
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Author：
Bingjie Zhou, Pinpin Liu, Xiangao Yao, Huijie Cao, Hang Zhu, Qiao Wang, Yan Liu, Min Fang, Yongning Wu, Zhiyong Gong
IF：
5.0000
Publish_to：
Frontiers in Nutrition
PMID：
38283909
CaMKII regulates the proteins TPM1 and MYOM2 and promotes diacetylmorphine-induced abnormal cardiac rhythms
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Author：
Ji Min, Su Liping, Liu Li, Zhuang Mengjie, Xiao Jinling, Guan Yaling, Zhu Sensen, Ma Lijuan, Pu Hongwei
IF：
4.9960
Publish_to：
Scientific Reports
PMID：
37037889
Accurate Long-Read RNA Sequencing Analysis Reveals the Key Pathways and Candidate Genes under Drought Stress in the Seed Germination Stage in Faba Bean
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Author：
Xin Wen, Changyan Liu, Fangwen Yang, Zhengxin Wei, Li Li, Hongwei Chen, Xuesong Han, Chunhai Jiao, Aihua Sha
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
39201560
Scutellarin inhibits inflammatory PANoptosis by diminishing mitochondrial ROS generation and blocking PANoptosome formation
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Author：
Tao Yuan, Hai-Yan Yang, Ya-Ping Li, Zi-Jian Shi, Zhi-Ya Zhou, Yi-Ping You, Hua-Yu Ke, Liang Yan, Li-Hui Xu, Dong-Yun Ouyang, Xian-Hui He, Qing-Bing Zha
IF：
4.8000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
39029229
Commensal Bacillus siamensis LF4 induces antimicrobial peptides expression via TLRs and NLRs signaling pathways in intestinal epithelial cells of Lateolabrax maculatus
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Author：
Zi-Yan Liu, Hong-Ling Yang, Cheng-Ye Wei, Guo-He Cai, Ji-Dan Ye, Chun-Xiao Zhang, Yun-Zhang Sun
IF：
4.7000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
36828198
Study on Dihydromyricetin Improving Aflatoxin Induced Liver Injury Based on Network Pharmacology and Molecular Docking
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Author：
Xiaoying Zhu, Silu Liu, Hongyan Pei, Weijia Chen, Ying Zong, Yan Zhao, Jianming Li, Rui Du, Zhongmei He
IF：
4.6000
Publish_to：
Toxics
PMID：
37755770
Transcriptomics and metabolomics together reveal the underlying mechanism of heroin hepatotoxicity
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Author：
Yingbiao Yue, Lei Zou, Jie Tao, Lin Yin, Zhenrong Xie, Yu Xia, Zunyue Zhang, Kunhua Wang, Mei Zhu
IF：
4.5710
Publish_to：
TOXICOLOGY
PMID：
36502556
Enhanced Immune Response Improves Resistance to Cadmium Stress in Triploid Crucian Carp
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Author：
Wen-bin Liu, Min-meng Wang, Liu-ye Dai, Sheng-hua Dong, Xiu-dan Yuan, Shu-li Yuan, Yi Tang, Jin-hui Liu, Liang-yue Peng, Ya-mei Xiao
IF：
4.5660
Publish_to：
Frontiers in Physiology
PMID：
34149447
Succinic Acid Ameliorates Concanavalin A-Induced Hepatitis by Altering the Inflammatory Microenvironment and Expression of BCL-2 Family Proteins
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Author：
Cai Ying, Chen Zhiyuan, Chen Ermei, Zhang Dongdong, Wei Tao, Sun Mingyang, Lian Yifan
IF：
4.5000
Publish_to：
INFLAMMATION
PMID：
38613638
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis
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Author：
Hu Yile, Xing Yihao, Fan Gaolu, Xie Huaxia, Zhao Qingzan, Liu Ling
IF：
4.4000
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Frontiers in Pharmacology
PMID：
38841361
Rhubarb granule promotes diethylnitrosamine-induced liver tumorigenesis by activating the oxidative branch of pentose phosphate pathway via G6PD in rats
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Author：
Hongwu Huang, Zhenzhen Liu, Xiaoru Qi, Nailong Gao, Jianguo Chang, Miaomiao Yang, Sha Na, Yanyan Liu, Rui Song, Lu Li, Guangliang Chen, Hui Zhou
IF：
4.3600
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
34343647
A novel vesicular stomatitis virus armed with IL-2 mimic for oncolytic therapy
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Author：
Manman Wu, Yiwei Wang, Chuanjian Wu, Huang Huang, Xinyuan Zhou, Jun Wang, Sidong Xiong, Chunsheng Dong
IF：
4.3000
Publish_to：
VIROLOGICA SINICA
PMID：
39299564
TBK1 participates in glutaminolysis by mediating the phosphorylation of RIPK3 to promote endotoxin tolerance
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Author：
Lehan Pan, Lian Yang, Zhujun Yi, Wenfeng Zhang, Jianping Gong
IF：
4.1740
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
35533409
Effects of rosemary extract and its residue on production, immune performance, and gut microbiota in geese
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Author：
Yuzhi Huang, Lanmeng Xu, Hang He, Lijuan Peng, Qinfeng Liao, Kun Wan, Simeng Qin, Lijing Cao, Jie Zhang
IF：
4.0000
Publish_to：
Frontiers in Microbiology
PMID：
39845044
Zearalenone Enhances TSST-1 Production by Intestinal Staphylococcus and Increases Uterine Immune Stress in Rats
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Author：
Ruiqi Zhang, Bingxin Huangfu, Tongxiao Xu, Victor Olusola Opatola, Qiushi Ban, Kunlun Huang, Xiaoyun He
IF：
3.9000
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
39586525
Liver and Kidney Surgical Anatomy to Verify the Effect of miR-221 on Organ Damage in Septic Rats
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Author：
Bingtao Shi, Jialing Zhang, QiaoGe Chen
IF：
3.8220
Publish_to：
Journal of Healthcare Engineering
PMID：
35186224
Metformin ameliorates liver fibrosis induced by congestive hepatopathy via the mTOR/HIF-1α signaling pathway
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Author：
Jing Yang, Suxin Li, Shengyan Liu, Yuehui Zhang, Dongqi Shen, Peiju Wang, Xiaowei Dang
IF：
3.8000
Publish_to：
Annals of Hepatology
PMID：
37451514
Epigallocatechin-3-gallate Alleviates Vanadium-Induced Reduction of Antioxidant Capacity via Keap1-Nrf2-sMaf Pathway in the Liver, Kidney, and Ovary of Laying Hens
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Author：
Ma Yan, Shi Yizhen, Wu Qiujue, Ma Wenfeng
IF：
3.7380
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BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
33405082
Hif3α Plays Key Roles in the Progression of Alzheimer’s Disease Caused by Circadian Rhythm Disruption through Regulating the m6A/KDM3A/TGF-β1 Axis
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Author：
Xinrui Li, Zhengkun Han, Huiying Li
IF：
3.6000
Publish_to：
Biology-Basel
PMID：
38927292
Effects of myo-inositol on regulating glucose and lipid metabolism and alternative splicing events coexpressed with lncRNAs in the liver tissues of diabetic mice
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Author：
Jin'e Li, Qiulan Huang, Qin Nie, Yunfei Luo, Haixia Zeng, Yuying Zhang, Xiaoju He, Jianping Liu
IF：
3.4000
Publish_to：
Heliyon
PMID：
38933931
USP33 promotes nonalcoholic fatty acid disease-associated fibrosis in gerbils via the c-myc signaling
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Author：
Xianfu Ke, Huiying Hu, Qianyu Peng, Huazhong Ying, Xiaofeng Chu
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
37267862
MSR1-dependent efferocytosis improved ischemia-reperfusion injury following aged-donor liver transplantation in mice by regulating the pro-resolving polarisation of macrophages
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Author：
Xue-song Xu, Tao Liu, Ya-jun Chen, Xin-yi Wu, Ming-xiang Cheng, Jin-zheng Li
IF：
3.3000
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
39168433
Pharmacological inhibition of Rac1 attenuates myocardial abnormalities in tail-suspended mice
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Author：
Li Huili, Cao Ting, Ding Weimin, Liang Liwen, Fan Guo-Chang, Qu Lina, Peng Tianqing
IF：
3.2160
Publish_to：
Journal of Cardiovascular Translational Research
PMID：
35088374
β-hydroxybutyrate administration improves liver injury and metabolic abnormality in postnatal growth retardation piglets
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Author：
Chengming Wang, Nan Wang, Yuankun Deng, Andong Zha, Junyao Li, Bie Tan, Ming Qi, Jing Wang, Yulong Yin
IF：
3.2000
Publish_to：
Frontiers in Veterinary Science
PMID：
38026634
Protective effects of SCFAs on organ injury and gut microbiota modulation in heat-stressed rats
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Author：
Yang Zhan, Tang Chengliang, Sun Xuewei, Wu Zihan, Zhu Xiaojing, Cui Qian, Zhang Ruonan, Zhang Xinrui, Su Yunxin, Mao Yinghua, Wang Chunhui, Zheng Feng, Zhu Jin
IF：
3.0000
Publish_to：
ANNALS OF MICROBIOLOGY
PMID：
Microbial creation of β-Nicotinamide mononucleotide and its regulation of lipid metabolism in the liver of high-fat diet mice
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Author：
Xutong Tian, Youyan Rong, Juyue Luo, Yaping Zhao, Tiantian Zhou, Yu Zeng, Kai Hong, Liang Jiang, Jianying Yang, Yumeng Li, Xin Wu
IF：
2.8000
Publish_to：
CELL BIOCHEMISTRY AND FUNCTION
PMID：
38953407
Baicalin inhibits oxidative injures of mouse uterine tissue induced by acute heat stress through activating the Keap1/Nrf2 signaling pathway
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Author：
Huatao Li, Xia Cong, Wenhui Yu, Zhongling Jiang, Kaiqiang Fu, Rongfeng Cao, Wenru Tian, Yanni Feng
IF：
2.5540
Publish_to：
RESEARCH IN VETERINARY SCIENCE
PMID：
36270181
Yak DEFB123 alleviates lung injury caused by Klebsiella pneumoniae through MAPKs signaling pathway
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Author：
Nanchi Zhang, Yao Zheng, Yong Wei, Li Wang, Xiwen Chen, Juan Li
IF：
2.4000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
39265281
Metabolic exhaustion and casein kinase 1汐 drive deguelin-induced premature red blood cell death
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Author：
Mohammad A. Alfhili, Jawaher Alsughayyir
IF：
1.8000
Publish_to：
XENOBIOTICA
PMID：
37590011
Krill Oil Ameliorates Liver Injury in Diabetic Mice by Activating Antioxidant Capacity and Inhibiting Ferroptosis
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Author：
Huali Meng, Jie Li, Yu Yang, Yan Zheng, Shue Wang, Xin Guo, Lei Du, Hao Wu
IF：
1.6000
Publish_to：
Journal of Oleo Science
PMID：
39085082
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