中文
英语
产品简介
| 中文名称 | Gluta固定液(电镜专用，4%) |
| 英文名称 | Glutaraldehyde，4%(EM Grade) |
| 储存条件 | 2-8℃，避光保存，有效期6个月。 |
| 规格 | 100ml 500ml |
| 单位 | 瓶 |
固定的目的在于保存细胞和组织的原有形态结构，固定剂能阻止内源性溶酶体酶对自身组织和细胞的自溶、抑制细菌和霉菌的生长。固定液主要分为醛类固定液、汞类固定液、醇类固定液、氧化剂类固定液、苦味酸盐类固定液等，较为常用的是醛基和醇基固定液。
Gluta固定液 (电镜专用,4%) 能固定更多的结构和化学成分，因此被固定的成分在制样过程中就不易流失，一直会保留在原位，适用于电镜观察样本固定。在光镜下观察各结构着色普遍偏深，且难以将颜色褪去，辨识度反而低于常规固定液。而且由于固定效果稳定，固定后组织致密，抗原掩蔽性高于常规固定液，用于常规染色需适当调整染色步骤。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Yishuai Lin, Ying Zhang, Shixing Liu, Dandan Ye, Liqiong Chen, Na Huang, Weiliang Zeng, Wenli Liao, Yizhou Zhan, Tieli Zhou, Jianming Cao
IF：
5.2210
Publish_to：
Frontiers in Chemistry
PMID：
34900948
The effect of organic acids on high-moisture extrusion of soy protein isolate: Comparison between monocarboxylic acid and polycarboxylic acids
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Author：
Haoqiang Wang, Wen Li, Yihui Gong, Yujia Xu, Shunjing Luo, Xiuting Hu, Chengmei Liu
IF：
5.2000
Publish_to：
Food Bioscience
PMID：
Theabrownin remodels the circadian rhythm disorder of intestinal microbiota induced by high-fat diet to alleviate obesity in mice
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Author：
Chunyan Zhao, Shuwen Lei, hong Zhao, Zelin Li, Yue Miao, Chun-xiu Peng, Jiashun Gong
IF：
5.1000
Publish_to：
Food & Function
PMID：
39866149
Upregulation of GLT25D1 in Hepatic Stellate Cells Promotes Liver Fibrosis via the TGF-β1/SMAD3 Pathway In Vivo and In vitro
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Author：
Shiwei Wang, Lingling He, Fan Xiao, Meixin Gao, Herui Wei, Junru Yang, Yang Shu, Fuyang Zhang, Xiaohui Ye, Ping Li, Xiaohua Hao, Xingang Zhou, Hongshan Wei
IF：
5.0650
Publish_to：
Journal of Clinical and Translational Hepatology
PMID：
36406310
Antibacterial activity and multi-target mechanism of harmane against Escherichia coli O157:H7 and its application on ready-to-eat leafy greens
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Author：
Meixia Sui, Jiaoyue Zhang, Jingying Li, Li Wang, Zhenzhen Gao, Wenjia Dan, Jiangkun Dai
IF：
5.0000
Publish_to：
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
PMID：
39862743
Collagen Membrane Derived from Fish Scales for Application in Bone Tissue Engineering
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Author：
Liang Chen, Guoping Cheng, Shu Meng, Yi Ding
IF：
4.9670
Publish_to：
Polymers
PMID：
35808577
Notch3-Mediated mTOR Signaling Pathway Is Involved in High Glucose-Induced Autophagy in Bovine Kidney Epithelial Cells
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Author：
Yaocheng Cui, Jing Fang, Hongrui Guo, Hengmin Cui, Junliang Deng, Shumin Yu, Liping Gou, Fengyuan Wang, Xiaoping Ma, Zhihua Ren, Yue Xie, Yi Geng, Ya Wang, Zhicai Zuo
IF：
4.9270
Publish_to：
MOLECULES
PMID：
35630598
Chitin Synthase Is Required for Cuticle Formation and Molting in the Chinese Mitten Crab Eriocheir sinensis
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Author：
Ting Zhang, Yuning Hu, Siyu Lu, Yanfei Deng, Huimin Zhang, Yanhua Zhao, Yawen Yu, Hongbin Huang, Jun Zhou, Xuguang Li
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
40076977
IGF2 contributes to the immunomodulatory effects of exosomes from endometrial regenerative cells on experimental colitis
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Author：
Qiang Chen, Bo Shao, Yi-ni Xu, Xiang Li, Shao-hua Ren, Hong-da Wang, Jing-yi Zhang, Cheng-lu Sun, Tong Liu, Yi-yi Xiao, Peng-yu Zhao, Guang-mei Yang, Xu Liu, Hao Wang
IF：
4.8000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
39079347
Aspirin/PLGA coated 3D-printed Ti-6Al-4V alloy modulate macrophage polarization to enhance osteoblast differentiation and osseointegration
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Author：
You Yapeng, Wang Wanmeng, Li Ying, Song Yunjia, Jiao Jian, Wang Yao, Chen Bo, Liu Jialin, Qi Hui, Liang Yu
IF：
4.7270
Publish_to：
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
PMID：
36209337
The Effects of Different Reheating Methods on the Quality of Pre-Cooked Braised Chicken
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Author：
Sihao Liu, Yu Wang, Hewei Shi, Huijuan Zhao, Jiansheng Zhao, Shaohua Meng, Shifeng Shen, Junguang Li
IF：
4.7000
Publish_to：
Foods
PMID：
40077573
Tumor-Originated Exosomal hsa-miR-3937 as a Minimally Invasive Early Biomarker for Liquid Biopsy of Colorectal Cancer
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Author：
Dan Qiao, Chenzheng Gu, Weiwei Wang, Wenhui Yan, Chenfei Jiang, Jingwen Hu, Anquan Shang, Jian Guo
IF：
4.5010
Publish_to：
Journal of Oncology
PMID：
35602301
Low expression of FOXP2 predicts poor survival and targets caspase-1 to inhibit cell pyroptosis in colorectal cancer
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Author：
Peng Liao, Wu-hua Huang, Li Cao, Tao Wang, Li-ming Chen
IF：
4.4780
Publish_to：
Journal of Cancer
PMID：
35281860
Lipopolysaccharide-regulated RNF31/NRF2 axis in colonic epithelial cells mediates homeostasis of the intestinal barrier in ulcerative colitis
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Author：
Chao-Tao Tang, Zi-de Liu, Peng Wang, Chun-Yan Zeng, You-Xiang Chen
IF：
4.4000
Publish_to：
CELLULAR SIGNALLING
PMID：
39437901
Quorum Quenching Enzyme (PF-1240) Capable to Degrade AHLs as a Candidate for Inhibiting Quorum Sensing in Food Spoilage Bacterium Hafnia alvei
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Author：
Yue Shen, Fangchao Cui, Dangfeng Wang, Tingting Li, Jianrong Li
IF：
4.3500
Publish_to：
Foods
PMID：
34828982
Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)-mediated ER stress crosstalk with autophagy is involved in tris(2-chloroethyl) phosphate stress-induced cardiac fibrosis
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Author：
Xuan Xiong, Xiaoqin Zhang, Yuan Zhang, Jiaqi Xie, Yuan Bian, Qinan Yin, Rongsheng Tong, Dongke Yu, Lingai Pan
IF：
4.3360
Publish_to：
JOURNAL OF INORGANIC BIOCHEMISTRY
PMID：
36087434
Eryptosis is an indicator of hematotoxicity in the risk assessment of environmental amorphous silica nanoparticles exposure: The role of macromolecule corona
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Author：
Zhangde Chen, Bingwei Yang, Ziyi Yan, Erqun Song, Yang Song
IF：
4.2710
Publish_to：
TOXICOLOGY LETTERS
PMID：
35870742
Acetaldehyde dehydrogenase 2 attenuates lipopolysaccharide -induced endothelial barrier damage by inhibiting mitochondrial fission in sepsis-associated encephalopathy
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Author：
Shasha Wang, Zhongyi Liu, Rong Li, Liya Wang, Yue Wu, Weiping Zhang, Ying Yu
IF：
4.2000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
40054720
Construction of PCL-collagen@PCL@PCL-gelatin three-layer small diameter artificial vascular grafts by electrospinning
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Author：
Xingjian Lu, Hao Zou, Xiaokun Liao, Yue Xiong, Xiaoyan Hu, Jun Cao, Jiaqi Pan, Chaorong Li, Yingying Zheng
IF：
4.1030
Publish_to：
Biomedical Materials
PMID：
36374009
Self-Emulsifying Drug Delivery System Enhances Tissue Distribution of Cinnamaldehyde by Altering the Properties of the Mucus Layer
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Author：
Liu Liu, Cao Wenxuan, Xia Mengqiu, Tian Chunling, Wu Wenqing, Cai Ye, Chu Xiaoqin
IF：
4.0260
Publish_to：
AAPS PHARMSCITECH
PMID：
36131215
Toxicity of imidazoles ionic liquid [C16mim]Cl to Hela cells
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Author：
Xiaohua Xi,Ruyan Wan,Peijin Wang,Weiran Huo,Hui Do
IF：
3.9740
Publish_to：
Ecotoxicology and Environmental Safety
PMID：
30015186
Effects of Arginine-calcium carbonate pretreatment on the remineralizing and bonding performance of phosphorylated dentin
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Author：
Jingyu Ding, Xuanyan Zhu, Qi Lin, Lingkang Lin, Zhengyuan Yang, Song Zhu
IF：
3.9000
Publish_to：
Journal of the Mechanical Behavior of Biomedical Materials
PMID：
36774762
Synthesis,antibacterial activity and action mechanism of silver-based nanomaterials with thermosensitive polymer-decorated graphene oxide as a stable support
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Author：
Shuying Liu, Dongyan Zhang, Weihui Chen, Xiuran Wang, Haixun Ji, Yuqin Fu, Changli Lü
IF：
3.8000
Publish_to：
Materials Today Communications
PMID：
Jian Pi Sheng Sui Gao (JPSSG) alleviation of skeletal myoblast cell apoptosis, oxidative stress, and mitochondrial dysfunction to improve cancer-related fatigue in an AMPK-SIRT1- and HIF-1-dependent manner
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Author：
Min Xiao, Wei Guo, Chi Zhang, Yukun Zhu, Zhiling Li, Cui Shao, Jiling Jiang, Zhenjiang Yang, Jianyong Zhang, Lizhu Lin
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
36846003
YTHDF2 promotes DNA damage repair by positively regulating the histone methyltransferase SETDB1 in spermatogonia
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Author：
Guo Ming, Li Xueliang, Li Tianjiao, Liu Ruifang, Pang Weijun, Luo Jun, Zeng Wenxian, Zheng Yi
IF：
3.6000
Publish_to：
BIOLOGY OF REPRODUCTION
PMID：
37812443
Targeting proteasome enhances anticancer activity of oncolytic HSV-1 in colorectal cancer
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Author：
Xiaxi Li, Wei Hu, Jiangang Shen, Mingsong Li, Wei Gong
IF：
3.5130
Publish_to：
VIROLOGY
PMID：
36434905
Comparative Study of 3D-Printed Porous Titanium Alloy with Rod Designs of Three Different Geometric Structures for Orthopaedic Implantation
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Author：
Li Jiaxin, Zhong Haozhang, Cao Bojun, Ran Zhaoyang, Tan Jia, Deng Liang, Hao Yongqiang, Yan Jinglong
IF：
3.5000
Publish_to：
Acta Metallurgica Sinica-English Letters
PMID：
Occurrence of disinfectant-resistant bacteria in a fresh-cut vegetables processing facility and their role in protecting Salmonella enteritidis
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Author：
Jing-Guo Xu, Jiao Meng, Wen-Jing Bao, Jia-Mu Kang, Jing-Yu Chen, Bei-Zhong Han
IF：
3.3610
Publish_to：
RSC Advances
PMID：
35423506
Trpc5-regulated AMPKα/mTOR autophagy pathway is associated with glucose metabolism disorders in low birth weight mice under overnutrition
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Author：
Fei Zhou, Linlin Yang, Linquan Yang, Xing Wang, Na Guo, Wenwen Sun, Huijuan Ma
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
36122525
Cell membrane skeletal protein 4.1R participates in entry of Zika virus into cells
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Author：
Shan Su, Xin Liu, Ren-Rong Tian, Kai-Xuan Qiao, Chang-Bo Zheng, Wen-Cong Gao, Liu-Meng Yang, Qiao-Zhen Kang, Yong-Tang Zheng
IF：
3.3030
Publish_to：
VIRUS RESEARCH
PMID：
34637814
Involvement of TOB1 on autophagy in gastric cancer AGS cells via decreasing the activation of AKT/mTOR signaling pathway
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Author：
Dong Wang, Yunlong Li, Shuning Sui, Mengdi Cai, Kexian Dong, Ping Wang, Xiao Liang, Songbin Fu, Jingcui Yu
IF：
3.0610
Publish_to：
PeerJ
PMID：
35186488
Physiological analysis and transcriptome sequencing of a delayed-green leaf mutant ‘Duojiao’ of ornamental crabapple (Malus sp.)
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Author：
Zhang Lulu, Zhang Junkang, Mao Yunfei, Yin Yijun, Shen Xiang
IF：
3.0230
Publish_to：
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
PMID：
36484024
Using a safe and effective fixative to improve the immunofluorescence staining of bacteria
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Author：
Jian Sun, Yuantian Mao, Lanyu Cui, Yongqiang Cao, Zhao Li, Min Ling, Xiaoping Xu, Shengbin He
IF：
3.0090
Publish_to：
Methods and Applications in Fluorescence
PMID：
33853048
Stevioside reduces inflammation in periodontitis by changing the oral bacterial composition and inhibiting P. gingivalis in mice
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Author：
Han Wenrui, Jiao Yao, Mi Sicong, Han Shu, Xu Junji, Li Song, Liu Yi, Guo Lijia
IF：
2.9000
Publish_to：
BMC Oral Health
PMID：
37563632
Upregulation of girdin delays endothelial cell apoptosis via promoting engulfment of platelets
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Author：
Lan Yong, Dong Min, Li Yongjun, Diao Yongpeng, Chen Zuoguan, Wu Zhiyuan
IF：
2.8000
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
37548867
The combination of high glucose and LPS induces autophagy in bovine kidney epithelial cells via the Notch3/mTOR signaling pathway
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Author：
Cui Yaocheng, Guo Hongrui, Zhang Qin, Fang Jing, Xie Yue, Chen Shiyi, Ma Xiaoping, Gou Liping, Cui Hengmin, Geng Yi, Ye Gang, Zhong Zhijun, Ren Zhihua, Wang Ya, Deng Junliang, Yu Shuming, Cao Suizhong, Wang Zhisheng, Zuo Zhicai
IF：
2.7920
Publish_to：
BMC Veterinary Research
PMID：
35953831
Successful outcomes of intracytoplasmic sperm injection–embryo transfer using ejaculated spermatozoa from two Chinese asthenoteratozoospermic brothers with a compound heterozygous FSIP2 mutation
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Author：
Yuan Yuan, Wen-qing Xu, Zi-yi Chen, Ying Chen, Li Zhang, Liping Zheng, Tao Luo, Hou-yang Chen
IF：
2.7750
Publish_to：
ANDROLOGIA
PMID：
34935173
Inhibition of cell survival and invasion by Tanshinone IIA via FTH1: A key therapeutic target and biomarker in head and neck squamous cell carcinoma
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Author：
Wei Mao, Jian Ding, Yu Li, Ruofei Huang, Baoxin Wang
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
35837069
Efficacy of Enhanced Cytokine-Induced Killer Cells as an Adjuvant Immunotherapy for Renal Cell Carcinoma: Preclinical and Clinical Studies
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Author：
Yang Yang, Run-Qing Wang, Yi-Ming Zhong, Ming-Yao Meng, Yi-Yi Zhao, Li-Rong Yang, Lin Li, Zong-Liu Hou
IF：
2.6820
Publish_to：
Journal of Healthcare Engineering
PMID：
34540187
Sperm collection and characteristics analysis of the critically endangered Chinese pangolin (Manis pentadactyla)
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Author：
Li Yongzheng, Hua Yan, Xiang Zuofu, Xu Xuelin, Zhang Sunxiya, Wang Xianghe, An Fuyu, Ren Zhenyu, Wang Kai
IF：
2.6000
Publish_to：
Conservation Physiology
PMID：
38957843
Copolymer Micelle-administered Melatonin Ameliorates Hyperosmolarity-induced Ocular Surface Damage through Regulating PINK1-mediated Mitophagy
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Author：
Jing Xu, Peng Chen, Guangfen Zhao, Susu Wei, Qiqi Li, Chuanlong Guo, Qilong Cao, Xianggen Wu, Guohu Di
IF：
2.5550
Publish_to：
CURRENT EYE RESEARCH
PMID：
35179400
Role of Penicillin-Binding Protein 1b in the Biofilm Inhibitory Efficacy of Ceftazidime Against Escherichia coli
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Author：
Sun Fengjun, Sun Yixuan, Wang Yu, Yuan Qian, Xiong Lirong, Feng Wei, Xia Peiyuan
IF：
2.3430
Publish_to：
CURRENT MICROBIOLOGY
PMID：
35881255
Host miR-4301 promotes rotavirus replication via PPP1R3D in Caco-2 cells
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Author：
Lijun Song, Xiaotong Wang, Peicheng Zhong, Jiabo Chen, Zhi Tang, Xuemei Zhu, Yang Chen, Guiqin Dai, Yujing Zhou, Feng Li, Yuxuan Feng, Wenchang Zhao
IF：
2.3270
Publish_to：
JOURNAL OF MEDICAL VIROLOGY
PMID：
34260071
Evaluation of the antibacterial activity and mechanism of cannabigerol against drug-resistant Streptococcus iniae in vitro
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Author：
Wu Jianing, Wang Minmin, He Tingke, Li Xiaonan, Liu Bowen, Chen Fen, Geng Yi, Lai Weiming, Huang Xiaoli, Chen Defang, Ouyang Ping
IF：
2.3000
Publish_to：
ARCHIVES OF MICROBIOLOGY
PMID：
40146372
Kuwanon C inhibits proliferation and induction of apoptosis via the intrinsic pathway in MDA-MB231 and T47D breast cancer cells
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Author：
Peng Qian, Gangxiang Yuan, Chao Yang, Qi Zhang, Lin Chen, Ningjia He
IF：
2.1000
Publish_to：
STEROIDS
PMID：
38823755
MDA5 attenuate autophagy in chicken embryo fibroblasts infected with IBDV
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Author：
M. Yu, R. Li, M. Wan, J. Chen, X. Shen, G. Li, M. Ge, R. Zhang
IF：
2.0950
Publish_to：
BRITISH POULTRY SCIENCE
PMID：
34406094
STEAP3 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Regulating Fatty Acid and Lipid Droplet Synthesis
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Author：
Chenyang Yuan, Kaifeng Guan, Gaiping Zhang
IF：
2.0000
Publish_to：
Veterinary Sciences
PMID：
40005907
Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts
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Author：
Zhang Qing, Wang Maomao, Deng Xingwang, Zhao Dan, Zhao Fang, Xiao Jinli, Ma Jiaxiang, Pan Xiaoliang
IF：
1.1000
Publish_to：
Acta Cirurgica Brasileira
PMID：
37878984
技术问答
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注意：
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这个4%是戊二醛的浓度吗2024-10-08 16:44:49
您好，是的
稀释戊二醛为1%时，可否用PBS稀释，还是必须用PB稀释，两者对固定样本有差距吗?2023-07-04 22:01:03
您好，建议使用PB,PB可以保持渗透压稳定，同时，可以保证PH维持在7.2-7.4之间，又可以避免在冰冻的过程中盐类造成的额外的损伤。
有效期一个月是指开封后一个月吗?2022-10-14 14:16:27
您好，指的是按生产批次日期算而不是您打开使用的日期，收到后产品标签上会有EXP效期截止日期，在截止日期前使用。