Self-Adjuvanting Polyguanidine Nanovaccines for Cancer Immunotherapy
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Author:
Xuanbo Zhang, Kaiyuan Wang, Zhiqiang Zhao, Xinzhu Shan, Yuequan Wang, Zunyong Feng, Bingyu Li, Cong Luo, Xiaoyuan Chen, Jin Sun
Pyroptotic macrophages induce disruption of glutamate metabolism in periodontal ligament stem cells contributing to their compromised osteogenic potential
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Author:
Li-Juan Sun, Hong-Lei Qu, Xiao-Tao He, Bei-Min Tian, Rui-Xin Wu, Yuan Yin, Jie-Kang Zou, Hai-Hua Sun, Xuan Li, Fa-Ming Chen
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CELL PROLIFERATION
Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6
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Author:
Feng Zhiming, Hua Shiting, Li Wangan, Han Jianbang, Li Feng, Chen Haijia, Zhang Zhongfei, Xie Yu, Ouyang Qian, Zou Xiaoxiong, Liu Zhizheng, Li Cong, Huang Sixian, Lai Zelin, Cai Xiaolin, Cai Yingqian, Zou Yuxi, Tang Yanping, Jiang Xiaodan
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Cell Communication and Signaling
STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages
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Author:
Xin-yi Wu, Ya-jun Chen, Chang-an Liu, Jun-hua Gong, Xue-song Xu
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Oxidative Medicine and Cellular Longevity
PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis
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Author:
Shiuan Tien, Haoxiong Zhou, Qi Zhou, Huiling Liu, Bin Wu, Yunwei Guo
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LIVER INTERNATIONAL
Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway
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Author:
Liu Yao, Wei Yuanhuan, Wu Lanlan, Lin Xiaoping, Sun Ruifang, Chen Hengying, Shen Siwen, Deng Guifang
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Frontiers in Nutrition
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy
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Author:
Yu Yong-Wei, Que Jia-Qun, Liu Shuai, Huang Kai-Yu, Qian Lu, Weng Ying-Bei, Rong Fang-Ning, Wang Lei, Zhou Ying-Ying, Xue Yang-Jing, Ji Kang-Ting
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Frontiers in Cardiovascular Medicine
Entinostat Improves Motor Function and Neuronal Damage Via Downregulating NLRP3 Inflammasome Activation After Spinal Cord Injury
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Author:
Dai Chen, Liu Bin, Peng Bibo, Qu Bo, Lin Jiezhi, Peng Baogan, Li Duan-Ming
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Frontiers in Pharmacology
The aggravate role of exosomal circRNA11:120406118|12040782 on macrophage pyroptosis through miR-30b-5p/NLRP3 axis in silica-induced lung fibrosis
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Author:
Qi Zhang, Jiaqi Ban, Shuai Chang, Huiyan Qu, Jie Chen, Fangwei Liu
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INTERNATIONAL IMMUNOPHARMACOLOGY
Ameliorative effect of black raspberry anthocyanins on diabetes retinopathy by inhibiting axis protein tyrosine phosphatase 1B-endoplasmic reticulum stress
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Author:
Ting Xiao, Yuan Zhi, Fangfang Tian, Feilong Huang, Xingyan Cheng, Ai Wu, Ling Tao, Zhenghong Guo, Xiangchun Shen
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Journal of Functional Foods
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats
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Author:
Chaoqun Nie, Rentong Zou, Shuang Pan, Rong A, Yunan Gao, Hongxiao Yang, Juncai Bai, Shuiqing Xi, Xue Wang, Xiaojian Hong, Wei Yang
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway
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Author:
Meng-Yu Zhang, Ying-Xiao Jiang, Yi-Can Yang, Jian-Yu Liu, Chen Huo, Xiu-Li Ji, Yi-Qing Qu
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LIFE SCIENCES
VX-765 ameliorates CKD VSMC calcification by regulating STAT3 activation
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Author:
Yingjie Duan, Zhong Peng, Shuzhu Zhong, Peng Zhou, Hong Huang, Jianlong Li, Zhangxiu He
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EUROPEAN JOURNAL OF PHARMACOLOGY
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways
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Author:
Xiuhong Wang, Shibiao Chen, Lili Zhao, Xiaoyun Shi
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INTERNATIONAL IMMUNOPHARMACOLOGY
Oridonin attenuates liver ischemia–reperfusion injury by suppressing PKM2/NLRP3-mediated macrophage pyroptosis
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Author:
Xin-yi Wu, Min-jie Zhao, Wei Liao, Tao Liu, Jun-Yan Liu, Jun-hua Gong, Xing Lai, Xue-song Xu
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CELLULAR IMMUNOLOGY
Absent in melanoma 2-mediating M1 macrophages facilitate tumor rejection in renal carcinoma
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Author:
Dafei Chai, Zichun Zhang, Shang yuchen Shi, Dong Qiu, Chen Zhang, Gang Wang, Lin Fang, Huizhong Li, Hui Tian, Hailong Li, Junnian Zheng
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Translational Oncology
Zerumbone Reduces TLR2 Stimulation-Induced M1 Macrophage Polarization Pattern Via Upregulation of Nrf-2 Expression in Murine Macrophages
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Author:
Marwa Qadri, Zenat Khired, Reem Alaqi, Sandy Elsayed, Abdulaziz Alarifi, Rayan Ahmed, Hussain Alhamami, Amani Khardali, Walaa Hakami
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SAUDI PHARMACEUTICAL JOURNAL
Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium–glucose cotransporter 1
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Author:
Chai Qian, Meng Ziang, Lu Dexue, Zhang Ziying, Liu Meili, Wu Weihua
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MOLECULAR AND CELLULAR BIOCHEMISTRY
CircTHADA regulates endothelial cell pyroptosis in diabetic retinopathy through miR-494-3p/CASP1/GSDMD-N/IL-1β pathway
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Author:
Shuai He, Chufeng Gu, Chunren Meng, Chunyang Cai, Dongwei Lai, Qinghua Qiu
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EXPERIMENTAL CELL RESEARCH
Chrysin attenuates the NLRP3 inflammasome cascade to reduce synovitis and pain in KOA rats
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LncRNA MIAT promotes hypoxia-induced H9C2 cell pyroptosis via binding to SF1 to inhibit CGRP transcription
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EXPERIMENTAL PHYSIOLOGY
Silibinin ameliorates deoxycholic acid-induced pyroptosis in steatotic HepG2 cells by inhibiting NLRP3 inflammasome activation
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Author:
Meiqing Mai, Ya Wang, Mengliu Luo, Zhongxia Li, Di Wang, Yongdui Ruan, Honghui Guo
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Biochemistry and Biophysics Reports
Liraglutide ameliorates high glucose-induced vascular endothelial injury through TRIB3/NF-κB signaling pathway
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Author:
Shi Lili, Xu Yingying, Zhao Chao, Qu Guangjin, Hao Ming
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IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis
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