| 英文名称 |
Anti-Phospho-P38 MAPK(Thr180+Tyr182) Polyclonal Antibody |
| 中文名称 |
丝裂原活化蛋白激酶14抗体 |
| 宿主 |
Rabbit |
| 克隆类型 |
Polyclonal Antibody |
| 亚型 |
IgG |
| 预测交叉反应 |
Dog;Rabbit |
| 稀释比例 |
IHC 1:100-500. IF 1:100-500. |
| 靶标 |
Phospho-P38 MAPK(Thr180+Tyr182) |
| 别名 |
P38 MAPK(Phospho-Thr180); phospho-MAPK14(Thr180/Tyr182); MAPK14(phospho Thr180/Tyr182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A. |
| 背景说明 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases(MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Swiss Prot |
Q16539 |
| Gene ID |
1432 |
| 亚细胞定位 |
Cytoplasm Cell membrane |
| 免疫原 |
A synthetic peptide of human p38 MAPK around the phosphorylation site of Thr180/Tyr182: M(p-T)G(p-Y)VA |
| 理论分子量 |
42kDa |
| 纯化方法 |
Affinity purification |
| 储存液 |
0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol. |
| 储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
| 运输条件 |
冷冻运输 |
| 规格 |
50ul 100ul |
| 交叉反应 |
Human Mouse Rat |
| 应用 |
IHC IF |
| 研究领域 |
免疫学 表观遗传 |
| 单位 |
支 |
| 属性分类 |
修饰抗体 |
中文
英语
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