英文名称 |
Anti-SARS-CoV/SARS-CoV-2 Nucleocapsid Monoclonal Antibody |
宿主 |
Mouse |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG1 |
克隆号 |
2C12 |
稀释比例 |
WB 1:5000-8000. ELISA 1:5000-50000. |
靶标 |
SARS-CoV/SARS-CoV-2 Nucleocapsid |
别名 |
2019-nCoV Nucleocapsid;SARS-CoV-2 Nucleocapsid Protein;SARS-CoV-2 NP;2019-nCoV N;Coronavirus NP |
背景说明 |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Swiss Prot |
P0DTC9/P59595 |
Gene ID |
43740575/1489678 |
免疫原 |
Recombinant Protein |
理论分子量 |
46kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
储存条件 |
Store at -20℃. Avoid freeze/thaw cycles. |
规格 |
20ul 50ul 100ul |
交叉反应 |
SARS-CoV SARS-CoV-2 |
应用 |
WB Elisa |
单位 |
支 |
属性分类 |
病毒抗体 |