英文名称 |
Anti-MGMT Polyclonal Antibody |
中文名称 |
O6-甲基鸟嘌呤-DNA甲基转移酶抗体 |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
稀释比例 |
WB 1:500-1000. |
靶标 |
MGMT |
别名 |
6 O methylguanine DNA methyltransferase, Agat, AGT, AI267024, EC 2.1.1.63, Methylated DNA protein cysteine methyltransferase, Methylguanine DNA methyltransferase, MGC107020, MGMT: O-6 methylguanine DNA methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase, O-6 methylguanine DNA alkyltransferase, O-6-methylguanine-DNA methyltransferase, O6 methylguanine DNA methyltransferase, MGMT_HUMAN |
背景说明 |
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. |
Swiss Prot |
P16455 |
Gene ID |
4255 |
亚细胞定位 |
Nucleus |
免疫原 |
Recombinant protein of human MGMT |
Public Immunogen Range |
1-207aa |
理论分子量 |
22kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 0.03% Proclin300,50% glycerol,pH7.3. |
储存条件 |
Store at -20℃. Avoid freeze/thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human Mouse |
应用 |
WB |
单位 |
支 |
属性分类 |
其他抗体 |