英文名称 |
Anti-CASP3 Polyclonal Antibody |
中文名称 |
胱天蛋白酶3抗体 |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
预测交叉反应 |
Rabbit(86.7%);Chicken(90.9%);Dog(100%);Pig(100%);Monkey(100%);Chimpanzee(100%);Cat(100%);Hamster(93.3%) |
稀释比例 |
WB 1:2000-5000. IHC 1:25-100. |
靶标 |
CASP3 |
别名 |
CPP32,CPP32B,SCA-1,Caspase 3,SREBP cleavage activity 1,Cysteine protease CPP32 |
背景说明 |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
Swiss Prot |
P42574 |
Gene ID |
836 |
亚细胞定位 |
Cytoplasm |
免疫原 |
A synthetic peptide of Human CASP3 |
Public Immunogen Range |
185-235/277aa |
理论分子量 |
31kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
储存条件 |
Store at -20℃. Avoid freeze/thaw cycles. |
规格 |
20ul 50ul 100ul |
交叉反应 |
Human Rat Mouse |
应用 |
WB IHC |
研究领域 |
神经学 细胞生物学 发育生物学 信号传导 |
单位 |
支 |
属性分类 |
其他抗体 |