英文名称 |
Anti-S100B Polyclonal Antibody |
中文名称 |
S100钙结合蛋白B抗体 |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
稀释比例 |
WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg. |
靶标 |
S100B |
别名 |
NEF, Protein S100 B, Protein S100-B, S 100 calcium binding protein beta chain, S 100 protein beta chain, S 100 protein beta subunit, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 calcium binding protein B, S100 calcium binding protein beta (neural), S100 calcium binding protein beta chain, S100 calcium-binding protein B, S100 protein beta chain, S100B_HUMAN, S100beta, S100 β, S100-β, S100β |
背景说明 |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. |
Swiss Prot |
P04271 |
Gene ID |
6285 |
亚细胞定位 |
Cytoplasm Nucleus |
免疫原 |
Recombinant protein of human S100B |
Public Immunogen Range |
1-92aa |
理论分子量 |
11kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
储存条件 |
Store at -20℃. Avoid freeze/thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human Rat Mouse |
应用 |
WB IHC IF IP ELISA |
研究领域 |
干细胞 心血管 |
单位 |
支 |
属性分类 |
其他抗体 |