英文名称 |
Anti-ARRB1 Monoclonal Antibody |
中文名称 |
抑制素,β1抗体 |
宿主 |
Mouse |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG2b |
克隆号 |
6A1-D7-C9 |
稀释比例 |
WB 1:500-1000. |
靶标 |
ARRB1 |
别名 |
ARB1, ARR1, ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1 |
背景说明 |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]. |
Swiss Prot |
P49407 |
Gene ID |
408 |
亚细胞定位 |
Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Membrane Nucleus clathrin-coated pit pseudopodium |
免疫原 |
Recombinant protein of human ARRB1 |
理论分子量 |
47kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 0.02% sodium azide,0.5% BSA,50% glycerol,pH7.3. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human |
应用 |
WB |
研究领域 |
细胞生物学 信号传导 |
单位 |
支 |
属性分类 |
其他抗体 |