英文名称 |
Anti-PRMT6 Monoclonal Antibody |
中文名称 |
组蛋白精氨酸甲基转移酶6抗体 |
宿主 |
Mouse |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG1 |
克隆号 |
2C3-F1-G1 |
稀释比例 |
WB 1:500-1000. IHC 1:50-100. IF 1:50-200. ICC 1:50-200. |
靶标 |
PRMT6 |
别名 |
PRMT 6, PRMT6, ANM6_HUMAN, Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 6, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, HMT1 hnRNP methyltransferase like 6, HRMT1L6, prmt6, Protein arginine methyltransferase 6, Protein arginine N methyltransferase 6, Protein arginine N-methyltransferase 6 |
背景说明 |
PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication. |
Swiss Prot |
Q96LA8 |
Gene ID |
55170 |
亚细胞定位 |
Nucleus |
免疫原 |
Recombinant protein of human PRMT6 |
理论分子量 |
42kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 0.02% sodium azide,0.5% BSA,50% glycerol,pH7.3. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human |
应用 |
WB IHC ICC IF |
研究领域 |
表观遗传 神经学 |
单位 |
支 |
属性分类 |
其他抗体 |