英文名称 |
Anti-Wnt3 Monoclonal Antibody |
中文名称 |
Wnt3抗体 |
宿主 |
Mouse |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG1 |
克隆号 |
4F11-H1-F4 |
稀释比例 |
WB 1:500-1000. |
靶标 |
Wnt3 |
别名 |
Int 4, INT4, MGC131950, MGC138321, MGC138323, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, wingless type MMTV integration site family member 3, Wnt 3 proto oncogene protein, WNT 3 proto oncogene protein precursor, wnt3, WNT3_HUMAN |
背景说明 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. |
Swiss Prot |
P56703 |
Gene ID |
7473 |
亚细胞定位 |
Secreted extracellular matrix extracellular space |
免疫原 |
Recombinant protein of human Wnt3 |
理论分子量 |
40kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 0.02% sodium azide,0.5% BSA,50% glycerol,pH7.3. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human Mouse Rat |
应用 |
WB |
单位 |
支 |
属性分类 |
其他抗体 |