中文
英语
DCFH-DA
CAS:No.4091-99-0
英文名称:DCFH-DA
分子式:C24H16Cl2O7
分子量:487.29
储存条件:Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year
纯度:≥98%
产品简介
| CAS | No.4091-99-0 |
| 中文名称 | 2,7-二氯二氢代荧光黄二醋酸 |
| 英文名称 | DCFH-DA |
| 别名 | H2DCFDA;2，7-Dichlorodihydrofluorescein diacetate |
| 分子式 | C24H16Cl2O7 |
| 分子量 | 487.29 |
| 溶解性 | Soluble in DMSO |
| 纯度 | ≥98% |
| 外观(性状) | White to off-white Solid |
| 储存条件 | Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 685-843-8 |
| MDL | MFCD00128955 |
| SMILES | O=C(O)C1=CC=CC=C1C2C3=C(OC4=C2C=C(Cl)C(OC(C)=O)=C4)C=C(OC(C)=O)C(Cl)=C3 |
| 背景说明 | DCFH-DA是可渗透细胞,用于检测细胞内活性氧 (ROS) 的探针。不可用于切片或植物细胞。 |
| 规格 | 5mg 10mg 25mg 10mM*1mL in DMSO 50mg 100mg |
| 单位 | 瓶 |
DCFH-DA 本身没有荧光，可以自由穿过细胞膜，进入细胞内后，可以被细胞内的酯酶水解生成DCFH。而 DCFH 不能通透细胞膜，从而使探针很容易被装载到细胞内。细胞内的活性氧可以氧化无荧光的DCFH 生成有荧光的DCF 。检测DCF 的荧光就可以知道细胞内活性氧的水平。
操作步骤（仅供参考）：
一、制备探针：10mM（4.8729mg溶于1mL DMSO）
二、装载探针：
对于刺激时间较短（通常为2 小时以内）的细胞，先装载探针，后用活性氧阳性对照或自己感兴趣的药物刺激细胞。对于细胞刺激时间较长（通常为6 小时以上）的细胞，先用活性氧阳性对照或自己感兴趣的药物刺激细胞，后装载探针。
原位装载探针：本方法仅适用于贴壁培养细胞。按照1 ∶1000用无血清培养液稀释DCFH-DA，使终浓度为10μ mol/L。去除细胞培养液，加入适当体积稀释好的DCFH-DA。加入的体积以能充分盖住细胞为宜，通常对于六孔板的一个孔加入稀释好的DCFH-DA不少于1mL 。37℃细胞培养箱内孵育20 分钟。用无血清细胞培养液洗涤细胞三次，以充分去除未进入细胞内的DCFH-DA。通常活性氧阳性对照在刺激细胞20～30分钟后可以显著提高活性氧水平。
收集细胞后装载探针：按照1 ∶1000 用无血清培养液稀释DCFH-DA，使终浓度为10μmol/L。细胞收集后悬浮于稀释好的DCFH-DA中，细胞浓度为一百万至二千万/mL ，37℃细胞培养箱内孵育20分钟。每隔3 ～5 分钟颠倒混匀一下，使探针和细胞充分接触。用无血清细胞培养液洗涤细胞三次，以充分去除未进入细胞内的DCFH-DA。直接用活性氧阳性对照或自己感兴趣的药物刺激细胞，或把细胞等分成若干份后刺激细胞。通常活性氧阳性对照在刺激细胞20～30分钟后可以显著提高活性氧水平。
三、检测：
对于原位装载探针的样品可以用激光共聚焦显微镜直接观察，或收集细胞后用荧光分光光度计、荧光酶标仪或流式细胞仪检测。对于收集细胞后装载探针的样品可以用荧光分光光度计、荧光酶标仪或流式细胞仪检测，也可以用激光共聚焦显微镜直接观察。
四、参数设置
使用488nm 激发波长，525nm 发射波长，实时或逐时间点检测刺激前后荧光的强弱。DCF 的荧光光谱和FITC非常相似，可以用FITC的参数设置检测DCF 。
注意事项：
1. 探针装载后，一定要洗净残余的未进入细胞内的探针，否则会导致背景较高。
2. 探针装载完毕并洗净残余探针后，可以进行激发波长的扫描和发射波长的扫描，以确认探针的装载情况是否良好。DCF 的激发光谱和发射光谱请参考上图。
3. 尽量缩短探针装载后到测定所用的时间（刺激时间除外），以减少各种可能的误差。
4. 对于某些细胞，如果发现没有刺激的阴性对照细胞荧光也比较强，可以按照1 ∶2000～1 ∶5000稀释DCFH-DA，使装载探针时DCFH-DA的浓度为2～5μmol/L。探针装载的时间也可以根据情况在15～60分钟内适当进行调整。
5. 为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用本产品的应用案例（仅供参考）
In Vitro
Cell（HK-2 human kidney proximal tubular cells，20 μmol/L DCFH-DA，37℃ for 30 min）
Cell（vascular smooth muscle cells/VSMCs; 10 μM DCFH- DA; 37℃,30 min）
Cell（myoblasts；10 μM DCFH-DA，37°C，20 min）
Cell（PC12 cells；10 μM DCFH-DA ；37 °C，10 min）
Cell（4T1 cells，6 h later, the cells were washed with PBS for three times and stained with DCFH-DA for another 30 min.）
Cell（Plant somatic embryogenesis (SE)）
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
Li S, et al. Free Radic Biol Med. 2021 Jan;162:435-449.
Gao L, et al. Life Sci. 2020 May 1;248:117471.
Sun J, et al. Int J Biol Macromol. 2024 Apr;264(Pt 2):130663. doi: 10.1016/j.ijbiomac.2024.130663. Epub 2024 Mar 6.
暂无详情
Wang Z, et al.Sci Rep. 2020 Sep 24;10(1):15601.
Lu J, et al. Front Cell Dev Biol. 2023 Apr 11;11:1171506.
来源文献：Liu Y , et al.Materials Today Bio, 2024, 25.DOI:10.1016/j.mtbio.2024.100981.
Yuan J,et al.New Phytol. 2023 Oct;240(1):207-223. doi: 10.1111/nph.19120.
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Ye Qi, Shuangsong Ren, Junwei Ye, Yiming Tian, Guangyao Wang, Siqi Zhang, Linyao Du, Yachen Li, Ying Che, Guiling Ning
IF：
10.6330
Publish_to：
Acta Biomaterialia
PMID：
35235864
A nanozyme-functionalized bilayer hydrogel scaffold for modulating the inflammatory microenvironment to promote osteochondral regeneration
点击查看 >>
Author：
Hu Chuan, Huang Ruipeng, Xia Jiechao, Hu Xianjing, Xie Dingqi, jin Yang, Qi Weiming, Zhao Chengliang, Hu Zhijun
IF：
10.6000
Publish_to：
JOURNAL OF NANOBIOTECHNOLOGY
PMID：
39069607
Effective bioremediation of tobacco wastewater by microalgae at acidic pH for synergistic biomass and lipid accumulation
点击查看 >>
Author：
Ting-Bin Hao, Srinivasan Balamurugan, Zhong-Hong Zhang, Si-Fen Liu, Xiang Wang, Da-Wei Li, Wei-Dong Yang, Hong-Ye Li
IF：
10.5880
Publish_to：
JOURNAL OF HAZARDOUS MATERIALS
PMID：
34865896
“All-in-one” metal polyphenol network nanocapsules integrated microneedle patches for lipophagy fueled ferroptosis-mediated multimodal therapy
点击查看 >>
Author：
Wenhao Wang, Ziqiao Zhong, Siyuan Peng, Jintao Fu, Minglong Chen, Tianqun Lang, Xiao Yue, Yanping Fu, Jingyu He, Yuzhen Jin, Ying Huang, Chuanbin Wu, Zhengwei Huang, Xin Pan
IF：
10.5000
Publish_to：
JOURNAL OF CONTROLLED RELEASE
PMID：
39074587
A novel targeted co-delivery nanosystem for enhanced ovarian cancer treatment via multidrug resistance reversion and mTOR-mediated signaling pathway
点击查看 >>
Author：
Wang Xueqin, Xiong Tiandi, Cui Miao, Li Na, Li Qin, Zhu Li, Duan Shaofeng, Wang Yunlong, Guo Yuqi
IF：
10.4350
Publish_to：
JOURNAL OF NANOBIOTECHNOLOGY
PMID：
34949180
Carbon Dots from Lycium barbarum Attenuate Radiation-Induced Bone Injury by Inhibiting Senescence via METTL3/Clip3 in an m6A-Dependent Manner
点击查看 >>
Author：
Zhiyong Guo, Zilin Wang, Yige Liu, Hao Wu, Qiaoyu Zhang, Jing Han, Jiannan Liu, Chenping Zhang
IF：
10.3830
Publish_to：
ACS Applied Materials & Interfaces
PMID：
37088945
Quaternary ammonium biocides promote conjugative transfer of antibiotic resistance gene in structure- and species-dependent manner
点击查看 >>
Author：
Qin Hu, Lilan Zhang, Rui Yang, Jialin Tang, Guoliang Dong
IF：
10.3000
Publish_to：
ENVIRONMENT INTERNATIONAL
PMID：
38878503
A triple-enhanced chemodynamic approach based on glucosepowered hybrid nanoreactors for effective bacteria killing
点击查看 >>
Author：
Fu J ;Zhou Y ;Liu T ;et al
IF：
10.2690
Publish_to：
Nano research
PMID：
Spontaneous formation of MXene-oxidized sono/chemo-dynamic sonosensitizer/nanocatalyst for antibacteria and bone-tissue regeneration
点击查看 >>
Author：
Yu Yang, Sun Houyi, Lu Qunshan, Sun Junyuan, Zhang Pengfei, Zeng Linran, Vasilev Krasimir, Zhao Yunpeng, Chen Yu, Liu Peilai
IF：
10.2000
Publish_to：
JOURNAL OF NANOBIOTECHNOLOGY
PMID：
37316836
Multi-antitumor therapy and synchronous imaging monitoring based on exosome
点击查看 >>
Author：
Qian Ruijie, Jing Boping, Jiang Dawei, Gai Yongkang, Zhu Ziyang, Huang Xiaojuan, Gao Yu, Lan Xiaoli, An Rui
IF：
10.0570
Publish_to：
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
PMID：
35091755
Conformation Dependent Architectures of Assembled Antimicrobial Peptides with Enhanced Antimicrobial Ability
点击查看 >>
Author：
Xinmiao Lan, Jie Zhong, Regina Huang, Yuhan Liu, Xiaowei Ma, Xuan Li, Dan Zhao, Guangchao Qing, Yuxuan Zhang, Lu Liu, Jinjin Wang, Xu Ma, Ting Luo, Weisheng Guo, Yuji Wang, Li-Li Li, Yu-Xiong Su, Xing-Jie Liang
IF：
10.0000
Publish_to：
Advanced Healthcare Materials
PMID：
37540835
Acidity-responsive nanocages as robust reactive oxygen species generators with butterfly effects for maximizing oxidative damage and enhancing cancer therapy
点击查看 >>
Author：
Xingru Zhao, Xingyi Wan, Tian Huang, Shuncheng Yao, Shaobo Wang, Yiming Ding, Yunchao Zhao, Zhou Li, Linlin Li
IF：
9.9650
Publish_to：
JOURNAL OF COLLOID AND INTERFACE SCIENCE
PMID：
35339963
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing
点击查看 >>
Author：
Shen Guo, Minghao Yao, Dan Zhang, Yuanmeng He, Rong Chang, Yikun Ren, Fangxia Guan
IF：
9.9330
Publish_to：
Advanced Healthcare Materials
PMID：
34787374
Photothermal-promoted O2/OH generation of gold nanotetrapod @ platinum nano-islands for enhanced catalytic/photodynamic therapy
点击查看 >>
Author：
Gangwan Zhang, Ran Hao, Jiahe Zhang, Di Wu, Leyong Zeng
IF：
9.9000
Publish_to：
JOURNAL OF COLLOID AND INTERFACE SCIENCE
PMID：
38109817
Sodium p-perfluorous nonenoxybenzene sulfonate induces ROS-mediated necroptosis by directly targeting catalase in HepG2 cells
点击查看 >>
Author：
Yiyuan Ye, Bingyan Liu, Zijian Wang, Ling Liu, Qiu Zhang, Qingzhu Zhang, Wei Jiang
IF：
9.8000
Publish_to：
SCIENCE OF THE TOTAL ENVIRONMENT
PMID：
37949132
Tumor Cell Targeting and Responsive Nanoplatform for Multimodal-Imaging Guided Chemodynamic/Photodynamic/Photothermal Therapy toward Triple Negative Breast Cancer
点击查看 >>
Author：
Lihong Li, Jiaojiao Li, Rongrong Hu, Xinyu Zhang, Lei Ding, Guodong Ren, Wen Liu, Haojiang Wang, Bin Wang, Chengwu Zhang, Haipeng Diao
IF：
9.5000
Publish_to：
ACS Applied Materials & Interfaces
PMID：
37261936
Carbon dots induce pathological damage to the intestine via causing intestinal flora dysbiosis and intestinal inflammation
点击查看 >>
Author：
Jia Mengmeng, Yi Bingcheng, Chen Xian, Xu Yongzhi, Xu Xinkai, Wu Zhaoxu, Ji Jing, Tang Jinglong, Yu Dianke, Zheng Yuxin, Zhou Qihui, Zhao Yanjie
IF：
9.4290
Publish_to：
JOURNAL OF NANOBIOTECHNOLOGY
PMID：
37231475
GhRCD1 regulates cotton somatic embryogenesis by modulating the GhMYC3–GhMYB44–GhLBD18 transcriptional cascade
点击查看 >>
Author：
Jiachen Yuan, Xingxing Liu, Hang Zhao, Ye Wang, Xi Wei, Peng Wang, Jingjing Zhan, Lisen Liu, Fuguang Li, Xiaoyang Ge
IF：
9.4000
Publish_to：
NEW PHYTOLOGIST
PMID：
37434324
Integrating network analysis and experimental validation to reveal the mitophagy-associated mechanism of Yiqi Huoxue (YQHX) prescription in the treatment of myocardial ischemia/reperfusion injury
点击查看 >>
Author：
Mingtai Chen, Guofu Zhong, Mengnan Liu, Hao He, Jie Zhou, Jianping Chen, Mingsheng Zhang, Qiang Liu, Guangdong Tong, Jienan Luan, Hua Zhou
IF：
9.3000
Publish_to：
PHARMACOLOGICAL RESEARCH
PMID：
36736970
Identification, in silico selection, and mechanism study of novel antioxidant peptides derived from the rice bran protein hydrolysates
点击查看 >>
Author：
Li-kun Ren, Jing Fan, Yang Yang, Xiao-fei Liu, Bing Wang, Xin Bian, Dang-feng Wang, Yue Xu, Bao-xiang Liu, Peng-yu Zhu, Na Zhang
IF：
9.2310
Publish_to：
FOOD CHEMISTRY
PMID：
36549163
Bioresponsive Nanoarchitectonics-Integrated Microneedles for Amplified Chemo-Photodynamic Therapy against Acne Vulgaris
点击查看 >>
Author：
Ting Wen, Zhiyuan Lin, Yiting Zhao, Yixian Zhou, Boyi Niu, Chaonan Shi, Chao Lu, Xinguo Wen, Minmin Zhang, Guilan Quan, Chuanbin Wu, Xin Pan
IF：
9.2290
Publish_to：
ACS Applied Materials & Interfaces
PMID：
34613687
Targeted inhibition of the PI3K/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer
点击查看 >>
Author：
Li Xiao-Qian, Cheng Xiao-Ju, Wu Jie, Wu Kai-Feng, Liu Tie
IF：
9.2000
Publish_to：
CELLULAR & MOLECULAR BIOLOGY LETTERS
PMID：
38649803
When Combined with Pentamidine,Originally Ineffective Linezolid Becomes Active in Carbapenem-Resistant Enterobacteriaceae
点击查看 >>
Author：
Miran Tang, Changrui Qian, Xiaotuan Zhang, Yan Liu, Wei Pan, Zhuocheng Yao, Weiliang Zeng, Chunquan Xu, Tieli Zhou
IF：
9.0430
Publish_to：
Microbiology Spectrum
PMID：
37125928
HSPB1 facilitates chemoresistance through inhibiting ferroptotic cancer cell death and regulating NF-κB signaling pathway in breast cancer
点击查看 >>
Author：
Liang Yiran, Wang Yajie, Zhang Yan, Ye Fangzhou, Luo Dan, Li Yaming, Jin Yuhan, Han Dianwen, Wang Zekun, Chen Bing, Zhao Wenjing, Wang Lijuan, Chen Xi, Ma Tingting, Kong Xiaoli, Yang Qifeng
IF：
9.0000
Publish_to：
Cell Death & Disease
PMID：
37454220
Elevated temperature magnifies the acute and chronic toxicity of clothianidin to Eisenia fetida
点击查看 >>
Author：
Yingnan Wang, Jiatao Shen, Hongbin Lang, Fan Shen, Luqing Zhang, Hua Fang, Yunlong Yu
IF：
8.9000
Publish_to：
ENVIRONMENTAL POLLUTION
PMID：
38795815
lncRNA-encoded pep-AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin
点击查看 >>
Author：
Xinyi Wang, Haiyang Zhang, Shengjie Yin, Yuchong Yang, Haiou Yang, Jiayu Yang, Zhengyang Zhou, Shuang Li, Guoguang Ying, Yi Ba
IF：
8.8070
Publish_to：
EMBO REPORTS
PMID：
34779552
Conceptual functional-by-design optimisation of the antioxidant capacity of trans-resveratrol,quercetin,and chlorogenic acid: application in a functional tea
点击查看 >>
Author：
Hazel Corrigan, Aoife Dunne, Niamh Purcell, Yuyang Guo, Kai Wang, Hongzhuan Xuan, Daniel Granato
IF：
8.8000
Publish_to：
FOOD CHEMISTRY
PMID：
37463557
Primitive genotypic characteristics in umbilical cord neutrophils identified by single-cell transcriptome profiling and functional prediction.
点击查看 >>
Author：
Yi Chen, Jiamin Huang, Zaiwen Guo, Zhechen Zhu, Yiming Shao, Linbin Li, Yunxi Yang, Yanzhen Yu, Lu Liu, Bingwei Sun
IF：
8.7860
Publish_to：
Frontiers in Immunology
PMID：
36105817
Natural hydrogen gas and engineered microalgae prevent acute lung injury in sepsis
点击查看 >>
Author：
Yuanlin Wang, Qingqing Han, Lingling Liu, Shuai Wang, Yongfa Li, Zhanying Qian, Yi Jiang, Yonghao Yu
IF：
8.7000
Publish_to：
Materials Today Bio
PMID：
39328786
Fabrication, characterization, and bioactivity of self-assembled carrier-free colloidal dispersions from Citrus × Limon ‘Rosso’ essential oil and tea polyphenols
点击查看 >>
Author：
Fangying Cheng, Mianhong Chen, Zhihao Duan, Ying Zou, Yunxia He, Fanke Zeng, Yuan Yuan, Tiaokun Fu, Hao Tu, Ruyi Li, Jihua Li, Wei Zhou
IF：
8.5000
Publish_to：
FOOD CHEMISTRY
PMID：
38905825
Nickel nanoparticles exert cytotoxic effects on trophoblast HTR-8/SVneo cells possibly via Nrf2/MAPK/caspase 3 pathway
点击查看 >>
Author：
Ting Li, Zhou Li, Jianfei Fu, Chunlan Tang, Liya Liu, Jin Xu, Jinshun Zhao, Zhen Li
IF：
8.4310
Publish_to：
ENVIRONMENTAL RESEARCH
PMID：
36103928
Regulation of NCOA4-mediated iron recycling ameliorates paraquat-induced lung injury by inhibiting ferroptosis
点击查看 >>
Author：
Du Jing, Yu Lingyan, Yang Xinyi, Shao Fangchun, Xia Jun, Jin Weidong, Zhang Yinhao, Lei Guojie, Wang Ying, Li Yanchun, Zhang Jun
IF：
8.4000
Publish_to：
Cell Communication and Signaling
PMID：
38388414
Aggregation-Induced Emission CN-Based Nanoparticles to Alleviate Hypoxic Liver Fibrosis via Triggering HSC Ferroptosis and Enhancing Photodynamic Therapy
点击查看 >>
Author：
Ming-Xuan Liu, Yu-Ting Cai, Ruo-Jia Wang, Peng-Fei Zhu, Yan-Chao Liu, Hao Sun, Yong Ling, Wei-Zhong Zhu, Jing Chen, Xiao-Ling Zhang
IF：
8.3000
Publish_to：
ACS Applied Materials & Interfaces
PMID：
38888460
Chitosan-based food-grade Pickering emulsion loading with Rosa roxburghii extract against precancerous lesions of gastric carcinoma
点击查看 >>
Author：
Sibu Wang, Junyu Wang, Jun Zhang, Xingjie Wu, Qianqian Guo, Yu'e Wang, Ling Tao, Xiangchun Shen, Ying Chen
IF：
8.2000
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
37981272
autophagy inhibitor 1oaded mesoporous agnps sio2 nanop1atfonn for synergistica11y enhanced g1ioma radiotherapy
点击查看 >>
Author：
haowu;yuegu
IF：
8.1000
Publish_to：
SCIENCE CHINA Materials
PMID：
PDTAC: Targeted Photodegradation of GPX4 Triggers Ferroptosis and Potent Antitumor Immunity
点击查看 >>
Author：
Sijin Liu, Xi Zhao, Sufang Shui, Biao Wang, Yingxian Cui, Suwei Dong, Tairan Yuwen, Guoquan Liu
IF：
8.0390
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
PMID：
36066386
Ulvan inhibits α-synuclein fibrillation and disrupts the mature fibrils: In vitro and in vivo studies
点击查看 >>
Author：
Wenqian Wang, Xinyu Wang, Wen Gao, Zhan Cui, Huitu Zhang, Fuping Lu, Fufeng Liu
IF：
8.0250
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
35561861
Biodegradable Persistent ROS-Generating Nanosonosensitizers for Enhanced Synergistic Cancer Therapy by Inducing Cascaded Oxidative Stress
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Author：
Yue Chen, Tong Ding, Zhengzheng Qian, Zerui Ma, Liming Zhou, Zhiling Li, Runkai Lv, Yinghui Xu, Yingjie Xu, Linhui Hao, Chen Zhu, Xikuang Yao, Wenying Yu, Wenpei Fan
IF：
8.0000
Publish_to：
Nanoscale Horizons
PMID：
39295580
Effects and mechanisms of frehmaglutin D and rehmaionoside C improve LPS-induced acute kidney injury through the estrogen receptor-mediated TLR4 pathway in vivo and in vitro
点击查看 >>
Author：
Meng Liu, Pengli Guo, Mengnan Zeng, Yuhan Zhang, Jufang Jia, Yanling Liu, Xu Chen, Haixue Kuang, Weisheng Feng, Xiaoke Zheng
IF：
7.9000
Publish_to：
PHYTOMEDICINE
PMID：
37980806
ROS-mediated liposomal dexamethasone: a new FA-targeted nanoformulation to combat rheumatoid arthritis via inhibiting iRhom2/TNF-α/BAFF pathways
点击查看 >>
Author：
Yanqin Song, Muhammad Ismail, Qi Shan, Jianing Zhao, Yanping Zhu, Leiming Zhang, Yuan Du, Longbing Ling
IF：
7.7900
Publish_to：
Nanoscale
PMID：
34846489
Carrageenan/polyvinyl alcohol composite film reinforced with spermidine carbon dots: An active packaging material with dual-mode antibacterial activity
点击查看 >>
Author：
Fan Li, Shuangshuang Zhu, Yuhan Du, Taotao Zhe, Kaixuan Ma, Mengru Liu, Li Wang
IF：
7.7000
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
38574934
Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling
点击查看 >>
Author：
Kang Wang, Yan Tang, Xiu Wu, Hongmin Liang, Daiwen Chen, Bing Yu, Jun He, Xiangbing Mao, Zhiqing Huang, Hui Yan, Aimin Wu, Yuheng Luo, Ping Zheng, Jie Yu, Huifen Wang, Junqiu Luo
IF：
7.6750
Publish_to：
Antioxidants
PMID：
36139913
7-Ketocholesterol Induces Oxiapoptophagy and Inhibits Osteogenic Differentiation in MC3T3-E1 Cells
点击查看 >>
Author：
Jing Ouyang, Yaosheng Xiao, Qun Ren, Jishang Huang, Qingluo Zhou, Shanshan Zhang, Linfu Li, Weimei Shi, Zhixi Chen, Longhuo Wu
IF：
7.6660
Publish_to：
Cells
PMID：
36139457
Nano-sized microplastics exposure induces skin cell senescence via triggering the mitochondrial localization of GSDMD
点击查看 >>
Author：
Wang han, Jiayue Cui, Gao Sun, Xiao Miao, Zhang Pufang, Li nannan
IF：
7.6000
Publish_to：
ENVIRONMENTAL POLLUTION
PMID：
38552769
Combined photothermal–photodynamic therapy by indocyanine green loaded polydopamine nanoparticles enhances anti-mammary gland tumor efficacy
点击查看 >>
Author：
Xu Liu, Na Xu, Ximing Pu, Juan Wang, Xiaoming Liao, Zhongbing Huang, Guangfu Yin
IF：
7.5710
Publish_to：
Journal of Materials Chemistry B
PMID：
35642529
Neutrophil Extracellular Traps Promote Aberrant Macrophages Activation in Behçet’s Disease
点击查看 >>
Author：
Li Lu, Yu Xin, Liu Jinjing, Wang Zhimian, Li Chaoran, Shi Jing, Sun Luxi, Liu Yi, Zhang Fengchun, Chen Hua, Zheng Wenjie
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
33633724
Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth
点击查看 >>
Author：
Zhang Yizheng, Zhang Chuchu, Li Jiehan, Jiang Meimei, Guo Shuning, Yang Ge, Zhang Lingling, Wang Feng, Yi Shiqi, Wang Jiangang, Fu Yang, Zhang Yingjie
IF：
7.5250
Publish_to：
Cell Communication and Signaling
PMID：
35715817
MiR-27a-5p regulates acrylamide-induced mitochondrial dysfunction and intrinsic apoptosis via targeting Btf3 in rats
点击查看 >>
Author：
Lujia Zhang, Li Dong, Liuqing Yang, Yinghua Luo, Fang Chen
IF：
7.5140
Publish_to：
FOOD CHEMISTRY
PMID：
34416489
Pipecolic acid mitigates ferroptosis in diabetic retinopathy by regulating GPX4-YAP signaling
点击查看 >>
Author：
Liying Luo, Yuying Cai, Yanyun Jiang, Yingying Gong, Chunyang Cai, Dongwei Lai, Xiao Jin, Zhiqiang Guan, Qinghua Qiu
IF：
7.5000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
37984309
Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail
点击查看 >>
Author：
Hao Wu, Yu Wang, Jingjian Huang, Yaolei Li, Zhijian Lin, Bing Zhang
IF：
7.4190
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
36587556
Modular DNA Tetrahedron Nanomachine-Guided Dual-Responsive Hybridization Chain Reactions for Discernible Bivariate Assay and Cell Imaging
点击查看 >>
Author：
Chunli Yang, Yanan Shi, Yuqing Zhang, Jiayang He, Mengdie Li, Weixiang Huang, Ruo Yuan, Wenju Xu
IF：
7.4000
Publish_to：
ANALYTICAL CHEMISTRY
PMID：
37365899
ROS-responsive nanoparticle-mediated delivery of CYP2J2 gene for therapeutic angiogenesis in severe hindlimb ischemia
点击查看 >>
Author：
Liang Gui, Youlu Chen, Yongpeng Diao, Zuoguan Chen, Jianwei Duan, Xiaoyu Liang, Huiyang Li, Kaijing Liu, Yuqing Miao, Qing Gao, Zhichao Li, Jing Yang, Yongjun Li
IF：
7.3480
Publish_to：
Materials Today Bio
PMID：
34988419
Cellular defense system-destroying nanoparticles as a platform for enhanced chemotherapy against drug-resistant cancer
点击查看 >>
Author：
Boyi Niu, Kaixin Liao, Yixian Zhou, Ting Wen, Guilan Quan, Chuanbin Wu, Xin Pan
IF：
7.3280
Publish_to：
Materials Science & Engineering C-Materials for Biological Applications
PMID：
34857280
Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway
点击查看 >>
Author：
Yujie Li, Chengcheng Shen, Xin Zhou, Jianghe Zhang, Xiaoyue Lai, Yiming Zhang
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
35300173
Hypomethylated interferon regulatory factor 8 recruits activating protein-2α to attenuate porcine epidemic diarrhea virus infection in porcine jejunum
点击查看 >>
Author：
Qiufang Zong, Huan Qu, Xianrui Zheng, Haifei Wang, Shenglong Wu, Zongjun Yin, Wenbin Bao
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
37593742
Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria
点击查看 >>
Author：
Wang Deping, Li Bowen, Wang Shuchao, Hao Yingjian, Wang Hua, Sun Wei, Cao Jimin, Zhou Xin, Zheng Bin
IF：
7.2000
Publish_to：
npj Regenerative Medicine
PMID：
37567914
Analysis of the roles of the Notch1 signalling pathway in modulating deoxynivalenol cytotoxicity
点击查看 >>
Author：
Yeyi Xiao, Jie Wang, Jingneng Wang, Haifei Wang, Shenglong Wu, Wenbin Bao
IF：
7.1290
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
36270035
GSH exhaustion via inhibition of xCT-GSH-GPX4 pathway synergistically enhanced DSF/Cu-induced cuproptosis in myelodysplastic syndromes
点击查看 >>
Author：
Huanjuan Li, Yanchun Li, Yanhua Yu, Xueying Ren, Chen Yang, Weidong Jin, Keyi Li, Yi Zhou, Cuiyun Wu, Yuhuan Shen, Wanye Hu, Yingchao Liu, Lingyan Yu, Xiangmin Tong, Jing Du, Ying Wang
IF：
7.1000
Publish_to：
FREE RADICAL BIOLOGY AND MEDICINE
PMID：
38866192
Discovery of a novel piperlongumine analogue as a microtubule polymerization inhibitor with potent anti-angiogenic and anti-metastatic efficacy
点击查看 >>
Author：
Jinling Qin, Hongliang Li, Xuan Wang, Yixin Zhang, Yongtao Duan, Yongfang Yao, Hua Yang, Moran Sun
IF：
7.0880
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
36162214
Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway
点击查看 >>
Author：
Minghui Dong, Ziying Yang, Qian Gao, Qingyuan Deng, Le Li, Hongmei Chen
IF：
7.0000
Publish_to：
Antioxidants
PMID：
38671893
Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ signaling pathway
点击查看 >>
Author：
He Simeng, Shi Jia, Liu Wenming, Du Shihan, Zhang Yuan, Gong Lirong, Dong Shuan, Li Xiangyun, Gao Qiaoying, Yang Jing, Yu Jianbo
IF：
6.9860
Publish_to：
INFLAMMATION RESEARCH
PMID：
35816227
Hyaluronic Acid-Enwrapped Polyoxometalate Complex for Synergistic Near Infrared-II Photothermal/Chemo-Therapy and Chemodynamic Therapy
点击查看 >>
Author：
Xueping Kong, Qiuyan Chen, Guofeng Wan, Yimeng Yang, Huimei Yu, Bao Li, Lixin Wu
IF：
6.9780
Publish_to：
BIOMACROMOLECULES
PMID：
36001455
A combined evaluation of the characteristics and antibiotic resistance induction potential of antibiotic wastewater during the treatment process
点击查看 >>
Author：
Sun Miao, Yanyan Zhang, Cong Men, Yiou Mao, Jiane Zuo
IF：
6.9000
Publish_to：
Journal of Environmental Sciences
PMID：
38135426
UCPs/Zn2GeO4:Mn2+/g-C3N4 heterojunction engineered injectable thermosensitive hydrogel for oxygen independent breast cancer neoadjuvant photodynamic therapy
点击查看 >>
Author：
Linchao Zhang, Manli Yang, Yishun Ji, Kefeng Xiao, Jinsheng Shi, Lili Wang
IF：
6.8430
Publish_to：
Biomaterials Science
PMID：
33491011
Triptolide inhibits oxidative stress and inflammation via the microRNA-155-5p/brain-derived neurotrophic factor to reduce podocyte injury in mice with diabetic nephropathy
点击查看 >>
Author：
Jian Gao, Zheng Liang, Fei Zhao, Xiaojing Liu, Ning Ma
IF：
6.8320
Publish_to：
Bioengineered
PMID：
35603354
All-in-one device for mapping the interactive effects of photodynamic therapy dosimetry in tumor gaseous microenvironment
点击查看 >>
Author：
Shu Zhang, Yuewu Li, Rui Dong, Weitao Li, Zhiyu Qian, Yamin Yang
IF：
6.8140
Publish_to：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
PMID：
36608400
Toxicological impacts of microplastics on virulence, reproduction and physiological process of entomopathogenic nematodes
点击查看 >>
Author：
Mingge Li, Bingjun Ha, Yuchen Li, Klaas Vrieling, Zhen Fu, Qilin Yu, Sergio Rasmann, Xianqin Wei, Weibin Ruan
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38422790
Arabinogalactan derived from Lycium barbarum fruit inhibits cancer cell growth via cell cycle arrest and apoptosis
点击查看 >>
Author：
Gong G; Liu Q; Deng Y; Dang T; Dai W; Liu T; Liu Y
IF：
6.7820
Publish_to：
Int J Biol Macromol
PMID：
31991207
Glucagon-like peptide-1 receptor activation by liraglutide promotes breast cancer through NOX4/ROS/VEGF pathway
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Author：
Zhan-zhao Liu, Xian-xian Duan, Meng-ci Yuan, Jing Yu, Xiao Hu, Xiao Han, Lan Lan, Bo-wei Liu, Yue Wang, Jun-fang Qin
IF：
6.7800
Publish_to：
LIFE SCIENCES
PMID：
35124000
Mesoporous polydopamine delivery system for intelligent drug release and photothermal-enhanced chemodynamic therapy using MnO2 as gatekeeper
点击查看 >>
Author：
Wang Zhaoyang, Li Zekai, Shi Yuehua, Zeng Leyong
IF：
6.7000
Publish_to：
Regenerative Biomaterials
PMID：
37936892
Total flavonoids of Selaginella tamariscina (P.Beauv.) Spring ameliorates doxorubicin-induced cardiotoxicity by modulating mitochondrial dysfunction and endoplasmic reticulum stress via activating MFN2/PERK
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Author：
Liyuan Gao, Peipei Yuan, Yaxin Wei, Yang Fu, Ying Hou, Panying Li, Yi Chen, Yuan Ruan, Ning Zhou, Xiaoke Zheng, Weisheng Feng
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
35358932
Hollow silver–gold alloy nanoparticles for enhanced photothermal/photodynamic synergetic therapy against bacterial infection and acceleration of wound healing
点击查看 >>
Author：
Shanshan Lin, Hui Chen, Rui Wang, Tongmeng Jiang, Rui Wang, Fabiao Yu
IF：
6.6000
Publish_to：
Biomaterials Science
PMID：
37293878
Antioxidative, cytoprotective and whitening activities of fragrant pear fruits at different growth stages
点击查看 >>
Author：
Hui Jiang, Fei Wu, Xi Jiang, Yun-Feng Pu, Li-Rong Shen, Cui-Yun Wu, Hong-Jin Bai
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
36245497
Enzymatic Hydrolysis of Broken Rice Protein: Antioxidant Activities by Chemical and Cellular Antioxidant Methods
点击查看 >>
Author：
Ren Likun, Fan Jing, Yang Yang, Xu Yue, Chen Fenglian, Bian Xin, Xing Tonglin, Liu Linlin, Yu Dehui, Zhang Na
IF：
6.5760
Publish_to：
Frontiers in Nutrition
PMID：
34957188
Zebrafish Model for Screening Antiatherosclerosis Drugs
点击查看 >>
Author：
Jichun Han, Rui Zhang, Xiaofeng Zhang, Jing Dong, Minghan Chen, Yumin Pan, Zixian Liao, Min Zhong, Jingwen He, Feiqiang Wang, Yunyun Yue, Jing Shang
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
34257830
Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy
点击查看 >>
Author：
LiS;ZhengL;ZhangJ;LiuX;WuZ
IF：
6.5250
Publish_to：
Free Radic Biol Med
PMID：
33152439
Surface saturation of drug-loaded hollow manganese dioxide nanoparticles with human serum albumin for treating rheumatoid arthritis
点击查看 >>
Author：
Ming Jia, Wei Ren, Minrui Wang, Yan Liu, Chenglong Wang, Zongquan Zhang, Maochang Xu, Nianhui Ding, Chunhong Li, Hong Yang
IF：
6.5000
Publish_to：
DRUG DELIVERY
PMID：
39044468
Integrated assessment of the clinical and biological value of ferroptosis-related genes in multiple myeloma
点击查看 >>
Author：
Fu Bibo, Shao Ruonan, Wang Huizhong, Chen Guanjun, Bai Shenrui, Wang Hua
IF：
6.4290
Publish_to：
Cancer Cell International
PMID：
36274128
A versatile and low-toxicity material for photothermal therapy in deeper tissues
点击查看 >>
Author：
Liguo Jin, Yinyin Wang, Huan Ouyang, Yu Liu, Zhenling Zhu, Shuhua Wang, Hongbo Xin, Xiaolei Wang
IF：
6.3310
Publish_to：
Journal of Materials Chemistry B
PMID：
34318782
Protective effects of chlorogenic acid on the meat quality of oxidatively stressed broilers revealed by integrated metabolomics and antioxidant analysis
点击查看 >>
Author：
Kai Zhang, Xuemin Li, Jinshan Zhao, Yang Wang, Xiaojing Hao, Kaidong Liu, Huawei Liu
IF：
6.3170
Publish_to：
Food & Function
PMID：
35133368
Dietary ferulic acid supplementation enhances antioxidant capacity and alleviates hepatocyte pyroptosis in diquat challenged piglets
点击查看 >>
Author：
Luo Junqiu, Wu Xiu, Chen Daiwen, Yu Bing, He Jun
IF：
6.3000
Publish_to：
Journal of Animal Science and Biotechnology
PMID：
39370514
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation
点击查看 >>
Author：
Dian-Long Liu, Si-Jia Liu, Su-Qin Hu, Yu-Cai Chen, Jian Guo
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36232461
Chitosan Thermosensitive Hydrogel Based on DNA Damage Repair Inhibition and Mild Photothermal Therapy for Enhanced Antitumor Treatment
点击查看 >>
Author：
Yang Yu, Teng Wang, Xin Meng, Tianze Jiang, Xia Zhao
IF：
6.2000
Publish_to：
BIOMACROMOLECULES
PMID：
37506051
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes
点击查看 >>
Author：
Xiong Liang, Huang Jinyu, Wang Sihui, Yuan Qiong, Yang Dongmei, Zheng Zuobing, Wu Yangna, Wu Chunmei, Gao Yanfang, Zou Lijun, Hu Gonghua
IF：
6.1680
Publish_to：
ARCHIVES OF TOXICOLOGY
PMID：
35088107
Honokiol induces ferroptosis in colon cancer cells by regulating GPX4 activity
点击查看 >>
Author：
Cao Guo, Ping Liu, Ganlu Deng, Ying Han, Yihong Chen, Changjing Cai, Hong Shen, Gongping Deng, Shan Zeng
IF：
6.1660
Publish_to：
American Journal of Cancer Research
PMID：
34249443
Mechanism Analysis of a Novel Angiotensin-I-Converting Enzyme Inhibitory Peptide from Isochrysis zhanjiangensis Microalgae for Suppressing Vascular Injury in Human Umbilical Vein Endothelial Cells
点击查看 >>
Author：
Chen J; Tan L; Li C; Zhou C; Hong P; Sun S; Qian Z
IF：
6.1000
Publish_to：
J Agric Food Chem
PMID：
32212693
Graphene oxide induces autophagy and apoptosis via the ROS-dependent AMPK/mTOR/ULK-1 pathway in colorectal cancer cells
点击查看 >>
Author：
Jiamen Shen, Jiatian Dong, Feng Shao, Jiaying Zhao, Lifeng Gong, Huipeng Wang, Wenjie Chen, Yafei Zhang, Yuankun Cai
IF：
6.0960
Publish_to：
Nanomedicine
PMID：
35394351
Algicidal Effects of a High-Efficiency Algicidal Bacterium Shewanella Y1 on the Toxic Bloom-Causing Dinoflagellate Alexandrium pacificum
点击查看 >>
Author：
Xi Chen, Dengyu Wang, Yanqun Wang, Pengfei Sun, Shuanghui Ma, Tiantian Chen
IF：
6.0850
Publish_to：
Marine Drugs
PMID：
35447912
Apoptosis-mediated anti-proliferative activity of Calligonum comosum against human breast cancer cells, and molecular docking of its major polyphenolics to Caspase-3
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Author：
Ashok Kumar, Mohammad A Alfhili, Ahmed Bari, Hanane Ennaji, Maqusood Ahamed, Mohammed Bourhia, Mohamed Chebaibi, Laila Benbacer, Hazem K Ghneim, Manal Abudawood, Khalid M Alghamdi, John P Giesy, Yazeed A Al-Sheikh, Mourad A M Aboul-Soud
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
36299484
Single Gold Nanostars Achieve Inherent Cascade Catalytic and Near-Infrared Photothermal Activities for Efficient Tumor Therapy
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Author：
Meijun Zhao, Yuxuan Li, Yian Liu, Lintao Bai, Junjie Ma, Mei Ren, Jiahui Liu, Heyun Shen
IF：
6.0690
Publish_to：
BIOCONJUGATE CHEMISTRY
PMID：
36111663
Carbon dots nanozyme for anti-inflammatory therapy via scavenging intracellular reactive oxygen species
点击查看 >>
Author：
Chen Dong, Xuehua Ma, Yi Huang, Yujie Zhang, Xiang Gao
IF：
6.0640
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
36046669
Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis
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Author：
Xingyao Pei, Haiyang Jiang, Xinyu Liu, Liuan Li, Cun Li, Xilong Xiao, Daowen Li, Shusheng Tang
IF：
6.0250
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
33762183
Probiotic Characteristics and Anti-Inflammatory Effects of Limosilactobacillus fermentum 664 Isolated from Chinese Fermented Pickles
点击查看 >>
Author：
Huichao Hao, Ziyu Nie, Yanyang Wu, Zhiwei Liu, Fenglian Luo, Fangming Deng, Lingyan Zhao
IF：
6.0000
Publish_to：
Antioxidants
PMID：
38929142
PBA functionalized single-atom Fe for efficient therapy of multidrug-resistant bacterial infections
点击查看 >>
Author：
Ruigeng Yang, Yueru Wei, Mengyang Zhao, Mengxiao Shi, Yongxing Zhao, Pengchao Sun
IF：
5.9990
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
PMID：
36067683
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway
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Author：
Fang Jie, She Jing, Lin Fang, Wu Jun-Chao, Han Rong, Sheng Rui, Wang Guanghui, Qin Zheng-Hong
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35462935
Anti-Oxidation and Anti-Inflammatory Potency Evaluation of Ferulic Acid Derivatives Obtained through Virtual Screening
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Author：
Yuqi Shi, Xuelian Chen, Shaojia Qiang, Jie Su, Jiazhong Li
IF：
5.9240
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
34768735
Investigating the Antidepressant Mechanisms of Polygonum sibiricum Polysaccharides via Microglial Polarization
点击查看 >>
Author：
Yingyu Zhang, Danyang Wang, Jiameng Liu, Jing Sun, Xinmin Liu, Bei Fan, Cong Lu, Fengzhong Wang
IF：
5.9000
Publish_to：
Nutrients
PMID：
38337722
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model
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Author：
Tengteng Huang, Qiangjun Che, Xiaoling Chen, Daiwen Chen, Bing Yu, Jun He, Hong Chen, Hui Yan, Ping Zheng, Yuheng Luo, Zhiqing Huang
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
35679090
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species
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Author：
Wenzheng Pan, Lin Zheng, Jiawei Gao, Lin Ye, Zhenzhong Chen, Shijie Liu, Bin Pan, Jiawei Fang, Hehuan Lai, Yejin Zhang, Kainai Ni, Chao Lou, Dengwei He
IF：
5.8580
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
34801525
The Anti-Neuroinflammatory Effect of Fuzi and Ganjiang Extraction on LPS-Induced BV2 Microglia and Its Intervention Function on Depression-Like Behavior of Cancer-Related Fatigue Model Mice
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Author：
Yang Songwei, Yang Yantao, Chen Cong, Wang Huiqin, Ai Qidi, Lin Meiyu, Zeng Qi, Zhang Yi, Gao Yan, Li Xun, Chen Naihong
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34122094
High aspect ratio plasmonic Au/Ag nanorods-mediated NIR-II photothermally enhanced nanozyme catalytic cancer therapy
点击查看 >>
Author：
Xinyu Cui, Minghui Li, Lei Tong, Miaojing Li, Xuefeng Tang, Xiaojun Han
IF：
5.8000
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
PMID：
36724564
Functional Characterization of Serotonin N-Acetyltransferase Genes (SNAT1/2) in Melatonin Biosynthesis of Hypericum perforatum.
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Author：
Wen Zhou, Shu Yang, Qian Zhang, Ruyi Xiao, Bin Li, Donghao Wang, Junfeng Niu, Shiqiang Wang, Zhezhi Wang
IF：
5.7540
Publish_to：
Frontiers in Plant Science
PMID：
34950170
Mechanism of two alkaloids isolated from coral endophytic fungus for suppressing angiogenesis in atherosclerotic plaque in HUVEC
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Author：
Yi Liu, Yanmei Li, Minqi Chen, Yayue Liu, Jinyue Liang, Yi Zhang, Zhong-Ji Qian
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
35704971
Intracellular behavior of Nocardia seriolae and its apoptotic effect on RAW264.7 macrophages
点击查看 >>
Author：
Liu Wenwen, Deng Yuting, Tan Aiping, Zhao Fei, Chang Ouqing, Wang Fang, Lai Yingtiao, Huang Zhibin
IF：
5.7000
Publish_to：
Frontiers in Cellular and Infection Microbiology
PMID：
36926518
TRDMT1 participates in the DNA damage repair of granulosa cells in premature ovarian failure
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Author：
Chunli Sha, Lu Chen, Li Lin, Taoqiong Li, Hong Wei, Meiling Yang, Wujiang Gao, Dan Zhao, Qi Chen, Yueqin Liu, Xiaofang Chen, Wenlin Xu, Yuefeng Li, Xiaolan Zhu
IF：
5.6820
Publish_to：
Aging-US
PMID：
34100772
Pirfenidone ameliorates early pulmonary fibrosis in LPS-induced acute respiratory distress syndrome by inhibiting endothelial-to-mesenchymal transition via the Hedgehog signaling pathway
点击查看 >>
Author：
Zhang R; Tan Y; Yong C; Jiao Y; Tang X; Wang D
IF：
5.6000
Publish_to：
Int Immunopharmacol
PMID：
35504205
A New Mechanism for Ginsenoside Rb1 to Promote Glucose Uptake, Regulating Riboflavin Metabolism and Redox Homeostasis
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Author：
Yihan Liu, Yuchan Deng, Fengyu Wang, Xiaoyi Liu, Jiaqi Wang, Jian Xiao, Cunli Zhang, Qiang Zhang
IF：
5.5810
Publish_to：
Metabolites
PMID：
36355094
Surface-Decorated Graphene Oxide Sheets with Copper Nanoderivatives for Bone Regeneration: An In Vitro and In Vivo Study Regarding Molecular Mechanisms, Osteogenesis, and Anti-infection Potential
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Author：
Ying Yang, Min Li, Hang Luo, Dou Zhang
IF：
5.5780
Publish_to：
ACS Infectious Diseases
PMID：
35188739
Upregulation of Wnt2b exerts neuroprotective effect by alleviating mitochondrial dysfunction in Alzheimer's disease
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Author：
Ling-Zhi Xu, Bing-Qiu Li, Fang-Yu Li, Mei-Na Quan, Wei Qin, Ying Li, Wen-Wen Li, Yu Zhao, Yi-Ping Wei, Jian-Ping Jia
IF：
5.5000
Publish_to：
CNS Neuroscience & Therapeutics
PMID：
36852442
Volatile Organic Compounds Produced by a Deep-Sea Bacterium Efficiently Inhibit the Growth of Pseudomonas aeruginosa PAO1
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Author：
Yuanyuan Hu, Ge Liu, Chaomin Sun, Shimei Wu
IF：
5.4000
Publish_to：
Marine Drugs
PMID：
38786624
The petroleum ether extract of Brassica rapa L. induces apoptosis of lung adenocarcinoma cells via the mitochondria-dependent pathway
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Author：
Xierenguli Halike, Jinyu Li, Pengfei Yuan, Kaimeiliya Yasheng, Min Chen, Lijie Xia, Jinyao Li
IF：
5.3960
Publish_to：
Food & Function
PMID：
34523644
Biocompatible 2D Cu-TCPP Nanosheets Derived from Cu2O Nanocubes as Multifunctional Nanoplatforms for Combined Anticancer Therapy
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Author：
Le Gao, Yibo Song, Jun Zhong, Xiaofeng Lin, Shu-Feng Zhou, Guowu Zhan
IF：
5.3950
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
35129963
Mild Hyperthermia Induced by Hollow Mesoporous Prussian Blue Nanoparticles in Alliance with a Low Concentration of Hydrogen Peroxide Shows Powerful Antibacterial Effect
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Author：
Yuting Li, Yun Zhu, Cheng Wang, Yue Shen, Li Liu, Shuwen Zhou, Peng-Fei Cui, Huaanzi Hu, Pengju Jiang, Xinye Ni, Lin Qiu, Jianhao Wang
IF：
5.3640
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
35170976
Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF-β/Smad signalling in type 2 diabetic rats
点击查看 >>
Author：
Jingjing Tian, Mingjun Zhang, Mengying Suo, Dian Liu, Xuyang Wang, Ming Liu, Jinyu Pan, Tao Jin, Fengshuang An
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
34169635
Improving the anti-tumor effect of EGCG in colorectal cancer cells by blocking EGCG-induced YAP activation
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Author：
Yu Wang, Sha-Sha Jin, Dan-Ting Li, Xiao-Chun Jiang, Afrasiyab, Anam Khalid, Xin Liu, Hui-Lin Wang, Hai-Yan Wang, Zai-Gui Wang, Zhong-Wen Xie, Shou-Jun Huang
IF：
5.3000
Publish_to：
American Journal of Cancer Research
PMID：
37168333
Novel chloroquine derivative suppresses melanoma cell growth by DNA damage through increasing ROS levels
点击查看 >>
Author：
Jiaoduan Li, Jing Long, Jianglin Zhang, Nian Liu, Bei Yan, Ling Tang, Xiang Chen, Cong Peng
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
35332658
Metallothionein Attenuated Arsenic-Induced Cytotoxicity: The Underlying Mechanism Reflected by Metabolomics and Lipidomics
点击查看 >>
Author：
Zihe Qi, Qinghong Wang, Haitao Wang, Mingqian Tan
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
33939412
Iron overload in endometriosis peritoneal fluid induces early embryo ferroptosis mediated by HMOX1
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Author：
Li Shishi, Zhou Yier, Huang Qiongxiao, Fu Xiaohua, Zhang Ling, Gao Fang, Jin Zhen, Wu Limei, Shu Chongyi, Zhang Xirong, Xu Weihai, Shu Jing
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
34782602
Antibacterial Properties and Mechanism of Lysozyme-Modified ZnO Nanoparticles
点击查看 >>
Author：
Kangrui Yuan, Xiaoliu Liu, Jianxin Shi, Wei Liu, Kun Liu, Hongmei Lu, Dudu Wu, Zhi Chen, Chengyu Lu
IF：
5.2210
Publish_to：
Frontiers in Chemistry
PMID：
34900934
Thiacloprid-induced hepatotoxicity in zebrafish: Activation of the extrinsic and intrinsic apoptosis pathways regulated by p53 signaling pathway
点击查看 >>
Author：
Zhongtang Xie, Guanghua Lu, Ranran Zhou, Yuchen Ma
IF：
5.2020
Publish_to：
AQUATIC TOXICOLOGY
PMID：
35349858
Antifungal mechanism of cell-free supernatant produced by Trichoderma virens and its efficacy for the control of pear Valsa canker
点击查看 >>
Author：
Zhang Yang, Lu Ying, Jin Zhaoyang, Li Bo, Wu Li, He Yujian
IF：
5.2000
Publish_to：
Frontiers in Microbiology
PMID：
38694806
Dendrobium nobile Lindl. Polysaccharides protect fibroblasts against UVA-induced photoaging via JNK/c-Jun/MMPs pathway
点击查看 >>
Author：
Wei Li, Xingrui Mu, Xingqian Wu, Wenjie He, Ye Liu, Yiqiu Liu, Junyu Deng, Xuqiang Nie
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
35973631
NRF2-suppressed vascular calcification by regulating the antioxidant pathway in chronic kidney disease
点击查看 >>
Author：
Donghua Jin, Lihua Lin, Yuxian Xie, Miao Jia, Hong Qiu, Kang Xun
IF：
5.1920
Publish_to：
FASEB JOURNAL
PMID：
34918390
ACE Inhibitory Peptide from Skin Collagen Hydrolysate of Takifugu bimaculatus as Potential for Protecting HUVECs Injury
点击查看 >>
Author：
Shuilin Cai, Nan Pan, Min Xu, Yongchang Su, Kun Qiao, Bei Chen, Bingde Zheng, Meitian Xiao, Zhiyu Liu
IF：
5.1180
Publish_to：
Marine Drugs
PMID：
34940654
Phytosphingosine inhibits the growth of lung adenocarcinoma cells by inducing G2/M-phase arrest. apoptosis. and mitochondria-dependent pathway cell death in vitro and in vivo
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Author：
Qi Cai， Min Chen， Bo Wang， Jin Wang， Lijie Xia， Jinyao Li
IF：
5.1000
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
37956922
Melatonin alleviates acute respiratory distress syndrome by inhibiting alveolar macrophage NLRP3 inflammasomes through the ROS/HIF-1α/GLUT1 pathway
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Author：
Li Zheng, Wenyu Zhou, Yutong Wu, Wenting Xu, Song Hu, Yiguo Zhang, Huan Xu, Huimin Deng, Yuanli Chen, Lingmin Wu, Juan Wei, Di Feng, Mansi Wang, Huanping Zhou, Quanfu Li, Lina Zhu, Hao Yang, Xin Lv
IF：
5.0000
Publish_to：
LABORATORY INVESTIGATION
PMID：
37871834
Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway
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Author：
Fei Zhu, Juan Shao, Yunlin Tian, Zhiguo Xu
IF：
4.9320
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
34653733
Pro-Apoptotic Effect of Zeolitic Imidazolate Framework-8 (ZIF-8)-Loaded Dihydromyricetin on HepG2 Cells
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Author：
Xiao Mi, Juan Lu, Mingran Dong, Yang Lou, Xia Zhan, Xi Chen
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36080252
A Combination of Biocatalysis and Fenton-Like Reaction Induced OH• Burst for Cascade Amplification of Cancer Chemodynamic Therapy
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Author：
Xiaopeng Xu, Minghui Li, Wenjia Xu, Min Wang, Yan Wu, Liying Cheng, Jinyang Li, Yang Qin, Sha Liu, Gangqiang Yang, Kaoxiang Sun, Peng Zhang
IF：
4.9000
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
38781419
Finerenone attenuates myocardial apoptosis; metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus
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Author：
Jin Tao; Fu Xiangrui; Liu Ming; An Fengshuang
IF：
4.8000
Publish_to：
Diabetology & Metabolic Syndrome
PMID：
37120554
Xiao Z, Yang S, Liu Y, Zhou C, Hong P, Sun S, Qian ZJ.
点击查看 >>
Author：
A novel glyceroglycolipid from brown algae Ishige
IF：
4.7910
Publish_to：
Chem Biol Interact.
PMID：
34740599
Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance
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Author：
Chuanfen Zhang, Chunmei Wang, Zhenyu Yang, Yuquan Bai, Takehito Shukuya, Mau-Ern Poh, Simon Ekman, Jian Li, Yuyang Xu, Senyi Deng
IF：
4.7260
Publish_to：
Translational Lung Cancer Research
PMID：
35693278
Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis
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Author：
Sisi Shao, Yaoxin Liu, Wanzi Hong, Yuanxi Mo, Fen Shu, Lei Jiang, Ning Tan
IF：
4.7000
Publish_to：
Biomedicines
PMID：
36831172
Baicalein protects PC12 cells from Aβ25-35-induced cytotoxicity via inhibition of apoptosis and metabolic disorders
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Author：
Gao L; Zhou F; Wang KX; Zhou YZ; Du GH; Qin XM
IF：
4.6590
Publish_to：
Life Sci
PMID：
32112868
Carbon 60 Dissolved in Grapeseed Oil Inhibits Dextran Sodium Sulfate-Induced Experimental Colitis
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Author：
Rayko Lazcano-Silveira, Xiaoxiao Jia, Kaixuan Liu, Honggang Liu, Xinrong Li, Mizhou Hui
IF：
4.6310
Publish_to：
Journal of Inflammation Research
PMID：
35915853
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling
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Author：
Siwen Li, Yanling Wang, Dongke Yu, Yuan Zhang, Xiali Wang, Mei Shi, Yanxin Xiao, Xinlian Li, Hongtao Xiao, Lu Chen, Xuan Xiong
IF：
4.6220
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
36057428
Ultrasmall Fe3O4 nanoparticles self-assembly induced dual-mode T1/T2-weighted magnetic resonance imaging and enhanced tumor synergetic theranostics.
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Author：
Qinghua Xie, Xuemei Wang, Gaorui Zhang, Dawei Zhou, Yuxuan Zhao, Hong Liu, Jiazhi Duan, Dexin Yu, Yuanhua Sang
IF：
4.6000
Publish_to：
Scientific Reports
PMID：
38724530
Neuroglobin protects against cerebral ischemia/reperfusion injury in rats by suppressing mitochondrial dysfunction and endoplasmic reticulum stress-mediated neuronal apoptosis through synaptotagmin-1
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Author：
Lihong Zhang, Di Li, Lin Yin, Ce Zhang, Hong Qu, Jianping Xu
IF：
4.5000
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
37195900
The Role of Ferroptosis in the Damage of Human Proximal Tubule Epithelial Cells Caused by Perfluorooctane Sulfonate
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Author：
Pingwei Wang, Dongge Liu, Shuqi Yan, Yujun Liang, Jiajing Cui, Li Guo, Shuping Ren, Peng Chen
IF：
4.4720
Publish_to：
Toxics
PMID：
36006114
Transcriptome analysis of emamectin benzoate caused midgut damage by inducing oxidative stress, energy metabolism disorder and apoptosis in gypsy moth (Lymantria dispar)
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Author：
Zhe Xu, Lu Li, Jianyang Bai, Yue Zhang, Mengru Min, Wei Ma, Ling Ma
IF：
4.4620
Publish_to：
PEST MANAGEMENT SCIENCE
PMID：
35861673
Geraniin inhibits whole blood IFN-γ and IL-6 and promotes IL-1β and IL-8, and stimulates calcium-dependent and sucrose-sensitive erythrocyte death
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Author：
Jawaher Alsughayyir, Wafa Alshaiddi, Roua Alsubki, Amal Alshammary, Ahmed M. Basudan, Mohammad A. Alfhili
IF：
4.4600
Publish_to：
TOXICOLOGY AND APPLIED PHARMACOLOGY
PMID：
35026210
Hypoxia and pH co-triggered oxidative stress amplifier for tumor therapy
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Author：
Fenglan Qin, Huige Zhou, Jiayang Li, Jing Liu, Yaling Wang, Ru Bai, Shihui Liu, Manman Ma, Tao Liu, Fene Gao, Peiyao Du, Xiaoquan Lu, Chunying Chen
IF：
4.4320
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
34048738
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2
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Author：
Yang Jinghui, Guo Qian, Wang Lu, Yu Shan
IF：
4.4140
Publish_to：
NEUROCHEMICAL RESEARCH
PMID：
36306010
Protective Effects and Mechanisms of Procyanidins on Parkinson’s Disease In Vivo and In Vitro
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Author：
Juan Chen, Yixuan Chen, Yangfan Zheng, Jiawen Zhao, Huilin Yu, Jiajin Zhu, Duo Li
IF：
4.4120
Publish_to：
MOLECULES
PMID：
34577027
Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling
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Author：
Lin Xiaohuang, Zhang Jian, Wu Zekai, Shi Yuan, Chen Mengting, Li Maodong, Hu Hong, Tian Kun, Lv Xiaoqi, Li Chutao, Liu Yang, Gao Xinyue, Yang Qiaomei, Chen Kunqi, Zhu An
IF：
4.4000
Publish_to：
Frontiers in Pharmacology
PMID：
38939838
The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy
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Author：
Chen M. Gowd V. Wang M. Chen F. Cheng KW
IF：
4.3720
Publish_to：
Food Funct
PMID：
33291138
Paeonol protects melanocytes against hydrogen peroxide-induced oxidative stress through activation of Nrf2 signaling pathway
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Author：
Shanshan Guo, Qiang Zhang
IF：
4.3600
Publish_to：
DRUG DEVELOPMENT RESEARCH
PMID：
33491230
Diabetic ferroptosis plays an important role in triggering on inflammation in diabetic wound
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Author：
Shuangwen Li, Yuan Li, Ziyu Wu, Zhongming Wu, Hongjuan Fang
IF：
4.3100
Publish_to：
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
PMID：
34423682
Mesenchymal stem cell-derived extracellular vesicles relieve endothelial cell senescence via recovering CTRP9 upon repressing miR-674-5p in atherosclerosis
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Author：
Min Zeng, Yangli He, Yali Yang, Mengdi Wang, Yue Chen, Xin Wei
IF：
4.3000
Publish_to：
Regenerative Therapy
PMID：
38645280
Effects of lanthanum nitrate on behavioral disorder, neuronal damage and gene expression in different developmental stages of Caenorhabditis elegans
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Author：
Gao-chao Han, Hai-ming Jing, Wen-jing Zhang, Nan Zhang, Zi-nan Li, Guo-yan Zhang, Shan Gao, Jun-yu Ning, Guo-jun Li
IF：
4.2210
Publish_to：
TOXICOLOGY
PMID：
34718030
[FeIIICl(TMPPH2)][FeIIICl4]2: A Stand-Alone Molecular Nanomedicine That Induces High Cytotoxicity by Ferroptosis
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Author：
Xiao Wang, Jia-Hao Feng, Chun-Mei Zeng, Ze-Sheng Zhang, Feng-Lin Cao, Wen-Hua Zhang, Jin-Xiang Chen, David J. Young
IF：
4.2000
Publish_to：
MOLECULES
PMID：
38893373
Altered expression of ferroptosis markers and iron metabolism reveals a potential role of ferroptosis in vitiligo
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Author：
Xiuyi Wu, Shanglin Jin, Yiwen Yang, Xiaoli Lu, Xiaoxi Dai, Zhongyi Xu, Chengfeng Zhang, Leihong Flora Xiang
IF：
4.1590
Publish_to：
Pigment Cell & Melanoma Research
PMID：
35218147
Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway
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Author：
Wang Z. Wang L. Wang J. Luo J. Ruan H. Zhang J
IF：
4.1300
Publish_to：
Sci Rep
PMID：
32973191
Inhibition of USP15 ameliorates high-glucose-induced oxidative stress and inflammatory injury in podocytes through regulation of the Keap1/Nrf2 signaling
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Author：
Erdi Xu, Chunyan Yin, Xiaoqing Yi, Yuesheng Liu
IF：
4.1190
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
34931430
The alleviative effect of C-phycocyanin peptides against TNBS-induced inflammatory bowel disease in zebrafish via the MAPK/Nrf2 signaling pathways
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Author：
Fenghua Xu, Fei Yang, Yuezi Qiu, Chuansen Wang, Qinglin Zou, Lizhen Wang, Xiaobin Li, Meng Jin, Kechun Liu, Shanshan Zhang, Yun Zhang, Bing Li
IF：
4.1000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
38171429
Vitamin D suppresses ferroptosis and protects against neonatal hypoxic-ischemic encephalopathy by activating the Nrf2/HO-1 pathway
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Author：
Yueju Cai, Xiaolan Li, Xuying Tan, Ping Wang, Xiaopeng Zhao, Huayan Zhang, Yanyan Song
IF：
4.0470
Publish_to：
Translational Pediatrics
PMID：
36345441
Multi-activity cobalt ferrite/MXene nanoenzymes for drug-free phototherapy in bacterial infection treatment
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Author：
Jiacheng Shi, Rui Shu, Xiuyuan Shi, Yunfei Li, Jiangge Li, Yi Deng, Weizhong Yang
IF：
4.0360
Publish_to：
RSC Advances
PMID：
35425054
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro
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Author：
Xiao-Xin Gao, Chen-Hao Liu, Zhi-Lei Hu, Hai-Yin Li, Xian Chang, Yue-Yang Li, Yu-Yao Zhang, Yu Zhai, Chang-Qing Li
IF：
4.0090
Publish_to：
Frontiers in Bioscience-Landmark
PMID：
34719207
Melatonin protects Leydig cells from HT-2 toxin-induced ferroptosis and apoptosis via glucose-6-phosphate dehydrogenase/glutathione -dependent pathway
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Author：
Jianyu Ma, Yuquan Han, Hua Yang, Liang Liu, Zongyou Wei, Feng Wang, Yongjie Wan
IF：
4.0000
Publish_to：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
PMID：
37023974
Extracellular Mitochondria Activate Microglia and Contribute to Neuroinflammation in Traumatic Brain Injury
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Author：
Zhang Chaonan, Liu Chuan, Li Fanjian, Zheng Mutian, Liu Yafan, Li Lei, Yang Huaijin, Zhang Shu, Wang Chongjin, Rong Hongtao, Guo Hui, Li Ying, Li Ying, Fu Ying, Zhao Zilong, Zhang Jianning
IF：
3.9780
Publish_to：
NEUROTOXICITY RESEARCH
PMID：
36087194
Antifungal effect of volatile organic compounds produced by Pseudomonas chlororaphis subsp. aureofaciens SPS-41 on oxidative stress and mitochondrial dysfunction of Ceratocystis fimbriata
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Author：
Yu Zhang, Tengjie Li, Mingjie Xu, Jianheng Guo, Chunmei Zhang, Zhaozhong Feng, Xue Peng, Zongyun Li, Ke Xing, Sheng Qin
IF：
3.9630
Publish_to：
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
PMID：
33771256
Carboxymethylcellulose encapsulated fingolimod, siRNA@ZnO hybrid nanocomposite as a new anti-Alzheimer's material
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Author：
Nuha B. Aljohani, Safaa Y. Qusti, Madeeha Alsiny, Fadwa Aljoud, Norah Bakheet Aljohani, Eman S. Alsolami, Khalid A. Alamry, Mahmoud A. Hussein
IF：
3.9000
Publish_to：
RSC Advances
PMID：
39006767
Gold nanoparticle-based nanoprobes with enhanced tumor targeting and photothermal/photodynamic response for therapy of osteosarcoma
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Author：
Shengren Xiong, Guosheng Xiong, Zhaohui Li, Qing Jiang, Jia Yin, Ting Yin, Hong Zheng
IF：
3.8740
Publish_to：
NANOTECHNOLOGY
PMID：
33395672
Microbial metabolite sodium butyrate enhances the anti-tumor efficacy of 5-fluorouracil against colorectal cancer by modulating PINK1/Parkin signaling and intestinal flora
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Author：
Li Yangbo, He Pengzhan, Chen Ying, Hu Jiaming, Deng Beiying, Liu Chuan, Yu Baoping, Dong Weiguo
IF：
3.8000
Publish_to：
Scientific Reports
PMID：
38844824
Resolvin D1 attenuates sepsis induced acute kidney injury targeting mitochondria and NF-κB signaling pathway
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Author：
Liya Wang, Jiameng Li, Ruoxi Liao, Yupei Li, Luojia Jiang, Zhuyun Zhang, Jiwen Geng, Ping Fu, Baihai Su, Yuliang Zhao
IF：
3.7760
Publish_to：
Heliyon
PMID：
36578378
MXene Quantum Dot/Zeolitic Imidazolate Framework Nanocarriers for Dual Stimulus Triggered Tumor Chemo-Phototherapy
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Author：
Xin Feng, Mingjun Li, Jianming Wang, Xianrui Zou, Hongshui Wang, Donghui Wang, Huan Zhou, Lei Yang, Wei Gao, Chunyong Liang
IF：
3.7480
Publish_to：
Materials
PMID：
35806667
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition
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Author：
Ziyu Wu， Dan Li， Dingyuan Tian， Xuejun Liu， Zhongming Wu
IF：
3.7000
Publish_to：
PLoS One
PMID：
36516169
Bioactive polyphenols separated from hemp seed shells ameliorate H2O2-induced oxidative stress injury in human umbilical vein endothelial cells
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Author：
Peng-Wei Xu, Xiao-Fan Yuan, Bing Zhao
IF：
3.6930
Publish_to：
JOURNAL OF FOOD SCIENCE
PMID：
36524844
Effect of fumonisin B1 on oxidative stress and gene expression alteration of nutrient transporters in porcine intestinal cells
点击查看 >>
Author：
Zhigang Chen, Lihua Zhou, Qiaoling Yuan, Huiyu Chen, Hongyu Lei, Jianming Su
IF：
3.6520
Publish_to：
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
PMID：
33443779
Platelet-rich plasma promotes diabetic ulcer repair through inhibition of ferroptosis
点击查看 >>
Author：
Li Chen, Daoai Wu, Lili Zhou, Yan Ye
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
36388823
The protective effects of Clerodendranthus spicatus (Thunb.) C. Y. Wu extract on oxidative stress induced by 2;2'-azo (2-methylpropamidine) dihydrochloride in HL-1 mouse cardiomyocytes
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Author：
Li Y; Wang J; Jiang J; Li X; Wang M
IF：
3.6000
Publish_to：
Front Cardiovasc Med
PMID：
36158816
FAM96A knock-out promotes alternative macrophage polarization and protects mice against sepsis
点击查看 >>
Author：
Yin A, Chen W, Cao L, Li Q, Zhu X, Wang L
IF：
3.5320
Publish_to：
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
PMID：
33232517
Influence of the Hypercapnic Tumor Microenvironment on the Viability of Hela Cells Screened by a CO2-Gradient-Generating Device
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Author：
Shu Zhang, Yamin Yang, Sijia Liu, Rui Dong, Zhiyu Qian
IF：
3.5120
Publish_to：
ACS Omega
PMID：
34661031
The Role of Tea Tree Oil in Alleviating Palmitic Acid-Induced Lipid Accumulation in Bovine Hepatocytes
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Author：
Yang Tianyu, Ma Xiaoyu, Jiang Maocheng, Cheng Zhiqiang, Datsomor Osmond, Zhao Guoqi, Zhan Kang
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
35127885
Discovery of Antitumor Active Peptides Derived from Peroxiredoxin 5
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Author：
Juanjuan Liu, Sen Zou, Yan Zhang, Ru Lin, Yanbo Duan, Weiqing He, Zhaoyong Yang
IF：
3.4660
Publish_to：
ChemMedChem
PMID：
34313010
Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor
点击查看 >>
Author：
Zhu Qin, Zhou Yanqing, Wang Haixia, Cao Tao, Wang Xinzhi, Liu Rui, Wu Hao, Lin Binyan
IF：
3.4000
Publish_to：
MEDICAL ONCOLOGY
PMID：
37421513
Extracellular vesicles derived from Pinctada martensii mucus regulate skin inflammation via the NF-κB/NLRP3/MAPK pathway
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Author：
Zijie Wu, Lihua Ma, Peichun Lin, Zhenqing Dai, Zifan Lu, Linhong Yan, Chunxia Zhou, Zhong-Ji Qian, Pengzhi Hong, Chengyong Li
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
36228540
Isoliquiritin modulates ferroptosis via NF-κB signaling inhibition and alleviates doxorubicin resistance in breast cancer
点击查看 >>
Author：
Jiguo Wang, Yang Li, Jing Zhang, Changguo Luo
IF：
3.3000
Publish_to：
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
PMID：
36605015
Antifungal activity of volatile compounds generated by endophytic fungi Sarocladium brachiariae HND5 against Fusarium oxysporum f. sp. cubense
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Author：
Yang Yang, Yipeng Chen, Jimiao Cai, Xianbao Liu, Guixiu Huang
IF：
3.2400
Publish_to：
PLoS One
PMID：
34855862
Luminescence performance and antioxidant properties of selenium carbon dots prepared from selenium-hyperaccumulating plants
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Author：
Jingwen Cui, Yuwei Yang, Yashuai Zhang, Xu Yang, Yu Liu, Jianfeng Tan, Shaowei Wu, Zhuo Liu
IF：
3.2000
Publish_to：
LUMINESCENCE
PMID：
39152781
Study on the mechanism of photodynamic therapy mediated by 5-aminoketovalerate in human ovarian cancer cell line
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Author：
Wang Qian, Suo Yuping, Wang Xiaoni, Wang Yulan, Tian Xiaojuan, Gao Yanxia, Liu Nannan, Liu Rui
IF：
3.1610
Publish_to：
LASERS IN MEDICAL SCIENCE
PMID：
33392781
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress
点击查看 >>
Author：
Junyu Fan, Manqi Liu, Xiaomin Li, ShengLan Gao, Yahong Wang, Ao Li, Lujun Chen, Dengshuang Zhou, Hongqiao Chen, Zhiliang Xu, Zijun Wu, Keng Wu
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
36791545
3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis
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Author：
Tianyu Liu, Lei Yang, Hejun Gao, Yuzhen Zhuo, Zhengwei Tu, Yongqin Wang, Jing Xun, Qi Zhang, Lanqiu Zhang, Ximo Wang
IF：
3.0610
Publish_to：
PeerJ
PMID：
35310165
Epidemic dropsy toxin, sanguinarine chloride, stimulates sucrose-sensitive hemolysis and breakdown of membrane phospholipid asymmetry in human erythrocytes.
点击查看 >>
Author：
Alfhili MA, Alsughayyir J, Basudan AB.
IF：
3.0330
Publish_to：
Toxicon.
PMID：
34081931
Mitochondrial changes in fish cells in vitro in response to serum deprivation
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Author：
Fan Xiaoteng, Yan Tao, Hou Tingting, Xiong Xiaofan, Feng Leilei, Li Shiyi, Wang Zaizhao
IF：
3.0140
Publish_to：
FISH PHYSIOLOGY AND BIOCHEMISTRY
PMID：
35652993
Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury
点击查看 >>
Author：
Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang
IF：
3.0000
Publish_to：
RENAL FAILURE
PMID：
38584135
Daphnoretin induces reactive oxygen species‑mediated apoptosis in melanoma cells
点击查看 >>
Author：
Hui Wang, Xue Hu, Minjing Li, Zhaohai Pan, Defang Li, Qiusheng Zheng
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
33907563
Dihydroartemisinin induces ferroptosis in T cell acute lymphoblastic leukemia cells by downregulating SLC7A11 and activating the ATF4‑CHOP signaling pathway
点击查看 >>
Author：
Na Tang, Xinling Liu, Yong Liu, Haihua Wang, Yao Zhao, Haiying Wang, Zhenbo Hu
IF：
2.9000
Publish_to：
Oncology Letters
PMID：
38846431
An integrated proteomic and phosphoproteomic landscape of chronic kidney disease
点击查看 >>
Author：
Linxiao Sun, Cheng Wang, Zhongjing Zhou, Qiangqiang Li
IF：
2.8000
Publish_to：
Journal of Proteomics
PMID：
39547397
Neuroprotective effect of Ginsenoside Re against neurotoxin induced Parkinson's disease models via induction of Nrf2.
点击查看 >>
Author：
Qiao J, Zhao Y, Liu Y, Zhang S, Zhao W, Liu S, Liu
IF：
2.7730
Publish_to：
Mol Med Rep.
PMID：
35543148
Investigation and assessment of neutrophil dysfunction early after severe burn injury
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Author：
Yunxi Yang, Lu Liu, Zaiwen Guo, Linbin Li, Yiming Shao, Mingming Song, Bingwei Sun
IF：
2.7440
Publish_to：
BURNS
PMID：
33820675
The active ingredient (DSH-20) of Salvia miltiorrhiza flower reduces oxidative damage and apoptosis in cardiomyocytes by regulating miR-1
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Author：
Cao Panxia, Xue Yanpin, Guo Mengjiao, Jiang Xue, Lei Zhen, Gao Shuibo, Wang Xinzhou, Gao Haixia, Han Yongjun, Chang Hongbo, Liu Shanshan, Dai Liping, Wu Hong
IF：
2.7420
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
35179668
Reprogramming of erythrocyte lifespan by NFκB-TNFα naphthoquinone antagonist β-lapachone is regulated by calcium overload and CK1α
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Author：
Mohammad A. Alfhili, Jawaher Alsughayyir, Ahmed M. Basudan
IF：
2.7200
Publish_to：
JOURNAL OF FOOD BIOCHEMISTRY
PMID：
33749832
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc−-GSH-GPX4 signaling pathway in ferroptosis response
点击查看 >>
Author：
Xuan Ni, Chen Gao, Xiaolin Zhu, Xiaosong Zhang, Yizhuo Fang, Zhihui Hao
IF：
2.7000
Publish_to：
JOURNAL OF APPLIED TOXICOLOGY
PMID：
38581191
Effect of Selenium and Peroxynitrite on Immune Function of Immature Dendritic Cells in Humans
点击查看 >>
Author：
Huan Xia, Liangliang Zhang, Jie Dai, Xianmei Liu, Xin Zhang, Zhu Zeng, Yi Jia
IF：
2.6490
Publish_to：
MEDICAL SCIENCE MONITOR
PMID：
33684094
Hepatoprotective effect of diammonium glycyrrhizinate and neuroprotective effect of piperazine ferulate on AmB-induced liver and kidney injury by suppressing apoptosis in vitro and in vivo
点击查看 >>
Author：
Xu He, Xiuhong Peng, Suyu Zhang, Tianfeng Yang, Jian Huo, Yanmin Zhang
IF：
2.6000
Publish_to：
TOXICON
PMID：
38849008
Bone marrow mesenchymal stem cells-derived exosomes mediated delivery of tetramethylpyrazine attenuate cerebral ischemic injury
点击查看 >>
Author：
Guozhen Zhang, Bin Xu, Jinlong Mao, Ruicun Liu
IF：
2.5000
Publish_to：
Journal of Stroke & Cerebrovascular Diseases
PMID：
37738917
Hispidin inhibits LPS‑induced nitric oxide production in BV‑2 microglial cells via ROS‑dependent MAPK signaling
点击查看 >>
Author：
Mei-Hua Jin, Dong-Qin Chen, Ying-Hua Jin, Ying-Hao Han, Hu-Nan Sun, Taeho Kwon
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
34335912
TMEM16F mediated phosphatidylserine exposure and microparticle release on erythrocyte contribute to hypercoagulable state in hyperuricemia
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Author：
Meishan Yan, Minghui Xu, Zhanni Li, Yao An, Zelong Wang, Shuli Li, Yingli Chen, Yanshi Xia, Liqiu Wang, Longlong Wang, Shuting Ji, Weijun Dong, Jialan Shi, Chunyan Gao
IF：
2.3720
Publish_to：
BLOOD CELLS MOLECULES AND DISEASES
PMID：
35567997
Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway
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Author：
Xing Di, Ma Yihua, Lu Miaomiao, Liu Wenlin, Zhou Hongli
IF：
2.3000
Publish_to：
BMC Nephrology
PMID：
37884904
Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells
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Author：
Zhang Mingming, Li Tianyu, Tu Zhenzhen, Zhang Yuying, Wang Xuerong, Zang Dandan, Xu Deping, Feng Yang, He Fan, Ni Mingyue, Wang Deguang, Zhou Haisheng
IF：
2.2660
Publish_to：
INTERNATIONAL UROLOGY AND NEPHROLOGY
PMID：
35396645
Heterotrimeric G protein γ subunit DEP1 is involved in hydrogen peroxide signaling and promotes aerenchyma formation in rice roots
点击查看 >>
Author：
Yun Chen, Yuanhua Chen, Yajun Zhang, Dongping Zhang, Guoming Li, Jiali Wei, Xia Hua, Bing Lv, Lijun Liu
IF：
2.2470
Publish_to：
Plant Signaling & Behavior
PMID：
33632064
Physcion Induces Hemolysis and Premature Phosphatidylserine Externalization in Human Erythrocytes
点击查看 >>
Author：
Maaged Akiel, Jawaher Alsughayyir, Ahmed M. Basudan, Hassan S. Alamri, Ayed Dera, Tlili Barhoumi, Abdullah M. Al Subayyil, Yasser S. Basmaeil, Fahad M. Aldakheel, Raid Alakeel, Hazem K. Ghneim, Yazeed A. Al-Sheikh, Yasser Alraey, Saeed Asiri, Mohammad A.
IF：
2.2330
Publish_to：
BIOLOGICAL & PHARMACEUTICAL BULLETIN
PMID：
33431739
Inhibition of ferroptosis of renal tubular cells with total flavones of Abelmoschus manihot alleviates diabetic tubulopathy
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Author：
Mei-Zi Wang, Yu-Feng Cai, Qi-Jun Fang, Ying-Lu Liu, Jie Wang, Jia-Xin Chen, Yan Fu, Bing-Ying Wan, Yue Tu, Wei Wu, Yi-Gang Wan, Geng-Lin Mu
IF：
2.2270
Publish_to：
Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
PMID：
36440653
Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective Additive
点击查看 >>
Author：
Longlong Fu, Jing Ma, Lixia Chen, Ying Guo, Wenjie Li, Xingguo Zhang, Wenhong Lu, Shusong Wang, Ying Liu
IF：
2.2000
Publish_to：
MEDICAL SCIENCE MONITOR
PMID：
38698627
Plum blossom low molecular weight polypeptide protects HaCaT cells against UVB-induced oxidative damage in vitro and underlying mechanism
点击查看 >>
Author：
Zhixiong Chen, Ping Cao, Tingheng Zhu, Cui Yan, Zhongbo Zheng, Hong Yao
IF：
2.0000
Publish_to：
SKIN RESEARCH AND TECHNOLOGY
PMID：
38282275
Resveratrol Attenuates Sepsis-Induced Cardiomyopathy in Rats through Anti-Ferroptosis via the Sirt1/Nrf2 Pathway
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Author：
Youcheng Zeng, Guodong Cao, Liang Lin, Yixin Zhang, Xiqing Luo, Xiaoyu Ma, Akelibieke Aiyisake, Qinghong Cheng
IF：
1.9720
Publish_to：
JOURNAL OF INVESTIGATIVE SURGERY
PMID：
36576230
TYMS Knockdown Suppresses Cells Proliferation, Promotes Ferroptosis via Inhibits PI3K/Akt/mTOR Signaling Pathway Activation in Triple Negative Breast Cancer
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Author：
Wang Lin, Wu Zheyi, Wang Yanyan, Chen Chunchun, Li Yulong, Dong Huiming, Yao Tingjing, Jin Gongsheng, Wang Zhenjie
IF：
1.8000
Publish_to：
CELL BIOCHEMISTRY AND BIOPHYSICS
PMID：
38961034
Perfluorooctane sulfonate causes damage to L-02 cells via Wnt/β-catenin signal path and endoplasmic reticulum stress pathway
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Author：
Cui Jiajing, Yan Shuqi, Ma Haoyan, Wang Pingwei, Liu Dongge, Liu Yanping, Chen Qianqian, Fajrin Saleh, Ren Shuping
IF：
1.7000
Publish_to：
TOXICOLOGY AND INDUSTRIAL HEALTH
PMID：
39217409
Induction of hemolysis and eryptosis by occupational pollutant nickel chloride is mediated through calcium influx and p38 MAP kinase signaling.
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Author：
Alfhili MA, Alamri HS, Alsughayyir J, Basudan AM.
IF：
1.6760
Publish_to：
Int J Occup Med Environ Health.
PMID：
34524276
The Neuroprotective Effect of Sophocarpine against Glutamate-Induced HT22 Cell Cytotoxicity
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Author：
Tong Wang, Liying Gao, Jiahua Tan, Dongzhi Zhuoma, Ruiying Yuan, Bin Li, Shan Huang
IF：
1.6000
Publish_to：
Journal of Oleo Science
PMID：
38433000
miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis
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Author：
ZhiYu Zhao, BoXia Li, DianWei Cheng, YuFang Leng
IF：
1.5000
Publish_to：
Journal of Cardiothoracic Surgery
PMID：
39815273
High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage
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Author：
Yu Lu, Yu Shifang, He Yunlei, Deng Gang, Li Qiang
IF：
0.9000
Publish_to：
Indian Journal of Hematology and Blood Transfusion
PMID：
37790743
技术问答
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你好，我想问一下如果是拍倒置荧光的话。需要分散在培养基里面还是PBS里亚?2023-06-06 11:24:48
您好，细胞分散在PBS或无血清培养基中均可。
DMSO溶解好的储存液-20度能储存多久?2022-10-10 10:43:25
您好，-20℃配制好的储备液可以保存一个月。