中文
英语
产品简介
| 中文名称 | 尼氏染色液(甲苯胺蓝法) |
| 英文名称 | Nissl Stain Solution(Toluidine Blue Method) |
| 储存条件 | RT，避光保存，有效期6个月。 |
| 规格 | 100ml |
| 单位 | 瓶 |
尼氏体(Nissl body)或称尼氏小体是分布于神经细胞胞质内的三角形或椭圆形小块状物质，能被碱性染料如硫堇、亚甲蓝、甲苯胺蓝和焦油紫等染料染红紫色到紫蓝色。
尼氏染色液(甲苯胺蓝法)主要优点是操作简便、染色稳定、适用范围广，可以用于石蜡组织切片的尼氏物质、神经元等的染色，尼氏体的存在和消失是神经细胞是否受损的重要指标，当发生脑炎、脑缺血、轴突反应等情况时，尼氏体会发生溶解甚至消失。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
小鼠脑石蜡切片
尼氏小体着紫蓝色，细胞核着淡蓝色，背景无色或浅蓝色
尼氏小体着紫蓝色，细胞核着淡蓝色，背景无色或浅蓝色
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Antibacterial Effect of Chrysanthemum Buds' Crude Extract Against Salmonella Typhimurium and Potential Application in Cooked Chicken
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Author：
Min Xing, Jiyun Yao, Yiming Guo, Ru Xin, Yaping Yu, Encong Shi, Mengdi Hao, Peng Fei, Huaibin Kang, Junliang Chen
IF：
3.7880
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Foodborne Pathogens and Disease
PMID：
35363059
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes
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Fanli Kong, Yao Zhang, Tingting Wang, Liang Zhong, Chun Feng, Yuanyuan Wu
IF：
3.6980
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EUROPEAN JOURNAL OF NEUROSCIENCE
PMID：
36440503
Neuroprotective effects of nobiletin on cerebral ischemia/reperfusion injury rats by inhibiting Rho/ROCK signaling pathway
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Dan Huang, Jiaping Qin, Na Lu, Zongjun Fu, Bo Zhang, Shuhong Tian, Qiang Liu
IF：
3.6160
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Annals of Translational Medicine
PMID：
36660614
Neural stem cell secretome exerts a protective effect on damaged neuron mitochondria in Parkinson's disease model
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Wei Ni, Jiqin Zhou, Yating Ling, Xiaorui Lu, Dongdong Niu, Yu Zeng, Yun Qiu, Yu Si, Jia Wang, Weining Zhang, Ziyu Wang, Jiabo Hu
IF：
3.6100
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BRAIN RESEARCH
PMID：
35690143
Lycium Barbarum Polysaccharides Improves Cognitive Functions in ICV-STZ-Induced Alzheimer’s Disease Mice Model by Improving the Synaptic Structural Plasticity and Regulating IRS1/PI3K/AKT Signaling Pathway
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He Yingxi, Wang Yanyou, Li Xia, Qi Yanqiang, Qu Zuwei, Hu Yanli
IF：
3.5000
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NEUROMOLECULAR MEDICINE
PMID：
38653878
Taurine ameliorates volatile organic compounds-induced cognitive impairment in young rats via suppressing oxidative stress, regulating neurotransmitter and activating NMDA receptor
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Gao Yongchao, Sun Chao, Gao Ting, Liu Zhiyong, Yang Zhao, Deng Hui, Fan Peng, Gao Junhong
IF：
3.4710
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Frontiers in Veterinary Science
PMID：
36187803
GABAB Receptor Activation Attenuates Neuronal Pyroptosis in Post-cardiac Arrest Brain Injury
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Ye Sun, Jinying Li, Haikuo Wu, Ziwei Zhao, Ting Cong, Liya Li, Xiaonan Zhang, Shengming Yin, Zhaoyang Xiao
IF：
3.3000
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NEUROSCIENCE
PMID：
37352966
Zinc finger E-Box binding homeobox 2 (ZEB2)-induced astrogliosis protected neuron from pyroptosis in cerebral ischemia and reperfusion injury
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Zhixin Zhao, Xiaoming Hu, Jie Wang, Jianfeng Wang, Yong Hou, Suyun Chen
IF：
3.2690
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Bioengineered
PMID：
34852714
NLRP3 inflammasome regulates astrocyte transformation in brain injury induced by chronic intermittent hypoxia
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Author：
She Ningning, Shi Yewen, Feng Yani, Ma Lina, Yuan Yuqi, Zhang Yitong, Cao Zine, Chen Xi, Zhao Bingjie, Liu Haiqin, Ren Xiaoyong
IF：
3.2640
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BMC NEUROSCIENCE
PMID：
36437451
Beneficial effects of Dendrobium nobile Lindl. Alkaloids (DNLA) on anxiety and depression induced by chronic unpredictable stress in rats
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Ting-Wang Xiong, Bo Liu, Qin Wu, Yun-Yan Xu, Ping Liu, Yan Wang, Jie Liu, Jing-Shan Shi
IF：
3.2520
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BRAIN RESEARCH
PMID：
34481787
The translocase of the inner mitochondrial membrane 22-2 (AtTIM22-2) is required for mitochondrial membrane functions during Arabidopsis seed development
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Author：
Wang Lifeng, Peng Guanfa, Chen Li, Guo Mingling, Wang Bingyu, Zhang Yunmeng, Zhou Jianshun, Zhong Maolin, Ye Junming
IF：
3.0000
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Frontiers in Behavioral Neuroscience
PMID：
37351155
The synergistic effect of curcumin and mitoquinol mesylate on cognitive impairment and the neuropathology of Alzheimer's disease
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Yongli Xie, Xuexia Li, Qingqing Shi, Linfeng Le, Chao Wang, Hao Xu, Guoli Wu, Xiubo Du, Zetao Chen
IF：
2.9000
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BRAIN RESEARCH
PMID：
38670478
Network pharmacology analysis and experimental validation to explore the effect and mechanism of tetramethylpyrazine for spinal cord injury
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Author：
Guodong Qi, Shujun Li, Qiong Jiang, Zhijuan Yu, Zhenggang Peng, Qiurui Li, Wei Qi, Mingjun Guo
IF：
2.8000
Publish_to：
JOURNAL OF CHEMICAL NEUROANATOMY
PMID：
38176475
miR-181c-5p suppresses neuronal pyroptosis via NLRP1 in Alzheimer’s disease
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Author：
Tingting Wang, Qionghua Long, Yang Hu, Yongli Yang, Xingguo Li, Huan Wei
IF：
2.7000
Publish_to：
BEHAVIOURAL BRAIN RESEARCH
PMID：
37003492
n-3 polyunsaturated fatty acids improve depression-like behavior by inhibiting hippocampal neuroinflammation in mice via reducing TLR4 expression
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Author：
Li Hu, Xianxiang Zeng, Kai Yang, Hongli Peng, Jinhong Chen
IF：
2.4930
Publish_to：
Immunity Inflammation and Disease
PMID：
36301036
Oscillating field stimulation promotes recovery from spinal cord injury in rats by regulating the differentiation of endogenous neural stem cells
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Author：
Chao Fang, Jian Sun, Laifu Wei, Fei Gao, Jun Qian
IF：
2.4470
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Experimental and Therapeutic Medicine
PMID：
34345261
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats
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Author：
Zhou Junjie, Zhang Chao, Fang Xu, Zhang Naixin, Zhang Xiaoxi, Zhu Zhaoqiong
IF：
2.4000
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BMC NEUROSCIENCE
PMID：
36709248
TIGAR alleviates cognitive impairment in rats with chronic cerebral hypoperfusion by suppressing oxidative stress and pyroptosis
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Jie Xiao, Min Wu, Hailong Li, Shufan Zhang, Jing Deng, Bihua Wu
IF：
1.7000
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American Journal of Translational Research
PMID：
40092124
Impaired autophagic flux in the human brain after traumatic brain injury
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Author：
Lang Jiadong, Sun Boyu, Feng Shiyao, Sun Guozhu
IF：
1.6000
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NEUROREPORT
PMID：
38526944
技术问答
（2）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
产品是否可以重复使用?2023-10-24 11:59:17
您好，可以多次使用，多次使用效果会有所降低；循环使用按照1ml/切片计算使用量同时有效期变为1个月，即100ml能在1个月内循环使用染色约100张切片。
放4度冰箱可以吗?2023-07-24 19:44:15
您好，可以的。