CAS |
No.99607-70-2 |
中文名称 |
解毒喹 |
英文名称 |
Cloquintocet-mexyl |
别名 |
解草酯 |
分子式 |
C18H22ClNO3 |
分子量 |
335.83 |
溶解性 |
Soluble in DMSO |
纯度 |
≥98% |
外观(性状) |
White to off-white Solid |
储存条件 |
Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year |
运输条件 |
冷藏运输 |
MDL |
MFCD01632329 |
SMILES |
O=C(OC(C)CCCCC)COC1=C2N=CC=CC2=C(Cl)C=C1 |
InChIKey |
COYBRKAVBMYYSF-UHFFFAOYSA-N |
InChI |
InChI=1S/C18H22ClNO3/c1-3-4-5-7-13(2)23-17(21)12-22-16-10-9-15(19)14-8-6-11-20-18(14)16/h6,8-11,13H,3-5,7,12H2,1-2H3 |
PubChem CID |
93528 |
靶点 |
Others |
通路 |
Others |
背景说明 |
Cloquintocet-mexyl是一种除草剂, 控制一年生禾本草。 |
数据来源文献 |
[1]. Said A, et al. Chloroquine promotes IL-17 production by CD4+ T cells via p38-dependent IL-23 release by monocyte-derived Langerhans-like cells. J Immunol. 2014 Dec 15;193(12):6135-43. [2]. Tuomela J, et al. Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer. Oncol Lett. 2013 Dec;6(6):1665-1672. [3]. Mohamed FE, et al. Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma. Liver Int. 2014 Jul 2. doi: 10.1111/liv.12626. [4]. Colson P, et al. Chloroquine and hydroxychloroquine as available weapons to fight COVID-19. Int J Antimicrob Agents. 2020;55(4):105932 |
规格 |
500mg |
单位 |
瓶 |