产品类型 |
多肽 |
单字母序列 |
EPPLSQEAFADLWKK |
三字母序列 |
Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys |
分子式 |
C82H123N19O24 |
分子量 |
1758.99 |
纯度 |
≥95% |
外观(性状) |
冻干粉;Lyophilized powder |
盐体系 |
TFA盐;Trifluoroacetate salt |
来源 |
合成;Synthetic |
储存条件 |
Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
背景说明 |
A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11-14 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activity DNA依赖性蛋白激酶(DNA-PK)磷酸化的底物。 DNA-PK对于修复DNA双链断裂至关重要。 该肽对应于人类p53的11–24个氨基酸,其中苏氨酸18和丝氨酸20变为丙氨酸,被用作检测DNA-PK活性的底物 |
In Vitro |
未检测 |
参考文献 |
[1] Wang, H. et al. Nucleic Acids Res. 31, 5377 (2003); [2] Srivastava, RK. et al. Clinical Cancer Res. 5, 1892 (1999); [3] Suwa, A. et al. J. Clin. Invest. 97, 1417 (1996); [4] Block, W. et al. Nucleic Acids Res. 2, 1967 (2004). |
研究领域 |
信号转导 |
规格 |
1mg 5mg 10mg |
单位 |
瓶 |
分类属性 |
目录肽 |