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产品简介
| 别名 | 梭菌肽酶 A |
| 英文名称 | CollagenaseⅡ |
| CAS | No.9001-12-1 |
| 储存条件 | -20℃，有效期2年 |
| 外观(性状) |
褐色粉末
|
| 来源 | Prepared from Cl.histolyticum |
| 酶活/效价 | ≥125units/mg solid （以实际收到的标签酶活为准） |
| 溶解性 | 5 mg/mlWater |
| 规格 | 100mg 1g |
| 单位 | 支 |
胶原酶Ⅱ适用于脂肪、肝脏，骨，甲状腺，心脏和唾液腺组织细胞的分离。
胶原蛋白酶 来源于溶组织梭菌
胶原酶Ⅱ可以用 TESCA buffer （50 mM TES，0.36 mM 氯化钙，pH 7.4，37°C）（Cat:G0150)配制成 1-2 mg/ml。 也可以用含钙镁的 PBS、含钙镁的 hanks 或不含血清的培养基配制。配完后分装，避免反复冻融。
1 个胶原消化单位（CDU）：在 pH 7.4，37℃以及钙离子存在的条件下，以每5小时从胶原中 释放的多肽相当于茚三酮显色1微摩尔亮氨酸量为一个活性单位。 1FALGPA 单位：在 pH 7.5、25℃以及钙离子存在的条件下，一个 FALGPA 水解单位每分钟 可水解 1.0µmol 呋喃基丙烯酰基-Leu-Gly-Pro-Ala。
胶原酶Ⅱ为粗品，用于分离脂肪细胞，也可以用于分离各种组织、肿瘤，尤其是上皮组织。外 观为黑棕色粉末。分子量68,000到125,000，最适PH为6.3-8.8。胶原酶能够特异性结合 -R-Pro-8-X-Gly-Pro-R-序列中的中性氨基酸（X）和甘氨酸之间的肽键。该粗品是溶组织梭菌分泌的 混合酶。主要为胶原酶、中性蛋白酶和梭菌蛋白酶。其中梭菌蛋白酶是被氧化的、最不活泼的酶， 组织的分离必须依靠胶原酶和中性蛋白酶两者共同作用。
激活剂：Ca2+，每摩尔酶需要4g钙离子激活。
抑制剂：EGTA、还原性谷胱甘肽、β-巯基乙醇、巯基乙酸钠、8-羟基喹啉、2,2'-联吡啶等。
底物：不同类型的胶原是其天然底物，而一些合成的多肽也可以作为其底物，比如： N-CBZ-gly-pro-gly-gly-pro-ala (Km = 0.71 mM)、N-CBZ-gly-pro-leu-gly-pro、N-(3-(2-furyl)acryloyl)- leu-gly-pro-ala(FALGPA)、4-Phenylazo benzyloxycarbonyl-pro-leu-gly-pro-D-arg、N-2,4-Dinitrophenyl- pro-gln-gly-ile-ala-gly-gln-D-arg。除此之外N-Succinyl-gly-pro-leu-glypro7-amido-4-methylcoumarin是 类胶原酶的肽酶的底物。N-(2,4-Dinitrophenyl)-proleu-gly-leu-trp-ala-D-arg 氨基酸化合物是脊椎动物 胶原酶的底物。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Electroacupuncture alleviates intestinal inflammation via a distinct neuro-immune signal pathway in the treatment of postoperative ileus
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Author：
Shuchang Liu, Wei Fu, Jingnan Fu, Guibing Chen, Yuxin He, Ting Zheng, Tao Ma
IF：
7.5000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38471276
Study of chondroitin sulfate E oligosaccharide as a promising complement C5 inhibitor for osteoarthritis alleviation
点击查看 >>
Author：
Chen Yu, Hengchang Zang, Cui Yang, Dong Liang, Shuang Quan, Danyang Li, Yanni Li, Qin Dong, Fengshan Wang, Lian Li
IF：
7.3280
Publish_to：
Materials Science & Engineering C-Materials for Biological Applications
PMID：
34225875
Naringin protects human nucleus pulposus cells against TNF-α-induced inflammation, oxidative stress, and loss of cellular homeostasis by enhancing autophagic flux via AMPK/SIRT1 activation
点击查看 >>
Author：
Renchang Chen, Shang Gao, Huapeng Guan, Xin Zhang, Yuliang Gao, Youxiang Su, Yun Song, Yuehua Jiang, Nianhu Li
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
35265264
Digoxin protects against intervertebral disc degeneration via TNF/NF-百B and LRP4 signaling
点击查看 >>
Author：
Qunbo Meng, Kaiwen Liu, Zhenchuan Liu, Jinbo Liu, Ziyu Tian, Shanshan Qin, Jianlu Wei, Lei Cheng
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
37790932
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1
点击查看 >>
Author：
Cheng Teng, Jingtao Wu, Zhao Zhang, Jinquan Wang, Ye Yang, Chengji Dong, Long Wu, Zhen Lin, Yuezheng Hu, Jing Wang, Xiaolei Zhang, Zhongke Lin
IF：
7.2000
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
37918392
Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells
点击查看 >>
Author：
Qianqian Jiang, Qiannan Di, Dandan Shan, Qian Xu
IF：
7.1290
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
35777343
IGF2BP3 promotes adult myocardial regeneration by stabilizing MMP3 mRNA through interaction with m6A modification
点击查看 >>
Author：
Li Simeng, Shen Siman, Xu Hao, Cai Shuyun, Yuan Xiaodong, Wang Changsen, Zhang Xiaojun, Chen Suyun, Chen Jianning, Shi De-Li, Zhang Liangqing
IF：
7.1090
Publish_to：
Cell Death Discovery
PMID：
37188676
Biological characteristics of tissue engineered-nerve grafts enhancing peripheral nerve regeneration
点击查看 >>
Author：
Li Xiangling, Xu Hang, Li Chaochao, Guan Yanjun, Liu Yuli, Zhang Tieyuan, Meng Fanqi, Cheng Haofeng, Song Xiangyu, Jia Zhibo, He Ruichao, Zhao Jinjuan, Chen Shengfeng, Guan Congcong, Yan Shi, Wang Jinpeng, Wei Yu, Zhang Jian, Tang Jinshu, Peng Jiang, Wang
IF：
7.1000
Publish_to：
Stem Cell Research & Therapy
PMID：
39020413
Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution
点击查看 >>
Author：
Chen Guanglong, Gong Ting, Wang Zhe, Wang Zeyu, Lin Xiaolin, Chen Sunrui, Sun Chu, Zhao Weijie, Kong Ye, Ai Huihan, Yang Hang, Liu Yusheng, Wu Fangyan, Kang Jiawei, Zhao Shasha, Xiao Xiuying, Sun Jing, He Aina, Li Zhi
IF：
7.0510
Publish_to：
CELLULAR ONCOLOGY
PMID：
36136268
3D printed reduced graphene oxide-GelMA hybrid hydrogel scaffolds for potential neuralized bone regeneration
点击查看 >>
Author：
Xinwei Zhang, Hao Zhang, Yi Zhang, Huimin Huangfu, Yixin Yang, Qiuyue Qin, Yidi Zhang, Yanmin Zhou
IF：
7.0000
Publish_to：
Journal of Materials Chemistry B
PMID：
36651822
Interleukin-7-loaded oncolytic adenovirus improves CAR-T cell therapy for glioblastoma
点击查看 >>
Author：
Huang Jianhan, Zheng Meijun, Zhang Zongliang, Tang Xin, Chen Yaxing, Peng Aijun, Peng Xingchen, Tong Aiping, Zhou Liangxue
IF：
6.9680
Publish_to：
CANCER IMMUNOLOGY IMMUNOTHERAPY
PMID：
33543339
Hydrogen (H2) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway
点击查看 >>
Author：
Hongwei Lu, Wei Wang, Xiaodiao Kang, Zeng Lin, Jun Pan, Shaowen Cheng, Jingdong Zhang
IF：
6.9220
Publish_to：
Journal of Inflammation Research
PMID：
33880054
Long non-coding RNA ZNFX1 antisense 1 (ZFAS1) suppresses anti-oxidative stress in chondrocytes during osteoarthritis by sponging microRNA-1323
点击查看 >>
Author：
Yanglin Gu, Guangchang Wang, Huazhong Xu
IF：
6.8320
Publish_to：
Bioengineered
PMID：
35635081
Luteolin ameliorates hypoxic pulmonary vascular remodeling in rat via upregulating KV1.5 of pulmonary artery smooth muscle cells
点击查看 >>
Author：
Zhaoxia Zhang, Ju Chen, Shanshan Su, Xin Xie, Lei Ji, Zhanqiang Li, Dianxiang Lu
IF：
6.7000
Publish_to：
PHYTOMEDICINE
PMID：
38941817
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways
点击查看 >>
Author：
Yifeng Shi, Jiaoxiang Chen, Sunlong Li, Yuhao Wu, Caiyu Yu, LiBin Ni, Jian Xiao, Zhenxuan Shao, Huanqing Zhu, Jianshun Wang, Xiangyang Wang, Xiaolei Zhang
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
35104760
Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction
点击查看 >>
Author：
Shu Jia, Tao Yang, Sheng Gao, Luyue Bai, Zhiguo Zhu, Siqi Zhao, Yexin Wang, Xiao Liang, Yanpeng Li, Longfei Gao, Zifang Zhang, Xu Gao, Dongru Li, Shang Chen, Bin Zhang, Chunyang Meng
IF：
6.6000
Publish_to：
Journal of Orthopaedic Translation
PMID：
38841339
Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota
点击查看 >>
Author：
He Ke-Jie, Dong Jia-Hui, Ouyang Xiao-Mei, Huo Ya-Ni, Cheng Xiao-Shen, Lin Ying, Li Yue, Gong Guoyu, Liu Jingjing, Ren Jian-Lin, Guleng Bayasi
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
36034889
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2
点击查看 >>
Author：
Jie Jin, Xinhuang Lv, Ben Wang, Chenghao Ren, Jingtao Jiang, Hongyu Chen, Ximiao Chen, Mingbao Gu, Zongyou Pan, Naifeng Tian, Aimin Wu, Liaojun Sun, Weiyang Gao, Xiangyang Wang, Xiaolei Zhang, Yaosen Wu, Yifei Zhou
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
34795843
A biomimetic hierarchical small intestinal submucosa–chitosan sponge/chitosan hydrogel scaffold with a micro/nano structure for dural repair
点击查看 >>
Author：
Jingxi Wang, Kun Li, Junwei Xu, Meili Liu, Ping Li, Xiaoming Li, Yubo Fan
IF：
6.3310
Publish_to：
Journal of Materials Chemistry B
PMID：
34586141
HMG20A Inhibit Adipogenesis by Transcriptional and Epigenetic Regulation of MEF2C Expression
点击查看 >>
Author：
Ruixiao Li, Shan Meng, Mengting Ji, Xiaoyin Rong, Ziwei You, Chunbo Cai, Xiaohong Guo, Chang Lu, Guoming Liang, Guoqing Cao, Bugao Li, Yang Yang
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36142473
Inhibition of Sema4D attenuates pressure overload-induced pathological myocardial hypertrophy via the MAPK/NF-κB/NLRP3 pathways
点击查看 >>
Author：
Bing Wu, Cheng Xu, Changwu Xu, Liqiang Qiu, Ji-Xian Gao, Ming Li, Yuanguo Xiong, Hao Xia, Zhongyuan Xia, Xiaoxiong Liu
IF：
6.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
37952827
Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p
点击查看 >>
Author：
Yin Zhuang, Sheng Song, Dan Xiao, Xueguang Liu, Xiaofei Han, Shihao Du, Yuan Li, Yanming He, Shujun Zhang
IF：
6.1130
Publish_to：
Frontiers in Molecular Biosciences
PMID：
35111808
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice
点击查看 >>
Author：
Mengjing Wu, Chuan Chen, Hehua Lei, Zheng Cao, Cui Zhang, Ruichen Du, Ce Zhang, Yuchen Song, Mengyu Qin, Jinlin Zhou, Yujing Lu, Xian Wang, Limin Zhang
IF：
6.1000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
37852299
Cholesterol Induces Pyroptosis and Matrix Degradation via mSREBP1-Driven Endoplasmic Reticulum Stress in Intervertebral Disc Degeneration
点击查看 >>
Author：
Yan Jiansen, Li Shuangxing, Zhang Yangyang, Deng Zhihuai, Wu Jiajun, Huang Zhengqi, Qin Tianyu, Xiao Yin, Zhou Jie, Xu Kang, Ye Wei
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
35174163
Patient-derived organoids as a platform for drug screening in metastatic colorectal cancer
点击查看 >>
Author：
Xingfeng He, Yan Jiang, Long Zhang, Yaqi Li, Xiang Hu, Guoqiang Hua, Sanjun Cai, Shaobo Mo, Junjie Peng
IF：
6.0640
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
37284236
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation
点击查看 >>
Author：
Chuan Chen, Mengjing Wu, Hehua Lei, Zheng Cao, Fang Wu, Yuchen Song, Ce Zhang, Mengyu Qin, Cui Zhang, Ruichen Du, Jinlin Zhou, Yujing Lu, Denghui Xie, Limin Zhang
IF：
6.0000
Publish_to：
ACS Pharmacology & Translational Science
PMID：
36798476
The Protective Effect of Evodiamine in Osteoarthritis: An In Vitro and In Vivo Study in Mice Model
点击查看 >>
Author：
Shuyuan Xian, Zeng Lin, Chao Zhou, Xing Wu
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35795554
Single-cell RNA-Seq analysis of diabetic wound macrophages in STZ-induced mice
点击查看 >>
Author：
Ma Jiaxu, Song Ru, Liu Chunyan, Cao Guoqi, Zhang Guang, Wu Zhenjie, Zhang Huayu, Sun Rui, Chen Aoyu, Wang Yibing, Yin Siyuan
IF：
5.9080
Publish_to：
Journal of Cell Communication and Signaling
PMID：
36445632
L-Theanine Modulates Intestine-Specific Immunity by Regulating the Differentiation of CD4+ T Cells in Ovalbumin-Sensitized Mice
点击查看 >>
Author：
Qing-Yun Qu, Xian-Ying Song, Ling Lin, Zhi-Hua Gong, Wei Xu, Wen-Jun Xiao
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
36394825
The interdependent relationship between the nitric oxide signaling pathway and primary cilia in pulse electromagnetic field-stimulated osteoblastic differentiation
点击查看 >>
Author：
Wen-Fang He, Rong Qin, Yu-Hai Gao, Jian Zhou, Juan-Juan Wei, Jing Liu, Xue-Feng Hou, Hui-Ping Ma, Cory J. Xian, Xue-Yan Li, Ke-Ming Chen
IF：
5.8340
Publish_to：
FASEB JOURNAL
PMID：
35616355
Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway
点击查看 >>
Author：
Zhou Wenxian, Shi Yifeng, Wang Hui, Yu Caiyu, Zhu Huanqing, Wu Aimin
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34335275
Mitochondrial glycerol 3-phosphate dehydrogenase deficiency exacerbates lipotoxic cardiomyopathy
点击查看 >>
Author：
Hua Qu, Xiufei Liu, Jiaran Zhu, Niexia He, Qingshan He, Linlin Zhang, Yuren Wang, Xiaoli Gong, Xin Xiong, Jinbo Liu, Chuan Wang, Gangyi Yang, Qingwu Yang, Gang Luo, Zhiming Zhu, Yi Zheng, Hongting Zheng
IF：
5.8000
Publish_to：
iScience
PMID：
38832016
Molecular Biomarker of Drug Resistance Developed From Patient-Derived Organoids Predicts Survival of Colorectal Cancer Patients
点击查看 >>
Author：
Lifeng Chen, Bo Tian, Wen Liu, Haitao Liang, Yong You, Weizhen Liu
IF：
5.7380
Publish_to：
Frontiers in Oncology
PMID：
35425715
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway
点击查看 >>
Author：
Qi Guo, Meng Zhang, Yonghui Dong, Ke Liu, Desheng Wang, Jia Zheng
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37087870
Inhibition of tartrate-resistant acid phosphatase 5 can prevent cardiac fibrosis after myocardial infarction
点击查看 >>
Author：
Yang Shujun, Pei Liying, Huang Zijie, Zhong Yinsheng, Li Jun, Hong Yinghui, Long Huibao, Chen Xuxiang, Zhou Changqing, Zheng Guanghui, Zeng Chaotao, Wu Haidong, Wang Tong
IF：
5.7000
Publish_to：
MOLECULAR MEDICINE
PMID：
38879488
Characterization of a Human Gastrointestinal Stromal Tumor Cell Line Established by SV40LT-Mediated Immortalization
点击查看 >>
Author：
Xiangchen Hu, Peng Su, Bo Liu, Jingwei Guo, Zitong Wang, Cai He, Zhe Wang, Youwei Kou
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
37686448
Differences in chemotaxis of human mesenchymal stem cells and cervical cancer cells
点击查看 >>
Author：
Song Yizuo, Li Ruyi, Ye Miaomiao, Pan Chunyu, Zheng Lihong, Wang Zhi-wei, Zhu Xueqiong
IF：
5.5610
Publish_to：
APOPTOSIS
PMID：
35849265
Endothelial Progenitor Cell-Derived Microvesicles Promote Angiogenesis in Rat Brain Microvascular Endothelial Cells In vitro
点击查看 >>
Author：
Zeng Wen, Lei Qiaoling, Ma Jiao, Gao Shuqiang, Ju Rong
IF：
5.5050
Publish_to：
Frontiers in Cellular Neuroscience
PMID：
33679329
Low-level Nd:YAG laser inhibiting inflammation and oxidative stress in human gingival fibroblasts via AMPK/SIRT3 axis
点击查看 >>
Author：
Haizheng Zhang, Chenyi Zhang, Lai Pan, Yifan Chen, Zirui Bian, Yuxuan Yang, Ting Ke, Weilian Sun, Lili Chen, Jingyi Tan
IF：
5.4000
Publish_to：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
PMID：
38244301
Comparison of visceral fat lipolysis adaptation to high-intensity interval training in obesity-prone and obesity-resistant rats
点击查看 >>
Author：
Liu Yang, Li Yu, Cheng Baishuo, Feng Shige, Zhu Xiangui, Chen Wei, Zhang Haifeng
IF：
5.3950
Publish_to：
Diabetology & Metabolic Syndrome
PMID：
35501906
Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold
点击查看 >>
Author：
Bing-Yu Zhang, Pu Xu, Qing Luo, Guan-Bin Song
IF：
5.3260
Publish_to：
World Journal of Stem Cells
PMID：
33584983
Foxo1-induced miR-92b down-regulation promotes blood-brain barrier damage after ischaemic stroke by targeting NOX4
点击查看 >>
Author：
Jian Shen, Ganglei Li, Yu Zhu, Qingsheng Xu, Hengjun Zhou, Kangli Xu, Kaiyuan Huang, Renya Zhan, Jianwei Pan
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
33955666
Piezo1 transforms mechanical stress into pro senescence signals and promotes osteoarthritis severity
点击查看 >>
Author：
Yikai Liu, Zian Zhang, Jun Li, Bingying Chang, Qingbo Lin, Fengyu Wang, Wenzhe Wang, Haining Zhang
IF：
5.3000
Publish_to：
MECHANISMS OF AGEING AND DEVELOPMENT
PMID：
37839614
Protection of primary cilia is an effective countermeasure against the impairment of osteoblast function induced by simulated microgravity
点击查看 >>
Author：
Jing Liu, Fei-Fan Leng, Yu-Hai Gao, Wen-Fang He, Ju-Fang Wang, Cory J. Xian, Hui-Ping Ma, Ke-Ming Chen
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
36512344
Lactobacillus acidophilus and its metabolite ursodeoxycholic acid ameliorate ulcerative colitis by promoting Treg differentiation and inhibiting M1 macrophage polarization
点击查看 >>
Author：
Song Deng, Chaoying Pei, Kaiwei Cai, Wenyi Huang, Xiaoyi Xiao, Xingyuan Zhang, Rongyao Liang, Yanlong Chen, Zhiyong Xie, Pei Li, Qiongfeng Liao
IF：
5.2000
Publish_to：
Frontiers in Microbiology
PMID：
38292253
Tiao-bu-fei-shen formula promotes downregulation of the caveolin 1-p38 mapk signaling pathway in COPD - Associated tracheobronchomalacia cell model
点击查看 >>
Author：
Pengcheng Zhou, Wei Yu, Chuantao Zhang, Keling Chen, Wenjun Tang, Xuelian Li, Zijun Liu, Qianming Xia
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
35367574
Casticin ameliorates osteoarthritic cartilage damage in rats through PI3K/AKT/HIF-1α signaling
点击查看 >>
Author：
Deren Liu, Wei Mei, Junfeng Kang, Taiyang Liao, Yibao Wei, Lishi Jie, Lei Shi, Peimin Wang, Jun Mao, Peng Wu
IF：
5.1000
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
38309612
Fisetin suppresses ferroptosis through Nrf2 and attenuates intervertebral disc degeneration in rats
点击查看 >>
Author：
Chenchao Li, Yekai Zhang, Yuxin Deng, Yu Chen, Chenyu Wu, Xiaoying Zhao, Ximiao Chen, Xiangyang Wang, Yifei Zhou, Xiaolei Zhang, Naifeng Tian
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38145645
The role of SK3 in progesterone-induced inhibition of human fallopian tubal contraction
点击查看 >>
Author：
Zhang Duo, Zhu Qian, Xia Wei, Zhu Chenfeng, Zhao Xiaoya, Zhang Yiqin, He Chuqing, Ji Sifan, Li Xiaocui, Zhang Jian
IF：
4.9820
Publish_to：
Reproductive Biology and Endocrinology
PMID：
35488306
Elastic modulus of hydrogel regulates osteogenic differentiation via liquid–liquid phase separation of YAP
点击查看 >>
Author：
Kuang Tan, Qiaolin Yang, Yineng Han, Ziyao Zhuang, Yi Zhao, KunYao Guo, Anqi Tan, Yunfei Zheng, Weiran Li
IF：
4.9000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
37494632
Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway
点击查看 >>
Author：
Jia Wu, Haoliang Li, Fei Hu, Peng Luo
IF：
4.8890
Publish_to：
Journal of Orthopaedic Translation
PMID：
36439628
Berberine Ameliorates Obesity by Inducing GDF15 Secretion by Brown Adipocytes
点击查看 >>
Author：
Li Chang, Leng Qingyang, Li Lihua, Hu Fan, Xu Yuejie, Gong Sa, Yang Ying, Zhang Hongli, Li Xiaohua
IF：
4.8000
Publish_to：
ENDOCRINOLOGY
PMID：
36825874
MgO@SiO2 Nanocapsules： A Controlled Magnesium Ion Release System for Targeted Inhibition of Osteoarthritis Progression
点击查看 >>
Author：
Na Liu, Fangchao JIANG, Zhizi FENG, Sen MEI, Yingna Cui, Yu ZHENG, Wei Yang, Benjie WANG, Weizhong ZHANG, Jin Xie, Nan Zhang
IF：
4.6000
Publish_to：
Nanoscale Advances
PMID：
39911730
A Subpopulation of Schwann Cell-Like Cells With Nerve Regeneration Signatures Is Identified Through Single-Cell RNA Sequencing
点击查看 >>
Author：
Wei Zairong, Shu Shenyou, Zhang Mingjun, Xie Sitian, Tang Shijie, Nie Kaiyu, Li Haihong
IF：
4.5660
Publish_to：
Frontiers in Physiology
PMID：
34093220
ZEB2, interacting with MDM2, contributes to the dysfuntion of brain microvascular endothelial cells and brain injury after intracerebral hemorrhage
点击查看 >>
Author：
Qingbao Guo, Manli Xie, Miao Guo, Feiping Yan, Lihong Li, Rui Liu
IF：
4.5340
Publish_to：
CELL CYCLE
PMID：
34334113
Sinomenine Ameliorates IL-1汕-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-百B Signaling Pathways
点击查看 >>
Author：
Gongbiao Lu, Cunxin Zhang, Kang Li, Kai Gao, Maoqing Fu, Chaoliang Lyu, Zhengxue Quan
IF：
4.5000
Publish_to：
Journal of Inflammation Research
PMID：
37881650
Co-immunizing with HMGB1 enhances anti-tumor immunity of B7H3 vaccine in renal carcinoma
点击查看 >>
Author：
Huanyou Sun, Juan Li, Wenwen Hu, Yinan Yan, Zengli Guo, Zichun Zhang, Yuxin Chen, Xuefan Yao, Ling Teng, Xinyuan Wang, Liantao Li, Dafei Chai, Junnian Zheng, Gang Wang
IF：
4.4070
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
34560414
ER-β accelerates the process of primary osteoporosis by promoting VEGFA-mediated apoptosis of osteoblasts
点击查看 >>
Author：
Zhujie Xu, Peng Wang, Zhenyu Wang, Hao Cui, Tianshu Gao, Zhenting Wang, Yi Liu
IF：
4.4000
Publish_to：
GENOMICS
PMID：
37967683
Stiffness of the extracellular matrix affects apoptosis of nucleus pulposus cells by regulating the cytoskeleton and activating the TRPV2 channel protein
点击查看 >>
Author：
Zhao-Hui Yu, Yi-Chao Ji, Kun Li, Ting Liang, Bo Liu, Hai-Lei Chen, Li Ni, Zong-Ping Luo, Hui-Lin Yang
IF：
4.3150
Publish_to：
CELLULAR SIGNALLING
PMID：
33862152
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system
点击查看 >>
Author：
Wei Fu, Chao Dai, Zifeng Ma, Qiao Li, Daoliang Lan, Changpo Sun, Xin Wu, Jian Li, Shujin Wang
IF：
4.3000
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
38272172
Decidual stromal cells-derived exosomes incurred insufficient migration and invasion of trophoblast by disturbing of β-TrCP-mediated snail ubiquitination and degradation in unexplained recurrent spontaneous abortion
点击查看 >>
Author：
Xiong Miao, Wang Qiaohong, Zhang Xiaoxin, Wen Liping, Zhao Aimin
IF：
4.2000
Publish_to：
EUROPEAN JOURNAL OF MEDICAL RESEARCH
PMID：
38195659
EMT status of circulating breast cancer cells and impact of fluidic shear stress
点击查看 >>
Author：
Yanling Jin, Wei Cai, Chanyuan Zhao, Feng Yang, Chenguang Yang, Xiaoyu Zhang, Quan Zhou, Wenjie Zhao, Chenli Zhang, Fangfang Zhang, Min Wang, Min Li
IF：
4.1450
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
36228736
Tendon Stem/Progenitor Cell-Laden Nanofiber Hydrogel Enhanced Functional Repair of Patellar Tendon
点击查看 >>
Author：
Hongrui Zhang, Yike Dai, Huibin Long, Ruiqi Cao, Lin Shi, Jiaming Zhao, Lifeng Ma, Naicheng Diao, Heyong Yin, Ai Guo
IF：
4.1000
Publish_to：
Tissue Engineering Part A
PMID：
36424823
Effect of Angelica Sinensis extract on the angiogenesis of preovulatory follicles (F1–F3) in late-phase laying hens
点击查看 >>
Author：
Zhenlei Ping, Xin Chen, Lixue Fang, Kai Wu, Chang Liu, Hao Chen, Xiaowen Jiang, Jun Ma, Wenhui Yu
IF：
4.0140
Publish_to：
POULTRY SCIENCE
PMID：
36566660
Oxymatrine combined with rapamycin to attenuate acute cardiac allograft rejection
点击查看 >>
Author：
Xu Lan, Jingyi Zhang, Shaohua Ren, Hongda Wang, Bo Shao, Yafei Qin, Hong Qin, Chenglu Sun, Yanglin Zhu, Guangming Li, Hao Wang
IF：
4.0000
Publish_to：
Heliyon
PMID：
38655317
TSH upregulates CYP4B1 through the PI3K/AKT/CREB pathway to promote cardiac hypertrophy
点击查看 >>
Author：
Han Ziqi, Dong Qianqian, Lu Xiao, Liu Shanshan, Yang Yanlong, Shao Feifei, Tian Limin
IF：
3.9000
Publish_to：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
PMID：
40056338
BMP2 is required for granulosa cell proliferation and primordial follicle activation in chicken
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Author：
Xiaotong Guo, Xuzhao Wang, Jiahui Wei, Yuxiao Ma, Feiyi Wang, Qing Sun, Hongcai Sun, Guiyu Zhu
IF：
3.8000
Publish_to：
POULTRY SCIENCE
PMID：
39731872
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells
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Author：
Wang Rui, Shi Zhaoguo, Li Jinlu, Tang Defu, Qin Shizhen, Guo Yanli
IF：
3.7380
Publish_to：
BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
34779997
Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells
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Author：
Renye Que, Mengxing Cao, Yancheng Dai, Yi Zhou, Yirong Chen, Liubing Lin
IF：
3.7300
Publish_to：
Biochemistry and Cell Biology
PMID：
35785548
Nrf2/HO-1 pathway is involved the anti-inflammatory action of intrauterine infusion of platelet-rich plasma against lipopolysaccharides in endometritis
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Author：
Peng Zhang, Dan Li, Zongzhi Yang, Pingping Xue, Xiaoqiang Liu
IF：
3.7120
Publish_to：
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
PMID：
34979839
Fucoxanthin inhibits cardiac fibroblast transdifferentiation by alleviating oxidative stress through downregulation of BRD4
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Author：
Jinxia Han, Yanfang Zhang, Haisheng Peng
IF：
3.7000
Publish_to：
PLoS One
PMID：
37699016
Early Growth Response Protein 1 Knockdown Alleviates the Cerebral Injury in Rats with Intracerebral Hemorrhage via STAT3/NF-κB Pathway by Reducing RXRα Acetylation Level
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Author：
Lijuan Xie, Yingying Wang, Zhuo Chen
IF：
3.5900
Publish_to：
NEUROSCIENCE
PMID：
33600884
Synergistic effects of MFG-E8 and whey protein on mitigating D-galactose-induced sarcopenia through PI3K/AKT/PGC-1汐 and MAPK/ERK signaling pathways
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Author：
He Li, Kaifang Guan, Rongchun Wang, Aihua Zhu, Ying Ma
IF：
3.5000
Publish_to：
JOURNAL OF DAIRY SCIENCE
PMID：
37678791
A polymorphism in porcine miR-22 is associated with pork color
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Author：
Wang Han, Shen Zhonghao, Huang Ruihua, Zhao Ayong, Jiang Jiani, Li Pinghua, Zhou Xiaolong, Yang Songbai, Hou Liming
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
35968001
Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy
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Author：
Shuwen Zhang, Weidong Liang, Yakefu Abulizi, Tao Xu, Rui Cao, Chuanhui Xun, Jian Zhang, Weibin Sheng
IF：
3.4110
Publish_to：
Biomed Research International
PMID：
34055990
A study of the role of multiple layer-by-layer assembled bionic extracellular matrix in promoting wound healing via activation of the Wnt signaling pathway
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Author：
Zehui Wang, Kun Cao, Di Yan, Yangjing Ge, Ruiyuan Li, Yanwen Liu, Ting Ma, Xiaojuan Sun
IF：
3.4000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
PMID：
36633398
miR-26a-5p Regulates Adipocyte Differentiation via Directly Targeting ACSL3 in Adipocytes
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Author：
Ning Ding, Wenwen Wang, Jun Teng, Yongqing Zeng, Qin Zhang, Licai Dong, Hui Tang
IF：
3.3000
Publish_to：
Adipocyte
PMID：
36710425
Methamphetamine exposure increases cardiac microvascular permeability by activating the VEGF-PI3K-Akt-eNOS signaling pathway, reversed by Bevacizumab.
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Author：
Chen R, Huang P, Wei S, Zhang C, Lai X, Wang H, Tang J
IF：
3.2470
Publish_to：
HUMAN & EXPERIMENTAL TOXICOLOGY
PMID：
35975811
Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model
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Author：
Wu Lingqin, Yin Wenhui, Wen Jutai, Wang Shuying, Li Huihui, Wang Xiaoli, Zhang Weixiao, Duan Shuyao, Zhu Qiuyu, Gao Erhe, Wu Shili, Zhan Bin, Zhou Rui, Yang Xiaodi
IF：
3.2000
Publish_to：
Parasites & Vectors
PMID：
37845695
Transcriptomic analysis and biological evaluation reveals that LMO3 regulates the osteogenic differentiation of human adipose derived stem cells via PI3K/Akt signaling pathway
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Author：
Kang Yue, Pei Wenye
IF：
3.1560
Publish_to：
JOURNAL OF MOLECULAR HISTOLOGY
PMID：
35165791
Abaloparatide and teriparatide enhance mandibular growth in adolescent rats with site-specific and mechano-related effects
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Author：
Wang Ruyi, Qiao Hui, Qian Yuran, Zhen Gehua, Zhao Zhihe, Li Yu
IF：
3.1310
Publish_to：
EUROPEAN JOURNAL OF ORTHODONTICS
PMID：
36576115
Piezo1 involves in intracellular osteogenic transformation signal to promote the ossification of ligamentum flavum
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Author：
Tong Tong, Feng Wang, Dechao Miao, Linfeng Wang
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
37104881
Endothelin-1 potentiated constriction in preeclampsia placental veins: role of ETAR/ETBR/CaV1.2/CALD1
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Author：
Hongyu Su, Min Li, Na Li, Yingying Zhang, Yun He, Ze Zhang, Yumeng Zhang, Qinqin Gao, Zhice Xu, Jiaqi Tang
IF：
3.0000
Publish_to：
PLACENTA
PMID：
39476475
MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments
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Author：
Minde Li, Lin Zhou, Shaoyang Li, Linchun Fang, Le Yang, Xiao Wu, Chenxing Yang, Youyuan Bao, Sihai Lan, Zhigao Tong, Suyue Zheng, Bin Tang, Erming Zeng, Shenhao Xie, Cheng Chen, Tao Hong
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
34084216
Circ_0110251 overexpression alleviates IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation by regulating miR-3189-3p/SPRY1 axis in osteoarthritis
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Author：
Yawei Zhang, Hengheng Zheng, Baitong Li
IF：
2.9570
Publish_to：
AUTOIMMUNITY
PMID：
35196925
Interleukin‑Iβ promotes cartilage degeneration by regulating forkhead box protein O4 and type Ⅱ collagen
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Author：
Jianxiong Wu, Hongjun Zhang, Rulin Deng, Lifeng Xing, Mingwu Hu, Xiaoling Fu
IF：
2.9520
Publish_to：
Molecular Medicine Reports
PMID：
34549304
Follicular fluid exosomes regulate oxidative stress resistance, proliferation, and steroid synthesis in porcine theca cells
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Author：
Chenfeng Yuan, Xue Chen, Caomeihui Shen, Lu Chen, Yun Zhao, Xin Wang, Maosheng Cao, Zijiao Zhao, Tong Chen, Boqi Zhang, Tariq Iqbal, Chunjin Li, Xu Zhou
IF：
2.9230
Publish_to：
THERIOGENOLOGY
PMID：
36209547
Paeoniflorin, the Main Monomer Component of Paeonia lactiflora, Exhibits Anti-inflammatory Properties in Osteoarthritis Synovial Inflammation
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Author：
Chen Pu, Zhou Jun, Ruan An-min, Ma Yu-feng, Wang Qing-fu
IF：
2.9000
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
37999887
Enhancement of the chondrogenic differentiation of mesenchymal stem cells and cartilage repair by ghrelin
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Author：
Litong Fan Jiaqing Chen Yanmeng Tao Boon Chin H
IF：
2.8000
Publish_to：
Wiley Online Library
PMID：
30644571
Antioxidant monoammonium glycyrrhizinate alleviates damage from oxidative stress in perinatal cows
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Author：
Cai Zhang, Chenxu Li, Qi Shao, Sudan Meng, Xueying Wang, Tao Kong, Yu Li
IF：
2.7180
Publish_to：
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
PMID：
35989475
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway
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Author：
Yan Gao, Sixiang Wang, Yuehong Gao, Li Yang
IF：
2.7000
Publish_to：
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
PMID：
39434543
Tendon stem/progenitor cells are promising reparative cell sources for multiple musculoskeletal injuries of concomitant articular cartilage lesions associated with ligament injuries
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Author：
Yin Heyong, Mao Kelei, Huang Yufu, Guo Ai, Shi Lin
IF：
2.6000
Publish_to：
Journal of Orthopaedic Surgery and Research
PMID：
37968672
Polysaccharide from alfalfa activates RAW 264.7 macrophages through MAPK and NF- B signaling pathways
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Author：
Y Xie, L Wang, H Sun, Y Wang, Z Yang, G Zhang
IF：
2.5960
Publish_to：
International journal of Biological Macromolecules
PMID：
30590152
MiR-128-1-5p regulates differentiation of ovine stromal vascular fraction by targeting the KLF11 5′-UTR
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Author：
Jianhua Liu, Yu Liang, Liying Qiao, Dong Xia, Yangyang Pan, Wenzhong Liu
IF：
2.5660
Publish_to：
DOMESTIC ANIMAL ENDOCRINOLOGY
PMID：
35338828
Resolvin D1 inhibits the proliferation of osteoarthritis fibroblast-like synoviocytes through the Hippo-YAP signaling pathway
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Author：
Su Siwei, Jiang Wenjun, Wang Xiaoying, Du Sen, Qi Jianhong, Jia Qingwei, Song Hongqiang
IF：
2.5620
Publish_to：
BMC MUSCULOSKELETAL DISORDERS
PMID：
35168589
Piezo1 promotes peripheral nerve fibrotic scar formation through Schwann cell senescence
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Author：
Jing Liang, Nan Zhang, Ge Li, Xiang Zhou, Zhe Li, Zhaoying Zhan, Jingyuan Fan, Canbin Zheng, Qingtang Zhu, Jian Qi, Liwei Yan
IF：
2.5000
Publish_to：
NEUROSCIENCE LETTERS
PMID：
39059459
Hydroxysafflor yellow A attenuates oxidative stress injury‑induced apoptosis in the nucleus pulposus cell line and regulates extracellular matrix balance via CA XII
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Author：
Shuo Yang, Wenbo Liao
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
35069863
CircRNA-5335 Regulates the Differentiation and Proliferation of Sheep Preadipocyte via the miR-125a-3p/STAT3 Pathway
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Author：
Wei Guo, Renzeng Ciwang, Lei Wang, Shuer Zhang, Nan Liu, Jinshan Zhao, Lisheng Zhou, Hegang Li, Xiaoxiao Gao, Jianning He
IF：
2.4000
Publish_to：
Veterinary Sciences
PMID：
38393088
Transcriptomics analysis of Daheng broilers reveals that PLIN2 regulates chicken preadipocyte proliferation, differentiation and apoptosis
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Author：
Li Jingjing, Yang Chaowu, Ren Peng, Lin Zhongzhen, Zhang Donghao, Jiang Xiaosong, Wang Li, Liu Yiping
IF：
2.3160
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
34716501
Metformin Inhibits the Estrogen-mediated Epithelial-Mesenchymal Transition of Ectopic Endometrial Stromal Cells in Endometriosis
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Author：
YUNKAI XIE, WEIMIN KONG, XIAOLING ZHAO, DAN LUO, SHUNING CHEN, HE ZHANG, YULIANG RAN
IF：
2.3000
Publish_to：
IN VIVO
PMID：
37905623
Fowl adenovirus serotype 4 (FAdV-4) infection induces inflammatory responses in chicken embryonic cardiac fibroblasts via PI3K/Akt and IκBα/NF-κB signaling pathways
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Author：
Xiaoao Feng, Dejing Yin, Tian Fang, Chao Zhao, Jun Yue, Erpeng Zhu, Zhentao Cheng
IF：
2.2000
Publish_to：
RESEARCH IN VETERINARY SCIENCE
PMID：
38968647
Isolation, identification, and induced differentiation of satellite cells from skeletal muscle of adult tree shrews
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Author：
Ke Shenghui, Feng Yiwei, Luo Liying, Qin Wanzhao, Liu Huayu, Nie Jingchong, Liang Beijiang, Ma Hongjie, Xie Mao, Li Jingyu, Niu Zhijie, Li Guojian, Tang Anzhou, Xia Wei, He Guangyao
IF：
2.1000
Publish_to：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
PMID：
38127228
Long noncoding RNA ZFAS1 suppresses chondrocytes apoptosis via miR-302d-3p/SMAD2 in osteoarthritis
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Author：
Li Jian, Liu Mingting, Li Xianrang, Shi Hui, Sun Shui
IF：
2.0430
Publish_to：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
PMID：
33686420
Quercetin Alleviates Hyperglycemic-Generated Endoplasmic Reticulum Stress-Contacted Apoptosis of Rat Nucleus Pulposus Cells
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Author：
Zhen Yu, Xianfeng Wang, Yusen Hu, Xinfa Wang, Zhenghuan Zhu, Xu Xu, Yiming Wang, Ailiang Zhang
IF：
1.9000
Publish_to：
Balkan Medical Journal
PMID：
39757454
Melatonin protects sheep endometrial epithelial cells against lipopolysaccharide-induced inflammation in vitro
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Author：
Wenbo Ge, Hongwei Duan, Jianling Zeng, Xingxu Zhao, Jianyong Li, Junjie Hu
IF：
1.8580
Publish_to：
REPRODUCTION IN DOMESTIC ANIMALS
PMID：
36018566
Liraglutide inhibits AngII-induced cardiac fibroblast proliferation and ECM deposition through regulating miR-21/PTEN/PI3K pathway
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Author：
Wang Jun, Guo Run, Ma Xiaoli, Wang Ying, Zhang Qianyu, Zheng Nan, Zhang Jun, Li Chenchen
IF：
1.7520
Publish_to：
CELL AND TISSUE BANKING
PMID：
35792987
miR-301a inhibits adipogenic differentiation of adipose-derived stromal vascular fractions by targeting HOXC8 in sheep
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Author：
Bishi Zhao, Yangyang Pan, Liying Qiao, Jianhua Liu, Kaijie Yang, Yu Liang, Wenzhong Liu
IF：
1.7490
Publish_to：
ANIMAL SCIENCE JOURNAL
PMID：
34856652
Low-Intensity Nanosecond Pulsed Electric Field Accelerates Osteogenic Transformation of Human Dermal Fibroblasts by Enhancing Cell Pluripotency
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Author：
Jingtian Lai, Zewei Wang, Haiying Zhou, Pengfei Li, Hui Lu, Tian Tu
IF：
1.6000
Publish_to：
Cellular Reprogramming
PMID：
38011697
Decellularized nerve extracellular matrix/chitosan crosslinked by genipin to prepare a moldable nerve repair material
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Author：
Zhang Fangsong, Zhang Naili, Xu Qing, Zhang Luping, Zhang Chunlei, Liu Hongfu, Yu Zhenhai, Zhou Shuai, Feng Guoying, Huang Fei
IF：
1.5220
Publish_to：
CELL AND TISSUE BANKING
PMID：
34115245
技术问答
（15）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
需要避光保存吗?2023-09-02 16:10:05
您好，不需要避光保存。
可以用纯水配制么?2023-08-22 08:37:52
您好，可以用水溶解，参考溶解性5mg/ml。
配成溶液后-20℃可以保存多久?2023-07-18 17:42:29
您好，暂时没有验证过配成溶液后具体能保存多久，但建议配置后分装保存，避免反复冻融。
可以用于人组织的消化吗?2023-05-28 19:54:40
您好，可以用于人的组织消化，胶原酶Ⅱ主要适用于脂肪、肝脏，骨，甲状腺，心脏和唾液腺组织细胞的分离。
可以溶解纤维蛋白多聚体吗?2023-05-05 22:16:33
您好，我司暂时未做过实际验证，如果您有文献支持可以试一下。