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产品简介
| 别名 | 梭菌肽酶 A |
| 英文名称 | CollagenaseⅠ |
| CAS | No.9001-12-1 |
| 储存条件 | -20℃，有效期2年 |
| 外观(性状) |
褐色结晶性粉末
|
| 来源 | Collagenase from Clostridium histolyticum |
| 酶活/效价 | ≥125units/mg solid （以实际收到的标签酶活为准） |
| 规格 | 100mg 1g |
| 单位 | 支 |
胶原酶Ⅰ用于上皮、肺和肾上腺组织细胞的分离
胶原蛋白酶 来源于溶组织梭菌
胶原酶Ⅰ可以用 TESCA buffer （50 mM TES，0.36 mM 氯化钙，pH 7.4，37°C）（Cat:G0150)配制成 1-2 mg/ml。 也可以用含钙镁的 PBS、含钙镁的 hanks 或不含血清的培养基配制。配完后分装，避免反复冻融。
1 个胶原消化单位（CDU）：在 pH 7.4，37℃以及钙离子存在的条件下，以每5小时从胶原中 释放的多肽相当于茚三酮显色1微摩尔亮氨酸量为一个活性单位。
1FALGPA 单位：在 pH 7.5、25℃以及钙离子存在的条件下，一个 FALGPA 水解单位每分钟 可水解 1.0μmol 呋喃基丙烯酰基-Leu-Gly-Pro-Ala。
胶原酶Ⅰ为粗品，用于上皮、肺和肾上腺组织细胞的分离。外观为黑棕色粉末。分子量68,000 到125,000，最适PH为6.3-8.8。胶原酶能够特异性结合-R-Pro-8-X-Gly-Pro-R-序列中的中性氨基酸（X） 和甘氨酸之间的肽键。该粗品是溶组织梭菌分泌的混合酶。主要为胶原酶、中性蛋白酶和梭菌蛋白 酶。其中梭菌蛋白酶是被氧化的、最不活泼的酶，组织的分离必须依靠胶原酶和中性蛋白酶两者共 同作用。
激活剂：Ca2+，最适合浓度为5 mM。
抑制剂：EGTA、还原性谷胱甘肽、β-巯基乙醇、巯基乙酸钠、8-羟基喹啉、2,2'-联吡啶等。
底物：不同类型的胶原是其天然底物，而一些合成的多肽也可以作为其底物，比如： N-CBZ-gly-pro-gly-gly-pro-ala (Km = 0.71 mM)、N-CBZ-gly-pro-leu-gly-pro、N-(3-(2-furyl)acryloyl)- leu-gly-pro-ala(FALGPA)、4-Phenylazo benzyloxycarbonyl-pro-leu-gly-pro-D-arg、N-2,4-Dinitrophenyl- pro-gln-gly-ile-ala-gly-gln-D-arg。除此之外N-Succinyl-gly-pro-leu-glypro7-amido-4-methylcoumarin是 类胶原酶的肽酶的底物。N-(2,4-Dinitrophenyl)-proleu-gly-leu-trp-ala-D-arg 氨基酸化合物是脊椎动物 胶原酶的底物。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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IF：
7.6660
Publish_to：
Cells
PMID：
36496983
Quercetin attenuates DEHP-induced pyroptosis and programmed necrosis in chicken duodenum through regulation of the TLR4/MyD88/NF-κB pathway
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Author：
Ruirui Xie, Tong Xu, Yilin Yin, Meichen Liu, Chenxi Huang, Wenwen Zhang, Shu Li
IF：
7.6000
Publish_to：
ENVIRONMENTAL POLLUTION
PMID：
40057166
Injectable thermosensitive hydrogel to enhance the photothermal ablation and systemic immunotherapy of breast tumors
点击查看 >>
Author：
Tao Qin, Ruipeng Li, Huiqin Jin, Yunxia Wang, Liheng Feng
IF：
7.5900
Publish_to：
Biomaterials Science
PMID：
36053224
A tailored and red-emissive type I photosensitizer to potentiate photodynamic immunotherapy
点击查看 >>
Author：
Sirong Zhou, Ruipeng Li, Ying Li, Yunxia Wang, Liheng Feng
IF：
7.5710
Publish_to：
Journal of Materials Chemistry B
PMID：
36093913
Melatonin Synergizes With Mesenchymal Stromal Cells Attenuates Chronic Allograft Vasculopathy
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Author：
Qin Ya-fei, Kong De-jun, Qin Hong, Zhu Yang-lin, Li Guang-ming, Sun Cheng-lu, Zhao Yi-ming, Wang Hong-da, Hao Jing-peng, Wang Hao
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
33995416
sFgl2 gene-modified MSCs regulate the differentiation of CD4+ T cells in the treatment of autoimmune hepatitis
点击查看 >>
Author：
Ji Wenbin, Wang Weiwei, Li Peiyuan, Liu Yanhong, Zhang Baotong, Qi Feng
IF：
7.5000
Publish_to：
Stem Cell Research & Therapy
PMID：
37924141
LPCAT3 is transcriptionally regulated by YAP/ZEB/EP300 and collaborates with ACSL4 and YAP to determine ferroptosis sensitivity
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Author：
Mr. Jiangtao Cui, Dr. Yikun Wang, Ms. Xiaoting Tian, Ms. Yayou Miao, Prof. Lifang Ma, Ms. Congcong Zhang, Dr. Xin Xu, Dr. Jiayi Wang, Prof. Wentao Fang, Prof. Xiao Zhang
IF：
7.4680
Publish_to：
ANTIOXIDANTS & REDOX SIGNALING
PMID：
37166352
PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis
点击查看 >>
Author：
Youliang Zhao, Changfu Hao, Meng Li, Yaqian Qu, Yonghua Guo, Xuedan Deng, Huifang Si, Wu Yao
IF：
7.4190
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
35247717
Exosomes from Adipose-Derived Stem Cells Alleviate Dexamethasone-Induced Bone Loss by Regulating the Nrf2/HO-1 Axis
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Author：
Xue-wei Yao, Zhi-yi Liu, Neng-feng Ma, Wen-kai Jiang, Zhi Zhou, Bing Chen, Wen-gang Guan, Jun-jie Yan, Min Yang
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
36778207
Identification of potential ferroptosis-associated biomarkers in rheumatoid arthritis
点击查看 >>
Author：
Xu He, Juqi Zhang, Mingli Gong, Yanlun Gu, Bingqi Dong, Xiaocong Pang, Chenglong Zhang, Yimin Cui
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
37492576
EZH2 inhibits senescence-associated inflammation and attenuates intervertebral disc degeneration by regulating the cGAS/STING pathway via H3K27me3
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Author：
Jianrui Zheng, Zetao Ma, Pei Liu, Jiewen Wei, Shaoxiong Min, Ying Shan, Jianlin Zhang, Ye Li, Lixiang Xue, Zhen Tan, Deli Wang
IF：
7.2000
Publish_to：
OSTEOARTHRITIS AND CARTILAGE
PMID：
39938633
COPS6 promotes tumor progression and reduces CD8+ T cell infiltration by repressing IL-6 production to facilitate tumor immune evasion in breast cancer
点击查看 >>
Author：
Du Wen-qi, Zhu Zhi-man, Jiang Xin, Kang Meng-jie, Pei Dong-sheng
IF：
7.1690
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
37095198
Impaired AT2 to AT1 cell transition in PM2.5-induced mouse model of chronic obstructive pulmonary disease
点击查看 >>
Author：
Yu Hongjiao, Lin Yingnan, Zhong Yue, Guo Xiaolan, Lin Yuyin, Yang Siqi, Liu Jinglin, Xie Xinran, Sun Yaowei, Wang Dong, Li Bing, Ran Pixin, Dai Jianwei
IF：
7.1620
Publish_to：
RESPIRATORY RESEARCH
PMID：
35337337
YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription
点击查看 >>
Author：
Xue Xiangfei, Tian Xiaoting, Zhang Congcong, Miao Yayou, Wang Yikun, Peng Yingxiu, Qiu Shiyu, Wang Hong, Cui Jiangtao, Cao Leiqun, Sun Fenyong, Qiao Yongxia, Zhang Xiao
IF：
7.1090
Publish_to：
Cell Death Discovery
PMID：
35149670
Mechanical force regulates the paracrine functions of ADSCs to assist skin expansion in rats
点击查看 >>
Author：
Xue Zhixin, Hu Delin, Tang Haojing, Xue Mingheng, Zhu Yufan, Li Ye, Liao Yunjun
IF：
7.1000
Publish_to：
Stem Cell Research & Therapy
PMID：
39135129
A chlorogenic acid functional strategy of anti-inflammation, anti-coagulation and promoted endothelial proliferation for bioprosthetic artificial heart valves
点击查看 >>
Author：
Xiaotong Chen, Tao Yu, Qunshou Kong, Hong Xu, Zhiyu Zhao, Gaocan Li, Haojun Fan, Yunbing Wang
IF：
7.0000
Publish_to：
Journal of Materials Chemistry B
PMID：
36883900
Interleukin-7-loaded oncolytic adenovirus improves CAR-T cell therapy for glioblastoma
点击查看 >>
Author：
Huang Jianhan, Zheng Meijun, Zhang Zongliang, Tang Xin, Chen Yaxing, Peng Aijun, Peng Xingchen, Tong Aiping, Zhou Liangxue
IF：
6.9680
Publish_to：
CANCER IMMUNOLOGY IMMUNOTHERAPY
PMID：
33543339
miR-200a-3p-enriched MSC-derived extracellular vesicles reverse erectile function in diabetic rats by targeting Keap1
点击查看 >>
Author：
Jing Zhang, Danfeng Zhao, Zhenjie Zang, Zheng Ruan, Qiang Fu, Keqin Zhang
IF：
6.9000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38959607
Dynamics of the inhibitory immune checkpoint TIM-3 in mouse pulmonary phagocytes after silica exposure
点击查看 >>
Author：
Youliang Zhao, Yaqian Qu, Meixiu Duan, Changfu Hao, Wu Yao
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
37285680
Isolation, identification and osteogenic capability analysis of mesenchymal stem cells derived from different layers of human maxillary sinus membrane
点击查看 >>
Author：
Huixin Lv, Jing Xu, Yihan Wang, Xiuyu Liu, Sheng Chen, Jingxia Chen, Jingjie Zhai, Yanmin Zhou
IF：
6.7000
Publish_to：
JOURNAL OF CLINICAL PERIODONTOLOGY
PMID：
38379293
Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma
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Author：
Wang Yikun, Qiu Shiyu, Wang Hong, Cui Jiangtao, Tian Xiaoting, Miao Yayou, Zhang Congcong, Cao Leiqun, Ma Lifang, Xu Xin, Qiao Yongxia, Zhang Xiao
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
34765600
Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota
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Author：
He Ke-Jie, Dong Jia-Hui, Ouyang Xiao-Mei, Huo Ya-Ni, Cheng Xiao-Shen, Lin Ying, Li Yue, Gong Guoyu, Liu Jingjing, Ren Jian-Lin, Guleng Bayasi
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
36034889
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models
点击查看 >>
Author：
Zhengyun Chen, Chunyan Wang, Cuicui Lin, Lifeng Zhang, Huimei Zheng, Yong Zhou, Xiaoyong Li, Chen Li, Xinmei Zhang, Xiaohang Yang, Minxin Guan, Yongmei Xi
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
34552688
Plant-derived leaf vein scaffolds for the sustainable production of dog cell-cultured meat
点击查看 >>
Author：
Huina Luo, Huimin Ruan, Cailing Ye, Wenkang Jiang, Xin Wang, Shengfeng Chen, Zhisheng Chen, Dongsheng Li
IF：
6.5000
Publish_to：
Food Chemistry-X
PMID：
39100247
Monolith/Hydrogel composites as triamcinolone acetonide carriers for curing corneal neovascularization in mice by inhibiting the fibrinolytic system
点击查看 >>
Author：
Cixin Huang, Xia Qi, Huilin Chen, Chao Wei, Xiaolin Qi, Hongwei Wang, Hua Gao
IF：
6.4190
Publish_to：
DRUG DELIVERY
PMID：
34962228
Cancer-associated fibroblast exosome LINC00355 promotes epithelial-mesenchymal transition and chemoresistance in colorectal cancer through the miR-34b-5p/CRKL axis
点击查看 >>
Author：
Hu Jun-Hong, Tang Hong-Na, Wang Yu-Hang
IF：
6.4000
Publish_to：
CANCER GENE THERAPY
PMID：
38052858
A biomimetic hierarchical small intestinal submucosa–chitosan sponge/chitosan hydrogel scaffold with a micro/nano structure for dural repair
点击查看 >>
Author：
Jingxi Wang, Kun Li, Junwei Xu, Meili Liu, Ping Li, Xiaoming Li, Yubo Fan
IF：
6.3310
Publish_to：
Journal of Materials Chemistry B
PMID：
34586141
Ambient ultraviolet B radiation induced valve behavioral acclimation of Pacific oyster which resulted from the different response strategies of smooth and striated adductor muscles
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Author：
Hongce Song, Lei Wei, Mingyu Zhong, Xi Chen, Chaoyi Xie, Xiao Chen, Xiaona Wang, Baoyu Huang, Yaqiong Liu, Meiwei Zhang, Yitao Qi, Xiaotong Wang
IF：
6.2910
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
34863076
MicroRNA-381 Regulates Proliferation and Differentiation of Caprine Skeletal Muscle Satellite Cells by Targeting PTEN and JAG2
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Author：
Jiyuan Shen, Jiqing Wang, Huimin Zhen, Yan Liu, Lu Li, Yuzhu Luo, Jiang Hu, Xiu Liu, Shaobin Li, Zhiyun Hao, Mingna Li, Zhidong Zhao
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36362373
NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment
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Author：
Liangzheng Chang, Lei Xu, Yuying Tian, Zherui Liu, Meiru Song, Shuang Li, Xinfeng Zhang, Yue Chen, Qiuyao Hao, Yinying Lu, Yunhuan Zhen
IF：
6.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
38278335
Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p
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Author：
Yin Zhuang, Sheng Song, Dan Xiao, Xueguang Liu, Xiaofei Han, Shihao Du, Yuan Li, Yanming He, Shujun Zhang
IF：
6.1130
Publish_to：
Frontiers in Molecular Biosciences
PMID：
35111808
Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency
点击查看 >>
Author：
Ling-Zhen Liu, Long Liu, Zhi-Hong Shi, Xian-Ling Bian, Zi-Ru Si, Qi-Quan Wang, Yang Xiang, Yun Zhang
IF：
6.1070
Publish_to：
iScience
PMID：
37128610
Sweet Taste Receptor T1R3 Expressed in Leydig Cells Is Closely Related to Homeostasis of the Steroid Hormone Metabolism Profile
点击查看 >>
Author：
Weiyong Wang, Qi Mu, Xianzhou Feng, Wenjiao Liu, Houqiang Xu, Xiang Chen, Fangxiong Shi, Ting Gong
IF：
6.1000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
37186581
Galectin-9 Mediates the Therapeutic Effect of Mesenchymal Stem Cells on Experimental Endotoxemia
点击查看 >>
Author：
Zhao Yiming, Yu Dingding, Wang Hongda, Jin Wang, Li Xiang, Hu Yonghao, Qin Yafei, Kong Dejun, Li Guangming, Ellen Acheampong, Wang Hao
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
35252164
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats
点击查看 >>
Author：
Hu Li, Shuang You, Xia Yang, Shuaibin Liu, Lina Hu
IF：
6.0000
Publish_to：
Biomaterials Advances
PMID：
35599098
Mussel-inspired functionalization of electrospun scaffolds with polydopamine-assisted immobilization of mesenchymal stem cells-derived small extracellular vesicles for enhanced bone regeneration
点击查看 >>
Author：
Xin Xing, Shuang Han, Yifeng Ni, Gu Cheng, Yuet Cheng, Xiaoqi Ni, Yunfan Deng, Zhi Li, Zubing Li
IF：
5.8750
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
34592398
α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback
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Author：
Hu Ying-Hao, Han Jun, Wang Lin, Shi Chao, Li Yan, Olatunji Opeyemi Joshua, Wang Xiu, Zuo Jian
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34305602
Apical papilla stem cell-derived exosomes regulate lipid metabolism and alleviate inflammation in the MCD-induced mouse NASH model
点击查看 >>
Author：
Yi-Fei Nie, Jia-Ming Shang, Duan-Qin Liu, Wen-Qing Meng, Hui-Ping Ren, Chuan-Hua Li, Zhi-Feng Wang, Jing Lan
IF：
5.8000
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
38395263
Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia
点击查看 >>
Author：
Tong Xin, Li Danni, Liu Na, Huang Wanjie, Zhao Xinyi, Zhang Dan, Xue Xindong, Fu Jianhua
IF：
5.7000
Publish_to：
MOLECULAR MEDICINE
PMID：
37226090
Diabetic and nondiabetic BMSC–derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis
点击查看 >>
Author：
Zechuan Li, Bing Zhang, Jiaming Shang, Yanan Wang, Linglu Jia, Xiao She, Xin Xu, Dongjiao Zhang, Jing Guo, Fan Zhang
IF：
5.6000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37976598
Mammary Fibrosis Tendency and Mitochondrial Adaptability in Dairy Cows with Mastitis
点击查看 >>
Author：
Xingchi Kan, Guiqiu Hu, Yiyao Liu, Ping Xu, Yaping Huang, Xiangyu Cai, Wenjin Guo, Shoupeng Fu, Juxiong Liu
IF：
5.5810
Publish_to：
Metabolites
PMID：
36355118
Differences in chemotaxis of human mesenchymal stem cells and cervical cancer cells
点击查看 >>
Author：
Song Yizuo, Li Ruyi, Ye Miaomiao, Pan Chunyu, Zheng Lihong, Wang Zhi-wei, Zhu Xueqiong
IF：
5.5610
Publish_to：
APOPTOSIS
PMID：
35849265
Neuroprotective and antioxidant activities of different polarity parts of the extracts of the Ginkgo biloba leaf and Zingiber officinale rhizome from Yongzhou
点击查看 >>
Author：
Huang Zuoying, Yuan Tingting, Chen Jiayi, Jiang Mihan, Yan Rongling, Yang Wencai, Wang Liqian, Liao Yang, Huang Guowen
IF：
5.5450
Publish_to：
Frontiers in Chemistry
PMID：
36157036
Pirfenidone attenuates synovial fibrosis and postpones the progression of osteoarthritis by anti-fibrotic and anti-inflammatory properties in vivo and in vitro
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Author：
Wei Qilu, Kong Ning, Liu Xiaohui, Tian Run, Jiao Ming, Li Yiyang, Guan Huanshuai, Wang Kunzheng, Yang Pei
IF：
5.5310
Publish_to：
Journal of Translational Medicine
PMID：
33874948
3D pancreatic ductal adenocarcinoma desmoplastic model: Glycolysis facilitating stemness via ITGAV-PI3K-AKT-YAP1
点击查看 >>
Author：
Xiaoqi Guan, Di Wu, Hongyu Zhu, Biwen Zhu, Zhen Wang, Haowei Xing, Xue Zhang, Jiashuai Yan, Yibing Guo, Yuhua Lu
IF：
5.5000
Publish_to：
Biomaterials Advances
PMID：
39889369
Protective effect of the total flavonoids from Clinopodium chinense against LPS-induced mice endometritis by inhibiting NLRP3 inflammasome-mediated pyroptosis
点击查看 >>
Author：
Lili Li, Jiajia Qi, Hong Tao, Lele Wang, Lu Wang, Ning Wang, Qi Huang
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
37054825
Hyaluronic Acid-Grafted Bioprosthetic Heart Valves Achieved by Copolymerization Exhibited Improved Anticalcification and Antithrombogenicity
点击查看 >>
Author：
Xueyu Huang, Cheng Zheng, Kailei Ding, Meiling Li, Shumang Zhang, Binggang Wu, Qingrong Wei, Yang Lei, Yunbing Wang
IF：
5.3950
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
35839344
Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold
点击查看 >>
Author：
Bing-Yu Zhang, Pu Xu, Qing Luo, Guan-Bin Song
IF：
5.3260
Publish_to：
World Journal of Stem Cells
PMID：
33584983
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways
点击查看 >>
Author：
Chen Cheng, Shuai Tang, Shuyue Cui, Tong Yang, Lan Li, Mingrui Zhai, Fulan Wei, Gang Ding
IF：
5.3000
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
38333908
The upregulation of circFoxp1 influences keloid by promoting cell proliferation
点击查看 >>
Author：
Jing Zhang, Qianyi Bao, Nan Song, Chunming Li, Jing Ma
IF：
5.2000
Publish_to：
Aging-US
PMID：
37993257
An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery
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Author：
Yu Wang, Zhi-jian Lin, Jing Huang, Meng-zhen Chu, Xue-li Ding, Wen-jing Li, Qiu-yue Mao, Bing Zhang
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
35688256
Circ_0057452 sponges miR-7-5p to promote keloid progression through upregulating GAB1
点击查看 >>
Author：
Mengying Zhu, Yonglin Li, Linbo Liu, Xiaomei Zhai
IF：
5.1730
Publish_to：
CELL CYCLE
PMID：
35876480
The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity
点击查看 >>
Author：
Yi Chu, Sisi Gui, Yazhen Zheng, Jingwu Zhao, Yaxiang Zhao, Yingying Li, Xiaodong Chen
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38402928
A 1.1 Mb duplication CNV on chromosome 17 contributes to skeletal muscle development in Boer goats
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Author：
Ying Yuan, Wei-Yi Zhang, Bai-Gao Yang, Dong-Ke Zhou, Lu Xu, Yong-Meng He, Hao-Yuan Zhang, Cheng-Li Liu, Yue-Hui Ma, Ming-Xing Chu, Wen-Guang Zhang, Hui-Jiang Gao, Lin Jiang, Fu-Ping Zhao, Lu-Pei Zhang, Ri-Su Na, Baatarchogt Oyungerel, Yan-Guo Han, Yan Zen
IF：
4.9000
Publish_to：
ZOOLOGICAL RESEARCH
PMID：
36785897
PROTAC based STING degrader attenuates acute colitis by inhibiting macrophage M1 polarization and intestinal epithelial cells pyroptosis mediated by STING-NLRP3 axis
点击查看 >>
Author：
Shuai Xu, Yifeng Peng, Kai Yang, Sheng Liu, Zhanke He, Junli Huang, Ruipei Xiao, Jin Liu, Ziyan Yan, Zhiying Lian, Huayang Pan, Jianjun Chen, Jiaolong Shi, Xingxing Yao, Haijun Deng
IF：
4.8000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
39223062
BMP-2/TGF-β1 gene insertion into ligament-derived stem cells sheet promotes tendon–bone healing in a mouse
点击查看 >>
Author：
Bing Wei, Zhuang Li, Yucheng Lin, Xinyue Hu, Li Xu, Shanzheng Wang, Mingliang Ji, Jun Lu
IF：
4.7000
Publish_to：
Biotechnology Journal
PMID：
36683552
N-methyl-D-aspartate Receptor Subunits 2A and 2B Mediate Connexins and Pannexins in the Trigeminal Ganglion Involved in Orofacial Inflammatory Allodynia during Temporomandibular Joint Inflammation
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Author：
Li Yue-Ling, Zhang Yan-Yan, Song Qin-Xuan, Liu Fei, Liu Ya-Jing, Li Yi-Ke, Zhou Cheng, Shen Jie-Fei
IF：
4.6000
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
38976127
Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells
点击查看 >>
Author：
Li Mengyue, Wang Qiang, Han Qi, Wu Jiameng, Zhu Hongfan, Fang Yixuan, Bi Xiuting, Chen Yue, Yao Chao, Wang Xiaoying
IF：
4.5660
Publish_to：
Frontiers in Physiology
PMID：
34512380
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway
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Author：
Guoqiang Yang, Jiraporn Kantapan, Maryam Mazhar, Qiongdan Hu, Xue Bai, Yuanxia Zou, Honglian Wang, Sijin Yang, Li Wang, Nathupakorn Dechsupa
IF：
4.5000
Publish_to：
Journal of Inflammation Research
PMID：
38504697
Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice
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Author：
Zhi Li, Jianghua Wang, Chong Chen, Qi He, Xiaoying Xu, Zejiao Da, Bo Wang, Meng Wang, Xiaotong Gao, Guochao Zhang, Qi Gao, Xiaoli Si, Yanping Luo, Xingming Ma
IF：
4.4930
Publish_to：
Journal of Immunology Research
PMID：
35935577
Co-immunizing with HMGB1 enhances anti-tumor immunity of B7H3 vaccine in renal carcinoma
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Author：
Huanyou Sun, Juan Li, Wenwen Hu, Yinan Yan, Zengli Guo, Zichun Zhang, Yuxin Chen, Xuefan Yao, Ling Teng, Xinyuan Wang, Liantao Li, Dafei Chai, Junnian Zheng, Gang Wang
IF：
4.4070
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
34560414
MicroRNA-129-1-3p attenuates autophagy-dependent cell death by targeting MCU in granulosa cells of laying hens under H2O2-induced oxidative stress
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Author：
Mingkun Zhu, Ming Yan, Jianfei Chen, Huaiyu Li, Yeshun Zhang
IF：
4.4000
Publish_to：
POULTRY SCIENCE
PMID：
37595500
Endoplasmic reticulum-mitochondria coupling attenuates vanadium-induced apoptosis via IP3R in duck renal tubular epithelial cells
点击查看 >>
Author：
Junjun Peng, Chengcheng Peng, Li Wang, Huabin Cao, Chenghong Xing, Guyue Li, Guoliang Hu, Fan Yang
IF：
4.3360
Publish_to：
JOURNAL OF INORGANIC BIOCHEMISTRY
PMID：
35421768
Noncanonical Wnt5a Signaling Suppresses Hippo/TAZ-Mediated Osteogenesis Partly Through the Canonical Wnt Pathway in SCAPs
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Author：
Yajing Fu, Dan Ma, Fengyan Fan, Tongke Sun, Ruiqi Han, Yanran Yang, Jun Zhang
IF：
4.3190
Publish_to：
Drug Design Development and Therapy
PMID：
35237028
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system
点击查看 >>
Author：
Wei Fu, Chao Dai, Zifeng Ma, Qiao Li, Daoliang Lan, Changpo Sun, Xin Wu, Jian Li, Shujin Wang
IF：
4.3000
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
38272172
Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs
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Author：
Xiaodong Jing, Yulin Gao, Songlin Xiao, Qin Qin, X
IF：
4.2590
Publish_to：
Scientific Reports 6, Article number: 30468 (2016)
PMID：
27456656
A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression
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Author：
Hongxia Zhao, Lingge Huang, Jian Liu, Min Feng, Yeqian Liu, Hong Li, Shan Gong, Chunming Chen, Shuiqing Zeng, Weiqiong Ren
IF：
4.2000
Publish_to：
Frontiers in Cellular Neuroscience
PMID：
40230380
p38MAPK silencing attenuates scar proliferation after cleft palate repair surgery in rats via MRTF-A/SRF pathway
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Author：
Qian Ding, Gong-jun Wang, Ling-fa Xue, Jin Yue, Yao-xiang Xu, Zhen-zhen Fu, Wen-lin Xiao
IF：
4.1450
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
35690133
Expression of the umami taste receptor T1R1/T1R3 in porcine testis of: function in regulating testosterone synthesis and autophagy in Leydig cells
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Author：
Ting Gong, Qi Mu, Yongjian Xu, Weiyong Wang, Lijie Meng, Xianzhou Feng, Wenjiao Liu, Zheng Ao, Yiyu Zhang, Xiang Chen, Houqiang Xu
IF：
4.1000
Publish_to：
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
PMID：
38035949
Transcriptomic Analysis of MSTN Knockout in the Early Differentiation of Chicken Fetal Myoblasts
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Author：
Ke Xu, Hao Zhou, Chengxiao Han, Zhong Xu, Jinmei Ding, Jianshen Zhu, Chao Qin, Huaixi Luo, Kangchun Chen, Shengyao Jiang, Jiajia Liu, Wenqi Zhu, He Meng
IF：
4.0960
Publish_to：
Genes
PMID：
35052399
Botulinum toxin A promotes the transdifferentiation of primary keloid myofibroblasts into adipocyte-like cells
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Author：
Xing Dai, Tie-Chi Lei
IF：
4.0840
Publish_to：
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
PMID：
34571584
Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice
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Author：
Huang Ping, Ma Huihui, Cao Yun, Zhan Tingzheng, Zhang Tingting, Wang Xinyi, Zhang Yanan, Xu Jing, Xia Chaoming
IF：
4.0470
Publish_to：
Parasites & Vectors
PMID：
36474240
Ligusticum chuanxiong promotes the angiogenesis of preovulatory follicles (F1–F3) in late-phase laying hens
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Author：
Hao Chen, Xin Chen, Zhenlei Ping, Lixue Fang, Xiaowen Jiang, Ming Ge, Jun Ma, Wenhui Yu
IF：
4.0140
Publish_to：
POULTRY SCIENCE
PMID：
36621100
VEGFA-modified DPSCs combined with LC-YE-PLGA NGCs promote facial nerve injury repair in rats
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Author：
Wanqiu Xu, Xiaohang Xu, Lihong Yao, Bing Xue, Hualei Xi, Xiaofang Cao, Guiyan Piao, Song Lin, Xiumei Wang
IF：
4.0000
Publish_to：
Heliyon
PMID：
37095964
Hypermethylation of the GRHL2 promoter region is associated with ovarian endometriosis
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Author：
Yali Hao, Yan Li, Jianlei Wu, Na Hao, Yuzhen Qin, Haibo zhang, Wei Zhao, Shan Kang
IF：
3.9230
Publish_to：
REPRODUCTION
PMID：
35356893
The Effects of Zinc Oxide Nanoparticles on Antioxidation, Inflammation, Tight Junction Integrity, and Apoptosis in Heat-Stressed Bovine Intestinal Epithelial Cells In Vitro
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Author：
Li Yuanxiao, Pan Mengying, Meng Sudan, Xu Wenhao, Wang Shuai, Dou Mengying, Zhang Cai
IF：
3.9000
Publish_to：
BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
37648935
Low androgen status inhibits erectile function by increasing pyroptosis in rat corpus cavernosum
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Author：
Zhi-bin Chen, Ge Li, Haocheng Lin, Jun Jiang, Rui Jiang
IF：
3.8420
Publish_to：
Andrology
PMID：
33657666
LIPUS can promote osteogenesis of hPDLCs and inhibit the periodontal inflammatory response via TLR5
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Author：
Ping Li, Zhipeng Zhang, Jingjing Liu, Hui Xue
IF：
3.8000
Publish_to：
ORAL DISEASES
PMID：
37983889
Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells
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Author：
Renye Que, Mengxing Cao, Yancheng Dai, Yi Zhou, Yirong Chen, Liubing Lin
IF：
3.7300
Publish_to：
Biochemistry and Cell Biology
PMID：
35785548
Tea polyphenols protect bovine intestinal epithelial cells from the adverse effects of heat-stress in vitro
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Author：
Sudan Meng, Yongsheng An, Yuexin Wang, Shuai Wang, Hongwei Wang, Qi Shao, Mengying Dou, Lei He, Cai Zhang
IF：
3.7000
Publish_to：
ANIMAL BIOTECHNOLOGY
PMID：
37647094
GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance
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Author：
Hongshuai Li, Yuan Wang, Mengchu Ma, Lihong Hu, Xinxin Zhang, Lingbiao Xin, Wei Zhang, Xiaoming Sun, Yuanyuan Ren, Xinting Wang, Jie Yang
IF：
3.6850
Publish_to：
IMMUNOLOGY LETTERS
PMID：
33838181
Anti-atherosclerotic effects of genistein in preventing ox-low-density lipoprotein-induced smooth muscle-derived foam cell formation via inhibiting SRC expression and L-Ca channel currents
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Author：
Wei Zhang, Liming Zhang, Xiaosi Zhang
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
35845495
CA1 Modulates the Osteogenic Differentiation of Dental Follicle Stem Cells by Activating the BMP Signaling Pathway In Vitro
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Author：
Zhao Jin-ze, Ge Ying-Ying, Xue Ling-fa, Xu Yao-xiang, Yue Jin, Li Cong, Xiao Wen-lin
IF：
3.6000
Publish_to：
Tissue Engineering and Regenerative Medicine
PMID：
38652220
LncRNA FPASL suppresses fibroblast proliferation through its DNA methylation via DNMT3b in hypertrophic scar: DNMT3b-mediated lncRNA FPASL in fibroblast proliferation
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Author：
Kai Wu, Fang Ma, Jiangyong Shen, Hui Zhang, Yu Wan, Xi He, Anning Yang, Jiantuan Xiong, Yun jiao, Zhigang Bai, Shengchao Ma, Yideng Jiang, Huiping Zhang, Yinju Hao
IF：
3.5110
Publish_to：
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
PMID：
36514215
Effect of dermatopontin on osteogenic differentiation of periodontal ligament stem cells
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Author：
Xuechun Zhao, Zhigang Xie, Nanquan Rao, Shu Zhang, Yunpeng Zhang
IF：
3.5000
Publish_to：
GENE
PMID：
36632910
Hybrid Broussonetia papyrifera Fermented Feed Can Play a Role Through Flavonoid Extracts to Increase Milk Production and Milk Fatty Acid Synthesis in Dairy Goats
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Author：
Mengjie Zhao, Dongliang Lv, Jingcao Hu, Yonglong He, Zhi Wang, Xinyu Liu, Benkang Ran, Jianhong Hu
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
35359682
A study of the role of multiple layer-by-layer assembled bionic extracellular matrix in promoting wound healing via activation of the Wnt signaling pathway
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Author：
Zehui Wang, Kun Cao, Di Yan, Yangjing Ge, Ruiyuan Li, Yanwen Liu, Ting Ma, Xiaojuan Sun
IF：
3.4000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
PMID：
36633398
Photobiomodulation therapy enhances neural differentiation of dental pulp stem cells via ERK1/2 signaling pathway
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Author：
Xinran Zhang, Haotian Li, Lu Tang, Biao Zhu, Wenwen Yang, Miao Li, Ying Zhao
IF：
3.3000
Publish_to：
PHOTOCHEMISTRY AND PHOTOBIOLOGY
PMID：
37815161
Effects of compound probiotics and aflatoxin-degradation enzyme on alleviating aflatoxin-induced cytotoxicity in chicken embryo primary intestinal epithelium, liver and kidney cells
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Author：
Guo Hong-Wei, Chang Juan, Wang Ping, Yin Qing-Qiang, Liu Chao-Qi, Xu Xiao-Xiang, Dang Xiao-Wei, Hu Xiao-Fei, Wang Quan-Liang
IF：
3.2980
Publish_to：
AMB Express
PMID：
33646441
Effect of cell culture models on the evaluation of anticancer activity and mechanism analysis of the potential bioactive compound, iturin A, produced by Bacillus subtilis
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Author：
H Zhao, X Zhao, S Lei, Y Zhang, D Shao, C Jiang
IF：
3.2890
Publish_to：
Food & function
PMID：
30778489
In vitro and in vivo antitumor activity of a novel porphyrin-based photosensitizer for photodynamic therapy
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Author：
Jing-Jing Chen Ge Hong Li-Jing Gao Tian-Jun Liu
IF：
3.2820
Publish_to：
Journal of Cancer Research and Clinical Oncology
PMID：
25609073
Characteristics and Expression of circ_003628 and Its Promoted Effect on Proliferation and Differentiation of Skeletal Muscle Satellite Cells in Goats
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Author：
Huimin Zhen, Jiyuan Shen, Jiqing Wang, Yuzhu Luo, Jiang Hu, Xiu Liu, Shaobin Li, Zhiyun Hao, Mingna Li, Bingang Shi, Yuanhua Gu
IF：
3.2310
Publish_to：
Animals
PMID：
36230263
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro
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Author：
Yan Linghu, Chao-Nan Deng, Li He, Qi Wu, Lin Xu, Yan-Ni Yu
IF：
3.2000
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
PMID：
37638639
Transcriptomic analysis and biological evaluation reveals that LMO3 regulates the osteogenic differentiation of human adipose derived stem cells via PI3K/Akt signaling pathway
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Author：
Kang Yue, Pei Wenye
IF：
3.1560
Publish_to：
JOURNAL OF MOLECULAR HISTOLOGY
PMID：
35165791
Kojic acid inhibits senescence of human corneal endothelial cells via NF- B and p21 signaling pathways
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Author：
XiWeiabDanLuoaYuYanabHaiyangYuabLiyaoSunabChaoWang
IF：
3.1520
Publish_to：
Experimental Eye Research
PMID：
30597146
Role of neutrophil myeloperoxidase in the development and progression of high-altitude pulmonary edema
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Author：
Huan Zhang, Xiaojun Wang, Jie Liu, Yu Zhang, Maojia Ka, Yi Ma, Jiaolong Xu, Wei Zhang
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
38382360
Buffalo bbu-miR-493-5p Promotes Myoblast Proliferation and Differentiation
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Author：
Liyin Zhang, Dandan Zhong, Chengxuan Yao, Qingyou Liu, Deshun Shi, Mingsheng Jiang, Jian Wang, Zhaocheng Xiong, Hui Li
IF：
3.0000
Publish_to：
Animals
PMID：
38396500
Total Glucosides of Paeony Regulate Immune Imbalance Mediated by Dermal Mesenchymal Stem Cells in Psoriasis Mice
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Author：
Lei Ming-jun, Bai Fan, Zhang Qing-yun, Yang Qing-qing, Tian Zan
IF：
2.9000
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
37222920
On-chip construction of a fully structured scaffold-free vascularized renal tubule
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Author：
Zhu Yuntian, Shi Zhengdi, Ding Weiping, Li Chengpan
IF：
2.8000
Publish_to：
BIOMEDICAL MICRODEVICES
PMID：
36826720
Biological activity of a vascular endothelial cell‑hydroxyapatite orbital implant complex: An experimental study
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Author：
Weiqi Wu, Hao Luo, Dan Wu, Menglin Shi, Jinhai Yu, Hongfei Liao
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
35222704
Characterization and differentiation potential of mesenchymal stem cells isolated from multiple canine adipose tissue sources
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Author：
Rashid Usman, Yousaf Arfan, Yaqoob Muhammad, Saba Evelyn, Moaeen-ud-Din Muhammad, Waseem Shahid, Becker Sandra K., Sponder Gerhard, Aschenbach Jörg R., Sandhu Mansur Abdullah
IF：
2.7410
Publish_to：
BMC Veterinary Research
PMID：
34922529
Expression patterns and correlation analyses of muscle-specific genes in the process of sheep myoblast differentiation
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Author：
Wang Hejie, Dou Minmin, Li Jun, Cao Peng, Li Junling, Guo Tianyan, Zhao Dipeng, Khan Ajab, Li Yingliang, Li Baojun, Qin Jian, Du Rong
IF：
2.7230
Publish_to：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
PMID：
36178582
Antioxidant monoammonium glycyrrhizinate alleviates damage from oxidative stress in perinatal cows
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Author：
Cai Zhang, Chenxu Li, Qi Shao, Sudan Meng, Xueying Wang, Tao Kong, Yu Li
IF：
2.7180
Publish_to：
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
PMID：
35989475
Exploring the Role and Mechanism of Adipose Derived Mesenchymal Stem Cells on Reversal of Pigmentation Model Effects
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Author：
Dou Shuqian, Yang Yifei, Zhang Jiping, He Zeliang, Wu Zeyi, Zhao Yiman, Zhang Kai, Liu Yingqi, Li Yanhui, Miao Xiaoyan, Miao Guoying, Liu Mei
IF：
2.7080
Publish_to：
AESTHETIC PLASTIC SURGERY
PMID：
35441235
PNX14 but not PNX20 as a novel regulator of preadipocyte differentiation via activating Epac-ERK signaling pathway in Gallus gallus
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Author：
Tuoyuan Liu, Ming Yang, Yuping Wu, Guixian Bu, Xingfa Han, Xiaogang Du, Qiuxia Liang, Xiaohan Cao, Anqi Huang, Xianyin Zeng, Fengyan Meng
IF：
2.7000
Publish_to：
GENERAL AND COMPARATIVE ENDOCRINOLOGY
PMID：
36774983
Effects of mechanosensitive ion channel Piezo1 on proliferation and osteogenic differentiation of human dental follicle cells
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Author：
Yanyan Xing, Binbin Yang, Yun He, Bingqing Xie, Tianqi Zhao, Junliang Chen
IF：
2.6980
Publish_to：
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
PMID：
34687906
Primary culture of adult cortical neurons from reptile Gekko japonicus
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Author：
Bingqiang He, Chunshuai Sun, Hui Li, Ting Yang, Honghua Song, Yongjun Wang, Yingjie Wang
IF：
2.6100
Publish_to：
JOURNAL OF ANATOMY
PMID：
34047374
Transcriptome sequencing of facial adipose tissue reveals alterations in mRNAs of hemifacial microsomia
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Author：
Bingyang Liu, Wei Liu, Shanbaga Zhao, Lunkun Ma, Tianying Zang, Changjin Huang, Kaiyi Shu, Hengbin Gao, Xiaojun Tang
IF：
2.6000
Publish_to：
Frontiers in Pediatrics
PMID：
36861077
Polysaccharide from alfalfa activates RAW 264.7 macrophages through MAPK and NF- B signaling pathways
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Author：
Y Xie, L Wang, H Sun, Y Wang, Z Yang, G Zhang
IF：
2.5960
Publish_to：
International journal of Biological Macromolecules
PMID：
30590152
Synthesis and Characterization of Biodegradable Polyurethane for Hypopharyngeal Tissue Engineering
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Author：
Zhisen Shen,Dakai Lu,Qun Li,Zongyong Zhang,and Yab
IF：
2.5830
Publish_to：
BioMed Research International
PMID：
25839041
γδT Cells Induce the Inflammatory Response of Human Fibroblast-Like Synoviocytes Directly or by Stimulating B Cells to Activate IL-17/STAT3 Signaling Pathway
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Author：
He Fang, Yu Juan, Ma Sha, Zhao Weiqing, Zhang Mingxing, Wang Juan, Zhang Chunpan, Wu Jiangping, Zhu Lixuan
IF：
2.5000
Publish_to：
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
PMID：
38991517
Trehalose inhibits proliferation while activates apoptosis and autophagy in rat airway smooth muscle cells
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Author：
Bo Xiao, Haiming Huang, Liangxian Li, Lixia Hou, Dong Yao, Biwen Mo
IF：
2.4790
Publish_to：
ACTA HISTOCHEMICA
PMID：
34749031
Comparison of the differentiation abilities of bone marrow‑derived mesenchymal stem cells and adipose‑derived mesenchymal stem cells toward nucleus pulposus‑like cells in three‑dimensional culture
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Author：
Xuejun Dai, Yanyu Guan, Zhongzi Zhang, Ying Xiong, Chengwei Liu, Haifeng Li, Bailian Liu
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
34373704
Carboxymethyl chitin or chitosan for osteoinduction effect on the human periodontal ligament stem cells
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Author：
Chun FAN, Zhiyuan LI, Qiuxia JI, Hui SUN, Ye LIANG, Pishan YANG
IF：
2.4180
Publish_to：
DENTAL MATERIALS JOURNAL
PMID：
35249903
Cepharanthine Mitigates NIBV-induced Pyroptosis via the MDA5/NF-κB/NLRP3 Signaling Pathway
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Author：
Zhenni Liu, Ruoyun Tang, Mengbing Ding, Meiqin Wu, Ying Li, Cheng Huang, Qiurong Qi, Ping Liu, Xiaona Gao, Xiaoquan Guo
IF：
2.4000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
40273551
Circ-AFF2/miR-650/CNP axis promotes proliferation, inflammatory response, migration, and invasion of rheumatoid arthritis synovial fibroblasts
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Author：
Qu Wei, Jiang Ling, Hou Guanhua
IF：
2.3590
Publish_to：
Journal of Orthopaedic Surgery and Research
PMID：
33653372
Transcriptomics analysis of Daheng broilers reveals that PLIN2 regulates chicken preadipocyte proliferation, differentiation and apoptosis
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Author：
Li Jingjing, Yang Chaowu, Ren Peng, Lin Zhongzhen, Zhang Donghao, Jiang Xiaosong, Wang Li, Liu Yiping
IF：
2.3160
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
34716501
Effects of progesterone on the lipolysis of lipid droplets and prostaglandin E2 synthesis in murine cervical epithelial cells
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Author：
Hongyan Zhang, Feng Su, Libo Huang, Boyu Li, Xuejun Yuan, Mingjiu Luo, Lijiang Ge, Hongyan Zhang, Feng Su, Libo Huang, Boyu Li, Xuejun Yuan, Mingjiu Luo, Lijiang Ge
IF：
2.3110
Publish_to：
REPRODUCTION FERTILITY AND DEVELOPMENT
PMID：
33504425
Equine adipose tissue-derived extracellular vesicles enhance adipose mesenchymal stem cell survival ex vivo
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Author：
Dongsheng Li, Xin Wang, Junyong Yao, Shengfeng Chen
IF：
2.3000
Publish_to：
VETERINARY JOURNAL
PMID：
39978576
L-arginine reduces injury from heat stress to bovine intestinal epithelial cells by improving antioxidant and inflammatory response
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Author：
Mengying Dou, Yao Zhang, Qi Shao, Jiali Zhu, Wang Li, Xueying Wang, Cai Zhang, Yuanxiao Li
IF：
2.2710
Publish_to：
ANIMAL BIOTECHNOLOGY
PMID：
34870558
A long non-coding RNA lnc210 promotes adipogenic differentiation of buffalo intramuscular adipocytes
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Author：
Ruirui Zhu, Duo Guo, Ruirui Li, Ye Feng, Xintong Yang, Qixin Huang, Yuanyu Zheng, Deshun Shi, Jieping Huang
IF：
2.1410
Publish_to：
ANIMAL BIOTECHNOLOGY
PMID：
36001396
Mutation of FLNA attenuating the migration of abdominal muscles contributed to Melnick–Needles syndrome (MNS) in a family with recurrent miscarriage
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Author：
Xin Luo, Zailin Yang, Jing Zeng, Jing Chen, Ningxuan Chen, Xiaoyan Jiang, Qinlv Wei, Ping Yi, Jing Xu
IF：
2.0000
Publish_to：
Molecular Genetics & Genomic Medicine
PMID：
36734119
Melatonin protects sheep endometrial epithelial cells against lipopolysaccharide-induced inflammation in vitro
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Author：
Wenbo Ge, Hongwei Duan, Jianling Zeng, Xingxu Zhao, Jianyong Li, Junjie Hu
IF：
1.8580
Publish_to：
REPRODUCTION IN DOMESTIC ANIMALS
PMID：
36018566
Adipose-derived mesenchymal stem cells secrete extracellular vesicles: A potential cell-free therapy for canine renal ischaemia-reperfusion injury
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Author：
Haifeng Liu, Liyuan Huang, Fuhao Chen, Zhijun Zhong, Xiaoping Ma, Ziyao Zhou, Suizhong Cao, Liuhong Shen, Guangneng Peng
IF：
1.7000
Publish_to：
Veterinary Medicine and Science
PMID：
36913179
Low-Intensity Nanosecond Pulsed Electric Field Accelerates Osteogenic Transformation of Human Dermal Fibroblasts by Enhancing Cell Pluripotency
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Author：
Jingtian Lai, Zewei Wang, Haiying Zhou, Pengfei Li, Hui Lu, Tian Tu
IF：
1.6000
Publish_to：
Cellular Reprogramming
PMID：
38011697
Decellularized nerve extracellular matrix/chitosan crosslinked by genipin to prepare a moldable nerve repair material
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Author：
Zhang Fangsong, Zhang Naili, Xu Qing, Zhang Luping, Zhang Chunlei, Liu Hongfu, Yu Zhenhai, Zhou Shuai, Feng Guoying, Huang Fei
IF：
1.5220
Publish_to：
CELL AND TISSUE BANKING
PMID：
34115245
技术问答
（7）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
这个怎么配置啊，直接用1mg/ml的储备液吗?2023-05-05 17:32:08
您好，本品可以用TESCA溶液（G0150）配制，也可以用含钙镁的PBS、含钙镁的Hanks或不含血清的培养基配置，具体的使用浓度需要根据实验调整。
胶原酶1活力单位是多少？ U/mg?2023-03-30 18:54:19
您好，在 pH 7.4，37℃以及钙离子存在的条件下，以每5小时从胶原中释放的多肽相当于茚三酮显色1微摩尔亮氨酸量为一个活性单位。
I型胶原酶粉末怎么配成溶液使用?2023-03-24 14:30:10
您好，胶原酶Ⅰ可以用 TESCA buffer （50 mM TES，0.36 mM 氯化钙，pH7.4，37°C）配制成1-2 mg/ml，也可以用含钙镁的 PBS、含钙镁的 hanks 或不含血清的培养基配制。
使用胶原酶1溶液消化组织时，需要避光和37摄氏度培养箱吗?2023-03-22 21:40:57
您好，在消化组织时无需避光，可以在37℃下进行消化。
您好！这款试剂可以用来提脂肪原代细胞吗?2023-02-08 11:22:35
您好，可以的，胶原酶I也常用于上皮、肺和肾上腺组织细胞的分离。