Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells
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Author：
Liu Y; Ma G; Gao Z; Li J; Wang J; Zhu X; Ma R; Yan
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Nucleic Acids Res
HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing
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Author：
Yang Chao, Ma Zhenzhen, Wang Keshan, Dong Xingxiao, Huang Meiyu, Li Yaqiu, Zhu Xiagu, Li Ju, Cheng Zhihui, Bi Changhao, Zhang Xueli
Publish_to：
Nature Communications
Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells
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Author：
Zhao Na, Zhou Jian, Tao Tianfu, Wang Qi, Tang Jie, Li Dengluan, Gou Shixue, Guan Zhihong, Olajide Joshua Seun, Lin Jiejing, Wang Shuo, Li Xiaoping, Zhou Jiankui, Gao Zongliang, Wang Gang
Publish_to：
Nature Communications
Small molecule inhibits KCNQ channels with a non-blocking mechanism
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Author：
Li Junnan, Yang Zhenni, Zhang Shaoying, Ye Yangliang, He Jiangnan, Zhang Yan, Han Huayun, Kong Wan, Liu Jiangru, Min Yu, Shen Juwen, Mei Lianghe, Chen Zongsheng, Hou Panpan, Guo Jiangtao, Zhang Qiansen, Yang Huaiyu
Publish_to：
Nature Chemical Biology
Obtaining the best igRNAs for bystander-less correction of all ABE-reversible pathogenic SNVs using high-throughput screening
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Author：
Bo Li, Dongdong Zhao, Yaqiu Li, Yuanzhao Yang, Xiagu Zhu, Ju Li, Changhao Bi, Xueli Zhang
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MOLECULAR THERAPY
In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer
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Author：
Liu Lu, Lei Yuxi, Chen Wensheng, Zhou Qian, Zheng Zongyao, Zeng Guandi, Liu Wanting, Feng Pengju, Zhang Zhiyi, Yu Lei, Chen Liang
Publish_to：
Cell and Bioscience
Imperatorin alleviates cancer cachexia and prevents muscle wasting via directly inhibiting STAT3
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Author：
Chen L; Xu W; Yang Q; Zhang H; Wan L; Xin B; Zhang J; Guo C.
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Pharmacological Research
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability
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Author：
Feihu Zhao, Zhong Yao, Yaquan Li, Wenbo Zhao, Yanfei Sun, Xiaobing Yang, Zhimin Zhao, Bin Huang, Jian Wang, Xingang Li, Anjing Chen
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CANCER LETTERS
Bivalent activity of super-enhancer RNA LINC02454 controls 3D chromatin structure and regulates glioma sensitivity to temozolomide
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Author：
Shi Tengfei, Guo Dianhao, Zheng Yaoqiang, Wang Wenbin, Bi Jinfang, He Anshun, Fan Sibo, Su Guangsong, Zhao Xueyuan, Zhao Zhenhao, Song Yingjie, Sun Shupeng, Li Peng, Zhao Zhongfang, Shi Jiandang, Lu Wange, Zhang Lei
Publish_to：
Cell Death & Disease
RUVBL1 ubiquitination by DTL promotes RUVBL1/2-β-catenin-mediated transcriptional regulation of NHEJ pathway and enhances radiation resistance in breast cancer
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Author：
Tian Jie, Wen Mingxin, Gao Peng, Feng Maoxiao, Wei Guangwei
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Cell Death & Disease
RAB4B and Japanese encephalitis virus E protein interaction is essential for viral entry in early endosomes
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Author：
Chang Miao, Qin Zhao, Ya-Ting Zhang, Sai-Qi Luo, Xinfeng Han, Yiping Wen, Rui Wu, Qi-Gui Yan, Xiaobo Huang, Yiping Wang, Shan Zhao, Yi-Fei Lang, Yi Zheng, Fei Zhao, Senyan Du, San-Jie Cao
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation
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Author：
Lin Qimei, Cao Jiasong, Du Xiaoling, Yang Kuo, Yang Xu, Liang Zhixian, Shi Jiandang, Zhang Ju
Publish_to：
Cell Communication and Signaling
LINC00478-derived novel cytoplasmic lncRNA LacRNA stabilizes PHB2 and suppresses breast cancer metastasis via repressing MYC targets
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Author：
Guo Rong, Su Yonghui, Zhang Qi, Xiu Bingqiu, Huang Sheng, Chi Weiru, Zhang Liyi, Li Lun, Hou Jianjing, Wang Jia, Chen Jiajian, Chi Yayun, Xue Jingyan, Wu Jiong
Publish_to：
Journal of Translational Medicine
Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment
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Author：
He S, Chu X, Wu Y, Jiang J, Fang P, Chen Y, Liu Y, Qiu Z, Xiao Y, Li Z, Pan D, Zhang Q, Xie H, Xing S, Feng F, Liu W, Guo Q, Zhao L, Yang P, Sun H.
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy
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Author：
Ye Miaomiao, Liu Tingxian, Miao Liqing, Ji Huihui, Xu Zhihui, Wang Huihui, Zhang Jian’an, Zhu Xueqiong
Publish_to：
Stem Cell Research & Therapy
Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting Nlrp3 Expression
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Author：
Yue Wang, Bo Song, Jiebiao Chen, Jinping Cao, Xian Li, Chongde Sun
Publish_to：
Oxidative Medicine and Cellular Longevity
The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer
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Author：
Lin Qimei, Cao Jiasong, Du Xiaoling, Yang Kuo, Shen Yongmei, Wang Weishu, Klocker Helmut, Shi Jiandang, Zhang Ju
Publish_to：
Frontiers in Oncology
Identification of NECTIN1 as a novel restriction factor for flavivirus infection
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Author：
Shuhui Qi, Chao Sun, Jing Wang, Lijing Wo, Yongfeng Li, Chaonan Wang, Ying Zhang, Haiqiao Bian, Yongqi Guo, Ming Gao, Menghang Wang, Yandong Tang, Yuanmao Zhu, Fei Xue, Quanhai Pang, Zhigang Jiang, Xin Yin
DYRK2 downregulation in colorectal cancer leads to epithelial–mesenchymal transition induction and chemoresistance
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Author：
Wu Chunrong, Sun Guiyin, Wang Fan, Chen Jiangyan, Zhan Fangbiao, Lian Xiaojuan, Wang Jie, Weng Fanbin, Li Bo, Tang Weijun, Quan Jin, Xiang Debing
Publish_to：
Scientific Reports
HSP90AB1 is a host factor that promotes Porcine deltacoronavirus replication
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Author：
Yujia Zhao, Jianlin Yuan, Dai Xiao, Luwen Zhang, Cheng Li, Jingfei Hu, Rui Chen, Daili Song, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Xintian Wen, Sanjie Cao, Xiaobo Huang
Publish_to：
JOURNAL OF BIOLOGICAL CHEMISTRY
Hepatitis B Virus Core Protein Is Not Required for Covalently Closed Circular DNA Transcriptional Regulation
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Author：
Zhong Y. Wu C. Xu Z. Teng Y. Zhao L. Zhao K. Wang
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes-associated HLA-B39 allotypes
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Author：
A. W. Peshala Amarajeewa, Aslihan Özcan, Alveena Mukhtiar, Xu Ren, Qianyu Wang, Pemra Ozbek, Malgorzata A. Garstka, Onur Serçinoğlu
Publish_to：
EUROPEAN JOURNAL OF IMMUNOLOGY
HIF-1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cells
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Author：
CuiP;ZhangP;ZhangY;SunL;CuiG;GuoX;WangH;ZhangX;Shi
Inhibition of SARS-CoV-2 Replication by Self-Assembled siRNA Nanoparticles Targeting Multiple Highly Conserved Viral Sequences
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Author：
Jianan Sun, Siya Lu, Jizhen Xiao, Nuo Xu, Yingbin Li, Jinfeng Xu, Maohua Deng, Hanlu Xuanyuan, Yushi Zhang, Fangli Wu, Weibo Jin, Kuancheng Liu
Publish_to：
Viruses-Basel
PER3 plays anticancer roles in the oncogenesis and progression of breast cancer via regulating MEK/ERK signaling pathway
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Author：
Liu Yinfeng, Wu Zizheng, Li Yanli, Zhang Jing, Gao Yang, Yuan Guanli, Han Meng
Publish_to：
Journal of the Chinese Medical Association
miR-33a-5p enhances the sensitivity of lung adenocarcinoma cells to celastrol by regulating mTOR signaling
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Author：
Li YJ， Sun YX， Hao RM， Wu P， Zhang LJ， Ma X， Ma Y， Wang PY， Xie N， Xie SY， Chen W
Publish_to：
International Journal of Oncology
Long intergenic non-protein coding RNA 02570 promotes nasopharyngeal carcinoma progression by adsorbing microRNA miR-4649-3p thereby upregulating both sterol regulatory element binding protein 1, and fatty acid synthase
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Author：
Fei Liu, Jiazhang Wei, Yanrong Hao, Jiao Lan, Wei Li, Jingjin Weng, Min Li, Cheng Su, Bing Li, Mingzheng Mo, Fengzhu Tang, Yongli Wang, Yong Yang, Wei Jiao, Shenhong Qu
Publish_to：
Bioengineered
Micro RNA-175 Targets Claudin-1 to Inhibit Madin–Darby Canine Kidney Cell Adhesion
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Author：
Xiaoyun Li, Fangfang Ma, Siya Wang, Tian Tang, Liyuan Ma, Zilin Qiao, Zhongren Ma, Jiamin Wang, Zhenbin Liu
Vitamin D3 suppresses the cholesterol homeostasis pathway in patient-derived glioma cell lines
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Author：
Ran Yuan, Wei Zhang, Yong-Ping You, Gang Cui, Zhengliang Gao, Xiuxing Wang, Jian Chen
Publish_to：
FEBS Open Bio
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