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嘌呤霉素二盐酸盐
CAS:No.58-58-2
英文名称:Puromycin dihydrochloride
分子式:C22H31Cl2N7O5
分子量:544.43
储存条件:Powder:-20℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
纯度:HPLC≥98%
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产品简介
| CAS | No.58-58-2 |
| 中文名称 | 嘌呤霉素二盐酸盐 |
| 英文名称 | Puromycin dihydrochloride |
| 别名 | 嘌呤霉素二盐酸盐水合物;CL13900 dihydrochloride |
| 分子式 | C22H31Cl2N7O5 |
| 分子量 | 544.43 |
| 溶解性 | Soluble in Water ≥5mg/mL |
| 纯度 | HPLC≥98% |
| 外观(性状) | White to light yellow Solid |
| 储存条件 | Powder:-20℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-387-8 |
| MDL | MFCD00012691 |
| SMILES | OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O.[H]Cl.[H]Cl |
| 靶点 | Bacterial |
| 通路 | Anti-infection |
| 背景说明 | Puromycin是一种抑制 protein synthesis 的氨基糖苷类抗生素。 |
| 生物活性 | Puromycin dihydrochloride是嘌呤霉素的二盐酸盐。 Puromycin是一种抑制 protein synthesis 的氨基糖苷类抗生素。[1-3] |
| In Vitro | 嘌呤霉素在氨酰基-sRNA形成后阻断蛋白质合成，同时它导致小肽的积累。这两种效应似乎都是由于核糖体结合的肽基-sRNA的分裂，导致不完整肽链的释放[1]。嘌呤霉素是氨酰基-tRNA的3末端的类似物，通过与生长的多肽链非特异性连接而导致翻译过早终止。嘌呤霉素具有两种抑制作用模式。第一种是通过作为受体底物，其攻击P位点中的肽基-tRNA以形成新生肽。第二种是通过与氨酰基-tRNA竞争结合A位点[2]。当以最小量使用时，嘌呤霉素掺入新合成的蛋白质直接反映体外mRNA翻译的速率。嘌呤霉素免疫检测是放射性氨基酸标记的有利替代方案。它允许通过免疫荧光显微镜直接评估单细胞中的翻译活性，并通过荧光激活细胞分选直接评估异质细胞群[3]。 |
| 数据来源文献 |
[1]. Nathans D， et al. Puromycin inhibition of protein synthesis: incorporation of puromycin intopeptide chains. Proc Natl Acad Sci U S A. 1964 Apr;51:585-92. [2]. Miyamoto-Sato E， et al. Specific bonding of puromycin to full-length protein at the C-terminus. Nucleic Acids Res. 2000 Mar 1;28(5):1176-82. [3]. Schmidt EK， et al. SUnSET， a nonradioactive method to monitor protein synthesis. Nat Methods. 2009 Apr;6(4):275-7 |
| 规格 | 5mg 10mM*1mL in Water 10mg 25mg |
| 单位 | 支 |
Puromycin是一种抑制 protein synthesis 的氨基糖苷类抗生素。
使用本产品的应用案例（仅供参考）
In Vitro
Cell（OC cells，2 μg/mL puromycin）
Cell（A549 and PC-9 cells，2 mg/mL puromycin）
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
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Hu Anling, Gao Jian, Varier Krishnapriya M., Gajendran Babu, Jiang Fei, Liu Wuling, Wang Chunlin, Xiao Xiao, Li Yanmei, Zacksenhaus Eldad, Ali Sajjad, Ben-David Yaacov
IF：
7.1090
Publish_to：
Cell Death Discovery
PMID：
36335089
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer
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Author：
Wang Shanshan, Wang Taishu, Yang Qianyi, Cheng Shaoxuan, Liu Fang, Yang Guoheng, Wang Fuqiang, Wang Ruilin, Yang Dian, Zhou Mingyu, Duan Chengen, Zhang Yingqiu, Liu Han, Dai Zhaoxia, Tian Kang, Liu Shuyan
IF：
7.0510
Publish_to：
CELLULAR ONCOLOGY
PMID：
36129611
Verteporfin reverses progestin resistance through YAP/TAZ-PI3K-Akt pathway in endometrial carcinoma
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Author：
Wei Lina, Ma Xiaohong, Hou Yixin, Zhao Tianyi, Sun Rui, Qiu Chunping, Liu Yao, Qiu Ziyi, Liu Zhiming, Jiang Jie
IF：
7.0000
Publish_to：
Cell Death Discovery
PMID：
36693834
Schwann cells promote prevascularization and osteogenesis of tissue-engineered bone via bone marrow mesenchymal stem cell-derived endothelial cells
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Author：
Zhang Xinxin, Jiang Xiaorui, Jiang Shan, Cai Xiyu, Yu Shengji, Pei Guoxian
IF：
6.8320
Publish_to：
Stem Cell Research & Therapy
PMID：
34233721
Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway
点击查看 >>
Author：
Tianfeng Yang, Cheng Cheng, Rui Xu, Jian Huo, Xiujuan Peng, Yanbin Chen, Yonghong Liang, Zhiheng Su, Yanmin Zhang
IF：
6.7800
Publish_to：
LIFE SCIENCES
PMID：
36257459
Loss of ARID1A expression promotes lung adenocarcinoma metastasis and predicts a poor prognosis
点击查看 >>
Author：
Sun Dantong, Zhu Yan, Zhao Han, Bian Tiantian, Li Tianjun, Liu Kewei, Feng Lizong, Li Hong, Hou Helei
IF：
6.7300
Publish_to：
CELLULAR ONCOLOGY
PMID：
34109546
Ca2+ transfer via the ER-mitochondria tethering complex in neuronal cells contribute to cadmium-induced autophagy
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Author：
Wang Tao, Zhu Qiaoping, Cao Binbin, Cai Yao, Wen Shuangquan, Bian Jianchun, Zou Hui, Song Ruilong, Gu Jianhong, Liu Xuezhong, Liu Zongping, Yuan Yan
IF：
6.6910
Publish_to：
CELL BIOLOGY AND TOXICOLOGY
PMID：
34308505
CircGLIS3 Promotes High-Grade Glioma Invasion via Modulating Ezrin Phosphorylation
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Author：
Li Yan, Chen Jiansheng, Chen Zetao, Xu Xiangdong, Weng Jun, Zhang Yuxuan, Mo Yunzhao, Liu Yang, Wang Jihui, Ke Yiquan
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
34540823
6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br. (Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic cancer cells through the disruption of oxaloacetic acid metabolism and accumulation of reactive
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Author：
Nengfang Ma, Fugen Shangguan, Hongfei Zhou, Huimin Huang, Jun Lei, Jing An, Guihua Jin, Weiwei Zhuang, Shipeng Zhou, Shijia Wu, Hongping Xia, Hailong Yang, Linhua Lan
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
35597026
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition
点击查看 >>
Author：
Yuexian Li, Cheng Sun, Yonggang Tan, Heying Zhang, Yuchao Li, Huawei Zou
IF：
6.5820
Publish_to：
International Journal of Biological Sciences
PMID：
33613118
IFI35 Promotes Renal Cancer Progression by Inhibiting pSTAT1/pSTAT6-Dependent Autophagy
点击查看 >>
Author：
Dafei Chai, Shang Yuchen Shi, Navid Sobhani, Jiage Ding, Zichun Zhang, Nan Jiang, Gang Wang, Minle Li, Hailong Li, Junnian Zheng, Jin Bai
IF：
6.5750
Publish_to：
Cancers
PMID：
35740527
Pharmic Activation of PKG2 Alleviates Diabetes-Induced Osteoblast Dysfunction by Suppressing PLCβ1-Ca2+-Mediated Endoplasmic Reticulum Stress
点击查看 >>
Author：
Tingting Jia, Ya-nan Wang, Yao Feng, Chenchen Wang, Dongjiao Zhang, Xin Xu
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
34221234
Curcumin suppresses the malignancy of non-small cell lung cancer by modulating the circ-PRKCA/miR-384/ITGB1 pathway
点击查看 >>
Author：
Xiaoqing Xu, Xinyue Zhang, Yang Zhang, Zhipeng Wang
IF：
6.5300
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
33684690
Circular RNA circ_IRAK3 contributes to tumor growth through upregulating KIF2A via adsorbing miR-603 in breast cancer
点击查看 >>
Author：
Wang Fang, Li Jingruo, Li Lin, Chen Zhuo, Wang Nan, Zhu Mingzhi, Mi Hailong, Xiong Youyi, Guo Guangcheng, Gu Yuanting
IF：
6.4290
Publish_to：
Cancer Cell International
PMID：
35164763
SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1
点击查看 >>
Author：
Wang Yanting, Ren Xianyue, Li Weiyu, Cao Ruoyan, Liu Suyang, Jiang Laibo, Cheng Bin, Xia Juan
IF：
6.3440
Publish_to：
International Journal of Oral Science
PMID：
34667150
SMAD-specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis
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Author：
Ma Mengjun, Yang Wen, Cai Zhaopeng, Wang Peng, Li Hongyu, Mi Rujia, Jiang Yuhang, Xie Zhongyu, Sui Pengfei, Wu Yanfeng, Shen Huiyong
IF：
6.2770
Publish_to：
STEM CELLS
PMID：
33547700
Metformin Downregulates PD-L1 Expression in Esophageal Squamous Cell Carcinoma by Inhibiting IL-6 Signaling Pathway
点击查看 >>
Author：
Lu Yao, Xin Dao, Guan Lulu, Xu Mengli, Yang Yalan, Chen Yu, Yang Yuanyuan, Wang-Gillam Andrea, Wang Li, Zong Shanggang, Wang Feng
IF：
6.2440
Publish_to：
Frontiers in Oncology
PMID：
34881181
Modulating p-AMPK/mTOR Pathway of Mitochondrial Dysfunction Caused by MTERF1 Abnormal Expression in Colorectal Cancer Cells
点击查看 >>
Author：
Qianqian Liu, Longlong Zhang, Yayan Zou, Ying Tao, Bing Wang, Bin Li, Ruai Liu, Boyong Wang, Lei Ding, Qinghua Cui, Jie Lin, Bingyu Mao, Wei Xiong, Min Yu
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36293209
PDGF-D Prodomain Differentially Inhibits the Biological Activities of PDGF-D and PDGF-B
点击查看 >>
Author：
Linli Li, Dan Wu, Xiaohong Qin, Li-Zhi Mi
IF：
6.1510
Publish_to：
JOURNAL OF MOLECULAR BIOLOGY
PMID：
35777468
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11
点击查看 >>
Author：
Yin Yan-ping, Ma Li-ying, Cao Guo-zhen, Hua Jing-han, Lv Xiao-tong, Lin Wen-chu
IF：
6.1500
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
34893686
The mtDNA-STING pathway plays an important role in both navitoclax- and S63845-induced autophagy and enhances cell death
点击查看 >>
Author：
Jia Jia, Li Mengqing, Li Yunjian, Xiao Jun, Dai Haiming
IF：
6.1000
Publish_to：
CELL BIOLOGY AND TOXICOLOGY
PMID：
37002446
METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma
点击查看 >>
Author：
Lu Liting, Zheng Dandan, Qu Junchi, Zhuang Yanyan, Peng Juanfei, Lan Sihua, Zhang Shineng, Huang Fengting
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
36158188
Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis
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Author：
Wenli Gu, Xiao Jiang, Wei Wang, Prabhakar Mujagond, Jingpeng Liu, Zhaoyi Mai, Hai Tang, Simin li, Hui Xiao, Jianjiang Zhao
IF：
6.0550
Publish_to：
Frontiers in Endocrinology
PMID：
35663324
Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/β-catenin signaling pathway
点击查看 >>
Author：
Jue Wang; Nanning Sheng; Ying Li; Yawei Fan; Xinro
IF：
5.9420
Publish_to：
American Journal of Cancer Research
PMID：
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death
点击查看 >>
Author：
Longbin Zhang, Liyong Zou, Xuejun Jiang, Shuqun Cheng, Jun Zhang, Xia Qin, Zhexue Qin, Chengzhi Chen, Zhen Zou
IF：
5.9130
Publish_to：
Nanotoxicology
PMID：
33971103
Biotransformation of American Ginseng Stems and Leaves by an Endophytic Fungus Umbelopsis sp. and Its Effect on Alzheimer’s Disease Control
点击查看 >>
Author：
Qiqi Chen, Jingying Wang, Yuhang Gao, Zixin Wang, Xiujun Gao, Peisheng Yan
IF：
5.9000
Publish_to：
Nutrients
PMID：
38068736
Synergistic effect of toosendanin and regorafenib against cell proliferation and migration by regulating WWOX signaling pathway in hepatocellular carcinoma
点击查看 >>
Author：
Tianfeng Yang, Jian Huo, Rui Xu, Yanmin Zhang
IF：
5.8820
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
34058790
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin
点击查看 >>
Author：
Xiao Guan, Dan Yu, Mengjie HuangFu, Zhiyi Huang, Tong Dou, Yisa Liu, Luwei Zhou, Xumei Li, Lin Wang, Haiping Liu, Juan Wang, Xu Chen
IF：
5.8580
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
34428442
Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4
点击查看 >>
Author：
Hu Tianzhen, Pan Chengyun, Zhang Tianzhuo, Ni Ming, Wang Weili, Zhang Siyu, Chen Ying, Wang Jishi, Fang Qin
IF：
5.8540
Publish_to：
CANCER GENE THERAPY
PMID：
35840666
Telmisartan Potentiates Insulin Secretion via Ion Channels, Independent of the AT1 Receptor and PPARγ
点击查看 >>
Author：
Liu Tao, Cui Lijuan, Xue Huan, Yang Xiaohua, Liu Mengmeng, Zhi Linping, Yang Huanhuan, Liu Zhihong, Zhang Min, Guo Qing, He Peifeng, Liu Yunfeng, Zhang Yi
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34594226
Paris saponins Ⅶ inhibits glycolysis of ovarian cancer via the RORC/ACK1 signaling pathway
点击查看 >>
Author：
Wu Z; Yuan C; Zhang Z; Wang M; Xu M; Chen Z; Tian J; Cao W; Wang Z.
IF：
5.8000
Publish_to：
Biochemical Pharmacology
PMID：
37196681
Proteoglycan-4 predicts good prognosis in patients with hepatocellular carcinoma receiving transcatheter arterial chemoembolization and inhibits cancer cell migration in vitro
点击查看 >>
Author：
Guo Yuan, Hu Hong Tao, Xu Shi Jun, Xia Wei Li, Zhao Yan, Zhao Xiao Hui, Zhu Wen Bo, Li Fang Ting, Li Hai Liang
IF：
5.7380
Publish_to：
Frontiers in Oncology
PMID：
36439456
Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells
点击查看 >>
Author：
Lai Weixin, Li Xinyu, Kong Qian, Chen Han, Li Yunyao, Xu Lu-Hong, Fang Jianpei
IF：
5.7220
Publish_to：
Cancer Cell International
PMID：
34933679
A novel small molecule Hsp90 inhibitor, C-316-1, attenuates acute kidney injury by suppressing RIPK1-mediated inflammation and necroptosis
点击查看 >>
Author：
Xue-qi Liu, Ming-ming Liu, Ling Jiang, Li Gao, Yao Zhang, Yue-bo Huang, Xian Wang, Wei Zhu, Han-xu Zeng, Xiao-ming Meng, Yong-gui Wu
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
35588657
Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo
点击查看 >>
Author：
Yuan Xingyu, Duan Xianlan, Li Zhao, Yao Bin, Enhejirigala Enhejirigala, Song Wei, Kong Yi, Wang Yuzhen, Zhang Fanliang, Liang Liting, Zhu Shijun, Zhang Mengde, Zhang Chao, Huang Sha, Fu Xiaobing
IF：
5.7110
Publish_to：
Burns & Trauma
PMID：
35937591
CRISPR/Cas9-mediated knockout of STAT1 in porcine-derived cell lines to elucidate the role of STAT1 in autophagy following classical swine fever virus infection
点击查看 >>
Author：
Liyuan Zhang, Dongli Liang, Kaijun Min, Jiaxin Liang, Yu Tian, Cheng Liu, Ting Rong Luo, Xiaoning Li
IF：
5.7000
Publish_to：
Frontiers in Immunology
PMID：
39539545
UNC5B Overexpression Alleviates Peripheral Neuropathic Pain by Stimulating Netrin-1-Dependent Autophagic Flux in Schwann Cells
点击查看 >>
Author：
Xiao Pei-yao, Chen Jing-yan, Zeng Qing, Huang Zi, Huang Bei-xu, Yu Jian, Liao Song-jie
IF：
5.6820
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
35668343
Taurine Alleviates Cadmium-Induced Hepatotoxicity by Regulating Autophagy Flux
点击查看 >>
Author：
Yuntian Duan, Yumeng Zhao, Tao Wang, Jian Sun, Waseem Ali, Yonggang Ma, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zou
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36674718
Cyclovirobuxine D Induced-Mitophagy through the p65/BNIP3/LC3 Axis Potentiates Its Apoptosis-Inducing Effects in Lung Cancer Cells
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Author：
ZengC;ZouT;QuJ;ChenX;ZhangS;LinZ
IF：
5.5420
Publish_to：
Int J Mol Sci
PMID：
34072333
Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer
点击查看 >>
Author：
Liu Jia, Li Jingyi, Sun Zhao, Duan Yangmiao, Wang Fengqin, Wei Guangwei, Yang Jing-Hua
IF：
5.5310
Publish_to：
Journal of Translational Medicine
PMID：
34372878
A C21-steroidal derivative suppresses T-cell lymphoma in mice by inhibiting SIRT3 via SAP18-SIN3
点击查看 >>
Author：
Gajendran B;Varier KM;Liu W;Wang C;Sample KM;Zacks
IF：
5.4890
Publish_to：
Commun Biol.
PMID：
33273692
HRD1 Promotes Non-small Cell Lung Carcinoma Metastasis by Blocking Autophagy-mediated MIEN1 Degradation
点击查看 >>
Author：
Cheng Zeng, Jing Guo, Jiajia Wu, Tiantian Che, Xiaoping Huang, Huawen Liu, Zhenghong Lin
IF：
5.4860
Publish_to：
JOURNAL OF BIOLOGICAL CHEMISTRY
PMID：
37075843
Microarray profiling identifies hsa_circ_0082003 as a novel tumor promoter for papillary thyroid carcinoma
点击查看 >>
Author：
Ye J., Feng J.-W., Wu W.-X., Qi G.-F., Wang F., Hu J., Hong L.-Z., Liu S.-Y., Jiang Y.
IF：
5.4670
Publish_to：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
PMID：
36115894
IL-37 overexpression enhances the therapeutic effect of endometrial regenerative cells in concanavalin A-induced hepatitis
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Author：
Guangming Li, Dejun Kong, Yafei Qin, Hongda Wang, Yonghao Hu, Yiming Zhao, Jingpeng Hao, Hong Qin, Dingding Yu, Yanglin Zhu, Chenglu Sun, Hao Wang
IF：
5.4140
Publish_to：
CYTOTHERAPY
PMID：
33593687
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway
点击查看 >>
Author：
Jin-Jin Zhang, Chang-Xiong Cao, Li-Lan Wan, Wen Zhang, Zhong-Jiang Liu, Jin-Li Wang, Qiang Guo, Hui Tang
IF：
5.3740
Publish_to：
WORLD JOURNAL OF GASTROENTEROLOGY
PMID：
35633908
A Positron Emission Tomography Tracer Targeting the S2 Subunit of SARS-CoV-2 in Extrapulmonary Infections
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Author：
Jianzhong Xian, Hongbin Huang, Guolong Huang, Renwei Zhou, Min Yang, Yifan Qiu, Lei Bi, Zhongzhen Su, Fei Xiao, Hong Shan, Hongjun Jin
IF：
5.3640
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
36067000
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling
点击查看 >>
Author：
Xiang Zhou, Weiming Wang, Zhaofeng Li, Lin Chen, Chunmei Wen, Qingqing Ruan, Zheng Xu, Rongdiao Liu, Jinzhong Xu, Yongheng Bai, Jie Deng
IF：
5.3400
Publish_to：
PHYTOMEDICINE
PMID：
34864627
LncRNA PVT1 promotes the progression of ovarian cancer by activating TGF-β pathway via miR-148a-3p/AGO1 axis
点击查看 >>
Author：
Yuxian Wu, Wenqian Gu, Xiao Han, Zhijun Jin
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
34288373
PBRM1 deficiency oncogenic addiction is associated with activated AKT–mTOR signalling and aerobic glycolysis in clear cell renal cell carcinoma cells
点击查看 >>
Author：
Yu Tang, Yan-Hong Jin, Hu-Li Li, Hui Xin, Jin-Dong Chen, Xue-Ying Li, You-Fu Pan
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
35672925
L-Arginine/nitric oxide regulates skeletal muscle development via muscle fibre-specific nitric oxide/mTOR pathway in chickens
点击查看 >>
Author：
Ruxia Wang, Kelin Li, Li Sun, Hongchao Jiao, Yunlei Zhou, Haifang Li, Xiaojuan Wang, Jingpeng Zhao, Hai Lin
IF：
5.2850
Publish_to：
Animal Nutrition
PMID：
35647326
Modulating DHA-Producing Schizochytrium sp. toward Astaxanthin Biosynthesis via a Seamless Genome Editing System
点击查看 >>
Author：
Peng-Yang Liu, Gang Li, Chu-Bin Lin, Jun-Jie Wu, Shan Jiang, Feng-Hong Huang, Xia Wan
IF：
5.2490
Publish_to：
ACS Synthetic Biology
PMID：
36454215
RIPK4 Suppresses the Invasion and Metastasis of Hepatocellular Carcinoma by Inhibiting the Phosphorylation of STAT3
点击查看 >>
Author：
Li Haoran, Luo Dingan, Huttad Lakshmi, Zhang Mao, Wang Youpeng, Feng Juan, Ding Yunfeng, Han Bing
IF：
5.2460
Publish_to：
Frontiers in Molecular Biosciences
PMID：
34222329
CircMYOF triggers progression and facilitates glycolysis via the VEGFA/PI3K/AKT axis by absorbing miR-4739 in pancreatic ductal adenocarcinoma
点击查看 >>
Author：
Zheng Dandan, Huang Xianxian, Peng Juanfei, Zhuang Yanyan, Li Yuanhua, Qu Junchi, Zhang Shineng, Huang Fengting
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
34811346
Upregulated microRNA let-7a accelerates apoptosis and inhibits proliferation in uterine junctional zone smooth muscle cells in adenomyosis under conditions of a normal activated hippo-YAP1 axis
点击查看 >>
Author：
Huang Jun-Hua, Duan Hua, Wang Sha, Wang Yi-Yi, LV Cheng-Xiao
IF：
5.2110
Publish_to：
Reproductive Biology and Endocrinology
PMID：
34082774
Leveraging Tumor Microenvironment Infiltration in Pancreatic Cancer to Identify Gene Signatures Related to Prognosis and Immunotherapy Response
点击查看 >>
Author：
Jiabin Yang, Liangtang Zeng, Ruiwan Chen, Leyi Huang, Zhuo Wu, Min Yu, Yu Zhou, Rufu Chen
IF：
5.2000
Publish_to：
Cancers
PMID：
36900234
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma
点击查看 >>
Author：
Ke Huang, Huihui Wang, Jia Xu, Ruiming Xu, Zelin Liu, Yi Li, Zhaoqing Xu
IF：
5.1680
Publish_to：
Biology-Basel
PMID：
35892971
Immortalized Mesenchymal Stem Cells: A Safe Cell Source for Cellular or Cell Membrane-Based Treatment of Glioma
点击查看 >>
Author：
Yuxuan Zhang, Jie Liu, Yunzhao Mo, Zetao Chen, Taoliang Chen, Yan Li, Yaofeng Zheng, Shaokang Deng, Xiangdong Xu, Huajian Chen, Haoqi He, Jiansheng Chen, Tao Jin, Xinlin Sun, Yiquan Ke, Jihui Wang
IF：
5.1310
Publish_to：
Stem Cells International
PMID：
35463812
LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma
点击查看 >>
Author：
Xin Fang, Li-Hua Ren, Sachin Mulmi Shrestha, Qinghua Ji, Zeyan Xu, Dan Wang, Qitao Ding, Xiao Liang, Rui-hua Shi
IF：
5.1000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
PMID：
36990227
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells
点击查看 >>
Author：
Xixi Chen, Liping Wang, Xiao Yu, Shujing Wang, Jianing Zhang
IF：
5.0850
Publish_to：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
PMID：
34157397
Loss of receptor tyrosine kinase-like orphan receptor 2 impairs the osteogenesis of mBMSCs by inhibiting signal transducer and activator of transcription 3
点击查看 >>
Author：
LeiL;HuangZ;FengJ;HuangZ;TaoY;HuX;ZhangX
IF：
5.0810
Publish_to：
Stem Cell Res Ther
PMID：
32216811
MicroRNA-34b-5p binds enhancer of zeste 2 to inhibit milk fat globule-EGF factor 8 expression, affecting liver fibrosis
点击查看 >>
Author：
Ma Jing, Liu Qiyao, Chen Mengxuan, He Bo, Li Yi, Zhang Min, Jiang Yongfang
IF：
5.0800
Publish_to：
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
PMID：
36138295
Cascaded microfluidic circuits for pulsatile filtration of extracellular vesicles from whole blood for early cancer diagnosis
点击查看 >>
Author：
Li Z; Liu C; Cheng Y; Li Y; Deng J; Bai L; Qin L; Mei H; Zeng M; Tian F; Zhang S; Sun J.
IF：
5.0000
Publish_to：
Science Advances
PMID：
37083528
Dynamic expression of Mage-D1 in rat dental germs and potential role in mineralization of ectomesenchymal stem cells
点击查看 >>
Author：
Li Meng, Yu Xia, Luo Yuting, Yuan Hongyan, Zhang Yixing, Wen Xiujie, zhou Zhi
IF：
4.9960
Publish_to：
Scientific Reports
PMID：
36585447
CtBP1 Mediates Hypoxia-Induced Sarcomatoid Transformation in Hepatocellular Carcinoma
点击查看 >>
Author：
Xiaoling Zhang, Xiaoyu Wang, Liting Jia, Yang Yang, Fan Yang, Shengjun Xiao
IF：
4.9620
Publish_to：
Journal of Hepatocellular Carcinoma
PMID：
35186805
A Novel Therapeutic Tumor Vaccine Targeting MUC1 in Combination with PD-L1 Elicits Specific Anti-Tumor Immunity in Mice
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Author：
Jiayi Pan, Wuyi Zeng, Jiangtao Jia, Yi Shi, Danni Wang, Jun Dong, Zixuan Fang, Jiashan He, Xinyu Yang, Rong Zhang, Menghua He, Maoping Huang, Bishi Fu, Bei Zhong, Hui Liu
IF：
4.9610
Publish_to：
Vaccines
PMID：
35891256
circCRKL. a circRNA derived from CRKL. regulates BCR-ABL via sponging miR-877-5p to promote chronic myeloid leukemia cell proliferation
点击查看 >>
Author：
Wang J. Liang Y. Qin Y. Jiang G. Peng Y. Feng W
IF：
4.9560
Publish_to：
J Transl Med
PMID：
36058922
124I-Labeled Immuno-PET Targeting hTREM2 for the Diagnosis of Gastric Carcinoma
点击查看 >>
Author：
Dai Shi, Zhan Xu, Yuan Cheng, Qingyu Lin, Zhan Si, Wenhui Fu, Tingting Yang, Hongcheng Shi, Dengfeng Cheng
IF：
4.9000
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
36951296
FLI1 regulates inflammation-associated genes to accelerate leukemogenesis
点击查看 >>
Author：
Beiling Chen, Danmei Sheng, Chunlin Wang, Wuling Liu, Anling Hu, Xiao Xiao, Babu Gajendran, Jian Gao, Jifen Hu, Klarke M. Sample, Eldad Zacksenhaus, Yaacov Ben-David
IF：
4.8500
Publish_to：
CELLULAR SIGNALLING
PMID：
35104574
LncRNA MEG3 Involved in NiO NPs-Induced Pulmonary Fibrosis via Regulating TGF-β1-Mediated PI3K/AKT Pathway
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Author：
Zhan Haibing, Sun Xingchang, Wang Xiaoxia, Gao Qing, Yang Mengmeng, Liu Han, Zheng Jinfa, Gong Xuefeng, Feng Sanwei, Chang Xuhong, Sun Yingbiao
IF：
4.8490
Publish_to：
TOXICOLOGICAL SCIENCES
PMID：
33895847
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition
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Author：
Dong P. Fu H. Chen L. Zhang S. Zhang X. Li H. Wu D
IF：
4.8290
Publish_to：
J Cell Mol Med
PMID：
32548978
Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR
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Author：
Jun Ren, Zhiqing Hu, Gengming Niu, Jie Xia, Xing Wang, Runqi Hong, Jiawei Gu, Daorong Wang, Chongwei Ke
IF：
4.8000
Publish_to：
FASEB JOURNAL
PMID：
36786694
MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation
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Author：
Bingjie Cai, Min Li, Yunpeng Zheng, Yakun Yin, Fangcao Jin, Xuyang Li, Juan Dong, Xiaoyan Jiao, Xiaojun Liu, Kun Zhang, Dongqin Li, Junmin Wang, Guangwen Yin
IF：
4.7930
Publish_to：
HUMAN GENE THERAPY
PMID：
35171714
The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation
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Author：
Liu Chao; Du Jiang; Zheng Jianwei; Zhang Ruizhe; Z
IF：
4.7000
Publish_to：
Frontiers in Oncology
PMID：
37377917
SNCA correlates with immune infiltration and serves as a prognostic biomarker in lung adenocarcinoma
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Author：
Zhang Xiuao, Wu Zhengcun, Ma Kaili
IF：
4.6380
Publish_to：
BMC CANCER
PMID：
35421944
Icariin Promotes Osteogenic Differentiation in a Cell Model with NF1 Gene Knockout by Activating the cAMP/PKA/CREB Pathway
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Author：
Meng Chen; Lianhua Lu; Dong Cheng; Jing Zhang; Xin
IF：
4.6000
Publish_to：
MOLECULES
PMID：
37446790
Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis
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Author：
Rongyan Qin, Fengque Zheng, Weili Qin, Jiawei Wang, Nana Ma, Wencai Tian, Jiaxu Li, Ming Liao, Aiping Qin
IF：
4.5670
Publish_to：
REPRODUCTIVE BIOMEDICINE ONLINE
PMID：
36604215
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening
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Author：
DengL;YangL;ZhuS;LiM;WangY;CaoX;WangQ;GuoL
IF：
4.5300
Publish_to：
Cell Death Discov
PMID：
36725843
Ultrasound-targeted microbubbles destruction assists dual delivery of beta-amyloid antibody and neural stem cells to restore neural function in transgenic mice of Alzheimer's disease
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Author：
Qiong Zhu, Xiaoxun Xu, Beibei Chen, Yiyi Liao, Xue Guan, Ying He, Hai Cui, Yani Rong, Zheng Liu, Yali Xu
IF：
4.5060
Publish_to：
MEDICAL PHYSICS
PMID：
35092698
FLI1 Regulates Histamine Decarboxylase Expression to Control Inflammation Signaling and Leukemia Progression
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Author：
Jifen Hu; Jian Gao; Chunlin Wang; Wuling Liu; Anli
IF：
4.5000
Publish_to：
Journal of Inflammation Research
PMID：
37193069
Study on the Prognostic Values of TTC36 Correlated with Immune Infiltrates and Its Methylation in Hepatocellular Carcinoma
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Author：
Wei Jing, Ruoyu Peng, Xiaogai Li, Shaogang Lv, Yu Duan, Shitao Jiang
IF：
4.4930
Publish_to：
Journal of Immunology Research
PMID：
35846428
Integrative analysis regarding the correlation between GAS2 family genes and human glioma prognosis
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Author：
Chunyan Zhao, Nan Zhang, Xiaoteng Cui, Xinxin Zhang, Yuanyuan Ren, Chao Su, Jinyan He, Wei Zhang, Xiaoming Sun, Jie Yang, Xingjie Gao
IF：
4.4520
Publish_to：
Cancer Medicine
PMID：
33713047
ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes
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Author：
Yu Fang, Gajendran Babu, Wang Ning, Sample Klarke M., Liu Wuling, Wang Chunlin, Hu Anling, Zacksenhaus Eldad, Hao Xiaojiang, Ben-David Yaacov
IF：
4.4300
Publish_to：
BMC CANCER
PMID：
34107900
PXR-mediated expression of FABP4 promotes valproate-induced lipid accumulation in HepG2 cells
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Author：
Liang Yan, Kun Yang, Suhua Wang, Yinfei Xie, Lirong Zhang, Xin Tian
IF：
4.3740
Publish_to：
TOXICOLOGY LETTERS
PMID：
33901630
Profiling and integrated analysis of differentially expressed circRNAs in cervical cancer
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Author：
Li Yuan, Chunyu Zhang, Jiaying Li, Yuandong Liao, Hua Huang, Yuwen Pan, Qiqiao Du, Yili Chen, Wei Wang, Shuzhong Yao
IF：
4.3100
Publish_to：
GENOMICS
PMID：
35724730
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer
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Author：
Ouxuan Liu, Caixia Wang, Shuang Wang, Yuexin Hu, Rui Gou, Hui Dong, Siting Li, Xiao Li, Bei Lin
IF：
4.2070
Publish_to：
Journal of Cancer
PMID：
34659572
LncRNA LINC01094 contributes to glioma progression by modulating miR-224-5p/CHSY1 axis
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Author：
Liu Luotong, Xu Qian, Xiong Yu, Deng Huajiang, Zhou Jie
IF：
4.1740
Publish_to：
Human Cell
PMID：
34716872
Ventilagolin Suppresses Migration, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells by Downregulating Pim-1
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Author：
Ying Liu, Dao-Hai Cheng, Ke-Dao Lai, Hua Su, Guo-Shou Lu, Li Wang, Ji-Hua Lv
IF：
4.1620
Publish_to：
Drug Design Development and Therapy
PMID：
34880599
ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes
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Author：
Rui-zhe Li, Yun-yun Li, Hui Qin, Shan-shan Li
IF：
4.1470
Publish_to：
OncoTargets and Therapy
PMID：
33469301
Polyamine synthesis enzyme AMD1 is closely related to the tumorigenesis and prognosis of human breast cancer
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Author：
Hongyu Gao, Hanjun Li, Jingjie Wang, Cheng Xu, Yueyun Zhu, Dilihumaer Tuluhong, Xinfang Li, Shaohua Wang, Jieshou Li
IF：
4.1450
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
35671837
LncRNA MEG3 mediates nickel oxide nanoparticles-induced pulmonary fibrosis via suppressing TGF-β1 expression and epithelial-mesenchymal transition process
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Author：
Haibing Zhan, Xuhong Chang, Xiaoxia Wang, Mengmeng Yang, Qing Gao, Han Liu, Chengyun Li, Sheng Li, Yingbiao Sun
IF：
4.1190
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
33547861
Parvalbumin in the metabolic pathway of glutamate and γ-aminobutyric acid: Influence on expression of GAD65 and GAD67
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Author：
Chunmei Zeng, Danqing Lei, Yuling Lu, Qi Huang, Ying Wu, Shengyu Yang, Yuan Wu
IF：
4.1140
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
36587827
Hsa_circ_0001944 regulates apoptosis by regulating the binding of PARP1 and HuR in leukemia and malignant transformed cells induced by hydroquinone
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Author：
Bohuan Zhong, Xiaoxuan Ling, Jinxue Meng, Yali Han, Haiqiao Zhang, Zhidong Liu, Jialong Chen, He Zhang, Zhijie Pan, Linhua Liu
IF：
4.1090
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
36448377
Development and characterization of in vitro self-assembled recombinant human follicle stimulating hormone originated from goat mammary epithelial cells
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Author：
Rongmao Hua, Jianyong Cheng, Li Yang, Zelin Zhang, Dejun Xu, Huali Chen, Yuan Li, Jiaxin Duan, Xiaoya Li, Guoxia Geng, Jianxi Liu, Qingwang Li
IF：
4.1020
Publish_to：
MOLECULAR AND CELLULAR ENDOCRINOLOGY
PMID：
33582214
HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA
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Author：
Lei Ke, Sun Mingyue, Chen Xianghan, Wang Jia, Liu Xiaolan, Ning Ying, Ping Shuai, Gong Ruining, Zhang Yu, Qing Gong, Zhao Chenyang, Ren He
IF：
4.1000
Publish_to：
MOLECULAR CANCER RESEARCH
PMID：
38967522
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway
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Author：
Kui Xiang, Hua Yanshan, Zhao Chunmei, Guo Minmin, Wang Yan, Yi Xiaojia
IF：
4.0880
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
PMID：
35880886
Periostin regulates LPS-induced apoptosis via Nrf2/HO-1 pathway in periodontal ligament fibroblasts
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Author：
Yujun Jiang, Panpan Yang, Congshan Li, Yupu Lu, Yuying Kou, Hongrui Liu, Jie Guo, Minqi Li
IF：
4.0680
Publish_to：
ORAL DISEASES
PMID：
35298860
LncRNA LINC01088 inhibits the function of trophoblast cells, activates the MAPK-signaling pathway and associates with recurrent pregnancy loss
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Author：
Zhao Hui, Li Yali, Dong Nana, Zhang Lei, Chen Xi, Mao Huihui, Al-Ameri Samed Ahmed Al-Ezzi, Wang Xiaoling, Wang Qun, Du Lutao, Wang Chuanxin, Mao Haiting
IF：
4.0250
Publish_to：
MOLECULAR HUMAN REPRODUCTION
PMID：
34264302
Circular RNA circDNM3OS Functions as a miR-145-5p Sponge to Accelerate Cholangiocarcinoma Growth and Glutamine Metabolism by Upregulating MORC2
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Author：
Yongfeng Su, Ting Yu, Yaqi Wang, Xianming Huang, Xiaoyong Wei
IF：
4.0000
Publish_to：
OncoTargets and Therapy
PMID：
33628035
Overexpression of NMNAT3 improves mitochondrial function and enhances antioxidative stress capacity of bone marrow mesenchymal stem cells via the NAD+-Sirt3 pathway
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Author：
Wang Tao, Zhang Fei, Peng Wuxun, Wang Lei, Zhang Jian, Dong Wentao, Tian Xiaobin, Ye Chuan, Li Yanlin, Gong Yuekun
IF：
3.9760
Publish_to：
BIOSCIENCE REPORTS
PMID：
34981121
Upregulation of PAIP1 promotes the gallbladder tumorigenesis through regulating PLK1 level
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Author：
Jianping Bi, Hong Ma, Yafei Liu, Ai Huang, Yong Xiao, Wen-Jie Shu, Haining Du, Tao Zhang
IF：
3.9320
Publish_to：
Annals of Translational Medicine
PMID：
34277791
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer
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Author：
Yingjie Gao, Guangliang Zhang, Jinlong Liu, Huimin Li
IF：
3.9060
Publish_to：
ONCOLOGY REPORTS
PMID：
33760213
HNRNPU promotes the progression of hepatocellular carcinoma by enhancing CDK2 transcription
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Author：
Yi Liang, Yao Fan, Yu Liu, Hui Fan
IF：
3.9050
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
34737140
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway
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Author：
Yuhan Jiao, Ming Xin, Juanjuan Xu, Xindong Xiang, Xuan Li, Jingjing Jiang, Xiuqin Jia
IF：
3.8890
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
36102594
Wnt5a regulates autophagy in Bacille Calmette-Guérin (BCG)-Infected pulmonary epithelial cells
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Author：
Qi Chen, Xuedi Zheng, Yong Li, Boli Ma, Xueyi Nie, Mengyuan Li, Yueyang Liu, Jinrui Xu, Yi Yang
IF：
3.8480
Publish_to：
MICROBIAL PATHOGENESIS
PMID：
36243383
The circ_FAM53B-miR-183-5p-CCDC6 axis modulates the malignant behaviors of papillary thyroid carcinoma cells
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Author：
Zhang Chong, Gu Huxia, Liu Dingrong, Tong Fuyun, Wei Huijie, Zhou Dan, Fang Jing, Dai Xiaolu, Tian Haibo
IF：
3.8420
Publish_to：
MOLECULAR AND CELLULAR BIOCHEMISTRY
PMID：
35598218
E2F2 enhances the chemoresistance of pancreatic cancer to gemcitabine by regulating the cell cycle and upregulating the expression of RRM2
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Author：
Liu Qianfan, Song Chunzhuo, Li Junjun, Liu Meng, FU Liyue, Jiang Jiuliang, Zeng Zhirui, Zhu Haitao
IF：
3.7380
Publish_to：
MEDICAL ONCOLOGY
PMID：
35716217
Engagement of an optimized lentiviral vector enhances the expression and cytotoxicity of CAR in human NK cells
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Author：
Changjiang Guo, Han Chen, Jie Yu, Hui Lu, Qing Xia, Xiaojuan Li, Xiali Guo, Tong Wang, Lingtong Zhi, Zhiyuan Niu, Wuling Zhu
IF：
3.6000
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
36736195
Translocator Protein Regulate Polarization Phenotype Transformation of Microglia after Cerebral Ischemia–reperfusion Injury
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Author：
Shadamu Yusuying, Shalayiding Yusuyin, Xiaojiang Cheng
IF：
3.5900
Publish_to：
NEUROSCIENCE
PMID：
34624453
Bladder cancer tissue-derived exosomes suppress ferroptosis of T24 bladder cancer cells by transporting miR-217
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Author：
Zhong-Ming Huang, Hai Wang, Zhi-Gang Ji
IF：
3.5790
Publish_to：
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
PMID：
36461670
CNR1 may reverse progesterone-resistance of endometrial cancer through the ERK pathway
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Author：
Fei Ding, Chunping Qiu, Wenzhi Li, Zhiming Liu, Deshui Kong, Xiaohong Ma, Jie Jiang
IF：
3.5750
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
33640608
Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway: Tumor-promoting effect of LPCAT1 in endometrial cancer
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Author：
Tianyi Zhao, Rui Sun, Xiaohong Ma, Lina Wei, Yixin Hou, Kun Song, Jie Jiang
IF：
3.5110
Publish_to：
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
PMID：
35880567
circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis
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Author：
Shu Song, Yuhan Shi, Dong Zeng, Jingjing Xu, Yuexiang Yang, Wenjuan Guo, Ye Zheng, Haicheng Tang
IF：
3.5000
Publish_to：
JOURNAL OF GENE MEDICINE
PMID：
36740786
ATF3 Regulates Osteogenic Function by Mediating Osteoblast Ferroptosis in Type 2 Diabetic Osteoporosis
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Author：
Yantao Zhao, Yunxia Du, Yijie Gao, Zhijie Xu, Dexiang Zhao, Maowei Yang
IF：
3.4640
Publish_to：
DISEASE MARKERS
PMID：
36340581
Tenascin C Promotes Glioma Cell Malignant Behavior and Inhibits Chemosensitivity to Paclitaxel via Activation of the PI3K/AKT Signaling Pathway
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Author：
Zhang Qingping, Xu Binchu, Hu Fulan, Chen Xianjin, Liu Xinmin, Zhang Qinghua, Zuo You
IF：
3.4440
Publish_to：
JOURNAL OF MOLECULAR NEUROSCIENCE
PMID：
33876384
LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis
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Author：
Hongdan Dai, Jianming Wang, Zhenglan Huang, Hui Zhang, Xin Wang, Qian Li, Wenli Feng
IF：
3.3990
Publish_to：
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
PMID：
34723728
Transcriptome analysis of long non-coding RNAs reveals NR_015556 lncRNA is a novel regulator for adipocyte differentiation
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Author：
Changqing Zuo, Yaqiong Pan, Dan Leng, Xiuju Chen, Fanghongniu Dong, Zhanying Lin, Zhong Dai, Zonggui Wang
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
35231655
Prefoldin and prefoldin-like complex subunits as predictive biomarkers for hepatocellular carcinoma immunotherapy
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Author：
Haichao Zhao, Changzhou Chen, Chuanli Yang, Shaojian Mo, Haoliang Zhao, Yanzhang Tian
IF：
3.3090
Publish_to：
PATHOLOGY RESEARCH AND PRACTICE
PMID：
35217267
Podocarpusflavone alleviated renal fibrosis in obstructive nephropathy by inhibiting Fyn/Stat3 signaling pathway
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Author：
Zhu Bingwen, Han Rangyue, Ni Yufang, Guo Huaiying, Liu Xiaoheng, Li Jianchun, Wang Li
IF：
3.3000
Publish_to：
Journal of Natural Medicines
PMID：
36884159
Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis
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Author：
Yu Xiuling, Niu Tongtong, Liu Chi
IF：
3.2640
Publish_to：
BMC NEUROSCIENCE
PMID：
36357913
Evaluation of [18F]tetrafluoroborate as a Potential PET Imaging Agent in a Sodium Iodide Symporter-Transfected Cell Line A549 and Endogenous NIS-Expressing Cell Lines MKN45 and K1
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Author：
Mengda Niu, Jingjing Qin, Liang Wang, Yujia He, Chuanhuizi Tian, Yanyan Chen, Pufeng Huang, Zhiping Peng
IF：
3.2500
Publish_to：
Molecular Imaging
PMID：
35330799
Swine NONO is an essential factor to inhibit pseudorabies virus infection
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Author：
Dandan Jiang, Chenlong Jiang, Chao Sui, Xiangju Wu, Yue Hu, Changhee Lee, Xiaoyan Cong, Juntong Li, Yijun Du, Jing Qi
IF：
3.2460
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
36306554
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway
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Author：
Cheng Lan, Wang Huan, Maboh ReneNfornah, Mao Gaowei, Wu Xiaoying, Chen Hui
IF：
3.2160
Publish_to：
Journal of Cardiovascular Translational Research
PMID：
35478454
Glycoproteomic analysis reveals the effects of bisecting GlcNAc in intrahepatic cholangiocarcinoma
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Author：
Dan Wei, Li Cheng, Li Jun, Li Pengfei, Xin Miaomiao, Chen Zexuan, Dang Liuyi, Yu Zihao, Li Jing, Shen Jiechen, Hu Liangshuo, Sun Shisheng
IF：
3.0090
Publish_to：
GLYCOCONJUGATE JOURNAL
PMID：
36322335
Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis
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Author：
Xuemei Huang, Chunfeng Liang, Haiyan Yang, Xin Li, Xiujun Deng, Xinghuan Liang, Li Li, Zhenxing Huang, Decheng Lu, Yan Ma, Zuojie Luo
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
33907586
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro
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Author：
Chen Yisheng, Zhang Jinye, Wei Shuo
IF：
2.8000
Publish_to：
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
PMID：
36503460
Transcriptome analysis in an AEG‑1‑deficient neuronal HT22 cell line
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Author：
Kunmei Liu, Panpan Wan, Yue Huang, Bin Wang, Xuequan Wang, Rui Zhang, Le Guo
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
36237597
Effects of Notch2 on proliferation, apoptosis and steroidogenesis in bovine luteinized granulosa cells
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Author：
Yating Li, Jiongjie Jing, Wenqing Dang, Qi Han, Xiangyu Guo, Kaiqi Jia, Ying Cheng, Kai Wang, Ermias Kebreab, Lihua Lyu
IF：
2.7400
Publish_to：
THERIOGENOLOGY
PMID：
34023619
Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells
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Author：
Zhu Xiang-xing, Pan Jia-sheng, Lin Tao, Yang Ye-cheng, Huang Qiu-yan, Yang Shuai-peng, Qu Zi-xiao, Lin Zi-sheng, Wen Jian-cong, Yan Ai-fen, Feng Juan, Liu Lian, Zhang Xiao-li, Lu Jia-hong, Tang Dong-sheng
IF：
2.7160
Publish_to：
BIOTECHNOLOGY LETTERS
PMID：
34997407
MicroRNA-154-5p suppresses cervical carcinoma growth and metastasis by silencing Cullin2 in vitro and in vivo
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Author：
Yaqin Li， Yimiao Wei， Honglei Zhang， Ying Bai， Xiuting Wang， Qi Li， Yatao Liu， Shuling Wang， Jiapu Wang， Songquan Wen， Jiarong Li， Weihong Zhao
IF：
2.7000
Publish_to：
PeerJ
PMID：
37397007
Nuclear Dbf2-related Kinase 1 functions as tumor suppressor in glioblastoma by phosphorylation of Yes-associated protein
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Author：
Bin Chen, Bin Liu, Tao Yu, Yun-Feng Han, Chao Wu, Zhen-Yu Wang
IF：
2.6280
Publish_to：
CHINESE MEDICAL JOURNAL
PMID：
34343153
Application of the modified cytosine base-editing in the cultured cells of bama minipig
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Author：
Pan Jia-sheng, Lin Zi-sheng, Wen Jian-cong, Guo Jian-feng, Wu Xia-hui, Liu Ying-ying, Lai Wen-jun, Liang Qi-ying, Xie Yong-shi, Chen Yi-rou, Chen Yi-hong, Yan Ai-fen, Feng Juan, Liu Lian, Gong Dao-yuan, Zhu Xiang-xing, Lu Jia-hong, Tang Dong-sheng
IF：
2.4610
Publish_to：
BIOTECHNOLOGY LETTERS
PMID：
34189671
Overexpression of ING3 is associated with attenuation of migration and invasion in breast cancer
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Author：
Huimeng Li, Hengyu Zhang, Xin Tan, Dequan Liu, Rong Guo, Maohua Wang, Yiyin Tang, Kai Zheng, Wenlin Chen, Hongwan Li, Mingjian Tan, Ke Wang, Rui Liu, Shicong Tang
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
34007308
Porcine epidemic diarrhea virus (PEDV) ORF3 protein inhibits cellular type I interferon signaling through down-regulating proteins expression in RLRs-mediated pathway
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Author：
Liang Zheng, Hongxian Liu, Zhipiao Tian, Matthew Kay, Hongyu Wang, Lixin Cheng, Wenlong Xia, Jiankang Zhang, Wenling Wang, Hongwei Cao, Xiaojuan Xu, Zhenqiu Gao, Rongqing Geng, Zhijun Wu, Hua Zhang
IF：
2.4000
Publish_to：
RESEARCH IN VETERINARY SCIENCE
PMID：
37148734
Rapid, sensitive and cost-effective determination of immune checkpoint inhibitor activity using a magnetic bead-based binding assay
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Author：
Qinglai Meng, Yujia Fu, Shenzhi Li, Yujuan Yan, Danli Duan, Donald D. Anthony, Yueping Zhu, Xuehua Wu, Feng Qian, Changxin Wu
IF：
2.3030
Publish_to：
JOURNAL OF IMMUNOLOGICAL METHODS
PMID：
34464606
Mef2a is a positive regulator of Col10a1 gene expression during chondrocyte maturation
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Author：
Chen Chen， Xuan Wu， Tiaotiao Han， Jinnan Chen， Huiqin Bian， Ruoxuan Hei， Sitao Tang， Zhenying Li， Yaojuan Lu， Junxia Gu， Longwei Qiao， Qiping Zheng
IF：
2.2000
Publish_to：
American Journal of Translational Research
PMID：
37434855
The role of CSE1L silencing in the regulation of proliferation and apoptosis via the AMPK/mTOR signaling pathway in chronic myeloid leukemia
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Author：
Xiao-Yu Liu, Yong-Hong Wang, Jing Wang, Ji-Kun Quan, Xu-Dong Li, Kun-Ping Guan
IF：
1.9000
Publish_to：
Hematology
PMID：
36652402
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