英文名称 |
Anti-ICOS Polyclonal Antibody |
中文名称 |
诱导协同刺激分子CD278抗体 |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
稀释比例 |
IHC 1:10-100. |
靶标 |
ICOS |
别名 |
Activation inducible lymphocyte immunomediatory molecule, Activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278, CD278 antigen, CVID1, ICOS, ICOS_HUMAN, Inducible costimulator, Inducible T cell co stimulator, Inducible T-cell costimulator, MGC39850 |
背景说明 |
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. |
Swiss Prot |
Q9Y6W8 |
Gene ID |
29851 |
亚细胞定位 |
Cell membrane Cytoplasm |
免疫原 |
Recombinant protein of human ICOS |
理论分子量 |
23kDa |
纯化方法 |
Affinity purification |
储存液 |
pH7.4 PBS,0.05% NaN3,40% Glycerol. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
50ul 100ul |
交叉反应 |
Human |
应用 |
IHC |
研究领域 |
免疫学 |
单位 |
支 |
属性分类 |
其他抗体 |