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2，3，5氯化三苯基四氮唑 TTC
英文名称:TTC 2，3，5-Triphenyl-2H-Tetrazolium Chloride
CAS:No.298-96-4
分子式:C19H15ClN4
分子量:334.81
储存条件:2-8℃保存，有效期3年。
产品简介
| 中文名称 | 2，3，5氯化三苯基四氮唑 TTC |
| 英文名称 | TTC 2，3，5-Triphenyl-2H-Tetrazolium Chloride |
| 别名 | 2,3,5-三苯基氯化四氮唑;四氮唑红;红四唑 |
| CAS | No.298-96-4 |
| 分子式 | C19H15ClN4 |
| 分子量 | 334.81 |
| 纯度/级别 | Purity≥98.0%/Reagent Grade |
| 外观(性状) | 白色至浅黄色粉末 |
| 溶解性 | 0.4% 用Pb溶解，2% 用Pb溶解 |
| 储存条件 | 2-8℃保存，有效期3年。 |
| 规格 | 1g 5g 25g |
| 单位 | 瓶 |
2,3,5-氯化三苯基四氮唑，又称四唑红，简称TTC，TTZ，或TPTZ，一种脂溶性光敏感复合物，即可用来检测种子的生存能力，也可用来检测哺乳动物组织的缺血梗塞。检测机制在于TTC本身可作为一种氧化还原指示剂，活细胞内的脱氢酶（尤其是线粒体内的琥珀酸脱氢酶）可以将TTC还原为红色甲臢化合物TPF（1,3,5-triphenylformazan）。对于种子或者植物组织来说，染色结果为活组织被染成不同程度的红色，死组织或者无生命力的组织不着色。对于缺血梗塞组织，因组织坏死脱氢酶活力丧失呈现苍白色，而正常组织呈深红色。TTC常用的染色浓度为2%（w/v）(货号：G3005)，也可根据组织类型做浓度的适当调整。
染色方法
1.1染色工作液的配制（动物组织，仅供参考）
TTC通常用PB磷酸缓冲盐溶液来配制，pH范围为6.5-7.5之间，常用的工作浓度为2%，也可用1%或者更低的浓度，根据自身实验体系调整。
可使用以下的缓冲盐体系配制：
1）取9.078g KH2PO4（Mw：136.09）溶于1L去离子水内，制备成66.7mM KH2PO4储存液；取10.9472g Na2HPO4·H2O（Mw：159.974）溶于1L去离子水内，制备成68.6mM Na2HPO4储存液；将两份KH2PO4储存液与1份Na2HPO4储存液充分混合，即得到需要的PB磷酸缓冲液溶液。
2）根据需要的TTC工作液浓度来制备，如加入2g TTC粉末到100ml混合的PB磷酸盐缓冲液中，即得到2%的染色工作液。此时的溶液pH值在6.5-7.5之间。此工作液可装到不透明的白色瓶或者棕色瓶子内，4℃保存几个月稳定。
【注意：TTC染色液的缓冲体系可根据自己的实验习惯来调整；也可用去离子水来溶解配置成10mg/ml的储存液，过滤除菌，建议此法染色液当天使用。】
1.2 染色方法（动物组织）
1）取新鲜组织切片放到装有TTC染色液的染色容器内，37℃避光孵育15-30min，边孵育边观察颜色变化；【注意：TTC染色液可重复使用2-3次，可将用过的TTC染色液放到新的容器内继续使用。】
2）【可选】轻柔的吸取缓冲液（如1×PBS）将组织表面多余的染色液冲洗掉；
3）此时即可观察或者拍照。若需长久保存，用4%多聚甲醛溶液（货号：P1110）固定10-20min。
注意事项
1）本品具有微量的光和热敏感性，使用以及存放的过程中避免长时间曝光或者接触到过高温度下。
2）为了您的安全和健康，请穿实验服并戴一次性手套操作。
3) 本品不适合用PBS溶解。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
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5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
38042386
Ligustilide attenuates ischemic stroke injury by promoting Drp1-mediated mitochondrial fission via activation of AMPK
点击查看 >>
Author：
Qian Wu, Jiao Liu, Zhiguo Mao, Liyu Tian, Ning Wang, Guangyun Wang, Yang Wang, Saiwang Seto
IF：
5.3400
Publish_to：
PHYTOMEDICINE
PMID：
34929562
Exercise pretreatment alleviates neuroinflammation and oxidative stress by TFEB-mediated autophagic flux in mice with ischemic stroke
点击查看 >>
Author：
Yun Zhao, Zhongqiu Hong, Yao Lin, Weimin Shen, Yuhan Yang, Zejie Zuo, Xiquan Hu
IF：
5.3000
Publish_to：
EXPERIMENTAL NEUROLOGY
PMID：
36914085
Engeletin alleviates cerebral ischemia reperfusion-induced neuroinflammation via the HMGB1/TLR4/NF-κB network
点击查看 >>
Author：
Yangyang Xu, Jie Zhang, Fei Gao, Wenna Cheng, Ye Zhang, Chuanmei Wei, Shuping Zhang, Xinfu Gao
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
37132060
Zhachong Shisanwei Pill resists ischemic stroke by lysosome pathway based on proteomics and bioinformatics
点击查看 >>
Author：
Qi Song, Lei Bi, Jiakang Jiao, Jinfeng Shang, Qiannan Li, Lizha Shabuerjiang, Meirong Bai, Xin Liu
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
36183948
Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis
点击查看 >>
Author：
Ming Li, Zhaoli Meng, Shichao Yu, Jiarui Li, Yupeng Wang, Wei Yang, Hui Wu
IF：
5.1680
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
36055377
Inhalation of Atmospheric-Pressure Gas Plasma Attenuates Brain Infarction in Rats With Experimental Ischemic Stroke
点击查看 >>
Author：
Ye Chen, Bingyan Yang, Lixin Xu, Zhongfang Shi, Ruoyu Han, Fang Yuan, Jiting Ouyang, Xu Yan, Kostya Ken Ostrikov
IF：
5.1520
Publish_to：
Frontiers in Neuroscience
PMID：
35516812
SLC15A3 is transcriptionally regulated by HIF1α and p65 to worsen neuroinflammation in experimental ischemic stroke
点击查看 >>
Author：
Yu Shan, Yang Jinghui, Zhang Rui, Guo Qian, Wang Lu
IF：
5.1000
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
38717559
AM1241 alleviates myocardial ischemia-reperfusion injury in rats by enhancing Pink1/Parkin-mediated autophagy
点击查看 >>
Author：
Wenhua Liu, Changgong Chen, Xingjian Gu, Li Zhang, Xiang Mao, Zili Chen, Luyuan Tao
IF：
5.0370
Publish_to：
LIFE SCIENCES
PMID：
33607150
Neuroprotective Effects of Activin A against Cerebral Ischemia/Reperfusion Injury in Mice by Enhancing Nrf2 Expression to Attenuate Neuronal Ferroptosis
点击查看 >>
Author：
Fengzhi Wang, Ming Ma, Jiahui Yang, Xiaohua Shi, Jiaoqi Wang, Zhongxin Xu
IF：
5.0000
Publish_to：
ACS Chemical Neuroscience
PMID：
37473431
The Wound-Healing Effect of Mango Peel Extract on Incision Wounds in a Murine Model
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Author：
Lesslie Espinosa-Espinosa, Leticia Garduño-Siciliano, Mario Rodriguez-Canales, Luis Barbo Hernandez-Portilla, Maria Margarita Canales-Martinez, Marco Aurelio Rodriguez-Monroy
IF：
4.9270
Publish_to：
MOLECULES
PMID：
35011491
Integrated serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of yiqitongmai decoction (YQTMD) against myocardial infarction
点击查看 >>
Author：
Hao Yu, Ning Wang, Xuerong Zhao, Lan Han, Jinyong Peng
IF：
4.8000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
38750989
Experimental verification and validation of immune biomarkers based on chromatin regulators in ischemic stroke
点击查看 >>
Author：
Beibei Yu, Yunze Tian, Yongfeng Zhang, Boqiang Lv, Jianzhong Li, Shouping Gong
IF：
4.7720
Publish_to：
Frontiers in Genetics
PMID：
36105086
Lactate Contributes to Remote Ischemic Preconditioning–Mediated Protection Against Myocardial Ischemia Reperfusion Injury by Facilitating Autophagy via the AMPK–Mammalian Target of Rapamycin–Transcription Factor EB–Connexin 43 Axis
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Author：
Zhang-Jian Yang, Wei-Fang Zhang, Qing-Qing Jin, Zhi-Rong Wu, Yun-Yan Du, Hao Shi, Zhen-Sheng Qu, Xiao-Jian Han, Li-Ping Jiang
IF：
4.7000
Publish_to：
AMERICAN JOURNAL OF PATHOLOGY
PMID：
39069170
Chlorogenic acid protects against myocardial ischemia每reperfusion injury in mice by inhibiting Lnc Neat1/NLRP3 inflammasome-mediated pyroptosis
点击查看 >>
Author：
Chai Xin, Liang Zhengwei, Zhang Junshi, Ding Jing, Zhang Qian, Lv Sha, Deng Yazhu, Zhang Rongrui, Lu Deqin
IF：
4.6000
Publish_to：
Scientific Reports
PMID：
37853132
Cytological and Molecular Mechanism of Low Pollen Grain Viability in a Germplasm Line of Double Lotus
点击查看 >>
Author：
Guangyang Liu, Fengjun Liu, Huiyan Jiang, Jun Li, Jing Jing, Qijiang Jin, Yanjie Wang, Ping Qian, Yingchun Xu
IF：
4.5000
Publish_to：
Plants-Basel
PMID：
36679100
TRPC6 regulates necroptosis in myocardial ischemia/reperfusion injury via Ca2+/CaMKII signaling pathway
点击查看 >>
Author：
Junhao Li, Jiaji Zhang, Yunlong Zhong, Dongge Xie, Han Han, Zhongqing Zhang, Yong Liu, Shoutian Li
IF：
4.4000
Publish_to：
CELLULAR SIGNALLING
PMID：
39134250
Validation of efficacy and mechanism of Sanwei-Tanxiang powder in improving myocardial ischemia reperfusion injuries
点击查看 >>
Author：
Sun Yu-Hui, Bu Ren, Wang Yue-Wu, Hu Yu-Chong, Wang Xu-Mei, Dong Xin, Zu Wen, Niu Yan, Zhao Peng-Wei, Sun Peng, Ru Shi-Hang, Lu Jing-Kun, Na Sheng-Sang
IF：
4.3800
Publish_to：
Scientific Reports
PMID：
33437022
Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling
点击查看 >>
Author：
Liming Yu, Bing Gong, Weixun Duan, Chongxi Fan, Ji
IF：
4.2590
Publish_to：
Scientific Reports 7, Article number: 41337 (2017)
PMID：
28120943
EGCG protects against myocardial I/RI by regulating lncRNA Gm4419-mediated epigenetic silencing of the DUSP5/ERK1/2 axis
点击查看 >>
Author：
Min Zeng, Xin Wei, Yang-Li He, Ji-Xiong Chen, Wen-Ting Lin, Wen-Xing Xu
IF：
4.2190
Publish_to：
TOXICOLOGY AND APPLIED PHARMACOLOGY
PMID：
34740634
Resveratrol protects cardiomyocytes against ischemia/reperfusion-induced ferroptosis via inhibition of the VDAC1/GPX4 pathway
点击查看 >>
Author：
Tie Hu, Hua-Xi Zou, Ze-Yu Zhang, Yi-Cheng Wang, Fa-Jia Hu, Wen-Xiong Huang, Ji-Chun Liu, Song-Qing Lai, Huang Huang
IF：
4.2000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38561102
Downregulation of lncRNA SNHG14 alleviates neurons injury by modulating the miR-181c-5p/BMF axis in ischemic stroke
点击查看 >>
Author：
Xiancong Bu, Yuhua Zhao, Meizhi Chang, Xuchun Ge
IF：
4.0790
Publish_to：
BRAIN RESEARCH BULLETIN
PMID：
34224818
Ameliorative Role of Mitochondrial Therapy in Cognitive Function of Vascular Dementia Mice
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Author：
Wu Deng-Pan, Wei Yan-Su, Du Yu-Xuan, Liu Ling-Ling, Yan Qiu-Qing, Zhao Yuan-Dan, Yu Chao, Liu Jin-Yuan, Zhong Zhen-Guo, Huang Jin-Lan
IF：
4.0000
Publish_to：
JOURNAL OF ALZHEIMERS DISEASE
PMID：
38250768
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats
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Author：
Ren Yikun, Jiang Jin, Jiang Wenxia, Zhou Xueling, Lu Wenhao, Wang Jingwen, Luo Yong
IF：
3.9960
Publish_to：
NEUROCHEMICAL RESEARCH
PMID：
34075523
Tongmai Yangxin pill alleviates myocardial no-reflow by activating GPER to regulate HIF-1α signaling and downstream potassium channels
点击查看 >>
Author：
Ting Chen, Yulong Zhang, Manyun Chen, Pu Yang, Yi Wang, Wei Zhang, Weihua Huang, Wei Zhang
IF：
3.8000
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
36896463
PCSK9 inhibition protects against myocardial ischemia-reperfusion injury via suppressing autophagy
点击查看 >>
Author：
Guangwei Huang, Xiyang Lu, Haiyan Zhou, Runhong Li, Qing Huang, Xinlin Xiong, Zhenhua Luo, Wei Li
IF：
3.7500
Publish_to：
MICROVASCULAR RESEARCH
PMID：
35460665
Colchicine-Containing Nanoparticles Attenuates Acute Myocardial Infarction Injury by Inhibiting Inflammation
点击查看 >>
Author：
Wang Li, Peng Yunfan, Song Lijun, Xia Dasheng, Li Chao, Li Zhuqing, Li Qi, Yu Ao, Lu Chengzhi, Wang Yongjian
IF：
3.7270
Publish_to：
CARDIOVASCULAR DRUGS AND THERAPY
PMID：
34436706
Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis
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Author：
Jie Zhao, Yue Wu, Shanshan Liang, Xiangyu Piao
IF：
3.7080
Publish_to：
NEUROSCIENCE
PMID：
35090880
Irisin ameliorates myocardial ischemia-reperfusion injury by modulating gut microbiota and intestinal permeability in rats
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Author：
Qingqing Liu, Yu Zhu, Guangyao Li, Tiantian Guo, Mengtong Jin, Duan Xi, Shuai Wang, Xuezhi Liu, Shuming Guo, Hui Liu, Jiamao Fan, Ronghua Liu
IF：
3.7000
Publish_to：
PLoS One
PMID：
37656700
CircZfp609 contributes to cerebral infarction via sponging miR-145a-5p to regulate BACH1
点击查看 >>
Author：
Zhou Ziying, Wang Xijia, Hu Qian, Yang Zhigang
IF：
3.6000
Publish_to：
METABOLIC BRAIN DISEASE
PMID：
37097437
Translocator Protein Regulate Polarization Phenotype Transformation of Microglia after Cerebral Ischemia–reperfusion Injury
点击查看 >>
Author：
Shadamu Yusuying, Shalayiding Yusuyin, Xiaojiang Cheng
IF：
3.5900
Publish_to：
NEUROSCIENCE
PMID：
34624453
Long non-coding RNA Gm11974 aggravates oxygen–glucose deprivation-induced injury via miR-122-5p/SEMA3A axis in ischaemic stroke
点击查看 >>
Author：
Yang Ling, Wang Lijuan, Wang Juan, Liu Ping
IF：
3.5840
Publish_to：
METABOLIC BRAIN DISEASE
PMID：
34338972
TRIM27 protects against cardiac ischemia-reperfusion injury by suppression of apoptosis and inflammation via negatively regulating p53
点击查看 >>
Author：
Yan Li, Qing Meng, Ling Wang, Yongjian Cui
IF：
3.5750
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
33865220
Uric acid inhibits HMGB1-TLR4-NF-kB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia
点击查看 >>
Author：
王强/程继东
IF：
3.5700
Publish_to：
Biochemical and Biophysical Research Communications
PMID：
33429196
Multiwall carbon nanotubes/polycaprolactone composites for bone tissue engineering application
点击查看 >>
Author：
Lanlan Pan,Xibo Pei,Rui He,Qianbing Wan,Jian Wang
IF：
3.5540
Publish_to：
Colloids and Surfaces B: Biointerfaces
PMID：
22305638
Resveratrol Inhibits Activation of Microglia after Stroke through Triggering Translocation of Smo to Primary Cilia
点击查看 >>
Author：
Hongyan Liao, Jiagui Huang, Jie Liu, Yue Chen, Huimin Zhu, Xuemei Li, Jun Wen, Qin Xiang, Qin Yang
IF：
3.5080
Publish_to：
Journal of Personalized Medicine
PMID：
36836502
RNA-seq based transcriptomic map reveals multiple pathways of necroptosis in treating myocardial ischemia reperfusion injury
点击查看 >>
Author：
Yijia Zhang, Qingbiao Song, Sihan E, Xuehao Guan, Zhiyu Zhang, Zhaodong Juan, Xiaotong Sun, Yingxia Liang
IF：
3.5000
Publish_to：
GENE
PMID：
38341002
High‑fat diet‑induced LCN2 exacerbates myocardial ischemia‑reperfusion injury by enhancing platelet activation
点击查看 >>
Author：
Peng Li, Juhai Chen, Mingdong Wang, Qi Wang, Xingde Liu
IF：
3.4000
Publish_to：
Molecular Medicine Reports
PMID：
39301623
A New Target of Electroacupuncture Pretreatment Mediated Sympathetic Nervous to Improve MIRI: Glutamatergic Neurons in Fastigial Nucleus of the Cerebellum
点击查看 >>
Author：
Xiang Zhou, Jie Zhou, Fan Zhang, Qi Shu, Qian-yi Wang, Yan Wu, Hui-min Chang, Bin Zhang, Qing Yu, Rong-lin Cai
IF：
3.3000
Publish_to：
NEUROSCIENCE
PMID：
37923164
Long non-coding RNA AK006774 inhibits cardiac ischemia-reperfusion injury via sponging miR-448
点击查看 >>
Author：
Shen Nie, Xiaoya Cui, Jinping Guo, Xiaohua Ma, Haijun Zhi, Shilei Li, Yong Li
IF：
3.2690
Publish_to：
Bioengineered
PMID：
34369259
Effects of lysophosphatidic acid receptor 5 on NLRC4 inflammasome in brain tissues of transient cerebral ischemia/reperfusion rat.
点击查看 >>
Author：
Zhang X, Huang T, Lang L, Yu L
IF：
3.2470
Publish_to：
HUMAN & EXPERIMENTAL TOXICOLOGY
PMID：
35230166
Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress
点击查看 >>
Author：
Guo-long Zhao1, Li-ming Yu2, Wen-li Gao1, Wei-xun
IF：
3.2230
Publish_to：
Acta Pharmacologica Sinica (2016) 37: 354-367
PMID：
26806299
CD137 Signal Mediates Cardiac Ischemia–Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes
点击查看 >>
Author：
Xu Yao, Chen Rui, Yan Jinchuan, Zang Guangyao, Shao Chen, Wang Zhongqun
IF：
3.2160
Publish_to：
Journal of Cardiovascular Translational Research
PMID：
35419772
Connexin43 overexpression promoted ferroptosis and increased myocardial vulnerability to ischemia-reperfusion injury in type 1 diabetic mice
点击查看 >>
Author：
Yuhui Yang, Jiajia Chen, Jiaqi Zhou, Dongcheng Zhou, Anyuan Zhang, Yuxin Jiang, Jiefu Lin, Weiyi Xia, Yin Cai, Ronghui Han, Yan Lu, Danyong Liu, Zhengyuan Xia
IF：
3.2000
Publish_to：
International Journal of Medical Sciences
PMID：
39310260
NLRP3 inflammasome inhibitor MCC950 reduces cerebral ischemia/reperfusion induced neuronal ferroptosis
点击查看 >>
Author：
Xiang Wu, Bo Wang, Yunfei Zhou, Zhongbo Yang, Liangchao Jiang, Zhiyan Kou, Jiaxi Li, Xudong Ma, Jinning Song
IF：
3.1970
Publish_to：
NEUROSCIENCE LETTERS
PMID：
36581063
Chrysophanol accelerates astrocytic mitochondria transfer to neurons and attenuates the cerebral ischemia-reperfusion injury in rats
点击查看 >>
Author：
Xiao-mei Su, Dan-shen Zhang, Nan Zhang
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
38408414
The protective effect of low-dose nicotine on ischemia stroke by maintaining the integrity of the blood-brain barrier
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Author：
Pang Qianqian, Yan Xinyang, Chen Zheng, Yun Liang, Qian Jiang, Dong Zeyi, Wang Miao, Deng Wei, Fu Yao, Hai Tao, Chen Zhichao, Rong Xianfang
IF：
3.0000
Publish_to：
NICOTINE & TOBACCO RESEARCH
PMID：
39921606
XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells
点击查看 >>
Author：
Xue Teng Xiao Fan Fan Qi Li Shuang Liu Dong Yuan W
IF：
2.9760
Publish_to：
Oncology Reports Pages: 1875-1882
PMID：
30628719
HSPB1 overexpression improves hypoxic-ischemic brain damage by attenuating ferroptosis in rats through promoting G6PD expression
点击查看 >>
Author：
Yi Dai, Lan Hu
IF：
2.9740
Publish_to：
JOURNAL OF NEUROPHYSIOLOGY
PMID：
36321738
Guanxin V Relieves Ventricular Remodeling by Inhibiting Inflammation: Implication from Virtual Screening, Systematic Pharmacology, Molecular Docking, and Experimental Validation
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Author：
Liang Bo, Zhang Xiao-xiao, Gu Ning
IF：
2.9000
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
37528325
Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats
点击查看 >>
Author：
Li Lu, Pan Guanghua, Fan Rong, Li Dalei, Guo Lei, Ma Lili, Liang Hui, Qiu Jiaoxue
IF：
2.8380
Publish_to：
BMC Complementary Medicine and Therapies
PMID：
35778706
Intramyocardial delivery of injectable hydrogel with arctigenin alleviated myocardial ischemia–reperfusion injury in rats
点击查看 >>
Author：
Chengyin Liu, Xuejun Jiang, Lanyu Liang, Han Liu, Li Li, Qing Shan
IF：
2.8000
Publish_to：
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
PMID：
38246885
PCSK9 Knockdown Can Improve Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy
点击查看 >>
Author：
Huang Guangwei, Lu Xiyang, Duan Zonggang, Zhang Kai, Xu Lei, Bao Hailong, Xiong Xinlin, Lin Muzhi, Li Chao, Li Yunquan, Zhou Haiyan, Luo Zhenhua, Li Wei
IF：
2.7550
Publish_to：
Cardiovascular Toxicology
PMID：
36342620
DUSP10 alleviates ischemic stroke-induced neuronal damage by restricting p38/JNK pathway
点击查看 >>
Author：
Ni-Na Song, Ying Zhao, Chuang Sun, Jun Zhang, Guang-Jun Lin, Xiao-Wei Yin, Chun-Ye Ma
IF：
2.7000
Publish_to：
BEHAVIOURAL BRAIN RESEARCH
PMID：
37164190
Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra
点击查看 >>
Author：
Deng Yihao, Guo Tao, Wu Zhiyuan, Zhao Xiaoming, Dong Lingling, He Hongyun
IF：
2.6990
Publish_to：
Iranian Journal of Basic Medical Sciences
PMID：
34804431
Nicorandil inhibits TLR4/MyD88/NF-κB/NLRP3 signaling pathway to reduce pyroptosis in rats with myocardial infarction
点击查看 >>
Author：
Feng Chen, Zhi-Qing Chen, Gui-Ling Zhong, Ji-Jin Zhu
IF：
2.6910
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
PMID：
34034564
Exosomes Released from Bone-Marrow Stem Cells Ameliorate Hippocampal Neuronal Injury Through transferring miR-455-3p
点击查看 >>
Author：
Chao Gan, Feng Ouyang
IF：
2.6770
Publish_to：
Journal of Stroke & Cerebrovascular Diseases
PMID：
35598413
Integrated Bioinformatics Analysis and Verification of Gene Targets for Myocardial Ischemia-Reperfusion Injury
点击查看 >>
Author：
Jianru Wang, Xiaohui Li, Guangcao Peng, Genhao Fan, Mengmeng Zhang, Jian Chen
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
35463067
Saposhnikoviae Radix Enhanced the Angiogenic and Anti-Inflammatory Effects of Huangqi Chifeng Tang in a Rat Model of Cerebral Infarction
点击查看 >>
Author：
Qiu-Yue Wang, Na Zhang, Shu-Yu Liu, Xi-Hong Jiang, Shu-Min Liu
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
34594389
Yixin Ningshen Tablet Alleviates Comorbidity of Myocardial Infarction and Depression by Enhancing Myocardial Energy Metabolism and Increasing Availability of Monoamine Neurotransmitter
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Author：
Jiang Bing, Wu Ruo-ming, Li Hai-dong, Li Kun, Li Hui, Dang Wen-zhen, Feng Gui-ze, Bao Wei-lian, Ye Guan, Shen Xiao-yan
IF：
2.6260
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
35319073
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation
点击查看 >>
Author：
Cuijie Lu, Ling Liu, Shuai Chen, Junfei Niu, Sheng Li, Wenxian Xie, Xiang Cheng
IF：
2.5570
Publish_to：
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
PMID：
34370882
Mechanism of scutellarin inhibition of astrocyte activation to type A1 after ischemic stroke
点击查看 >>
Author：
Yongwei Zou, Jingchun Pei, Cheng Wan, Shuangshuang Liu, Bin Hu, Zhigao Li, Zhiwei Tang
IF：
2.5000
Publish_to：
Journal of Stroke & Cerebrovascular Diseases
PMID：
38219378
Protective effects of oridonin against cerebral ischemia/reperfusion injury by inhibiting the NLRP3 inflammasome activation
点击查看 >>
Author：
Yujie Jia, Yu Tong, Lianqiu Min, Yanrong Li, Yan Cheng
IF：
2.4660
Publish_to：
TISSUE & CELL
PMID：
33676236
ΜicroRNA‑122 protects against ischemic stroke by targeting Maf1
点击查看 >>
Author：
Mengmeng Wang, Xiaoman Liu, Yu Wu, Yi Wang, Jiahui Cui, Jing Sun, Ying Bai, Ming-Fei Lang
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
33936273
Physical Characterization, Nutrient, Phenolic Profiles and Antioxidant Activities of 16 litchi Cultivars Grown in the Upper Yangtze River Region
点击查看 >>
Author：
Si Tan, Hongna Zhang, Qin Chen, Yuxin Tang, Jiaqi Yang, Xin Zhang, Wenfeng Li, Shengyou Shi
IF：
2.4080
Publish_to：
CHEMISTRY & BIODIVERSITY
PMID：
34797035
Eriocalyxin B alleviated ischemic cerebral injury via limiting microglia-mediated excessive neuroinflammation in mice
点击查看 >>
Author：
Yanqiang CHEN, Cong ZHANG, Liming ZHAO, Rong CHEN, Peipei ZHANG, Junxia LI, Xueping ZHANG, Xiangjian ZHANG
IF：
2.4000
Publish_to：
EXPERIMENTAL ANIMALS
PMID：
37839867
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting NOH-1
点击查看 >>
Author：
Lili TAN, Limin LIU, Jian YAO, Chenghao PIAO
IF：
2.3190
Publish_to：
EXPERIMENTAL ANIMALS
PMID：
33658472
Dexmedetomidine pretreatment alleviates brain injury in middle cerebral artery occlusion (MCAO) model rats by activating PI3K/AKT/NF-κB signaling pathway
点击查看 >>
Author：
Wei Gao, Xue Lv, Hao Li, Xu-Sheng Yan, Dong-Sheng Huo, Zhan-Jun Yang, Zhi-Guo Zhang, Jian-Xin Jia
IF：
2.3000
Publish_to：
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
PMID：
39995113
The promotion of sestrin2/AMPK signaling by HIF-1α overexpression enhances the damage caused by acute myocardial infarction
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Author：
Wang Jie, Du Honglei, Sun Qing, Wan Weiping, Zhang Haifeng
IF：
2.1000
Publish_to：
BMC Cardiovascular Disorders
PMID：
37986153
Amifostine ameliorates cerebral ischaemia-reperfusion injury
via p38-mediated oxidative stress and mitochondrial dysfunction
点击查看 >>
Author：
Huifeng Cheng, Miaojun Lv, Rulin Mi, Guofang Xue
IF：
2.0380
Publish_to：
FOLIA NEUROPATHOLOGICA
PMID：
33480238
Blockage of p38MAPK in astrocytes alleviates brain damage in a mouse model of embolic stroke through the CX43/AQP4 axis
点击查看 >>
Author：
Weiping Chen, Zhiping Wu, Min Yin, Yangbo Zhang, Yiren Qin, Xu Liu, Jianglong Tu
IF：
2.0000
Publish_to：
Journal of Stroke & Cerebrovascular Diseases
PMID：
39393507
The influence of electronic acupuncture at a specific frequency in facilitating the passage of NGF through the blood-brain barrier and its effect on learning and memory in MCAO/R rats
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Author：
Yibin Zhao, Xuqing Mao, Hao Wang, Lin Gan, Shanshan Zhang, Peng Gong, Xianming Lin
IF：
1.6640
Publish_to：
Journal of Integrative Neuroscience
PMID：
35633160
Electroacupuncture regulates FTO/Nrf2/NLRP3 axis-mediated pyroptosis in cerebral ischemia–reperfusion injury
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Author：
Li Chenglong, Ji Haisheng, Mao Wei, Zhang Lida, Tong Tingting, Wang Junli, Cai Liyuan, Wang Hai, Sun Tingting, Yi Hu, Li Shijun, Tu Ying, Zhang Junyu, Wang Haitao, Wu Haiyang, Han Wei, Wang Ying
IF：
1.6000
Publish_to：
NEUROREPORT
PMID：
39976072
Protective effects of puerarin combined with bone marrow mesenchymal stem cells on nerve injury in rats with ischemic stroke
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Author：
Jiane Chen, Xiaoli Wu, Dongliang Nie, Zhimin Yu
IF：
1.5000
Publish_to：
BRAIN INJURY
PMID：
39607797
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2023-10-26 13:51:29