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硫酸卡那霉素
CAS:No.25389-94-0
英文名称:Kanamycin Sulfate
分子式:C18H36N4O11·H2SO4
分子量:582.58
储存条件:Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
纯度:≥98%
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产品简介
| CAS | No.25389-94-0 |
| 中文名称 | 硫酸卡那霉素 |
| 英文名称 | Kanamycin Sulfate |
| 别名 | 硫酸卡那霉素;硫酸单卡那霉素;单硫酸卡那霉素;卡那霉素;卡那辛;;kanamycin monosulfate |
| 分子式 | C18H36N4O11·H2SO4 |
| 分子量 | 582.58 |
| 溶解性 | Soluble in Water ≥100mg/mL |
| 纯度 | ≥98% |
| 外观(性状) | White to off-white Solid |
| 储存条件 | Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 246-933-9 |
| MDL | MFCD00070253 |
| SMILES | OS(O)(=O)=O.O[C@H]1[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@H](CN)[C@@H](O)[C@@H]1O |
| InChIKey | OOYGSFOGFJDDHP-KMCOLRRFSA-N |
| InChI | InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1 |
| PubChem CID | 441374 |
| 靶点 | Bacterial |
| 通路 | Anti-infection |
| 背景说明 | 硫酸卡那霉素为氨基糖甙类广谱抗生素,抗菌谱和新霉素相似,主要与细菌核糖体30S亚单位结合,抑制细菌蛋白质合成。 |
| 生物活性 | Kanamycin sulfate是氨基糖苷类杀菌抗生素，其通过与细菌30S核糖体结合起作用。[1-4] |
| In Vitro | 浓度高于0.0025％的硫酸卡那霉素对双歧双歧杆菌的生长具有显著的抑制作用，并且在孵育12小时或24小时时对其他四种益生菌没有影响。对于B.bifidum的选择性计数，MRS培养基中硫酸卡那霉素的最佳选择浓度为0.005％[3]。 |
| In Vivo | 由卡那霉素(500mg/kg /天)引起的DCN的神经元损伤是可逆的，并且通过JNK1介导的大鼠Bcl-2途径的磷酸化，在DCN上卡那霉素的神经毒性过程中自噬被上调。在卡那霉素给药期后第1天血清BUN和Cr水平均升高。与对照组相比，在卡那霉素给药后第1，7和14天，表达LC3的神经元增加。卡那霉素治疗以时间依赖的方式导致自噬增加[1]。硫酸卡那霉素(5 mg/kg)和氨苄西林钠(10 mg/kg)分别肌肉注射(im)，然后一起给予5匹小马，并且在发炎的滑液中氨苄青霉素浓度超过5 mg/mL约2.5 h注射后，硫酸卡那霉素浓度超过2 mg/mL，在小马中持续7 h [2]。 |
| 动物实验 | 六十六只雄性Sprague-Dawley大鼠(初始体重125-150g，5-6周龄)可自由饮水和定期饮食，并且在第一次治疗前允许1周适应。将动物随机分成一个对照组和七个实验组。对照组大鼠(n = 10)皮下注射等体积的载体(0.9％盐水)10天，与卡那霉素处理组相同，但不含卡那霉素。实验组(每组n = 56，8：分别给予卡那霉素后1，7，14，28，56，70和140天)通过皮下注射接受500mg硫酸卡那霉素/ kg /天，持续10天。每天监测动物体重，并相应地调整卡那霉素的注射剂量。听觉阈值由ABR测试。每只动物进行两次试验，首先在给药开始之前，然后在卡那霉素处理后的不同观察时间点进行。 ABR测量的细节在别处描述。 |
| 数据来源文献 |
[1]. Fan GR， et al. Reversible neurotoxicity of kanamycin on dorsal cochlear nucleus. Brain Res. 2013 Jan 17. pii: S0006-8993(13)00068-1. [2]. Mohamed el SW， et al. Tongue actinomycetoma due to Actinomadura madurae: a rare clinical presentation. J Oral Maxillofac Surg. 2012 Nov;70(11):e622-4. [3]. Guo WS， et al. Effect of Kanamycin Sulfate and Gentamicin on Growth of Probiotics. Advanced Materials Research，2011， 366， 490-493. [4]. Firth EC， et al. Effect of induced synovial inflammation on pharmacokinetics and synovial concentration of sodium ampicillin and kanamycin sulfate after systemic administration in ponies. J Vet Pharmacol Ther. 1988 Mar;11(1):56-62 |
| 规格 | 100mg 10mM*1mL in Water 200mg 500mg 1g |
| 单位 | 瓶 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
34004200
Development of a streptavidin-bridged enhanced sandwich ELISA based on self-paired nanobodies for monitoring multiplex Salmonella serogroups
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Author：
Yarong Ren, Juan Wei, Ye Wang, Peng Wang, Yanwei Ji, Baoyuan Liu, Jianlong Wang, Gualberto González-Sapienza, Yanru Wang
IF：
6.9110
Publish_to：
ANALYTICA CHIMICA ACTA
PMID：
35361433
Theoretical insights into the mechanism underlying aflatoxin B1 transformation by the BsCotA-methyl syringate system
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Author：
Xiaolu Wang, Lin Cui, Mengting Liu, Zheng Qi, Huiying Luo, Huoqing Huang, Tao Tu, Xing Qin, Yuan Wang, Jie Zhang, Yaru Wang, Bin Yao, Yingguo Bai, Xiaoyun Su
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38301584
Micafungin: A promising inhibitor of UBE2M in cancer cell growth suppression
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Author：
M.A.A. Mamun, Shuan Liu, Lijie Zhao, Lijuan Zhao, Zhong-Rui Li, Dandan Shen, Yu Zheng, Yi-Chao Zheng, Hong-Min Liu
IF：
6.7000
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
37651876
Two triphosphate tunnel metalloenzymes from apple exhibit adenylyl cyclase activity
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Author：
Yuan Ye, Liu Zhiguo, Wang Lili, Wang Lixin, Chen Shuangjiang, Niu Yahong, Zhao Xin, Liu Ping, Liu Mengjun
IF：
6.6270
Publish_to：
Frontiers in Plant Science
PMID：
36275530
The B-box zinc finger protein MdBBX20 integrates anthocyanin accumulation in response to ultraviolet radiation and low temperature
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Author：
Fang H. Dong Y. Yue X. Hu J. Jiang S. Xu H. Wang Y
IF：
6.5500
Publish_to：
Plant Cell Environ
PMID：
30919454
Engineering of 2D artificial nanozyme-based blocking effect-triggered colorimetric sensor for onsite visual assay of residual tetracycline in milk
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Author：
Shen Yizhong, Wei Yunlong, Liu Zhenmin, Nie Chao, Ye Yingwang
IF：
6.4080
Publish_to：
MICROCHIMICA ACTA
PMID：
35622176
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1
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Author：
Ming Wang, Shanfa Ren, Zhun Bi, Liang Zhang, Mengqi Cui, Ronghao Sun, Jiali Bao, Dandi Gao, Bo Yang, Xiaoping Li, Mingjiang Li, Ting Xiao, Hong-gang Zhou, Cheng Yang
IF：
6.3880
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
35229382
Zwitterionic peptide-functionalized highly dispersed carbon nanotubes for efficient wastewater treatment
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Author：
Jie Huang, Xiaojie Sui, Haishan Qi, Xiang Lan, Simin Liu, Lei Zhang
IF：
6.3310
Publish_to：
Journal of Materials Chemistry B
PMID：
35043824
Enhancing the Catalytic Activity of Type II L-Asparaginase from Bacillus licheniformis through Semi-Rational Design
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Author：
Yawen Zhou;Linshu Jiao;Juan Shen;Huibing Chi;Zhaox
IF：
6.2080
Publish_to：
International Journal of Molecular Sciences
PMID：
36077061
Histidine-Rich Protein Accelerates the Biomineralization of Zeolitic Imidazolate Frameworks for In Vivo Protein Delivery
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Author：
Qizhen Zheng, Jinhan Sheng, Ji Liu, Xianghan Chen, Ming Wang
IF：
6.2000
Publish_to：
BIOMACROMOLECULES
PMID：
37859395
Selenium nanoparticle rapidly synthesized by a novel highly selenite-tolerant strain Proteus penneri LAB-1
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Author：
Mingshi Wang, Daihua Jiang, Xuejiao Huang
IF：
6.1070
Publish_to：
iScience
PMID：
36097619
Restricting Promiscuity of Plant Flavonoid 3′-Hydroxylase and 4′-O-Methyltransferase Improves the Biosynthesis of (2S)-Hesperetin in E. coli
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Author：
Juan Liu, Zhiqiang Xiao, Siqi Zhang, Zhen Wang, Yun Chen, Yang Shan
IF：
6.1000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
37310069
Screening of antibiotics to obtain axenic cell cultures of a marine microalga Chrysotila roscoffensis
点击查看 >>
Author：
Jiaojiao Liu, Yan Sun, Lin Zhang, Xiaohui Li, Zhichao He, Chengxu Zhou, Jichang Han
IF：
6.0640
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
37304139
A label-free colorimetric aptasensor based on split aptamers-chitosan oligosaccharide-AuNPs nanocomposites for sensitive and selective detection of kanamycin
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Author：
Xiaoyan Qi, Yinglin Zhao, Haipeng Su, Lele Wang, Ling Li, Rui Ma, Xiaochen Yan, Jianan Sun, Sai Wang, Xiangzhao Mao
IF：
6.0570
Publish_to：
TALANTA
PMID：
34857350
Rationally designed highly amphipathic antimicrobial peptides demonstrating superior bacterial selectivity relative to the corresponding α-helix peptide
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Author：
Jingying Zhang, Anqi Chu, Xu Ouyang, Beibei Li, Ping Yang, Zufang Ba, Yinyin Yang, Wenbo Mao, Chao Zhong, Sanhu Gou, Yun Zhang, Hui Liu, Jingman Ni
IF：
6.0000
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
39864138
Substrates and Loaded Iron Ions Relative Position Influence the Catalytic Characteristics of the Metalloenzymes Angelica archangelica Flavone Synthase I and Camellia sinensis Flavonol Synthase
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Author：
Wang Zhen, Liu An, Liu Juan, Huang Xu, Xiao Feiyao, Tian Miaomiao, Ding Shenghua, Qin Si, Shan Yang
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35754498
Structure–Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification
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Author：
Hua Yang, Ruxue Yan, Yue Li, Zhaoxin Lu, Xiaomei Bie, Haizhen Zhao, Fengxia Lu, Meirong Chen
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
35613468
Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress
点击查看 >>
Author：
Chen W; Wu C; Chen Y; Guo Y; Qiu L; Liu Z; Sun H;
IF：
5.8000
Publish_to：
Int J Oral Sci
PMID：
33753723
Development of CRISPR-CAS9 based RNA drugs against Eimeria tenella infection
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Author：
Muhammad Mohsin, Yige Li, Xin Zhang, Yilei Wang, Zhijian Huang, Guangwen Yin, Ziping Zhang
IF：
5.7360
Publish_to：
GENOMICS
PMID：
34740777
Improved catalytic performance and molecular insight for lipoxygenase from Enterovibrio norvegicus via directed evolution
点击查看 >>
Author：
Bingjie Zhang, Huibing Chi, Juan Shen, Yang Tao, Zhaoxin Lu, Fengxia Lu, Ping Zhu
IF：
5.7000
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
38047284
Iocasia fonsfrigidae NS-1 gen. nov., sp. nov., a Novel Deep-Sea Bacterium Possessing Diverse Carbohydrate Metabolic Pathways
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Author：
Jing Zhang, Yuechao Zhang, Rui Liu, Ruining Cai, Fanghua Liu, Chaomin Sun
IF：
5.6400
Publish_to：
Frontiers in Microbiology
PMID：
34899621
Comprehensive Metabolite Profile Uncovers the Bioactive Components，Antioxidant and Antibacterial Activities in Wild Tree Peony Leaves
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Author：
Ziwei Xin，Weizong Yang，Lixin Niu，Yanlong Zhang
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
37445786
Metabolic responses of indigenous bacteria in chicken faeces and maggots to multiple antibiotics via heavy water labeled single-cell Raman spectroscopy
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Author：
Oladipo Oladiti Olaniyi, Hongzhe Li, Yongguan Zhu, Li Cui
IF：
5.5650
Publish_to：
Journal of Environmental Sciences
PMID：
34963547
Characterization and Preliminary Application of a Novel Lipoxygenase from Enterovibrio norvegicus
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Author：
Bingjie Zhang, Meirong Chen, Bingjie Xia, Zhaoxin Lu, Kuan Shiong Khoo, Pau Loke Show, Fengxia Lu
IF：
5.5610
Publish_to：
Foods
PMID：
36140992
Heat stress enhanced perylenequinones biosynthesis of Shiraia sp. Slf14(w) through nitric oxide formation
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Author：
Xu Chenglong, Lin Wenxi, Chen Yunni, Gao Boliang, Zhang Zhibin, Zhu Du
IF：
5.5600
Publish_to：
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
PMID：
37126084
Overexpression of a Cotton Aquaporin Gene GhTIP1;1-like Confers Cold Tolerance in Transgenic Arabidopsis
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Author：
ChengG;WangM;ZhangL;WeiH;WangH;LuJ;YuS
IF：
5.5420
Publish_to：
Int J Mol Sci
PMID：
35163287
Regiodivergent and stereoselective hydroxyazidation of alkenes by biocatalytic cascades
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Author：
Jing-Fei Wu, Nan-Wei Wan, Ying-Na Li, Qing-Ping Wang, Bao-Dong Cui, Wen-Yong Han, Yong-Zheng Chen
IF：
5.4580
Publish_to：
iScience
PMID：
34401667
Interaction between MdWRKY55 and MdNAC17-L enhances salt tolerance in apple by activating MdNHX1 expression
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Author：
Mengyu Su, Shuo Wang, Wenjun Liu, Ming Yang, Zongying Zhang, Nan Wang, Xuesen Chen
IF：
5.3630
Publish_to：
PLANT SCIENCE
PMID：
35643619
Directed evolution of a carbonyl reductase LsCR for the enantioselective synthesis of (1S)-2-chloro-1-(3,4-difluorophenyl) ethanol
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Author：
Hua-Tao Liu, Chun-Yue Weng, Shen-Yuan Xu, Shu-Fang Li, Ya-Jun Wang, Yu-Guo Zheng
IF：
5.3070
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
35816872
Immunogenicity and safety of a self-assembling ZIKV nanoparticle vaccine in mice
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Author：
Ting Liu, Meng Li, Yang Tian, Yuhan Dong, Nan Liu, Zengming Wang, Hui Zhang, Aiping Zheng, Chunying Cui
IF：
5.3000
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
38866086
Preparation of Sulforaphene from Radish Seed Extracts with Recombinant Food-Grade Yarrowia lipolytica Harboring High Myrosinase Activity
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Author：
Lili Wang, Hong Jiang, Xingxing Liang, Wenting Zhou, Yanjun Qiu, Changhu Xue, Jianan Sun, Xiangzhao Mao
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
33929187
Activity of the lyases LysSSE1 and HolSSE1 against common pathogenic bacteria and their antimicrobial efficacy in biofilms
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Author：
Han Lu, Wenbin Xiong, Zong Li, Bingxin Liu, Ruyin Liu, Xinchun Liu
IF：
5.2750
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
34488127
Engineering a Xylose-Utilizing Synechococcus elongatus UTEX 2973 Chassis for 3-Hydroxypropionic Acid Biosynthesis under Photomixotrophic Conditions.
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Author：
Yao J; Wang J; Ju Y; Dong Z; Song X; Chen L; Zhang
IF：
5.2290
Publish_to：
ACS Synth Biol
PMID：
35119824
Molecular characterization and expression analysis of the critical floral gene MdAGL24-like in red-fleshed apple
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Author：
Su M; Wang N; Jiang S; Fang H; Xu H; Wang Y; Zhang Z; Zhang J; Xu L; Zhang Z; Chen X.
IF：
5.2000
Publish_to：
Plant Science
PMID：
30348318
Improving Degradation of Polycyclic Aromatic Hydrocarbons by Bacillus atrophaeus Laccase Fused with Vitreoscilla Hemoglobin and a Novel Strong Promoter Replacement
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Author：
Luyao Wang, Yuzhi Tan, Shengwei Sun, Liangjie Zhou, Guojun Wu, Yuting Shao, Mengxi Wang, Zhihong Xin
IF：
5.1680
Publish_to：
Biology-Basel
PMID：
36009756
Enantiocomplementary synthesis of β-adrenergic blocker precursors via biocatalytic nitration of phenyl glycidyl ethers
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Author：
Hui-Hui Wang, Nan-Wei Wan, Xin-Yu Da, Xue-Qing Mou, Zhu-Xiang Wang, Yong-Zheng Chen, Zhi-Qiang Liu, Yu-Guo Zheng
IF：
5.1000
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
37320911
Insecticidal Activity of Chitinases from Xenorhabdus nematophila HB310 and Its Relationship with the Toxin Complex
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Author：
Jia Liu, Hui Bai, Ping Song, Ziyan Nangong, Zhiping Dong, Zhiyong Li, Qinying Wang
IF：
5.0750
Publish_to：
Toxins
PMID：
36136584
Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis
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Author：
Fu G; Liu J; Li J; Zhu B; Zhang D
IF：
5.0370
Publish_to：
J Agric Food Chem
PMID：
30463403
Impacts of salt-tolerant Staphylococcus nepalensis 5-5 on bacterial composition and biogenic amines accumulation in fish sauce fermentation.
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Author：
Ma X; Zhang Y; Li X; Bi J; Zhang G; Hao H; Hou H.
IF：
5.0330
Publish_to：
Int J Food Microbiol
PMID：
34749187
Organic Hydroperoxide Induces Prodigiosin Biosynthesis in Serratia sp. ATCC 39006 in an OhrR-Dependent Manner
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Author：
Di Sun, Weijie Liu, Xuge Zhou, Yunrui Ru, Jiawen Liu, Jingrong Zhu, Cong Liu
IF：
5.0050
Publish_to：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
PMID：
35044847
Characterization of bifunctional alginate lyase Aly644 and antimicrobial activity of enzymatic hydrolysates
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Author：
Zhang Ao, Cao Zhe, Zhao Luying, Zhang Qian, Fu Liping, Li Jiang, Liu Tao
IF：
5.0000
Publish_to：
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
PMID：
37698609
Thermostability Improvement of L-Asparaginase from Acinetobacter soli via Consensus-Designed Cysteine Residue Substitution
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Author：
Linshu Jiao, Huibing Chi, Bingjie Xia, Zhaoxin Lu, Xiaomei Bie, Haizhen Zhao, Fengxia Lu, Meirong Chen
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36235209
A comprehensive description of the TolC effect on the antimicrobial susceptibility profile in Enterobacter bugandensis
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Author：
Li B; Zhang J; Li X
IF：
4.8310
Publish_to：
Front Cell Infect Microbiol
PMID：
36569193
Culture-free identification of fast-growing cyanobacteria cells by Raman-activated gravity-driven encapsulation and sequencing
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Author：
Jinyu Cui, Rongze Chen, Huili Sun, Yingyi Xue, Zhidian Diao, Jingyun Song, Xiaohang Wang, Jia Zhang, Chen Wang, Bo Ma, Jian Xu, Guodong Luan, Xuefeng Lu
IF：
4.8000
Publish_to：
Synthetic and Systems Biotechnology
PMID：
38053584
Efficient One-Step Biocatalytic Multienzyme Cascade Strategy for Direct Conversion of Phytosterol to C-17-Hydroxylated Steroids
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Author：
Rui Tang, Xiaoxian Ren, Menglei Xia, Yanbing Shen, Linna Tu, Jianmei Luo, Qi Zhang, Yuying Wang, Peilin Ji, Min Wang
IF：
4.7920
Publish_to：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
PMID：
34586911
4-(8-(4-Methylimidazole)-octyloxy)-arctigenin: The first inhibitor of fish rhabdovirus glycoprotein
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Author：
Wei-Chao Chen, Fei Luo, Tao Wang, Gao-Xue Wang
IF：
4.7000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
37385462
Identification of zebrafish PLEKHF2 presents in egg/embryos as an antibacterial protein
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Author：
Yiqing Ren, Chunqiu Wang, Hao Wang, Qingqi Chang, Dongqiu Guo, Xia Wang
IF：
4.6220
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
35863537
Biocatalytic hydroxylation tertiary C-H bonds for synthesis of chiral tertiary alcohols by cytochrome P450
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Author：
Ru-Yue Zhang, Ting Ma, Dan Liu, Yu-Li Yang, Luo Gao, Hai-Bo Cui, Zhong-Qiang Wang, Yong-Zheng Chen
IF：
4.6000
Publish_to：
Molecular Catalysis
PMID：
Ultraviolet B-induced MdWRKY72 expression promotes anthocyanin synthesis in apple
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Author：
Hu J. Fang H. Wang J. Yue X. Su M. Mao Z. Zou Q. J
IF：
4.5380
Publish_to：
Plant Sci
PMID：
32005382
Tuning enzymatic properties by protein engineering toward catalytic tetrad of carbonyl reductase
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Author：
Feng Cheng, Qiu-Yao Zhai, Xiao-Fan Gao, Hua-Tao Liu, Shuai Qiu, Ya-Jun Wang, Yu-Guo Zheng
IF：
4.5300
Publish_to：
BIOTECHNOLOGY AND BIOENGINEERING
PMID：
34436762
Establishment of a Rapid and Effective Agrobacterium-Mediated Genetic Transformation System of Oxalis triangularis ‘Purpurea’
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Author：
Yun Xiao, Wanli Tuo, Xuexuan Wang, Baomin Feng, Xinyu Xu, Sagheer Ahmad, Junwen Zhai, Donghui Peng, Shasha Wu
IF：
4.5000
Publish_to：
Plants-Basel
PMID：
38140457
Identification and pharmacological characterization of the voltage-gated potassium channel Shab in diamondback moth, Plutella xylostella
点击查看 >>
Author：
Xiaoyi Huo, Haihao Ma, Hang Zhu, Jia Liu, Yong Zhou, Xiaomao Zhou, Zheming Liu
IF：
4.4620
Publish_to：
PEST MANAGEMENT SCIENCE
PMID：
36418849
Identification and functional analysis of the mitochondrial cysteine synthase TtCsa2 from Tetrahymena thermophila
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Author：
Hongrui Lv, Lina Hu, Jing Xu, Tao Bo, Wei Wang
IF：
4.4290
Publish_to：
JOURNAL OF CELLULAR BIOCHEMISTRY
PMID：
34427342
Simultaneous Quantification of Ampicillin and Kanamycin in Water Samples Based on Lateral Flow Aptasensor Strip with an Internal Line
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Author：
Jinbiao Lin, Ang Shi, Ziwu Zheng, Long Huang, Yixin Wang, Honggui Lin, Xuexia Lin
IF：
4.4120
Publish_to：
MOLECULES
PMID：
34206584
Bioinformatic and Functional Characterization of Hsp70s in Myxococcus xanthus
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Author：
Zhuo Pan, Zheng Zhang, Li Zhuo, Tian-yu Wan, Yue-zhong Li
IF：
4.3890
Publish_to：
mSphere
PMID：
34011688
Quorum Quenching Enzyme (PF-1240) Capable to Degrade AHLs as a Candidate for Inhibiting Quorum Sensing in Food Spoilage Bacterium Hafnia alvei
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Author：
Yue Shen, Fangchao Cui, Dangfeng Wang, Tingting Li, Jianrong Li
IF：
4.3500
Publish_to：
Foods
PMID：
34828982
Engineering a non-oxidative glycolysis pathway in escherichia coli for high-level citramalate production
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Author：
Wang Tingting, Ding Lijuan, Luo Huiying, Huang Huoqing, Su Xiaoyun, Bai Yingguo, Tu Tao, Wang Yuan, Qin Xing, Zhang Honglian, Wang Yaru, Yao Bin, Zhang Jie, Wang Xiaolu
IF：
4.3000
Publish_to：
Microbial Cell Factories
PMID：
39174991
Systematic screening reveals synergistic interactions that overcome MAPK inhibitor resistance in cancer cells
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Author：
Yu Yu, Minzhen Tao, Libin Xu, Lei Cao, Baoyu Le, Na An, Jilin Dong, Yajie Xu, Baoxing Yang, Wei Li, Bing Liu, Qiong Wu, Yinying Lu, Zhen Xie, Xiaohua Lian
IF：
4.2480
Publish_to：
Cancer Biology & Medicine
PMID：
34106558
Investigation of indole biodegradation by Cupriavidus sp. strain IDO with emphases on downstream biotransformation and indigo production
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Author：
Dai
Chunxiao, Ma Fang, Ma Qiao, Yang Jing, Li Yan, Yang Bingyu, Qu Yuanyuan
IF：
4.2230
Publish_to：
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
PMID：
34490563
An Integrated Strategy Based on 10-DAB Extraction and In Situ Whole-Cell Biotransformation of Renewable Taxus Needles to Produce Baccatin III
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Author：
Ping Kou, Yingying Yu, He Wang, Yuchi Zhang, Zhaoxia Jin, Fang Yu
IF：
4.2000
Publish_to：
MOLECULES
PMID：
38893462
Identification and characterization of ι-carrageenase from macroalgae-associated bacterium Microbulbifer sp. YNDZ01
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Author：
Qian Zhang, Yuanyuan Gui, Luying Zhao, Ao Zhang, Liping Fu, Zhe Cao, Jiang Li
IF：
4.1250
Publish_to：
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
PMID：
37209381
Copper Resistance Mechanism and Copper Response Genes in Corynebacterium crenatum
点击查看 >>
Author：
Mingzhu Huang, Wenxin Liu, Chunyan Qin, Yang Xu, Xu Zhou, Qunwei Wen, Wenbin Ma, Yanzi Huang, Xuelan Chen
IF：
4.1000
Publish_to：
Microorganisms
PMID：
38792781
Engineering an electroactive Escherichia coli for the microbial electrosynthesis of succinate by increasing the intracellular FAD pool
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Author：
WuZ;WangJ;ZhangX;etal
IF：
3.9370
Publish_to：
Biochemical Engineering Journal
PMID：
Expression and biological activity of lytic proteins HolST-3 and LysST-3 of Salmonella phage ST-3
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Author：
Bingxin Liu, Han Lu, Zong Li, Peihan Yan, Ruyin Liu, Xinchun Liu
IF：
3.8480
Publish_to：
MICROBIAL PATHOGENESIS
PMID：
35697172
Coevolving stability and activity of LsCR by a single point mutation and constructing neat substrate bioreaction system
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Author：
Hua-Tao Liu, Chun-Yue Weng, Lei Zhou, Hao-Bo Xu, Zhen-Yu Liao, Han-Yue Hong, Yuan-Fan Ye, Shu-Fang Li, Ya-Jun Wang, Yu-Guo Zheng
IF：
3.8000
Publish_to：
BIOTECHNOLOGY AND BIOENGINEERING
PMID：
36799475
Immobilized Dipeptidase in Manganese Ion-Loaded Polyethylenimine-Induced Calcium Phosphate Nanocrystals for Carnosine Synthesis
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Author：
Yujia Liu, Jie Yu, Yan Sun
IF：
3.7000
Publish_to：
LANGMUIR
PMID：
38693862
Production of hesperetin from naringenin in an engineered Escherichia coli consortium
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Author：
Juan Liu, Miaomiao Tian, Zhen Wang, Feiyao Xiao, Xu Huang, Yang Shan
IF：
3.5950
Publish_to：
JOURNAL OF BIOTECHNOLOGY
PMID：
35192875
Evidence of a shared binding site for Bacillus thuringiensis Cry1Ac and Cry2Aa toxins in Cnaphalocrocis medinalis cadherin
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Author：
J. Zhong, S. Fang, M. Gao, L. Lu, X. Zhang, Q. Zhu, Y. Liu, J. L. Jurat-Fuentes, X. Liu
IF：
3.5850
Publish_to：
INSECT MOLECULAR BIOLOGY
PMID：
34637177
Development of fluorescent aptasensing system for ultrasensitive analysis of kanamycin - ScienceDirect
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Author：
ZhouY;ZuoL;WeiY;etal
IF：
3.5810
Publish_to：
Journal of Luminescence
PMID：
Microfluidic Chip for Detection of Drug Resistance at the Single-cell Level
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Author：
Kena Song, Zhangqing Yu, Xiangyang Zu, Lei Huang, Dongliao Fu, Jingru Yao, Zhigang Hu, Yun Xue
IF：
3.5230
Publish_to：
Micromachines
PMID：
36677107
Engineered Pichia pastoris production of fusaruside; a selective immunomodulator
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Author：
Tian Y; Li Y; Zhao F; Meng C
IF：
3.5000
Publish_to：
BMC Biotechnol
PMID：
31208387
Characterization of polyphosphate kinases for the synthesis of GSH with ATP regeneration from AMP
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Author：
Caixia Cui, Mengyuan Kong, Yihan Wang, Chenyan Zhou, Hong Ming
IF：
3.4930
Publish_to：
ENZYME AND MICROBIAL TECHNOLOGY
PMID：
34311890
Development and application of an indirect ELISA to detect antibodies to Neospora caninum in cattle based on a chimeric protein rSRS2-SAG1-GRA7
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Author：
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3.4710
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36590802
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33423191
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Plant Cell Tissue and Organ Culture
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Analytical Methods
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35006220
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FEMS MICROBIOLOGY LETTERS
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35798009
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2.8120
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FUNCTIONAL PLANT BIOLOGY
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35577345
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2.8000
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JOURNAL OF SEPARATION SCIENCE
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39319600
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
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34515139
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BIOTECHNOLOGY LETTERS
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37589824
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2.5520
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ARCHIVES OF MICROBIOLOGY
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34057548
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Li Zhao, Huizheng Wang, Zanxia Cao, Qiang Li, Zhenghua Li, Liling Zhao, Ying Liu, Zhenling Huang, Enguang Lv
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2.5000
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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39461008
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Wang Zhen, Huang Xu, Liu Juan, Xiao Feiyao, Tian Miaomiao, Ding Shenghua, Shan Yang
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2.4610
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BIOTECHNOLOGY LETTERS
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34514540
Molecular cloning and characterization of a thermostable and halotolerant endo-β-1,4-glucanase from Microbulbifer sp. ALW1
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3 Biotech
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33968593
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PROTEIN JOURNAL
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33721189
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ARCHIVES OF MICROBIOLOGY
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39419831
In silico and experimental methods for designing a potent anticancer arazyme-herceptin fusion protein in HER2-positive breast cancer
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Rahmani Farideh, Imani Fooladi Abbas Ali, Ajoudanifar Hatef, Soleimani Nazila Arbab
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2.2000
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37103612
Computational and in vitro targeting of HUVECs by ARA-Linker-TGFαL3 through VEGFR2
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2.1000
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MOLECULAR SIMULATION
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Activity of coumarin against Candida albicans biofilms
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Xu K;Wang JL;Chu MP;Jia C.
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1.4790
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J Mycol Med.
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30606640
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Pan-Pan Jia, Xiang-Ru Liu, Ming-Fei Wu, Yan Li, Lan-Chen Zhang, De-Sheng Pei
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1.2000
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Jove-Journal of Visualized Experiments
PMID：
38682933
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