国内地区 :
欢迎光临,!登录 | 注册
产品中心

活动

阿糖胞苷

CAS:No.147-94-4

英文名称:Cytarabine

分子式:C9H13N3O5

分子量:243.22

储存条件:Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year

纯度:HPLC≥98%

阿糖胞苷
小分子同系列3送1
货号:
IC0630
品牌:
Solarbio
SKU 北京总部 北京海淀 武汉 广州
IC0630-W-1ml 咨询 咨询 咨询 咨询
IC0630-100mg 咨询 咨询 咨询 咨询
IC0630-500mg 咨询 咨询 咨询 咨询
IC0630-50mg 咨询 咨询 咨询 咨询
IC0630-1g 咨询 咨询 咨询 咨询
数量:
-
+
立即购买

使用本产品的案例(仅供参考

In Vitro

Cell(K562 cells;0.1 ng/mL cytarabine;5d)

K562 cells were cultured in RPMI-1640 medium containing 10% fetal bovine serum and 1% penicillin and streptomycin. K562 cells were differentiated by erythroid induction at an initial concentration of 1 × 105 /mL cells. A final concentration of 40 μM hemin (Solarbio, China) and 0.1 ng/mL cytarabine (Solarbio, China) were added to the medium to induce erythroid differentiation, and the cells were placed at 37°C under hypoxic (5% CO2, 5% O2), CoCl (200 μM) and normoxic (5% CO2, 20% O2) conditions for 5 days.

来源文献:Gao Z, Li Z, Li X, Xiao J, Li C. Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions. Front Cell Dev Biol. 2023 Jun 1;11:1161541. doi: 10.3389/fcell.2023.1161541. PMID: 37325570; PMCID: PMC10267359.


In Vivo

Mice(50~200 mg/kgAra-C,腹腔注射,7d

After a week to adapt to the facility, mice were randomly divided into four groups (n = 10 mice per group) for intestinal pathology and survival analysis in the selection of the optimal doses of Ara-C. Ara-C and AS-IV were dissolved by 0.9% saline and dimethyl sulfoxide(DMSO) respectively. The control group was injected intraperitoneally with 0.9% saline (5 ml/kg) and the Ara-C group was intraperitoneally injected with different doses of Ara-C (50 mg/kg, 100 mg/kg, 200 mg/kg) for 7 days. Mice were killed at day 10.  

来源文献:Li JJ, Li YL, Chu W, Li GQ, Zhang M, Dong JJ, Li L, Li CH, Zhang JB, Li JW, Jin XJ, Liu YQ. Astragaloside IV alleviates cytarabine-induced intestinal mucositis by remodeling macrophage polarization through AKT signaling. Phytomedicine. 2023 Jan;109:154605. doi: 10.1016/j.phymed.2022.154605. Epub 2022 Dec 15. PMID: 36610133.



备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.

实验图
暂无详情
Li JJ, et al. Phytomedicine. 2023 Jan;109154605.
Li JJ, et al. Phytomedicine. 2023 Jan;109154605.
Gao Z, Li Z, Li X, Xiao J, Li C. Front Cell Dev Biol. 2023 Jun 1;11:1161541.
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
为科研服务、为生命尽责
联系方式
地址: 北京市通州区马驹桥联东U谷85号
客服电话: 400-968-6088
技术邮箱: service@solarbio.com
采购邮箱: purchase@solarbio.com
销售邮箱: sales-china@solarbio.com
Copyright © 2004-2022 北京索莱宝科技有限公司. 版权所有.
 京ICP备12051307号-7 
京公网安备 11011202000391号