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MTT试剂盒/细胞毒性检测试剂盒/细胞增殖检测试剂盒
英文名称:MTT Cell Proliferation and Cytotoxicity Assay Kit
储存条件:-20℃，避光，有效期1年
产品简介
| 英文名称 | MTT Cell Proliferation and Cytotoxicity Assay Kit |
| 中文名称 | MTT试剂盒/细胞毒性检测试剂盒/细胞增殖检测试剂盒 |
| 储存条件 | -20℃，避光，有效期1年 |
| 规格 | 500T 1000T |
| 单位 | 盒 |
产品简介：
MTT可以被线粒体内的一些脱氢酶还原生成结晶状的深紫色产物formazan，在特定溶剂存在的情况下，可以被完全溶解，然后通过酶标仪可以测定490nm波长附近的吸光度。细胞增殖越多越快，则吸光度越高；细胞毒性越大，则吸光度越低。
使用说明：
1.收集对数期细胞，调整细胞悬液浓度，分于96孔板，每孔180μL，3000-10000个细胞/孔。
2.置37℃、5%CO2温箱培养使细胞贴壁，培养6-24小时。
3.加入适当浓度的受试化合物，继续培养适当时间。
4.小心吸去上清，加入90μL新鲜培养液，再加入10μL MTT溶液，继续培养4 h。
5.然后吸掉上清，每孔加入110μL Formazan溶解液，置摇床上低速振荡10 min，使结晶物充分溶解。在酶联免疫检测仪490 nm处测量各孔的吸光值。
6.同时设置调零孔（培养基、MTT、 Formazan溶解液），对照孔（细胞、相同浓度的药物溶解介质、培养液、MTT、 Formazan溶解液），每组设定3复孔。
注意事项：
1.由于使用96孔板进行检测，如果细胞培养时间较长，一定要注意蒸发的问题。一方面，由于96孔板周围一圈最容易蒸发，可以采取弃用周围一圈的办法，改加PBS，水或培养液；另一方面，可以把96孔板置于靠近培养箱内水源的地方，以缓解蒸发。
2.MTT溶液为黄色需避光保存，长时间光照会导致失效。当颜色变为灰绿色时，请勿使用。Formazan溶解液结冻或产生沉淀时可以37℃水浴孵育以促进溶解，并且必须在全部溶解并混匀后使用。
3.为了您的安全和健康，请穿实验服并戴一次性手套操作。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
37586621
Gefitinib Reverses PD-L1-Mediated Immunosuppression Induced by long-term Glutamine blockade in Bladder Cancer
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Author：
Ma Guofeng, Jia Huiqing, Li Zhiqiang, Zhang Xiangyan, Wang Liping, Zhang Zhilei, Xiao Yujing, Liang Zhijuan, Li Dan, Chen Yuanbin, Tian Xintao, Wang Yonghua, Liang Ye, Niu Haitao
IF：
8.1000
Publish_to：
Cancer Immunology Research
PMID：
39470699
3D printing of injury-preconditioned secretome/collagen/heparan sulfate scaffolds for neurological recovery after traumatic brain injury in rats
点击查看 >>
Author：
Liu Xiao-Yin, Chang Zhe-Han, Chen Chong, Liang Jun, Shi Jian-Xin, Fan Xiu, Shao Qi, Meng Wei-Wei, Wang Jing-Jing, Li Xiao-Hong
IF：
8.0790
Publish_to：
Stem Cell Research & Therapy
PMID：
36536463
Novel Hydroxychalcone-Based Dual Inhibitors of Aldose Reductase and α-Glucosidase as Potential Therapeutic Agents against Diabetes Mellitus and Its Complications
点击查看 >>
Author：
Xiaonan Zhang, Long Xu, Huan Chen, Xin Zhang, Yanqi Lei, Wenchao Liu, Hulin Xu, Bing Ma, Changjin Zhu
IF：
8.0390
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
PMID：
35749671
Equilibrative nucleoside transporter 3 promotes the progression of hepatocellular carcinoma by regulating the AKT/mTOR signaling pathway
点击查看 >>
Author：
Peifang Qin, Jianguo Yan, Haitao Huang, Qi Wang, Mao Li, Yuting Zhang, Jiahui Wang, Tingting Jiang, Xiaoling Zhang, Yali Zhou
IF：
8.0250
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
37023875
Dynamic Visualization of Endoplasmic Reticulum Stress in Living Cells via a Two-Stage Cascade Recognition Process
点击查看 >>
Author：
Man-Sha Wu, Ze-Rui Zhou, Xiao-Yuan Wang, Bin-Bin Chen, Mahmoud Elsayed Hafez, Ji-Fen Shi, Da-Wei Li, Ruo-Can Qian
IF：
8.0080
Publish_to：
ANALYTICAL CHEMISTRY
PMID：
35112843
A Pegylated Liposome Loaded with Raddeanin A for Prostate Cancer Therapy
点击查看 >>
Author：
Kang He, Taiwei Wang, Junyu Chen, Xuemiao Huang, Zeyu Wang, Zhaoyun Yang, Kai Wang, Weixin Zhao, Jian Jiang, Lijing Zhao
IF：
8.0000
Publish_to：
International Journal of Nanomedicine
PMID：
37496689
Bioinformatics-driven discovery of silica nanoparticles induces apoptosis and renal damage via the unfolded protein response in NRK-52E cells and rat kidney
点击查看 >>
Author：
Naimeng Liu, Meng Li, Huan Pang, Tian Tiantian, Xinyue Li, Yanchi Su, Minghua Jin, Hao Wu, Chuyue Qian, Mindan Sun
IF：
7.7000
Publish_to：
COMPUTERS IN BIOLOGY AND MEDICINE
PMID：
38064850
Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer
点击查看 >>
Author：
Shuang-Ling Wu, Xiaoyi Zhang, Mengqi Chang, Changcai Huang, Jun Qian, Qing Li, Fang Yuan, Lihong Sun, Xinmiao Yu, Xinmiao Cui, Jiayi Jiang, Mengyao Cui, Ye Liu, Huan-Wen Wu, Zhi-Yong Liang, Xiaoyue Wang, Yamei Niu, Wei-Min Tong, Feng Jin
IF：
7.6910
Publish_to：
GENOMICS PROTEOMICS & BIOINFORMATICS
PMID：
33716151
Therapeutic Effects of Crocin Alone or in Combination with Sorafenib against Hepatocellular Carcinoma: In Vivo & In Vitro Insights
点击查看 >>
Author：
Suzan Abdu, Nouf Juaid, Amr Amin, Mohamed Moulay, Nabil Miled
IF：
7.6750
Publish_to：
Antioxidants
PMID：
36139719
Microplastics exposure disrupts nephrogenesis and induces renal toxicity in human iPSC-derived kidney organoids
点击查看 >>
Author：
Bingrui Zhou, Yunliang Wei, Long Chen, Anxiu Zhang, Ting Liang, Jian Hui Low, Zhizhen Liu, Sheng He, Zhongyuan Guo, Jun Xie
IF：
7.6000
Publish_to：
ENVIRONMENTAL POLLUTION
PMID：
39095001
FoxO3 Modulates LPS-Activated Hepatic Inflammation in Turbot (Scophthalmus maximus L.)
点击查看 >>
Author：
Pan Mingzhu, Liu Jiahuan, Huang Dong, Guo Yanlin, Luo Kai, Yang Mengxi, Gao Weihua, Xu Qiaoqing, Zhang Wenbing, Mai Kangsen
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
34276667
Amphiphilic hydroxyethyl starch-based nanoparticles carrying linoleic acid modified berberine inhibit the expression of krasv12 oncogene in zebrafish
点击查看 >>
Author：
Xiaoming Yu, Wenbin Zhao, Qinglin Zou, Lizhen Wang
IF：
7.5000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38795642
Metformin protects fibroblasts from patients with GNE myopathy by restoring autophagic flux via an AMPK/mTOR-independent pathway
点击查看 >>
Author：
Tongtong Zhang, Xiang Yin, Xuefan Yu, Ren Shang, Liuzhe Lu, Jing Miao
IF：
7.4190
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
37263165
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis
点击查看 >>
Author：
Lulu Guan, Feifei Wang, Mengjiao Wang, Songfeng Han, Zhaohai Cui, Shoumin Xi, Haixu Xu, Shipeng Li
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
35615577
Digoxin protects against intervertebral disc degeneration via TNF/NF-百B and LRP4 signaling
点击查看 >>
Author：
Qunbo Meng, Kaiwen Liu, Zhenchuan Liu, Jinbo Liu, Ziyu Tian, Shanshan Qin, Jianlu Wei, Lei Cheng
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
37790932
Autophagy-mediated ferroptosis involved in nickel-induced nephrotoxicity in the mice
点击查看 >>
Author：
Qing Yang, Zhicai Zuo, Yuxin Zeng, Yujuan Ouyang, Hengmin Cui, Huidan Deng, Yanqiu Zhu, Junliang Deng, Yi Geng, Ping Ouyang, Weiming Lai, Zongjun Du, Xueqin Ni, Heng Yin, Jing Fang, Hongrui Guo
IF：
7.1290
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
37235900
Combined Ferromagnetic Nanoparticles for Effective Periodontal Biofilm Eradication in Rat Model
点击查看 >>
Author：
Fei Tong, Pei Wang, Ziqiang Chen, Yifan Liu, Lianguo Wang, Jun Guo, Zhihua Li, Hu Cai, Junchao Wei
IF：
7.0330
Publish_to：
International Journal of Nanomedicine
PMID：
37192894
Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice
点击查看 >>
Author：
Jing Qi, Lanqian Li, Xueqing Yan, Wenxi Hua, Zixiong Zhou
IF：
7.0000
Publish_to：
Antioxidants
PMID：
37760020
Characterization of a neutral polysaccharide from pumpkin (Cucurbita moschata Duch) with potential immunomodulatory activity
点击查看 >>
Author：
Linlin Huang, Jing Zhao, Yunlu Wei, Guoyong Yu, Quanhong Li
IF：
6.9530
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
34389393
Cyy-272, an indazole derivative, effectively mitigates obese cardiomyopathy as a JNK inhibitor
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Author：
Xin Liu, Lin-ting Cheng, Qian-ru Ye, Hao-cheng Gao, Jin-wei Zhu, Kai Zhao, Hua-min Liu, Yun-jie Wang, Tahereh Alinejad, Xiu-hua Zhang, Gao-zhi Chen
IF：
6.9000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
39128188
Hybrid-cell membrane-coated nanocomplex-loaded chikusetsusaponin IVa methyl ester for a combinational therapy against breast cancer assisted by Ce6
点击查看 >>
Author：
Qian Xie, Yang Liu, Ying Long, Zhou Wang, Sai Jiang, Rida Ahmed, Muhammad Daniyal, Bin Li, Bin Liu, Wei Wang
IF：
6.8430
Publish_to：
Biomaterials Science
PMID：
33651044
Ultrasound microbubble-mediated RNA interference targeting WNT1 inducible signaling pathway protein 1(WISP1) suppresses the proliferation and metastasis of breast cancer cells
点击查看 >>
Author：
Faying Fang, Weizhi Xu, Jian Zhang, Jin Gu, Gaoyi Yang
IF：
6.8320
Publish_to：
Bioengineered
PMID：
35481425
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD)
点击查看 >>
Author：
Xiaojun Zhang, Feng Gao, Huihan Ai, Shuyue Wang, Zhenbo Song, Lihua Zheng, Guannan Wang, Ying Sun, Yongli Bao
IF：
6.8310
Publish_to：
CELL PROLIFERATION
PMID：
33630390
Rational assembly of RGD/MoS2/Doxorubicin nanodrug for targeted drug delivery, GSH-stimulus release and chemo-photothermal synergistic antitumor activity
点击查看 >>
Author：
Chunhong Mo, Zhao Wang, Jianying Yang, Yiqiang Ouyang, Qian Mo, Shuting Li, Ping He, Limin Chen, Xinchun Li
IF：
6.8140
Publish_to：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
PMID：
35679748
Deciphering the impact of greenhouse pesticides on hepatic metabolism profile: Toxicity experiments on HepG2 cells using chlorpyrifos and emamectin benzoate
点击查看 >>
Author：
Yingying Zhang, Yun Pan, Xiangyu Bai, Wen Sun, Xingfan Zhou, Qing Dong, Hui Wang, Yuanbao Zhang, Wenlin Bai, Wenping Zhang
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38552389
Molecular toxicity and defense mechanisms induced by silver nanoparticles in Drosophila melanogaster
点击查看 >>
Author：
Zhidi Wang, Liying Zhang, Xing Wang
IF：
6.7960
Publish_to：
Journal of Environmental Sciences
PMID：
36375944
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway
点击查看 >>
Author：
Jun Chen, Zhiguang Duan, Yannan Liu, Rongzhan Fu, Chenhui Zhu
IF：
6.7060
Publish_to：
Nutrients
PMID：
35893895
Zeolitic Imidazolate Framework-90 loaded with methylprednisolone sodium succinate effectively reduces hypertrophic scar in vivo
点击查看 >>
Author：
Xiaoxiang Xu, Jun Liu, Zixuan Xiao, Shuang Li, Ya Zhang, Peng Song, Kun Lin, Lei Zhang, Haoquan Zheng, Yuye Zhou, Xiong Chen
IF：
6.7000
Publish_to：
Nanoscale
PMID：
38488127
Long Non-coding RNA ASNR Targeting miR-519e-5p Promotes Gastric Cancer Development by Regulating FGFR2
点击查看 >>
Author：
Chen Zihao, Li Yong, Tan Bibo, Li Fang, Zhao Qun, Fan Liqiao, Zhang Zhidong, Zhao Xuefeng, Liu Yu, Wang Dong
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
34307360
Induction of P-glycoprotein expression by dandelion in tumor and heart tissues: Impact on the anti-tumor activity and cardiotoxicity of doxorubicin
点击查看 >>
Author：
Jiameng Qu, Fan Ke, Xiao Yang, Yue Wang, Huarong Xu, Qing Li, Kaishun Bi
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
35760022
Insight into Antiviral Activity of Ag/TiO2 Nanocomposites Against Influenza H1N1 Virus and Its Antiviral Mechanism
点击查看 >>
Author：
Yihe Ma, Xiaojun Xiao, Yutao Wang, Jie Sun, Ping Tang, Jing Li, Xizhuo Sun, Damo Xu, Zifeng Yang, Shiguo Chen, Xiaoyu Liu
IF：
6.6000
Publish_to：
International Journal of Nanomedicine
PMID：
39524926
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism
点击查看 >>
Author：
Fan Pei, Sha Fangfang, Ma Chuan, Wei Qiaohong, Zhou Yaqi, Shi Jing, Fu Jiaojiao, Zhang Lu, Han Bin, Li Jianke
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
35711556
Inhibition of SARS-CoV-2 pseudovirus invasion by ACE2 protecting and Spike neutralizing peptides: An alternative approach to COVID19 prevention and therapy
点击查看 >>
Author：
Jiang Chen, Song Li, Zhifeng Lei, Qinmin Tang, Ling Mo, Xing Zhao, Feifei Xie, Dan Zi, Jun Tan
IF：
6.5820
Publish_to：
International Journal of Biological Sciences
PMID：
34345219
Dihydromyricetin Ameliorates Inflammation-Induced Insulin Resistance via Phospholipase C-CaMKK-AMPK Signal Pathway
点击查看 >>
Author：
Lianjie Hou, Fangyi Jiang, Bo Huang, Weijie Zheng, Yufei Jiang, Gengyuan Cai, Dewu Liu, Ching Yuan Hu, Chong Wang
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
34650665
Multifunctional agents based on benzoxazolone as promising therapeutic drugs for diabetic nephropathy
点击查看 >>
Author：
Xin Zhang, Huan Chen, Yanqi Lei, Xiaonan Zhang, Long Xu, Wenchao Liu, Zhenya Fan, Zequn Ma, Zhechang Yin, Lingyun Li, Changjin Zhu, Bing Ma
IF：
6.5140
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
33588177
Neddylation inactivation affects cell cycle and apoptosis in sheep follicular granulosa cells
点击查看 >>
Author：
Xiaowei Qin, Wenqing Dang, Xiaofeng Yang, Kai Wang, Ermias Kebreab, Lihua Lyu
IF：
6.5130
Publish_to：
JOURNAL OF CELLULAR PHYSIOLOGY
PMID：
35578798
New role of gramicidin A in RIG-I-like receptors-mediated IFN signalling
点击查看 >>
Author：
Xiao Li, Xinyuan Sun, Zhongyi Yan, Zhenxiang Zhao, Zhaojun Pang, Han Yang, Xiaoxin Ji, Yi Lei, Zixiang Zhu, Xiangqian Guo, Xin Mu
IF：
6.4000
Publish_to：
IMMUNOLOGY
PMID：
36683251
Pyridoxine regulates hair follicle development via the PI3K/Akt, Wnt and Notch signalling pathways in rex rabbits
点击查看 >>
Author：
Gongyan Liu, Guangmin Cheng, Yongcui Zhang, Shuxia Gao, Haitao Sun, Liya Bai, Shu Li, Yanli Zhu, Chunyang Wang, Fuchang Li
IF：
6.3830
Publish_to：
Animal Nutrition
PMID：
34754958
Icariin attenuates perfluorooctane sulfonate-induced testicular toxicity by alleviating Sertoli cell injury and downregulating the p38MAPK/MMP9 pathway
点击查看 >>
Author：
Yan Zhang, Xiaoping Wu, Kaili Zhu, Shangyu Liu, Yuan Yang, Ding Yuan, Ting Wang, Yumin He, Yaoyan Dun, Jie Wu, Changcheng Zhang, Haixia Zhao
IF：
6.3170
Publish_to：
Food & Function
PMID：
35262540
Nanoplastics aggravate the toxicity of arsenic to AGS cells by disrupting ABC transporter and cytoskeleton
点击查看 >>
Author：
Peichun Lin, Yitao Guo, Lei He, Xiuchun Liao, Xueru Chen, Liuying He, Zifan Lu, Zhong-Ji Qian, Chunxia Zhou, Pengzhi Hong, Shengli Sun, Chengyong Li
IF：
6.2910
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
34634601
Translocator Protein Ligand Etifoxine Attenuates MPTP-Induced Neurotoxicity
点击查看 >>
Author：
Qi Tian, Xiaoxia Yang, Juan Du, Huachen Huang, Wei Liu, Peng Zhao
IF：
6.2610
Publish_to：
Frontiers in Molecular Neuroscience
PMID：
35686060
Cancer Associated Fibroblasts Promote Renal Cancer Progression Through a TDO/Kyn/AhR Dependent Signaling Pathway
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Author：
Chen Li-bo, Zhu Shun-ping, Liu Tian-pei, Zhao Heng, Chen Ping-feng, Duan You-jun, Hu Rong
IF：
6.2440
Publish_to：
Frontiers in Oncology
PMID：
33842334
Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation
点击查看 >>
Author：
Shaobin Yang, Yaqin Du, Xiaoqian Zhao, Qi Tang, Wei Su, Yuemeng Hu, Peng Yu
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
35628181
Higenamine Promotes Osteogenesis Via IQGAP1/SMAD4 Signaling Pathway and Prevents Age- and Estrogen-Dependent Bone Loss in Mice
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Author：
Hui Dong, Ronghan Liu, Ke Zou, Zhengxin Jin, Jianning Kang, Ying Zhang, Xiaodi Zhang, Zhengfang Sun, Guilian Yu, Nana Huang, Morgan Bretches, Shang-You Yang, Bin Ning
IF：
6.2000
Publish_to：
JOURNAL OF BONE AND MINERAL RESEARCH
PMID：
36907987
miR-21-5p in extracellular vesicles obtained from adipose tissue-derived stromal cells facilitates tubular epithelial cell repair in acute kidney injury
点击查看 >>
Author：
Zhixiang Bian, Xiangxiang Wang, Rui Zhu, Shunjie Chen
IF：
6.1960
Publish_to：
CYTOTHERAPY
PMID：
36244909
Prenatal EGCG consumption causes obesity and perturbs glucose homeostasis in adult mice
点击查看 >>
Author：
Kunlin Ou, Shenli Zhang, Jialin Song, Lu Fang, Siyu Xia, Jie Huang, Qin Wang, Chonggang Wang
IF：
6.1170
Publish_to：
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
PMID：
36223832
Gut microbiota disorder induces liver dysfunction in polycystic ovary syndrome rats model by regulating metabolite rosmarinic acid
点击查看 >>
Author：
Tingting Zhang, Huimin Gao, Yali Fan, Shuya Chen, Yingying Li, Ruixia Liu, Tianhe Li, Chenghong Yin
IF：
6.1000
Publish_to：
LIFE SCIENCES
PMID：
37423380
Lactobacillus rhamnosus GR-1 Alleviates Escherichia coli-Induced Inflammation via NF-κB and MAPKs Signaling in Bovine Endometrial Epithelial Cells
点击查看 >>
Author：
Liu Jiawei, Feng Xiaowei, Li Botong, Sun Yan, Jin Tianxiong, Feng Mingque, Ni Yaodi, Liu Mingchao
IF：
6.0730
Publish_to：
Frontiers in Cellular and Infection Microbiology
PMID：
35310848
Single Gold Nanostars Achieve Inherent Cascade Catalytic and Near-Infrared Photothermal Activities for Efficient Tumor Therapy
点击查看 >>
Author：
Meijun Zhao, Yuxuan Li, Yian Liu, Lintao Bai, Junjie Ma, Mei Ren, Jiahui Liu, Heyun Shen
IF：
6.0690
Publish_to：
BIOCONJUGATE CHEMISTRY
PMID：
36111663
Preparation of Novel ICT-CMC-CD59sp Drug-Loaded Microspheres and Targeting Anti-Tumor Effect on Oral Squamous Cell Carcinoma
点击查看 >>
Author：
Xiang Gao, Wanchun Wang, Meihua Gao
IF：
6.0640
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
35387305
Improving the Efficiency of Precise Genome Editing with CRISPR/Cas9 to Generate Goats Overexpressing Human Butyrylcholinesterase
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Author：
Jia-Hao Wang, Su-Jun Wu, Yan Li, Yue Zhao, Zhi-Mei Liu, Shou-Long Deng, Zheng-Xing Lian
IF：
6.0000
Publish_to：
Cells
PMID：
37508483
The safe Laccase@ZIF-8-prodrug system with GSH redox cycle for effective targeted cancer therapy with low off-target toxicity
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Author：
Yu Zhou, Chengyu Zhang, Yuefei Wang, Jiaxing Zhang, Xiaohui Yan, Shengping You, Wei Qi, Rongxin Su, Zhimin He
IF：
5.9990
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
PMID：
36215892
Rutaecarpine Attenuates Oxidative Stress-Induced Traumatic Brain Injury and Reduces Secondary Injury via the PGK1/KEAP1/NRF2 Signaling Pathway
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Author：
Min Xu, Liu Li, Hua Liu, Wei Lu, Xiaoyang Ling, Mingjie Gong
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35529443
CTI-2 Inhibits Metastasis and Epithelial-Mesenchymal Transition of Breast Cancer Cells by Modulating MAPK Signaling Pathway
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Author：
Junfeng Ke, Wenzhao Han, Fanwei Meng, Feng Guo, Yuhong Wang, Liping Wang
IF：
5.9240
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
34830111
Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles
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Author：
Xie Zheng-Yuan, Cao Heng-Wei, Wang Qing, Lu Hui, Du Wen
IF：
5.9080
Publish_to：
Journal of Cell Communication and Signaling
PMID：
36508052
Plasma Spray vs. Electrochemical Deposition: Toward a Better Osteogenic Effect of Hydroxyapatite Coatings on 3D-Printed Titanium Scaffolds
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Author：
Sun Yang, Zhang Xing, Luo Mingran, Hu Weifan, Zheng Li, Huang Ruqi, Greven Johannes, Hildebrand Frank, Yuan Feng
IF：
5.8900
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
34381765
Anti-gastric cancer activity and mechanism of natural compound “Heilaohulignan C” isolated from Kadsura coccinea
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Author：
Muhammad Daniyal, Yongbei Liu, Yupei Yang, Feng Xiao, Jialong Fan, Huanghe Yu, Yixing Qiu, Bin Liu, Wei Wang, Qin Yuhui
IF：
5.8820
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
34155704
The ethanol extract of Edgeworthia gardneri (Wall.) Meisn attenuates macrophage foam cell formation and atherogenesis in ApoE−/− mice
点击查看 >>
Author：
Tang Le, Kuang Cuifang, Shan Dan, Shi Min, Li Jiangsheng, Qiu Liang, Yu Jun
IF：
5.8460
Publish_to：
Frontiers in Cardiovascular Medicine
PMID：
36505350
Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis
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Author：
Zhang Qin, Long Jing, Li Nannan, Ma Xuelian, Zheng Lisheng
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
33776760
Exosomal circRNA RHOT1 promotes breast cancer progression by targeting miR-204-5p/ PRMT5 axis
点击查看 >>
Author：
Jiang Weihua, Yu YinPing, Ou Jianghua, Li Yongtao, Zhu Ning
IF：
5.8000
Publish_to：
Cancer Cell International
PMID：
37924099
Three-dimensional-printed collagen/chitosan/secretome derived from HUCMSCs scaffolds for efficient neural network reconstruction in canines with traumatic brain injury
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Author：
Liu Xiaoyin, Zhang Guijun, Wei Pan, Zhong Lin, Chen Yaxing, Zhang Jianyong, Chen Xuyi, Zhou Liangxue
IF：
5.7630
Publish_to：
Regenerative Biomaterials
PMID：
35855109
Cold Atmospheric Plasma Conveys Selectivity Against Hepatocellular Carcinoma Cells via Triggering EGFR(Tyr1068)-Mediated Autophagy
点击查看 >>
Author：
Danjun Wang, Jianying Zhang, Linhan Cai, Xiaofeng Dai
IF：
5.7380
Publish_to：
Frontiers in Oncology
PMID：
35860596
Clinically relevant orthotopic xenograft models of patient-derived glioblastoma in zebrafish
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Author：
Ai, Xiaolin, Ye, Zengpanpan, Xiao, Chaoxin, Zhong, Jian, Lancman, Joseph J., Chen, Xuelan, Pan, Xiangyu, Yang, Yu, Zhou, Lin, Wang, Xiang, Shi, Huashan, Zhang, Dongmei, Yao, Yuqin, Cao, Dan, Zhao, Chengjian
IF：
5.7320
Publish_to：
Disease Models & Mechanisms
PMID：
35199829
Engineering single-domain antibodies targeting Gasdermin E activation by the chemotherapeutic agent cis-diaminodichloroplatinum
点击查看 >>
Author：
Jinyi Ma, Jintao Xu, Qiuyun Gao, Yanan Sun, Yu Wang, Zhe Liu, Zhenyi Ma
IF：
5.7260
Publish_to：
Biotechnology Journal
PMID：
37204010
Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5
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Author：
Chang Zhiwei, Fu Yang, Jia Yongxu, Gao Ming, Song Lijie, Zhang Weijie, Zhao Ruihua, Qin Yanru
IF：
5.7220
Publish_to：
Cancer Cell International
PMID：
34530825
Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4+ T cells in chronic liver injury
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Author：
Yuwei Zhang, Xue Yang, Tao Bi, Xia Wu, Lu Wang, Yafeng Ren, Yangying Ou, Chengliang Xie, Kuangjie Li, Haolong Ran, Jing Wang, Fulan Zhao, Pixian Shui, Jie Qing
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
35219165
Development of tetracycline-modified nanoparticles for bone-targeted delivery of anti-tubercular drug
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Author：
Qiuzhen Liang, Pengfei Zhang, Liang Zhang, Haopeng Luan, Xinxia Li, Haibin Xiang, Shuang Jing, Xinghua Song
IF：
5.7000
Publish_to：
Frontiers in Bioengineering and Biotechnology
PMID：
37635999
Hemorrhage-Induced Sphingosine Kinase 1 Contributes to Ferroptosis-Mediated Secondary Brain Injury in Intracerebral Hemorrhage
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Author：
Diao Xiaojun, Cui Qi, Tian Ning, Zhou Zixian, Xiang Wenjing, Jiang Yanlin, Deng Jungang, Liao Hongzhan, Lin Xiaohui, Li Qinghua, Liao Rujia
IF：
5.6820
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
34993846
Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent Fashion
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Author：
Shi Ruihan, Hou Lei, Wei Li, Quan Rong, Zhou Bin, Jiang Haijun, Wang Jing, Zhu Shanshan, Song Jiangwei, Wang Dan, Liu Jue
IF：
5.6400
Publish_to：
Frontiers in Microbiology
PMID：
33679671
Antibacterial Effect of Gallic Acid in UV-C Light Treatment Against Escherichia coli O157:H7 and the Underlying Mechanism
点击查看 >>
Author：
Zhu Yuzhang, Lin Kun, Zhang Xuan, Ma Huawei, Yang Li, Wei Li, Yang Lifang, Jiang Mingguo
IF：
5.6000
Publish_to：
Food and Bioprocess Technology
PMID：
Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy
点击查看 >>
Author：
郭帅
IF：
5.5740
Publish_to：
PMID：
32097750
Isolation, Characterization, and Application of Clostridium sporogenes F39 to Degrade Zearalenone under Anaerobic Conditions
点击查看 >>
Author：
Congning Zhai, Yangguang Yu, Jun Han, Junqiang Hu, Dan He, Hongyin Zhang, Jianrong Shi, Sherif Ramzy Mohamed, Dawood H. Dawood, Gang Wang, Jianhong Xu
IF：
5.5610
Publish_to：
Foods
PMID：
35563917
N6-methyladenosine RNA modification promotes Severe Fever with Thrombocytopenia Syndrome Virus infection
点击查看 >>
Author：
Zhiqiang Chen, Jinyu Zhang, Jun Wang, Hao Tong, Wen Pan, Feng Ma, Qihan Wu, Jianfeng Dai
IF：
5.5000
Publish_to：
PLoS Pathogens
PMID：
39585899
Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling Pathway
点击查看 >>
Author：
Bin Yan, Canjun Zeng, Yuhui Chen, Minjun Huang, Na Yao, Jie Zhang, Bo Yan, Jiajun Tang, Liang Wang, Zhongmin Zhang
IF：
5.4430
Publish_to：
Stem Cells International
PMID：
34912459
Buyang Huanwu Decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway
点击查看 >>
Author：
Guoyong Zhang, Xin Han, Tong Xu, Min Liu, Guanghong Chen, Lingpeng Xie, Honglin Xu, Yue Hua, Mingjie Pang, Changlei Hu, Yuting Wu, Bin Liu, Yingchun Zhou
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
37949329
Quercetin improves atrial fibrillation through inhibiting TGF-β/Smads pathway via promoting MiR-135b expression
点击查看 >>
Author：
Hongtao Wang, Wei Jiang, Yanchao Hu, Zhaofei Wan, Hongyuan Bai, Qiang Yang, Qiangsun Zheng
IF：
5.3400
Publish_to：
PHYTOMEDICINE
PMID：
34656066
Dihydromyricetin resists inflammation-induced muscle atrophy via ryanodine receptor-CaMKK-AMPK signal pathway
点击查看 >>
Author：
Lianjie Hou, Fangyi Jiang, Bo Huang, Weijie Zheng, Yufei Jiang, Gengyuan Cai, Dewu Liu, Ching Yuan Hu, Chong Wang
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
34676967
A novel L-shaped ortho-quinone analog suppresses glioblastoma progression by targeting acceleration of AR degradation and regulating PI3K/AKT pathway
点击查看 >>
Author：
Tao Zhang, Weidong Pan, Xin Tan, Jia Yu, Sha Cheng, Shinan Wei, Kuan Fan, Lu Wang, Heng Luo, Xiao Hu
IF：
5.3000
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
38944395
MRCKα is a novel regulator of prolactin-induced lactogenesis in bovine mammary epithelial cells
点击查看 >>
Author：
Fang Wang, Jürgen van Baal, Lu Ma, Xuejun Gao, Jan Dijkstra, Dengpan Bu
IF：
5.2850
Publish_to：
Animal Nutrition
PMID：
35891685
Opposite Regulatory Effects of Immobilized Cations on the Folding Vs. Assembly of Melittin
点击查看 >>
Author：
Lanlan Yu, Zhun Deng, Wenbo Zhang, Shuli Liu, Feiyi Zhang, Jianjian Zhou, Chunhua Ma, Chenxuan Wang
IF：
5.2210
Publish_to：
Frontiers in Chemistry
PMID：
34178946
Antitumor property of WE43 magnesium alloy subjected to anodic oxidation plus heat treatment
点击查看 >>
Author：
Xugang Lu, Rui Zuo, Jun Chen, Yi Hu, Changsheng Wei, Yuqiang Guo, Shibing Xiong, Simeng Wang, Siqi Zhang, Yifan Cui, Meiju Xie, Bangcheng Yang
IF：
5.2000
Publish_to：
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
PMID：
Acacetin attenuates diabetes-induced cardiomyopathy by inhibiting oxidative stress and energy metabolism via PPAR-α/AMPK pathway
点击查看 >>
Author：
Fei Song, Yi-Jie Mao, Yu Hu, Shan-Shan Zhao, Ruiying Wang, Wei-Yin Wu, Gui-Rong Li, Yan Wang, Gang Li
IF：
5.1950
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
35341782
Combination of chondrocytes and chondrons improves extracellular matrix production to promote the repairs of defective knee cartilage in rabbits
点击查看 >>
Author：
Wangping Duan, Yu Zhao, Xiaochun Ren, Ruipeng Zhao, Qi Li, Zhenwei Sun, Wenjie Song, Yanfei Yang, Pengcui Li, Xiaochun Wei
IF：
5.1910
Publish_to：
Journal of Orthopaedic Translation
PMID：
33717981
Extracellular Vesicles Derived from Lung Cancer Cells Induce Transformation of Normal Fibroblasts into Lung Cancer-Associated Fibroblasts and Promote Metastasis of Lung Cancer by Delivering lncRNA HOTAIR
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Author：
Xiaoxuan Zhang, Yan Zhang, Xin Qiu, Jing Cai, Zhenzhou Yang, Fangzhou Song
IF：
5.1310
Publish_to：
Stem Cells International
PMID：
36267242
Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission
点击查看 >>
Author：
Heng Yin, Xinglai Li, Chengbi Wang, Xiaocong Li, Jingbo Liu
IF：
5.1000
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
38552765
Metformin enhances the osteogenesis and angiogenesis of human umbilical cord mesenchymal stem cells for tissue regeneration engineering
点击查看 >>
Author：
Tong Lei, Shiwen Deng, Peng Chen, Zhuangzhuang Xiao, Shanglin Cai, Zhongci Hang, Yanjie Yang, Xiaoshuang Zhang, Quanhai Li, Hongwu Du
IF：
5.0850
Publish_to：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
PMID：
34551339
Immune Responses to Orally Administered Recombinant Lactococcus lactis Expressing Multi-Epitope Proteins Targeting M Cells of Foot-and-Mouth Disease Virus
点击查看 >>
Author：
Fudong Zhang, Zhongwang Zhang, Xian Li, Jiahao Li, Jianliang Lv, Zhongyuan Ma, Li Pan
IF：
5.0480
Publish_to：
Viruses-Basel
PMID：
34696469
Multifunctional Liposomes Co-Modified with Ginsenoside Compound K and Hyaluronic Acid for Tumor-Targeted Therapy
点击查看 >>
Author：
Xiaoyan You, Hui Liu, Yue Chen, Guoping Zhao
IF：
5.0000
Publish_to：
Polymers
PMID：
38337294
Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells
点击查看 >>
Author：
Zhou Yuan, Chen Li, Ding Deping, Li Ziheng, Cheng Li, You Qiuyun, Zhang Shunbo
IF：
4.9960
Publish_to：
Scientific Reports
PMID：
35545654
Lactucin, a Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway
点击查看 >>
Author：
Khandaker Md Sharif Uddin Imam, Yu Tian, Fengjiao Xin, Yingying Xie, Boting Wen
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36364182
Cypate-loaded hollow mesoporous Prussian blue nanoparticle/hydrogel system for efficient photodynamic therapy/photothermal therapy dual-modal antibacterial therapy
点击查看 >>
Author：
Zheng Xing, Bingyu Dong, Xiaoxiao Zhang, Lin Qiu, Pengju Jiang, Yang Xuan, Xinye Ni, Hongbin Xu, Jianhao Wang
IF：
4.9000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
37728144
Network Pharmacology and Molecular Docking Reveal the Mechanism of Isodon ternifolius (D. Don) Kudo Against Liver Fibrosis
点击查看 >>
Author：
Jiasheng Deng, Le Qin, Zhipin Zhou
IF：
4.8000
Publish_to：
Drug Design Development and Therapy
PMID：
37576085
Oral Codelivery of WR-1065 Using Curcumin-Linked ROS-Sensitive Nanoparticles for Synergistic Radioprotection
点击查看 >>
Author：
Yahong Liu, Longfei Miao, Yuying Guo, Renbin Yuan, Xuejiao Li, Xinxin Wang, Xiaona Lin, Hongqi Tian
IF：
4.7490
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
33825438
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4
点击查看 >>
Author：
Jiwei Wang, Xi Ouyang, Zhiyong Zhou, Shengxun Mao, Xiaoqiang Niu, Huizi Li, Wei Xu, Yi Song, Jiaqing Cao, Bin Lai
IF：
4.7390
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
PMID：
34670117
Antiviral Activity of Ailanthone from Ailanthus altissima on the Rice Stripe Virus
点击查看 >>
Author：
Qingwei Tan, Jianxuan Zhu, Yuanyuan Ju, Xinlin Chi, Tangdan Cao, Luping Zheng, Qijian Chen
IF：
4.7000
Publish_to：
Viruses-Basel
PMID：
38257773
Structural Characterization and Immunobiological Activity of Polysaccharides from Astragalus Oyster Mushroom
点击查看 >>
Author：
Qiuxia Meng, Yu Niu, Rongrong Wang, Wei Niu, Lizhen Zhang
IF：
4.6000
Publish_to：
MOLECULES
PMID：
37446941
Long non-coding RNA LIFR-AS1 suppressed the proliferation, angiogenesis, migration and invasion of papillary thyroid cancer cells via the miR-31-5p/SIDT2 axis
点击查看 >>
Author：
Dan Yi, Dongxin Zhang, Jie He
IF：
4.5340
Publish_to：
CELL CYCLE
PMID：
34781815
Effect of Platelet-Rich Plasma Addition on the Chemical Properties and Biological Activity of Calcium Sulfate Hemihydrate Bone Cement
点击查看 >>
Author：
Jingyu Liu, Yifan Wang, Yanqin Liang, Shengli Zhu, Hui Jiang, Shuilin Wu, Xiang Ge, Zhaoyang Li
IF：
4.5000
Publish_to：
Biomimetics
PMID：
37366857
Impact of Amarogentin on Gastric Carcinoma Cell Multiplication, Apoptosis and Migration via circKIF4A/miR-152-3p
点击查看 >>
Author：
Zhi Tan, Weining Wang, Jin Peng, Zhen Zhou, Jia Pan, Aiming Peng, Hui Cao, Wenling Fan
IF：
4.4930
Publish_to：
Journal of Immunology Research
PMID：
35747689
METTL3 inhibition ameliorates liver damage in mouse with hepatitis B virus-associated acute-on-chronic liver failure by regulating miR-146a-5p maturation
点击查看 >>
Author：
Da Cheng, Cichun Wu, Ying Li, Yao Liu, Juan Mo, Lei Fu, Shifang Peng
IF：
4.4900
Publish_to：
Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
PMID：
34968770
Akkermansia muciniphila administration exacerbated the development of colitis-associated colorectal cancer in mice
点击查看 >>
Author：
Fei Wang, Kuntai Cai, Qiuxiang Xiao, Lihua He, Lu Xie, Zhiping Liu
IF：
4.4780
Publish_to：
Journal of Cancer
PMID：
34976176
LINC01224 accelerates malignant transformation via MiR-193a-5p/CDK8 axis in gastric cancer
点击查看 >>
Author：
Hui Sun, Jihong Yan, Guangyu Tian, Xiaojun Chen, Wenbo Song
IF：
4.4520
Publish_to：
Cancer Medicine
PMID：
33655711
Mycoplasma suis Alpha-Enolase Subunit Vaccine Induces an Immune Response in Experimental Animals
点击查看 >>
Author：
Shujiang Xue, Kangseok Seo, Miaosen Yang, Chengdu Cui, Meng Yang, Siyu Xiang, Zongbin Yan, Shengjun Wu, Jincheng Han, Xiaoyang Yu, Yunxiao Li, Xin Jin
IF：
4.4220
Publish_to：
Vaccines
PMID：
34960252
Development and Optimization of Chitosan Nanoparticle-Based Intranasal Vaccine Carrier
点击查看 >>
Author：
Xiaoyi Gao, Nan Liu, Zengming Wang, Jing Gao, Hui Zhang, Meng Li, Yimeng Du, Xiang Gao, Aiping Zheng
IF：
4.4120
Publish_to：
MOLECULES
PMID：
35011436
Near-infrared dual-response fluorescent probe for detection of N2H4 and intracellular viscosity changes in biological samples and various water samples
点击查看 >>
Author：
Chen Xu, Yukun Zhang, Mingguang Ren, Keyin Liu, Qin Wu, Chunling Zhang, Fangong Kong
IF：
4.4000
Publish_to：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
PMID：
38522378
Maf1 mitigates sevoflurane-induced microglial inflammatory damage and attenuates microglia-mediated neurotoxicity in HT-22 cells by activating the AMPK/Nrf2 signaling
点击查看 >>
Author：
Yunyi Dai, Mingguang Yan, Juan Wan, Tao Xiao
IF：
4.3980
Publish_to：
NEUROTOXICOLOGY
PMID：
35430185
Gallium (Ga) strontium (Sr) layered double hydroxide composite coating on titanium substrates for enhanced osteogenic and antibacterial abilities
点击查看 >>
Author：
陶白龙
IF：
4.3960
Publish_to：
PMID：
34323363
Xuanfei Baidu Decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6/STAT3 signaling pathway
点击查看 >>
Author：
Yuying Wang, Xiaoqing Sang, Rui Shao, Honglin Qin, Xuanhao Chen, Zhifeng Xue, Lin Li, Yu Wang, Yan Zhu, Yanxu Chang, Xiumei Gao, Boli Zhang, Han Zhang, Jian Yang
IF：
4.3600
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
34606948
Component Identification of Phenolic Acids in Cell Suspension Cultures of Saussureainvolucrata and Its Mechanism of Anti-Hepatoma Revealed by TMT Quantitative Proteomics
点击查看 >>
Author：
Junpeng Gao, Yi Wang, Bo Lyu, Jian Chen, Guang Chen
IF：
4.3500
Publish_to：
Foods
PMID：
34681515
KIT-SNAP-tag/cell membrane chromatography model coupled with liquid chromatography–mass spectrometry for anti-GIST compound screening from Evodia rutaecarpa
点击查看 >>
Author：
Feng Jingting, Jiang Yuhan, Liu Sihan, Deng Linge, Lv Yanni, Chen Nanzheng, Han Shengli
IF：
4.3000
Publish_to：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
PMID：
38231254
MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2
点击查看 >>
Author：
Meng Sun, Min Guo, Guijin Ma, Nan Zhang, Feifei Pan, Xiaoling Fan, Rui Wang
IF：
4.2190
Publish_to：
TOXICOLOGY AND APPLIED PHARMACOLOGY
PMID：
34217758
Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation
点击查看 >>
Author：
Qiqi Zhang, Qing Liu, Shutao Zheng, Tao Liu, Lifei Yang, Xiujuan Han, Xiaomei Lu
IF：
4.2070
Publish_to：
Journal of Cancer
PMID：
34234853
Bioinformatics and experimental validation of an AURKA/TPX2 axis as a potential target in esophageal squamous cell carcinoma
点击查看 >>
Author：
Ruijuan Du, Kai Li, Zijun Zhou, Yunlong Huang, Kelei Guo, Hui Zhang, Zhiguo Chen, Xulin Zhao, Li Han, Hua Bian
IF：
4.2000
Publish_to：
ONCOLOGY REPORTS
PMID：
37083097
GATA2 promotes oxidative stress to aggravate renal ischemia-reperfusion injury by up-regulating Redd1
点击查看 >>
Author：
Dan Huang, Dan Chen, Taotao Hu, Hongqing Liang
IF：
4.1740
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
36444820
Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells
点击查看 >>
Author：
Wenjing Zhang, Cui Wang, Xiaomei Hu, Yanzhen Lian, Caili Ding, Liang Ming
IF：
4.1360
Publish_to：
ONCOLOGY REPORTS
PMID：
35191522
Protective effects of MNQ against Lipopolysaccharide-induced inflammatory damage in bovine ovarian follicular granulosa cells in Vitro
点击查看 >>
Author：
Xiaofeng Yang, Tong Guo, Zhangsheng Du, Xiaowei Qin, Kai Wang, Ermias Kebreab, Dong Wang, Lihua Lyu
IF：
4.1000
Publish_to：
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
PMID：
36813140
Fraxetin attenuates ferroptosis in myocardial infarction via AKT/Nrf2/HO-1 signaling
点击查看 >>
Author：
Yifei Xu, Haiyan Lin, Huan Wang, Jie Pang, Ying Zhou
IF：
4.0600
Publish_to：
American Journal of Translational Research
PMID：
34650699
Hypoxia pretreatment improves the therapeutic potential of bone marrow mesenchymal stem cells in hindlimb ischemia via upregulation of NRG-1
点击查看 >>
Author：
Peng Xitao, Liang Bing, Wang Haisheng, Hou Jingyuan, Yuan Qidong
IF：
4.0510
Publish_to：
CELL AND TISSUE RESEARCH
PMID：
35091805
Astragaloside IV Improves Tibial Defect in Rats and Promotes Proliferation and Osteogenic Differentiation of hBMSCs through MiR-124-3p.1/STAT3 Axis
点击查看 >>
Author：
Yujing Cao, Qiuxia Lv, Yang Li
IF：
4.0500
Publish_to：
JOURNAL OF NATURAL PRODUCTS
PMID：
33464097
Enzymatic synthesis of vitexin glycosides and their activity
点击查看 >>
Author：
Tingting Xu, Ziyun Fan, Junqiao Lou, Qi Du, Yue Kong, Yujia Lu, Xueming Wu
IF：
4.0360
Publish_to：
RSC Advances
PMID：
36093238
Long noncoding RNA SNHG6 promotes the malignant phenotypes of ovarian cancer cells via miR-543/YAP1 pathway
点击查看 >>
Author：
Mengya Su, Ping Huang, Qian Li
IF：
4.0000
Publish_to：
Heliyon
PMID：
37234669
Long noncoding RNA urothelial carcinoma associated 1 protects human placental vascular endothelial cells from hypoxia-induced damage by regulating the miR-197-3p/histone deacetylase-2 axis in patients with pregnancy-induced hypertension.
点击查看 >>
Author：
Jie Li, Yiling Lu, Ying Wang, Xiaoyu Wang, Xinyi Kang, Weichun Tang, Liping Chen
IF：
3.9400
Publish_to：
American Journal of Translational Research
PMID：
36247238
Gradient nanostructured titanium stimulates cell responses in vitro and enhances osseointegration in vivo
点击查看 >>
Author：
Nan-Jue Cao, Yu-He Zhu, Fei Gao, Chen Liang, Zhen-Bo Wang, Yue Zhang, Chun-Ping Hao, Wei Wang
IF：
3.9320
Publish_to：
Annals of Translational Medicine
PMID：
33987229
Estrogen promotes Epithelial ovarian cancer cells proliferation via down-regulating expression and activating phosphorylation of PTEN
点击查看 >>
Author：
Xiuwen Li, Chunlei Miao, Lin Wang, Mengyan Liu, Huanchao Chang, Bo Tian, Di Wang
IF：
3.9000
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
37276925
Total synthesis of (±) commiphoranes C–D and their epimers
点击查看 >>
Author：
Xiaoyu Liu, Haidong Deng, Yingjun Jiang, Yang Cao, Zhe Wang, Xiaozhen Jiao, Ping Xie
IF：
3.8900
Publish_to：
ORGANIC & BIOMOLECULAR CHEMISTRY
PMID：
35195145
Enhancing osteogenic potential of hDPSCs by resveratrol through reducing oxidative stress via the Sirt1/Nrf2 pathway
点击查看 >>
Author：
Jingying Zhang, Rui Li, Kenny Man, Xuebin B. Yang
IF：
3.8890
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
35188840
Enzyme-instructed supramolecular assemblies promote intracellular boron accumulation for boron neutron capture therapy
点击查看 >>
Author：
Qingxin Yao, Chengling Wu, Jiali Chen, Yan Zhao, Yuan Gao
IF：
3.8740
Publish_to：
NANOTECHNOLOGY
PMID：
34280913
Involvement of elevated ASF1B in the poor prognosis and tumorigenesis in pancreatic cancer
点击查看 >>
Author：
Wang Kun, Hao Zhiqiang, Fu Xibo, Li Wenxin, Jiao Ao, Hua Xiangdong
IF：
3.8420
Publish_to：
MOLECULAR AND CELLULAR BIOCHEMISTRY
PMID：
35362843
MiR-98 Protects Nucleus Pulposus Cells against Apoptosis by Targeting TRAIL in Cervical Intervertebral Disc Degeneration
点击查看 >>
Author：
Shimin Xu, Yuezhong Li, Junshan Zhang, Zhiwei Li, Yanping Xing
IF：
3.8220
Publish_to：
Journal of Healthcare Engineering
PMID：
35126933
Exposure to enriched environment ameliorated chronic unpredictable mild stress-induced depression-like symptoms in rats via regulating the miR-92a-3p/kruppel-like factor 2 (KLF2) pathway
点击查看 >>
Author：
Xiao Ji, Zhenwu Zhao
IF：
3.8000
Publish_to：
BRAIN RESEARCH BULLETIN
PMID：
36638871
The combination of chronic stress and smoke exacerbated depression-like changes and lung cancer factor expression in A/J mice: Involve inflammation and BDNF dysfunction
点击查看 >>
Author：
Bai-Ping Liu, Cai Zhang, Yong-Ping Zhang, Kang-Wei Li, Cai Song
IF：
3.7520
Publish_to：
PLoS One
PMID：
36417428
Biocompatible Nano-Hydroxyapatites Regulate Macrophage Polarization
点击查看 >>
Author：
Da-Wang Zhao, Xin-Cheng Fan, Yi-Xiang Zhao, Wei Zhao, Yuan-Qiang Zhang, Ren-Hua Zhang, Lei Cheng
IF：
3.7480
Publish_to：
Materials
PMID：
36234325
Antifungal Activity of NP20 Derived from Amphioxus Midkine/Pleiotrophin Homolog Against Aspergillus niger and Aspergillus fumigatus
点击查看 >>
Author：
Li Zhi, Shen Fangwang, Song Lili, Zhang Shicui
IF：
3.7270
Publish_to：
MARINE BIOTECHNOLOGY
PMID：
35610324
LINC01426 aggravates the malignant progression of glioma through miR-661/Mdm2 axis
点击查看 >>
Author：
Bo Shu, Hongchuan Gan, Cheng Wang, Chunan Cao, Hui Tong, Dan Liang
IF：
3.7150
Publish_to：
BRAIN RESEARCH BULLETIN
PMID：
35772605
Pterostilbene upregulates MICA/B via the PI3K/AKT signaling pathway to enhance the capability of natural killer cells to kill cervical cancer cells
点击查看 >>
Author：
Zuoping Li, Jiaru Zhang, Shiwan You, Jing Zhang, Yuling Zhang, Zubair Akram, Shiguo Sun
IF：
3.7000
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
38296018
Preparation of Black pepper (Piper nigrum L.) essential oil nanoparticles and its antitumor activity on triple negative breast cancer in vitro
点击查看 >>
Author：
Mengying Zhang, Beibei Qiu, Mengjia Sun, Yunfei Wang, Meijiao Wei, Yanling Gong, Meixing Yan
IF：
3.6540
Publish_to：
JOURNAL OF FOOD BIOCHEMISTRY
PMID：
36121189
CircCRIM1 mediates proliferation, migration, and invasion of trophoblast cell through regulating miR-942-5p/IL1RAP axis
点击查看 >>
Author：
Fen Yu, Jie Xing, Lingyun Li, Mi Xiang
IF：
3.6000
Publish_to：
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
PMID：
37382169
Hydrogen Alleviates Neuronal Injury and Neuroinflammation Induced by Microglial Activation via the Nuclear Factor Erythroid 2-related Factor 2 Pathway in Sepsis-associated Encephalopathy
点击查看 >>
Author：
Hongguang Chen, Beibei Dong, Yuan Shi, Yonghao Yu, Keliang Xie
IF：
3.5900
Publish_to：
NEUROSCIENCE
PMID：
33992722
A novel C-type lectin from Crassostrea gigas involved in the innate defense against Vibrio alginolyticus
点击查看 >>
Author：
Honglin Chen, Xiaohui Cai, Hangna Qiu, Jing Fang, Xinzhong Wu
IF：
3.5750
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
34126346
TET-mediated DNA demethylation plays an important role in arsenic-induced HBE cells oxidative stress via regulating promoter methylation of OGG1 and GSTP1
点击查看 >>
Author：
Qingling Wang, Wenjuan Wang, Aihau Zhang
IF：
3.5000
Publish_to：
TOXICOLOGY IN VITRO
PMID：
33388378
Aporphine and amide alkaloids from Illigera parviflora
点击查看 >>
Author：
Juan-Juan Xu, Yue-Ping Yin, Wei Wei, Qin-Gang Tan
IF：
3.4000
Publish_to：
FITOTERAPIA
PMID：
37939737
Occurrence of disinfectant-resistant bacteria in a fresh-cut vegetables processing facility and their role in protecting Salmonella enteritidis
点击查看 >>
Author：
Jing-Guo Xu, Jiao Meng, Wen-Jing Bao, Jia-Mu Kang, Jing-Yu Chen, Bei-Zhong Han
IF：
3.3610
Publish_to：
RSC Advances
PMID：
35423506
Extracellular vesicles from human umbilical cord mesenchymal stem cells reduce lipopolysaccharide-induced spinal cord injury neuronal apoptosis by mediating miR-29b-3p/PTEN
点击查看 >>
Author：
Xiao Xiao, Weiwei Li, Zhenchao Xu, Zhicheng Sun, Hongru Ye, Yunqi Wu, Yilu Zhang, Liqiong Xie, Dingyu Jiang, Runze Jia, Xiyang Wang
IF：
3.3420
Publish_to：
CONNECTIVE TISSUE RESEARCH
PMID：
35603476
LncRNA ABHD11-AS1 promotes tumor progression in papillary thyroid carcinoma by regulating EPS15L1/EGFR signaling pathway
点击查看 >>
Author：
Lu H., Zhu C., Chen Y., Ruan Y., Fan L., Chen Q., Wei Q.
IF：
3.3400
Publish_to：
Clinical & Translational Oncology
PMID：
35098448
Effects of hCG on DA neuronal death of Parkinson's disease
点击查看 >>
Author：
Shi-min Wang, Qin Wang, Li-yan Ye, Shao-xia Chen, Liang Tao, Zhao-shou Yang
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
35689841
Insertion of exogenous genes within the ORF1b coding region of porcine astrovirus
点击查看 >>
Author：
Teng Liu, Yijie Liao, Yanjie Du, Qinting Dong, Wenchao Zhang, Chengpeng Qiao, Ying Chen, Kang Ouyang, Zuzhang Wei, Yifeng Qin, Weijian Huang
IF：
3.3000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
36812864
Mycoplasmas bovis P48 induces apoptosis in EBL cells via an endoplasmic reticulum stress-dependent signaling pathway
点击查看 >>
Author：
Xiaochun Wu, Shengying Zhang, Cuiqin Long, Zhen An, Xiaoyong Xing, Fengqin Wen, Shijun Bao
IF：
3.2930
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
33676093
Febuxostat ameliorates APAP-induced acute liver injury by activating Keap1/Nrf2 and inhibiting TLR4/NF-κB p65 pathways
点击查看 >>
Author：
Jinhong Tian, Shuaishuai Zhang, Lu Li, Xueman Lin, Yongmei Li, Kunlu Zhao, Fengxin Zheng, Yongjun Chen, Yang Yang, Ting Wu, Jianxin Pang
IF：
3.2000
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
PMID：
38031247
Antiatherosclerotic effects of corilagin via suppression of the LOX-1/MyD88/NF-κB signaling pathway in vivo and in vitro
点击查看 >>
Author：
He Bo, Chen Deyun, Zhang Xiaochao, Yang Renhua, Yang Yuan, Chen Peng, Shen Zhiqiang
IF：
3.1920
Publish_to：
Journal of Natural Medicines
PMID：
35064897
Mast cell-derived exosomal miR-181a-5p modulated trophoblast cell viability, migration, and invasion via YY1/MMP-9 axis
点击查看 >>
Author：
Yinfen Wang, Aner Chen
IF：
3.1240
Publish_to：
JOURNAL OF CLINICAL LABORATORY ANALYSIS
PMID：
35698293
Astragalin Retards Atherosclerosis by Promoting Cholesterol Efflux and Inhibiting the Inflammatory Response via Upregulating ABCA1 and ABCG1 Expression in Macrophages
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Author：
Zhao Zhen-Wang, Zhang Min, Wang Gang, Zou Jin, Gao Jia-Hui, Zhou Li, Wan Xiang-Jun, Zhang Da-Wei, Yu Xiao-Hua, Tang Chao-Ke
IF：
3.1050
Publish_to：
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
PMID：
33165140
Saikosaponin A triggers cell ferroptosis in hepatocellular carcinoma by inducing endoplasmic reticulum stress-stimulated ATF3 expression
点击查看 >>
Author：
Tian Lan, Wen Wang, Xi-xi Zeng, Yu-hua Tong, Zhu-jun Mao, Si-wei Wang
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
37393639
miR-34a-5p inhibits the malignant progression of KSHV-infected SH-SY5Y cells by targeting c-fos
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Author：
Shuyuan Wu, Zhaofu Wu, Huiling Xu, Jinli Zhang, Wenyi Gu, Xiaohua Tan, Zemin Pan, Dongdong Cao, Dongmei Li, Lei Yang, Dongmei Li, Yuanming Pan
IF：
3.0610
Publish_to：
PeerJ
PMID：
35444864
Ellagic acid inhibits the formation of hypertrophic scars by suppressing TGF-β/Smad signaling pathway activity
点击查看 >>
Author：
Zun-jiang Zhao, De-jin Wu, Da-lun Lv, Bao-de Zhang, Lei Chen, Yin-qiao Sun
IF：
3.0000
Publish_to：
Chemical Biology & Drug Design
PMID：
37386691
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis
点击查看 >>
Author：
Zhen Jia, Jia Liu, Jing Wang
IF：
2.9960
Publish_to：
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
PMID：
36278814
HSPB1 overexpression improves hypoxic-ischemic brain damage by attenuating ferroptosis in rats through promoting G6PD expression
点击查看 >>
Author：
Yi Dai, Lan Hu
IF：
2.9740
Publish_to：
JOURNAL OF NEUROPHYSIOLOGY
PMID：
36321738
Artesunate combined with verteporfin inhibits uveal melanoma by regulation of the MALAT1/yes‑associated protein signaling pathway
点击查看 >>
Author：
Xudong Jiu, Yang Liu, Jin Wen
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
34188699
Tanshinone IIA regulates microRNA‑125b/foxp3/caspase‑1 signaling and inhibits cell viability of nasopharyngeal carcinoma
点击查看 >>
Author：
Youhu Wang, Wenyao Jin, Junbo Wang
IF：
2.9520
Publish_to：
Molecular Medicine Reports
PMID：
33760137
Cinnamaldehyde Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating TLR4/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
点击查看 >>
Author：
Xiaofen Tan, Yifan Wen, Zhijun Han, Xuyang Su, Jing Peng, Feng Chen, Yadong Wang, Tianming Wang, Changzhong Wang, Kelong Ma
IF：
2.9000
Publish_to：
CHEMISTRY & BIODIVERSITY
PMID：
36653304
Hydroxysafflor yellow A protects against ulcerative colitis via suppressing TLR4/NF-κB signaling pathway
点击查看 >>
Author：
Zhibing Feng, Ping Zhou, Xiao Wu, Junbiao Zhang, Min Zhang
IF：
2.8730
Publish_to：
Chemical Biology & Drug Design
PMID：
35319164
Hes1 Controls Proliferation and Apoptosis in Chronic Lymphoblastic Leukemia Cells by Modulating PTEN Expression
点击查看 >>
Author：
Zhang Qikai, Zhu Zongsi, Guan Jiaqiang, Hu Yingying, Zhou Wenjin, Ye Wanchun, Lin Bijing, Weng Shanshan, Chen Yuemiao, Zheng Cuiping
IF：
2.8600
Publish_to：
MOLECULAR BIOTECHNOLOGY
PMID：
35704163
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells
点击查看 >>
Author：
Li WEI, Wei MA, Hui CAI, Shao Peng PENG, Huan Bing TIAN, Ju Fang WANG, Lan GAO, Jin Peng HE
IF：
2.8310
Publish_to：
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
PMID：
35676813
MNQ derivative D21 protects against LPS-induced inflammatory damage in bovine ovarian follicular GCs in vitro via the steroid biosynthesis signaling pathway
点击查看 >>
Author：
Xiaofeng Yang, Xiaowei Qin, Kai Wang, Ermias Kebreab, Lihua Lyu
IF：
2.8000
Publish_to：
THERIOGENOLOGY
PMID：
37210939
mTORC1 is a key regulator that mediates OGD‑ and TGFβ1‑induced myofibroblast transformation and chondroitin‑4‑sulfate expression in cardiac fibroblasts
点击查看 >>
Author：
Chao Li, Zheng Zhang, Yu Peng, Yanying Zhang, Wanrong Kang, Yingdong Li, Yang Hai
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
35601064
Two Olean-27-carboxylic Acid-Type Triterpenoids as Chemical Markers Isolated from Saxifraga umbellulata
点击查看 >>
Author：
Wei Jiang, Ren Wu, Gang Ren, Yongwei Qiu, Xiaolang Du, Zejing Mu, Ting Tan, Shanshan Li, Bo Li, Wanzhi Li, Yaxin Hu, Qi Zhang, Rongrui Wei, Guoyue Zhong
IF：
2.7450
Publish_to：
CHEMISTRY & BIODIVERSITY
PMID：
35199932
MEK1/2 inhibitors induce class I alcohol dehydrogenase (ADH1) expression by regulating farnesoid X receptor in hepatic cell lines and C57BL/6J mouse
点击查看 >>
Author：
Wang Xiaolin, Yang Yanfang, Chen Yuanli, Duan Yajun, Han Jihong, Yang Xiaoxiao
IF：
2.7420
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
35338439
Anti-inflammatory effects of paeoniflorin caused by regulation of the hif1a/miR-210/caspase1/GSDMD signaling pathway in astrocytes: a novel strategy for hypoxia-induced brain injury in rats
点击查看 >>
Author：
Zhenxiu Jiang, Jun Chen, Jiangjun Chen, Zelin Lei, Hailin Chen, Jiqiang Wu, Xue Bai, Pingping Wanyan, Qin Yu
IF：
2.7300
Publish_to：
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
PMID：
34114917
Cell line derived from muscle of Gymnocypris przewalskii, a species of Schizothoracinae in Qinghai Lake, Qinghai–Tibet Plateau
点击查看 >>
Author：
Wei Fulei, Hua Qiang, Liang Jian, Yue Miao, Xu Dingfan, Tian Wengen, Yu Luxian, Feng Zhaohui
IF：
2.7230
Publish_to：
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
PMID：
36287296
The recombinant BMP-2 loaded silk fibroin microspheres improved the bone phenotype of mild osteogenesis imperfecta mice
点击查看 >>
Author：
Ting Fu, Yi Liu, Zihan Wang, Yaqing Jing, Yuxia Zhao, Chenyi Shao, Zhe Lv, Guang Li
IF：
2.7000
Publish_to：
PeerJ
PMID：
37927786
Jiawei Yanghe Decoction Regulates Bone-Lipid Balance through the BMP-SMAD Signaling Pathway to Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells
点击查看 >>
Author：
Yunfeng Luo, Hanting Xia, Jiacai Wang, Qian Hu, Yinghua Luo, Jiangyuan Liu, Zhijun Yang, Wei Li, Hongyu Wang, Fuwei Li, Zhaochong Mao, Wenlong Yang, Fengyun Yang
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
35769158
Ferulic Acid Alleviates Oxidative Stress-Induced Cardiomyocyte Injury by the Regulation of miR-499-5p/p21 Signal Cascade
点击查看 >>
Author：
Shenghui Sun, Yang Ruan, Mingjing Yan, Kun Xu, Yao Yang, Tao Shen, Zening Jin
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
34917156
Ginsenoside Rg1 Reduces Cardiotoxicity While Increases Cardiotonic Effect of Aconitine in vitro
点击查看 >>
Author：
Xu Xin, Xie Xiao-fang, Dong Yan-hong, Zhang Hui-qiong, Peng Cheng
IF：
2.6260
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
35723815
Circ_0007351 Exerts an Oncogenic Role In Colorectal Cancer Depending on the Modulation of the miR-5195-3p/GPRC5A Cascade
点击查看 >>
Author：
He Aijun, Liao Fangxin, Lin Xiaohui
IF：
2.6000
Publish_to：
MOLECULAR BIOTECHNOLOGY
PMID：
38386274
Long non-coding RNA CNALPTC1 promotes gastric cancer progression by regulating the miR-6788-5p/PAK1 pathway
点击查看 >>
Author：
Fang Li, Bibo Tan, Zihao Chen, Qun Zhao, Shi Li, Pingan Ding, Chang Liu, Xiaoxiao Wang, Xiaoya Li, Yong Li
IF：
2.5870
Publish_to：
Journal of Gastrointestinal Oncology
PMID：
36636079
Ultrasound microbubble-mediated delivery of ANLN silencing-repressed EZH2 expression alleviates cervical cancer progression
点击查看 >>
Author：
Yanyan Pan, Min Wei, Ting Gong
IF：
2.5860
Publish_to：
TISSUE & CELL
PMID：
35679682
Establishment of a cell line derived from the gills of Gymnocypris przewalskii, an endemic Schizothoracine fish from Qinghai Lake of Tibet Plateau
点击查看 >>
Author：
Fulei Wei, Jian Liang, Miao Yue, Wengen Tian, Luxian Yu, Zhaohui Feng, Qiang Hua
IF：
2.5040
Publish_to：
JOURNAL OF FISH BIOLOGY
PMID：
36373002
GEMIN4, a potential therapeutic targets for patients with basal-like subtype breast cancer
点击查看 >>
Author：
Wu Liang, Zhang Yue, Zheng Chunlei, Zhao Fuqiang, Lin Yan
IF：
2.5000
Publish_to：
BMC Womens Health
PMID：
37507701
UTMD-mediated delivery of miR-21-5p inhibitor suppresses the development of lung cancer
点击查看 >>
Author：
Xiaoyu Zhou, Haitao Liu, Yingying Pang, Muqun Wang, Shengming Liu
IF：
2.4660
Publish_to：
TISSUE & CELL
PMID：
34979378
miR‑125b‑5p inhibits cell proliferation by targeting ASCT2 and regulating the PI3K/AKT/mTOR pathway in an LPS‑induced intestinal mucosa cell injury model
点击查看 >>
Author：
Huiming Guo, Jianyuan Gao, Yuan Qian, Huawei Wang, Jiang Liu, Qingyan Peng, Yong Zhou, Kunhua Wang
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
34149884
Post-transcriptional suppression of G protein-coupled receptor 15 (GPR15) by microRNA-1225 inhibits proliferation, migration, and invasion of human colorectal cancer cells
点击查看 >>
Author：
Guo Yuehui, Zhu Qingyun, Chen Shiwei, Li Yanxiang, Fu Daiquan, Qiao Delin, Ni Caifang
IF：
2.4060
Publish_to：
3 Biotech
PMID：
33708462
Overexpression of CRABP2 inhibits dexamethasone-induced apoptosis in human osteoblast cells
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Author：
Zhang Haiping, Yu Ziliang, Sun Farui, Jin Jin
IF：
2.3590
Publish_to：
Journal of Orthopaedic Surgery and Research
PMID：
33879199
Diclofenac sodium effectively inhibits the biofilm formation of Staphylococcus epidermidis
点击查看 >>
Author：
Xi Huimin, Luo Zhaoxia, Liu Mei-fang, Chen Qiang, Zhu Qing, yuan Lei, Sheng Yi-yun, Zhao Rui
IF：
2.3000
Publish_to：
ARCHIVES OF MICROBIOLOGY
PMID：
38847838
Allicin attenuates myocardial apoptosis, inflammation and mitochondrial injury during hypoxia-reoxygenation: an in vitro study
点击查看 >>
Author：
Deng Xinyi, Yang Peng, Gao Tong, Liu Mengru, Li Xianlun
IF：
2.2980
Publish_to：
BMC Cardiovascular Disorders
PMID：
33882833
Isolation and culture of rat intestinal mucosal microvascular endothelial cells using immunomagnetic beads
点击查看 >>
Author：
Yanmei Wu, Zhaoli Wang, Ge Hu, Tao Zhang
IF：
2.2870
Publish_to：
JOURNAL OF IMMUNOLOGICAL METHODS
PMID：
35675843
L-arginine reduces injury from heat stress to bovine intestinal epithelial cells by improving antioxidant and inflammatory response
点击查看 >>
Author：
Mengying Dou, Yao Zhang, Qi Shao, Jiali Zhu, Wang Li, Xueying Wang, Cai Zhang, Yuanxiao Li
IF：
2.2710
Publish_to：
ANIMAL BIOTECHNOLOGY
PMID：
34870558
miR-223-5p Suppresses OTX1 to Mediate Malignant Progression of Lung Squamous Cell Carcinoma Cells
点击查看 >>
Author：
Yunping Lu
IF：
2.2380
Publish_to：
Computational and Mathematical Methods in Medicine
PMID：
34306176
Circ_0000395 Promoted CRC Progression via Elevating MYH9 Expression by Sequestering miR-432-5p
点击查看 >>
Author：
Fan Leilei, Li Weiwei, Jiang Hongsheng
IF：
2.2200
Publish_to：
BIOCHEMICAL GENETICS
PMID：
35759156
GALNT2 targeted by miR-139-5p promotes proliferation of clear cell renal cell carcinoma via inhibition of LATS2 activation
点击查看 >>
Author：
Yi Haisheng, Liu Lingyun, Zhang Jingshun, Guo Kaimin, Cao Yin, Sun Penghao, Wang Hongliang
IF：
2.2000
Publish_to：
Discover Oncology
PMID：
38478152
Protective Effect of Topiroxostat on Myocardial Injury Induced by Lipopolysaccharide
点击查看 >>
Author：
Jiong Liu, Xiangdong Zhang, Yongguang Lao, Chunsheng Li, Yueming Chen, Deli Zhan, Weihua Ding
IF：
2.1920
Publish_to：
JOURNAL OF SURGICAL RESEARCH
PMID：
34815074
Clostridium butyricum Supernatant Regulates the Expression of RORγt in HCT-116 Cells by Inhibiting the TLR2/MyD88/NF-κB Signaling Pathway
点击查看 >>
Author：
Xie Ying, Zhou Linyan, Li Hui, Li Yan
IF：
2.1880
Publish_to：
CURRENT MICROBIOLOGY
PMID：
33675405
Circ_0004104 participates in the regulation of ox-LDL-induced endothelial cells injury via miR-942-5p/ROCK2 axis
点击查看 >>
Author：
Zhang Yuanyuan, Wang Shaojun, Guo Sicong, Zhang Xinzhong, Yang Chuan, Su Guangsheng, Wan Jiye
IF：
2.1740
Publish_to：
BMC Cardiovascular Disorders
PMID：
36460954
Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123
点击查看 >>
Author：
Yang Jun
IF：
2.1640
Publish_to：
Genes & Genomics
PMID：
35666458
Endothelial cell-specific molecule 1 (ESM1) promoted by transcription factor SPI1 acts as an oncogene to modulate the malignant phenotype of endometrial cancer
点击查看 >>
Author：
Yu He, Lu Lin, Yurong Ou, Xiaowen Hu, Chi Xu, Caizhi Wang
IF：
2.1230
Publish_to：
Open Medicine
PMID：
36117773
Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis
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Author：
Yangfa Chao, Wenting Huang, Zhiheng Xu, Ping Li, Shaodong Gu
IF：
2.1000
Publish_to：
Open Medicine
PMID：
37636994
Anticancer Activity of Methyl Protodioscin against Prostate Cancer by Modulation of Cholesterol-Associated MAPK Signaling Pathway via FOXO1 Induction
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Author：
Jie Chen, Puyan Qin, Zhanxia Tao, Weijian Ding, Yunlong Yao, Weifang Xu, Dengke Yin, Song Tan
IF：
2.0000
Publish_to：
BIOLOGICAL & PHARMACEUTICAL BULLETIN
PMID：
37005301
Calycosin Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice through the miR-375-3p/ROCK2 Axis
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Author：
Jie Yao, Mingfeng Cheng, Fan Yang
IF：
1.9000
Publish_to：
JOURNAL OF INVESTIGATIVE SURGERY
PMID：
37400250
LncRNA VPS9D1-AS1 Regulates MiR-187-3p/Fibroblast Growth Factor Receptor-Like 1 Axis to Promote Proliferation, Migration, and Invasion of Prostate Cancer Cells
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Author：
Wu Chenguang, Chen Jian, Wang Dong
IF：
1.8000
Publish_to：
CHINESE JOURNAL OF PHYSIOLOGY
PMID：
37929340
Red Sea Sponge Extract Callyspongia siphonella and its Metabolites Induced Anticancer Activity in 2D and 3D Culture of Colon Cancer Cells
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Author：
Faris A Alkhilaiwi
IF：
1.7900
Publish_to：
Asian Pacific Journal of Cancer Prevention
PMID：
39205585
Inhibition of lncRNA H19/miR-370-3p pathway mitigates neuronal apoptosis in an in vitro model of spinal cord injury (SCI)
点击查看 >>
Author：
Xin Li, Yan Qian, Kaihua Tang, Yang Li, Rui Tao, Chunyan Gong, Li Huang, Kaiwen Zou, Lindong Liu
IF：
1.7570
Publish_to：
Translational Neuroscience
PMID：
33708438
Two new flavonoid thioglucosides from the seeds of Lepidium apetalum
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Author：
Meng Li, Xiao-Lan Wang, Jing-Ke Zhang, Meng-Nan Zeng, Yan-Jun Sun, Hui Chen, Zhi-You Hao, Wei-Sheng Feng, Xiao-Ke Zheng
IF：
1.7000
Publish_to：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
PMID：
36946084
Investigation on the effect of ulinastatin on the apoptosis of vascular smooth muscle cells in rats with aortic dissection based on the Sirt1/FoxO3a pathway
点击查看 >>
Author：
Xiaopeng Peng, Haoyao Yuan, Guangtian Chen, Yuliang Guo, Qiuer Liang, Qiming Chen, Weidong Cao
IF：
1.6000
Publish_to：
CELLULAR AND MOLECULAR BIOLOGY
PMID：
38158682
Chromomycins from soil-derived Streptomyces sp. inhibit the growth of human non-small cell lung cancer cells by targeting c-FLIP
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Author：
Gao-Jie Li, Chen Wang, Wen-Die Wang, Yue Shang, Chao-Yang Zeng, Ai-Min Wang, Jing-Lin Bai, Jing Su, Ling Su, Shu-Yi Si, Li-Yan Yu, Mao-Luo Gan, Shu-Zhen Chen
IF：
1.3000
Publish_to：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
PMID：
38975979
WTAP-mediated m6A modification on BASP1 mRNA contributes to ferroptosis in AAA
点击查看 >>
Author：
Tian Zexiang, Li Wei, Wang Jian, Li Shuzhen
IF：
1.1000
Publish_to：
General Thoracic and Cardiovascular Surgery
PMID：
39969669
Schisandrin A Alleviates Inflammation and Oxidative Stress in Aβ25-35-Induced Alzheimer’s Disease in Vitro Model
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Author：
Siting Jia, Huibo Guan, Shujuan Zhang, Quan Li
IF：
1.0000
Publish_to：
ACTAS ESPANOLAS DE PSIQUIATRIA
PMID：
39403912
技术问答
（4）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
可以用于酵母等真菌吗?2023-12-21 19:32:32
您好，该试剂盒依据MTT可被线粒体内脱氢酶还原产生紫色结晶产物，而常用于哺乳动物细胞增殖剂毒性检测。理论上真菌线粒体也可参与反应，但这边目前未实际验证。
可以不弃含mtt的培养基，直接加formezan溶解液吗?2023-05-08 21:50:39
您好，不可以的，需要洗掉上清液，再加formezan溶解液。
请问一个试剂盒，可以做几组呀?2022-09-24 15:04:30
您好，试剂盒按照说明书中有不同规格每种组分对应的试剂量，实验中可以测定多少样本量还要考虑做平行复孔数量以及实验对照组设置等因素。
加入的新鲜培养基是 含有血清的还是不含有血清的?2022-08-23 11:16:19
您好，不含血清的培养基。