基因名 |
CCDC89 |
别名 |
CCDC89,BOIP |
英文名称 |
Recombinant human CCDC89 protein |
全名 |
coiled-coil domain containing 89 |
外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
运输条件 |
The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q8N998 |
Gene ID |
220388 |
分子量 |
41kDa |
区间范围 |
1-350aa |
背景说明 |
CCDC89 is a 374 amino acid cytoplasmic and nuclear protein that interacts with HRT1 and belongs to the CCDC89 family. The gene that encodes CCDC89 consists of more than 2,000 bases and maps to human chromosome 11q14.1. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
研究领域 |
炎症与自身免疫疾病 |
单位 |
支 |
属性分类 |
重组抗原 |
Y-研究领域 |
炎症与自身免疫疾病 |