Recombinant human KIR3DL2 protein_索莱宝|主营生物科研试剂&抗体|蛋白|多肽|试剂盒|专业定制化服务平台-Solarbio【网上商城】

SKU	北京总部	北京海淀	武汉	广州
P07290-10ug	咨询	咨询	咨询	咨询
P07290-50ug	咨询	咨询	咨询	咨询
P07290-100ug	咨询	咨询	咨询	咨询
P07290-1mg	咨询	咨询	咨询	咨询

基因名	KIR3DL2
别名	/
英文名称	Recombinant human KIR3DL2 protein
全名	Killer cell immunoglobulin-like receptor 3DL2
外观(性状)	Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度	≥85% by SDS-PAGE.
储存条件	Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度	1mg/ml by SDS-PAGE.
Swiss Prot	P43630
Gene ID	3812
分子量	33kDa
区间范围	41-338aa
背景说明	Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
应用	Immunology research
来源	E.coli
纯化方法	NI-NTA affinity purification
溶剂	Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素	Not measured
生物活性	NO
标签信息	With a 6×His tag at the N/C-terminus.
规格	10ug 50ug 100ug 1mg
单位	支
属性分类	重组抗原