Recombinant human EXOSC5 protein_索莱宝|主营生物科研试剂&抗体|蛋白|多肽|试剂盒|专业定制化服务平台-Solarbio【网上商城】

SKU	北京总部	北京海淀	武汉	广州
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基因名	EXOSC5
别名	EXOSC5，CML28，RRP46
英文名称	Recombinant human EXOSC5 protein
全名	exosome component 5
外观(性状)	Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度	≥85% by SDS-PAGE.
储存条件	Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度	1mg/ml by SDS-PAGE.
Swiss Prot	Q9NQT4
Gene ID	56915
分子量	25.2kDa
区间范围	1-235aa
背景说明	Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR and/or Ig variable region somatic hypermutation (SHM by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9 is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
应用	Immunology research
来源	E.coli
纯化方法	NI-NTA affinity purification
溶剂	Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素	Not measured
生物活性	NO
标签信息	With a 6×His tag at the N/C-terminus.
规格	10ug 50ug 100ug 1mg
单位	支
属性分类	重组抗原