基因名 |
EWSR1 |
别名 |
RNA-binding protein EWS |
英文名称 |
Recombinant human EWSR1 protein |
全名 |
Ewing sarcoma breakpoint region 1 |
外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
运输条件 |
The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q01844-3 |
Gene ID |
2130 |
交叉反应 |
Human Mouse Rat (Bovine Zebrafish) |
分子量 |
31kDa |
区间范围 |
51-350aa |
背景说明 |
This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009] |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
单位 |
支 |
属性分类 |
重组抗原 |