中文
英语
牛胰岛素
CAS:No.11070-73-8
英文名称:Insulin from bovine pancreas
分子式:No data available
储存条件:Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year
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产品简介
| CAS | No.11070-73-8 |
| 中文名称 | 牛胰岛素 |
| 英文名称 | Insulin from bovine pancreas |
| 分子式 | No data available |
| 溶解性 | Soluble in Water ≥10 mg/mL(Need ultrasonic and add HCl to help dissolve) |
| 酶活/效价 | ≥27U/mg |
| 来源 | 牛胰腺 |
| 外观(性状) | White to off-white Solid |
| 储存条件 | Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 234-291-2 |
| MDL | MFCD00131380 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC( =O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C @H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H ](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H] (CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[ C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@ @H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CSSC[C@@H ](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)C(C)C )CO)C)NC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C @H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O )[C@H](CC4=CC=CC=C4)N)CO)CC5=CN=CN5)CC(C)C)C(C)C)CCC(=O)O)C)CC(C) C)CC6=CC=C(C=C6)O)CC(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O )C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC7=CC=CC=C7)C(= O)N[C@@H](CC8=CC=CC=C8)C(=O)N[C@@H](CC9=CC=C(C=C9)O)C(=O)N[ C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[ C@@H](C)C(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O)CC1=CC=C(C=C1)O)CC(=O) N)CCC(=O)O)CC(C)C)CCC(=O)N)CC1=CC=C(C=C1)O)CC(C)C)CO)NC(=O)CN |
| InChIKey | CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC( =O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C @H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H ](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H] (CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[ C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@ @H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CSSC[C@@H ](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)C(C)C )CO)C)NC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C @H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O )[C@H](CC4=CC=CC=C4)N)CO)CC5=CN=CN5)CC(C)C)C(C)C)CCC(=O)O)C)CC(C) C)CC6=CC=C(C=C6)O)CC(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O )C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC7=CC=CC=C7)C(= O)N[C@@H](CC8=CC=CC=C8)C(=O)N[C@@H](CC9=CC=C(C=C9)O)C(=O)N[ C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[ C@@H](C)C(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)O)CC1=CC=C(C=C1)O)CC(=O) N)CCC(=O)O)CC(C)C)CCC(=O)N)CC1=CC=C(C=C1)O)CC(C)C)CO)NC(=O)CN |
| InChI | InChI=1S/C254H377N65O75S6/c1-29-131(24)205(312-192(334)103-256)250(389)317-204(130(22)23)246(385)287-158(74- 81-199(344)345)216(355)281-155(70-77-188(260)330)220(359)307-183-116-399-400-117-184-242(381)305- 177(110-321)238(377)293-161(87-122(6)7)223(362)294-167(94-139-52-60-145(324)61-53-139)226( 365)282-153(68-75-186(258)328)217(356)289-160(86-121(4)5)221(360)284-157(73-80-198(342)343) 219(358)301-173(100-189(261)331)233(372)297-169(96-141-56-64-147(326)65-57-141)229(368)308-182( 241(380)303-175(253(393)394)102-191(263)333)115-398-396-113-180(212(351)270-106-193(335)277-152(71- 78-196(338)339)215(354)280-150(50-41-83-268-254(264)265)210(349)269-107-194(336)278-165(92-137- 45-35-31-36-46-137)225(364)296-166(93-138-47-37-32-38-48-138)228(367)298-170(97-142-58- 66-148(327)67-59-142)236(375)318-206(135(28)323)251(390)319-84-42-51-185(319)244(383)285-151( 49-39-40-82-255)213(352)276-134(27)252(391)392)310-248(387)202(128(18)19)315-234(373)163(89-124(10) )11)291-227(366)168(95-140-54-62-146(325)63-55-140)295-222(361)159(85-120(2)3)288-207(346 )132(25)274-214(353)156(72-79-197(340)341)286-245(384)201(127(16)17)314-235(374)164(90-125(12) )13)292-231(370)172(99-144-105-267-119-273-144)300-237(376)176(109-320)279-195(337)108-271-211(350) )179(112-395-397-114-181(309-243(183)382)240(379)275-133(26)208(347)304-178(111-322)239(378)316-203 (129(20)21)249(388)311-184)306-224(363)162(88-123(8)9)290-230(369)171(98-143-104-266-118-272 -143)299-218(357)154(69-76-187(259)329)283-232(371)174(101-190(262)332)302-247(386)200(126(14)15 )313-209(348)149(257)91-136-43-33-30-34-44-136/h30-38，43-48，52-67，104-105，118-135，149-185，200-206，320-327H，29 ，39-42，49-51，68-103，106-117，255-257H2，1-28H3，(H2，258，328)(H2，259，329)(H2，260，330)(H2，261，331)(H2，262，332)(H2，263，333)(H，266，272)(H，267，273)(H，269，349)(H，270，351)(H，271，350)(H，274，353)(H，275，379)(H， 276，352)(H，277，335)(H，278，336)(H，279，337)(H，280，354)(H，281，355)(H，282，365)(H，283，371)(H，284，360)(H，285，383)(H， 286，384)(H，287，385)(H，288，346)(H，289，356)(H，290，369)(H，291，366)(H，292，370)(H，293，377)(H，294，362)(H，295，361)(H， 296，364)(H，297，372)(H，298，367)(H，299，357)(H，300，376)(H，301，358)(H，302，386)(H，303，380)(H，304，347)(H，305，381)(H， 306，363)(H，307，359)(H，308，368)(H，309，382)(H，310，387)(H，311，388)(H，312，334)(H，313，348)(H，314，374)(H，315，373)(H， 316，378)(H，317，389)(H，318，375)(H，338，339)(H，340，341)(H，342，343)(H，344，345)(H，391，392)(H，393，394)(H4，264，265，268)/t131- ，132-，133-，134-，135+，149-，150-，151-，152-，153-，154-，155-，156-，157-，158-，159-，160-，161 -，162-，163-，164-，165-，166-，167-，168-，169-，170-，171-，172-，173-，174-，175-，176-，177-， 178-，179-，180-，181-，182-，183-，184-，185-，200-，201-，202-，203-，204-，205-，206-/m0/s1 |
| PubChem CID | 16131099 |
| 靶点 | Insulin Receptor |
| 通路 | Endocrinology & Hormones |
| 背景说明 | 胰岛素是一种蛋白质类激素,体内胰岛素是由胰岛β细胞分泌的,具有降低血糖的活性。本产品来源于牛胰腺。 |
| 规格 | 5mg 10mg 25mg 50mg 100mg |
| 单位 | 瓶 |
使用本产品的案例（仅供参考）
In Vitro
Cell （成脂分化；1.9 μM Insulin,2d；10 μg/mL Insulin,14d/change the medium every two days）
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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PMID：
38685543
Aptamer-Functionalized AuNCs Nanogel for Targeted Delivery of Docosahexaenoic Acid to Induce Browning of White Adipocytes
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Author：
Hejie Xu, Jialuo Ding, Yanhui Du, Le Li, Yeying Li, Mengyuan Zhao, Yu Su, Zhenkun Lin
IF：
7.5710
Publish_to：
Journal of Materials Chemistry B
PMID：
37203464
PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis
点击查看 >>
Author：
Jia Linglu, Li Dongfang, Wang Ya-Nan, Zhang Dongjiao, Xu Xin
IF：
7.4000
Publish_to：
Journal of Translational Medicine
PMID：
36732787
Prognostic value of gamma-interferon-inducible lysosomal thiol reductase expression in female patients diagnosed with breast cancer
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Author：
Chunmiao Ye, Wenzhong Zhou, Fei Wang, Gengshen Yin, Xiaoxia Zhang, Lingyu Kong, Zhongcheng Gao, Man Feng, Chengjun Zhou, Dianshui Sun, Lei Wang, Liyuan Liu, Chao Zheng, Yujuan Xiang, Mingming Guo, Shuya Huang, Zhigang Yu
IF：
7.3960
Publish_to：
INTERNATIONAL JOURNAL OF CANCER
PMID：
34648659
Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways
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Author：
Wenwen Yang, Linwensi Zhu, Shanglei Lai, Qinchao Ding, Tiantian Xu, Rui Guo, Xiaobing Dou, Hui Chai, Zhiling Yu, Songtao Li
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
35355867
Epithelium-Penetrable Nanoplatform with Enhanced Antibiotic Internalization for Management of Bacterial Keratitis
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Author：
Yanlong Zhang, Yunjian Yu, Gang Li, Xinge Zhang, Zhongming Wu, Ling Lin
IF：
6.9880
Publish_to：
BIOMACROMOLECULES
PMID：
33880923
AN698/40746067 suppresses bone marrow adiposity to ameliorate hyperlipidemia-induced osteoporosis through targeted inhibition of ENTR1
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Author：
Huiping Ren, Kai Mao, Xin Yuan, Yuqing Mu, Shuaiqi Zhao, Xin Fan, Lina Zhu, Zhou Ye, Jing Lan
IF：
6.9000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38810405
Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone
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Author：
Li Tao, Xu Yingxing, Wang Yingzhen, Jiang Yaping
IF：
6.8320
Publish_to：
Stem Cell Research & Therapy
PMID：
33407832
Casein Lactose-Glycation of the Maillard-Type Attenuates the Anti-Inflammatory Potential of Casein Hydrolysate to IEC-6 Cells with Lipopolysaccharide Stimulation
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Author：
Na Chen, Yu Fu, Zhen-Xing Wang, Xin-Huai Zhao
IF：
6.7060
Publish_to：
Nutrients
PMID：
36501097
TRIM16 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Modulating CHIP-Mediated Degradation of RUNX2
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Author：
Zhao Yi, Zhai Qiaoli, Liu Hong, Xi Xun, Chen Shuai, Liu Dongxu
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
33490087
Combining single-cell profiling and functional analysis explores the role of pseudogenes in human early embryonic development
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Author：
Mengyao Sun, Le Chang, Liu He, Li Wang, Zhengyang Jiang, Yanmin Si, Jia Yu, Yanni Ma
IF：
6.6000
Publish_to：
Journal of Genetics and Genomics
PMID：
39032861
Diallyl Trisulfide Prevents Adipogenesis and Lipogenesis by Regulating the Transcriptional Activation Function of KLF15 on PPARγ to Ameliorate Obesity
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Author：
Yanzhou Hu, Jia Xu, Ruxin Gao, Ye Xu, Bingxin Huangfu, Charles Asakiya, Xianghui Huang, Feng Zhang, Kunlun Huang, Xiaoyun He, Yunbo Luo
IF：
6.5750
Publish_to：
MOLECULAR NUTRITION & FOOD RESEARCH
PMID：
35983694
Bovine α-lactalbumin-derived peptides attenuate TNF-α-induced insulin resistance and inflammation in 3T3-L1 adipocytes through inhibiting JNK and NF-κB signaling
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Author：
Jing Gao, Kairui Guo, Min Du, Xueying Mao
IF：
6.3170
Publish_to：
Food & Function
PMID：
35142310
The anti-inflammatory effects of apigenin and genistein on the rat intestinal epithelial (IEC-6) cells with TNF-α stimulation in response to heat treatment
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Author：
Shi-Qing Cai, Zhi-Mei Tang, Cen Xiong, Fei-Fei Wu, Jun-Ren Zhao, Qiang Zhang, Li Wang, Xiao-Nan Zhang, Xin-Huai Zhao
IF：
6.2690
Publish_to：
Current Research in Food Science
PMID：
36686365
The Role of Insulin-like Peptide in Maintaining Hemolymph Glucose Homeostasis in the Pacific White Shrimp Litopenaeus vannamei
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Author：
Manwen Su, Xiaojun Zhang, Jianbo Yuan, Xiaoxi Zhang, Fuhua Li
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
35328689
Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells via the IGF1R/AKT1/RHOA signaling pathway
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Author：
Jie Yang, Sen Qin, Nannan Sun, Yang Cai, Junling Li, Zhuhui Zhai, Jie An, Hejie Wang, Rong Du, Jian Qin
IF：
6.2000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
39083871
Whole Grain Proso Millet (Panicum miliaceum L.) Attenuates Hyperglycemia in Type 2 Diabetic Mice: Involvement of miRNA Profile
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Author：
Xu Deng, Jiayi Liang, Lehui Wang, Li Niu, Jin Xiao, Qianqian Guo, Xuebo Liu, Chunxia Xiao
IF：
6.1000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
37294881
Stimulation of hair growth by Tianma Gouteng decoction: Identifying mechanisms based on chemical analysis, systems biology approach, and experimental evaluation.
点击查看 >>
Author：
Yanyan Zhang, Shiqian Zhang, Yunluan Long, Wuji Wang, Fanpan Du, Jingjie Li, Feng Jin, Zheng Li
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
36588691
KRAS Affects Adipogenic Differentiation by Regulating Autophagy and MAPK Activation in 3T3-L1 and C2C12 Cells
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Author：
Wenjie Yu, Cheng-Zhen Chen, Yanxia Peng, Ze Li, Yan Gao, Shuang Liang, Bao Yuan, Nam-Hyung Kim, Hao Jiang, Jia-Bao Zhang
IF：
5.9240
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
34948427
Enhancement of BCAT2-Mediated Valine Catabolism Stimulates β-Casein Synthesis via the AMPK-mTOR Signaling Axis in Bovine Mammary Epithelial Cells
点击查看 >>
Author：
Xinling Wang, Jie Xu, Hanfang Zeng, Zhaoyu Han
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
35916279
PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis
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Author：
Wang Yang, Wang Jieyi, Chen Lan, Chen Zhuo, Wang Tong, Xiong Shuting, Zhou Tong, Wu Guang, He Licai, Cao Jiawei, Liu Min, Li Hongzhi, Gu Haihua
IF：
5.8000
Publish_to：
Cancer Cell International
PMID：
38102641
Arginine alleviates Clostridium perfringens α toxin-induced intestinal injury in vivo and in vitro via the SLC38A9/mTORC1 pathway
点击查看 >>
Author：
Wang Xiaohui, Zhang Tong, Li Wenli, Wang Heliang, Yan Lei, Zhang Xiaowen, Zhao Lianwen, Wang Nianxue, Zhang Beibei
IF：
5.7000
Publish_to：
Frontiers in Immunology
PMID：
38638435
Transcriptomic Analysis Reveals Fibroblast Growth Factor 11 (FGF11) Role in Brown Adipocytes in Thermogenic Regulation of Goats
点击查看 >>
Author：
Tingting Jiang, Duo Su, Xin Liu, Yan Wang, Linjie Wang
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
37446019
Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells
点击查看 >>
Author：
Bai Yu, Du Qiang, Zhang Le, Li Ling, Wang Nana, Wu Bo, Li Ping, Li Ling
IF：
5.5550
Publish_to：
Frontiers in Endocrinology
PMID：
34163433
In vitro transdifferentiated signatures of goat preadipocytes into mammary epithelial cells revealed by DNA methylation and transcriptome profiling
点击查看 >>
Author：
Xiao-Ru Yan, Tao Shi, Jia-Ying Xiao, Ya-Fang Liu, Hui-Ling Zheng
IF：
5.4860
Publish_to：
JOURNAL OF BIOLOGICAL CHEMISTRY
PMID：
36257406
Exploring the protective effect of Gynura procumbens against type 2 diabetes mellitus by network pharmacology and validation in C57BL/KsJ db/db mice
点击查看 >>
Author：
Sa Guo, Hui Ouyang, Wendi Du, Junmao Li, Mi Liu, Shilin Yang, Mingzhen He, Yulin Feng
IF：
5.3960
Publish_to：
Food & Function
PMID：
33502413
Gadolinium-Bisphosphonate Nanoparticle-Based Low-Dose Radioimmunotherapy for Osteosarcoma
点击查看 >>
Author：
Shaodian Zhang, Yanxian Wu, Jiangkun Yu, Chunjie Ma, Yangyun Wang, Yong Wang, Liubing Li, Leshuai W. Zhang
IF：
5.3950
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
36383732
A novel electrochemical insulin aptasensor: From glassy carbon electrodes to disposable, single-use laser-scribed graphene electrodes
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Author：
Jinjin Liu, Bicheng Zhu, Hui Dong, Yintang Zhang, Maotian Xu, Jadranka Travas-Sejdic, Zhu Chang
IF：
5.3730
Publish_to：
BIOELECTROCHEMISTRY
PMID：
34794112
Alantolactone ameliorates cancer cachexia-associated muscle atrophy mainly by inhibiting the STAT3 signaling pathway
点击查看 >>
Author：
Qiang Shen, Ji-Xia Kuang, Chun-Xiao Miao, Wan-Li Zhang, Yi-Wei Li, Xiong-Wen Zhang, Xuan Liu
IF：
5.3400
Publish_to：
PHYTOMEDICINE
PMID：
34861585
Analyses of key mRNAs and lncRNAs for different osteo-differentiation potentials of periodontal ligament stem cell and gingival mesenchymal stem cell
点击查看 >>
Author：
Linglu Jia, Yunpeng Zhang, Dongfang Li, Wenjing Zhang, Dongjiao Zhang, Xin Xu
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
34028189
Hepatotoxicity of copper sulfide nanoparticles towards hepatocyte spheroids using a novel multi-concave agarose chip method
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Author：
Tianyan Jiang, Haoxiang Guo, Ya-Nan Xia, Yun Liu, Dandan Chen, Guibin Pang, Yahui Feng, Huan Yu, Yanxian Wu, Shaodian Zhang, Yangyun Wang, Yong Wang, Hairuo Wen, Leshuai W Zhang
IF：
5.3070
Publish_to：
Nanomedicine
PMID：
34184559
TRAF6-mediated ubiquitination of AKT1 in the nucleus occurs in a β-arrestin2-dependent manner upon insulin stimulation
点击查看 >>
Author：
Li Hu, Haiping Liu, Haixiang Ma, Xingyue Zeng, Yongkai Cao, Bing Liu, Huijun Li, Xiaohan Zhang
IF：
5.3000
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
38871335
Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition
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Author：
Jian Chen, Xiaoqin Ding, Ruoyun Wu, Bei Tong, Lei Zhao, Han Lv, Xiuhua Meng, Yan Liu, Bingru Ren, Jing Li, Tunyu Jian, Weilin Li
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
34783554
Tyrosinase Inhibitory Peptides from Enzyme Hydrolyzed Royal Jelly: Production,Separation,Identification and Docking Analysis
点击查看 >>
Author：
Zhen Ge, Jun-Cai Liu, Jian-An Sun, Xiang-Zhao Mao
IF：
5.2000
Publish_to：
Foods
PMID：
37297482
Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment.
点击查看 >>
Author：
Denghao Huang, Jie Lei, Xingrui Li, Zhonghao Jiang, Maoxuan Luo, Yao Xiao
IF：
5.1310
Publish_to：
Stem Cells International
PMID：
36199627
Combination treatment strategies with a focus on rosiglitazone and adriamycin for insulin resistant liver cancer
点击查看 >>
Author：
Yi-Fan Dang, Shao-Hui Yang, Xiao-Ning Jiang, Fu-Lian Gong, Xiao-Xia Yang, Yan-Na Cheng, Xiu-Li Guo
IF：
5.1210
Publish_to：
JOURNAL OF DRUG TARGETING
PMID：
33115283
The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity
点击查看 >>
Author：
Yi Chu, Sisi Gui, Yazhen Zheng, Jingwu Zhao, Yaxiang Zhao, Yingying Li, Xiaodong Chen
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38402928
Collagen Membrane Derived from Fish Scales for Application in Bone Tissue Engineering
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Author：
Liang Chen, Guoping Cheng, Shu Meng, Yi Ding
IF：
4.9670
Publish_to：
Polymers
PMID：
35808577
A novel study on the immunomodulatory effect of umbilical cord derived mesenchymal stem cells pretreated with traditional Chinese medicine Asarinin
点击查看 >>
Author：
Haiping He, Tonghua Yang, Fan Li, Lihua Zhang, Xiaosui Ling
IF：
4.9320
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
34492537
Immune Rejection Mediated by prf1 and gzmb Affects the Colonization of Fat Greenling (Hexagrammos otakii) Spermatogonia in Heterotransplantation
点击查看 >>
Author：
Xi Zhao, Ying Chen, Rui Li, Yu Men, Kai Yan, Zibin Li, Wenxiu Cai, Yan He, Jie Qi
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
38791196
1-Methylnicotinamide promotes hepatic steatosis in mice: A potential mechanism in chronic alcohol-induced fatty liver disease
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Author：
Shanglei Lai, Yue Ma, Liuyi Hao, Qinchao Ding, Kaixin Chang, Hui Zhuge, Jiannan Qiu, Tiantian Xu, Xiaobing Dou, Songtao Li
IF：
4.8000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
PMID：
36690322
The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis
点击查看 >>
Author：
Ranran Zhang, Xudong Peng, Jing Lin, Yingxue Zhang, Lu Zhan, Xue Tian, Jiao Yin, Guiqiu Zhao
IF：
4.7990
Publish_to：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
PMID：
34236384
Senolytic elimination of senescent cells improved periodontal ligament stem cell-based bone regeneration partially through inhibiting YAP
点击查看 >>
Author：
Linglu Jia, Han Xiao, Zhenghao Hao, Shaoqing Sun, Wenxi Zhao, Zikai Gong, Weiting Gu, Yong Wen
IF：
4.6000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
PMID：
39971252
Identification of miRNA in Sheep Intramuscular Fat and the Role of miR-193a-5p in Proliferation and Differentiation of 3T3-L1
点击查看 >>
Author：
Han Fuhui, Zhou Lisheng, Zhao Le, Wang Lei, Liu Lirong, Li Haijuan, Qiu Jixian, He Jianning, Liu Nan
IF：
4.5990
Publish_to：
Frontiers in Genetics
PMID：
33936163
RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goats
点击查看 >>
Author：
Liu Xin, Zhu Yuehua, Zhan Siyuan, Zhong Tao, Guo Jiazhong, Cao Jiaxue, Li Li, Zhang Hongping, Wang Linjie
IF：
4.5470
Publish_to：
BMC GENOMICS
PMID：
35255830
Pyrazolone compounds could inhibit CES1 and ameliorates fat accumulation during adipocyte differentiation
点击查看 >>
Author：
Dan-Dan Wang, Zhen-Zhen Wang, Wen-Cai Liu, Xing-Kai Qian, Ya-Di Zhu, Tie-Gang Wang, Shu-Mei Pan, Li-Wei Zou
IF：
4.5000
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
38878751
The In Vitro Anti-Inflammatory Activities of Galangin and Quercetin towards the LPS-Injured Rat Intestinal Epithelial (IEC-6) Cells as Affected by Heat Treatment
点击查看 >>
Author：
Shi-Qing Cai, Qiang Zhang, Xin-Huai Zhao, Jia Shi
IF：
4.4120
Publish_to：
MOLECULES
PMID：
34946578
Electroporation-based Easi-CRISPR yields biallelic insertions of EGFP-HiBiT cassette in immortalized chicken oviduct epithelial cells
点击查看 >>
Author：
Lingkang Liu, Jinyu Wei, Chen Chen, Qianxue Liang, Boyong Wang, Wende Wu, Gonghe Li, Xibang Zheng
IF：
4.4000
Publish_to：
POULTRY SCIENCE
PMID：
37806084
Reactions of Cisplatin with Thioredoxin-1 Regulate Intracellular Redox Homeostasis
点击查看 >>
Author：
Shenghu Wang, Siming Yuan, Hongze Hu, Jiahai Zhang, Kaiming Cao, Yu Wang, Yangzhong Liu
IF：
4.3000
Publish_to：
INORGANIC CHEMISTRY
PMID：
38850241
PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells
点击查看 >>
Author：
Wei Tang, Yu Wu, Xin Qi, Rilei Yu, Zhimin Lu, Ao Chen, Xinglong Fan, Jing Li
IF：
4.2480
Publish_to：
Cancer Biology & Medicine
PMID：
34403222
Ferroptosis inhibitors reduce celastrol toxicity and preserve its insulin sensitizing effects in insulin resistant HepG2 cells
点击查看 >>
Author：
Jia-jia Liu, Xue Zhang, Bang-lan Cai, Man-man Qi, Yong-bin Chi, Bin Peng, Deng-hai Zhang
IF：
4.2000
Publish_to：
Journal of Integrative Medicine-JIM
PMID：
38565435
Andrographolide induced ferroptosis in multiple myeloma cells by regulating the P38/Nrf2/HO-1 pathway
点击查看 >>
Author：
Wenxia Li, Hangjie Fu, Liuyuan Fang, Hui Chai, Bin Ding, Shenxian Qian
IF：
4.1140
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
37172672
Methionine Promotes Milk Protein Synthesis via the PI3K-mTOR Signaling Pathway in Human Mammary Epithelial Cells
点击查看 >>
Author：
Peizhi Li, Xibi Fang, Guijie Hao, Xiaohui Li, Yue Cai, Yuhao Yan, Liting Zan, Runjun Yang, Boqun Liu
IF：
4.1000
Publish_to：
Metabolites
PMID：
37999245
Supplementation of mixed Lactobacillus alleviates metabolic impairment, inflammation, and dysbiosis of the gut microbiota in an obese mouse model
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Author：
Shulin Hou, Ruining Li, Yunyun Zhang, Ping Liang, Haishan Yang, Huili He, Lei Wang, Yaojun Sun, Tianru Jin, Zhizhen Liu, Jun Xie
IF：
4.0000
Publish_to：
Frontiers in Nutrition
PMID：
40206949
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch
点击查看 >>
Author：
Xun Xi, Yi Zhao, Hong Liu, Zixuan Li, Shuai Chen, Dongxu Liu
IF：
3.9050
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
33865812
Adipose tissue reconstruction facilitated with low immunogenicity decellularized adipose tissue scaffolds
点击查看 >>
Author：
Xun Yang, Lijuan Jin, Miaomiao Xu, Xiao Liu, Zhikai Tan, Lijun Liu
IF：
3.9000
Publish_to：
Biomedical Materials
PMID：
38518362
MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus
点击查看 >>
Author：
Huiting Zhang, Yi Jiang, Shenglan Zhu, Lijie Wei, Xuan Zhou, Peng Gao, Jingyi Zhang, Yuting Chen, Yuanyuan Du, Chenyun Fang, Rui Su, Jiaqi Li, Shaoshuai Wang, Ling Feng
IF：
3.8000
Publish_to：
PLACENTA
PMID：
38325118
Selenium Deficiency Induces Autophagy in Chicken Bursa of Fabricius Through ChTLR4/MyD88/NF-κB Pathway
点击查看 >>
Author：
Zhang Ruili, Liu Qing, Guo Rong, Zhang Di, Chen Yang, Li Guangxing, Huang Xiaodan
IF：
3.7380
Publish_to：
BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
34467441
Improved oral delivery of insulin by PLGA nanoparticles coated with 5β-cholanic acid conjugated glycol chitosan
点击查看 >>
Author：
Weizhi Wang, Chenggong Yu, Fangfang Zhang, Yuxuan Li, Bo Zhang, Jie Huang, Zhijun Zhang, Liang Jin
IF：
3.7150
Publish_to：
Biomedical Materials
PMID：
34571498
Establishment of myoblast cell line and identification of key genes regulating myoblast differentiation in a marine teleost, Sebastes schlegelii
点击查看 >>
Author：
Xiangfu Kong, Xuangang Wang, Moli Li, Weihao Song, Kejia Huang, Fengyan Zhang, Quanqi Zhang, Jie Qi, Yan He
IF：
3.6880
Publish_to：
GENE
PMID：
34352298
Insufficient sleep disrupts glucose metabolism during pregnancy by inhibiting PGC-1α.
点击查看 >>
Author：
Hao Wu, Cong Lu, Xing Li, Xianming Xu, Sufang Wu
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
36544637
Lpcat3 deficiency promotes palmitic acid-induced 3T3-L1 mature adipocyte inflammation through enhanced ROS generation: Lpcat3 deficiency promotes adipocyte inflammation
点击查看 >>
Author：
Jiachun Hu, Yan Deng, Tingbo Ding, Jibin Dong, Yuning Liang, Bin Lou
IF：
3.5110
Publish_to：
ACTA BIOCHIMICA ET BIOPHYSICA SINICA
PMID：
36331295
Aptamer-modified atomically precise gold nanoclusters as targeted nanozymes to scavenge reactive oxygen species in white adipocytes
点击查看 >>
Author：
Jialuo Ding, Yanhui Du, Xinying Hu, Mengyuan Zhao, Yeying Li, Le Li, Yu Su, Zhenkun Lin
IF：
3.5000
Publish_to：
NANOTECHNOLOGY
PMID：
37263189
Feline umbilical cord-derived mesenchymal stem cells: isolation,identification,and antioxidative stress role through NF-κB signaling pathway
点击查看 >>
Author：
Zhu-Hui Zhai, Jun Li, Zhao You, Yang Cai, Jie Yang, Jie An, Di-Peng Zhao, He-Jie Wang, Min-Min Dou, Rong Du, Jian Qin
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
37303730
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells
点击查看 >>
Author：
Zhihui Jing, Xinran Feng, Xin Li, Xiaoyu Zhang, Chunling Pan
IF：
3.4000
Publish_to：
JOURNAL OF PERIODONTAL RESEARCH
PMID：
38699861
Transcriptome analysis of long non-coding RNAs reveals NR_015556 lncRNA is a novel regulator for adipocyte differentiation
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Author：
Changqing Zuo, Yaqiong Pan, Dan Leng, Xiuju Chen, Fanghongniu Dong, Zhanying Lin, Zhong Dai, Zonggui Wang
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
35231655
Modified CD40L-Activated B-Cell Proliferation Model for Validating the Suppressive Activity of CD40-CD154 Pathway Inhibitors
点击查看 >>
Author：
Man Zhang, Hao Feng, Yahui Huang, Tianyi Hu, Jiaxiang Du, Yong Wang, Song Chen, Dengke Pan, Lan Zhu, Gang Chen
IF：
3.3000
Publish_to：
XENOTRANSPLANTATION
PMID：
39994946
Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice
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Author：
Chunyan Zhao, Xiaoteng Cui, Yan Zhao, Baoxin Qian, Nan Zhang, Lingbiao Xin, Chuanbo Ha, Jie Yang, Xinting Wang, Xingjie Gao
IF：
3.2690
Publish_to：
Bioengineered
PMID：
34608846
Maternal Dietary Supplementation with γ-Aminobutyric Acid Alleviated Oxidative Stress in Gestating Sows and Their Offspring by Regulating GABRP
点击查看 >>
Author：
Xiaoyi Liu, Lili Jiang, Jiaman Pang, Yujun Wu, Yu Pi, Jianjun Zang, Junjun Wang, Dandan Han
IF：
3.2310
Publish_to：
Animals
PMID：
36230278
Establishment of an immortalized sheep mammary epithelial cell line for studying milk fat and protein synthesis
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Author：
Shujuan Liu, Zhanhang Wang, Heran Cao, Jiashun Tong, Jiuzeng Cui, Long Li, Qiqi Bu, Yan Li, Tianqi Jin, Xiaopeng An, Lei Zhang, Yuxuan Song
IF：
3.2000
Publish_to：
JOURNAL OF FOOD SCIENCE
PMID：
39322983
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice
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Author：
Xianghe Chen, Kang Yang, Xing Jin, Zhaoxiang Meng, Bo Liu, Huilin Yu, Pengcheng Lu, Kui Wang, Zhangling Fan, Ziang Tang, Feng Zhang, Chengye Liu
IF：
3.1680
Publish_to：
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
PMID：
34168475
Effect of Insulin Receptor on Juvenile Hormone Signal and Fecundity in Spodoptera litura (F.)
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Author：
Xue Pan, Yanfang Pei, Cuici Zhang, Yaling Huang, Ling Chen, Liqiong Wei, Chuanren Li, Xiaolin Dong, Xiang Chen
IF：
3.1390
Publish_to：
Insects
PMID：
36005325
Nrf-2/ROS/NF-κB pathway is modulated by cynarin in human mesenchymal stem cells in vitro from ankylosing spondylitis
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Author：
Chenyu Song, Kaiyang Wang, Bangping Qian, Jingshun Lu, Mu Qiao, Yong Qiu, Bin Wang, Yang Yu
IF：
3.1000
Publish_to：
CTS-Clinical and Translational Science
PMID：
38450992
Identification of TFR2 as a novel ferroptosis related gene that serves an important role in prognosis and progression of triple negative breast cancer
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Author：
Yan Yang, Jie Du, Yun-Fei Huang, Wei He, Li Liu, Dan Li, Rui Chen
IF：
2.9000
Publish_to：
Oncology Letters
PMID：
38106522
Microbial creation of β-Nicotinamide mononucleotide and its regulation of lipid metabolism in the liver of high-fat diet mice
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Author：
Xutong Tian, Youyan Rong, Juyue Luo, Yaping Zhao, Tiantian Zhou, Yu Zeng, Kai Hong, Liang Jiang, Jianying Yang, Yumeng Li, Xin Wu
IF：
2.8000
Publish_to：
CELL BIOCHEMISTRY AND FUNCTION
PMID：
38953407
Mechanisms of Mitochondria-Mediated Apoptosis During Eimeria tenella Infection
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Author：
Rui Bai, Hui Wang, Tiantian Yang, Yuqi Yan, Shuying Zhu, Chenyang Lv, Yang Pei, Jiale Guo, Jianhui Li, Xiaozhen Cui, Xiaoling Lv, Mingxue Zheng
IF：
2.7000
Publish_to：
Animals
PMID：
40003058
Apigenin Suppresses the Warburg Effect and Stem-like Properties in SOSP-9607 Cells by Inactivating the PI3K/Akt/mTOR Signaling Pathway
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Author：
Yihua Shi, Kai Lian, Jiguang Jia
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
35310040
Differential expression of microRNAs in serum exosomes of obese and non-obese mice and analysis of their function
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Author：
Changzan Wang, Xianghui Li, Wenying Yi, Jiawei Kang, Nuerbiye Nuermaimaiti, Yaqun Guan
IF：
2.6000
Publish_to：
GENE
PMID：
38838872
PI3KR1 and AKT1 in largemouth bass (Micropterus salmoides): molecular cloning, characterization, and its involvement in the alleviation of hepatic glycogen deposition caused by insulin inclusion in vitro
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Author：
Li Yuru, Chen Shiwen, Liu Yijun, Liu Pingping, Li Songlin, Liu Ning
IF：
2.5000
Publish_to：
FISH PHYSIOLOGY AND BIOCHEMISTRY
PMID：
39150597
miR‑638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells
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Author：
Li Ma, Wei Zhang, Yaofeng Jin, Xiaomei Bai, Qiaoling Yu
IF：
2.4470
Publish_to：
Experimental and Therapeutic Medicine
PMID：
34630673
Circ_0039569 contributes to the paclitaxel resistance of endometrial cancer via targeting miR-1271-5p/PHF6 pathway
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Author：
Li Jia, Zhang Zhidong, Hu Yuanjing, Wei Qing, Shao Xuecheng
IF：
2.3890
Publish_to：
ANTI-CANCER DRUGS
PMID：
36136988
Roles of calpain in the apoptosis of Eimeria tenella host cells at the middle and late developmental stages
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Author：
Cui Xiao-Zhen, Zheng Ming-Xue, Yang Shi-Yu, Bai Rui, Zhang Li
IF：
2.3830
Publish_to：
PARASITOLOGY RESEARCH
PMID：
35412077
MiR-21-5p inhibition attenuates Warburg effect and stemness maintenance in osteosarcoma cells via inactivation of Wnt/β-catenin signaling
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Author：
Ziyan Wu, Zhong Zhou, Weiguo Zhang, Yi Yu
IF：
2.1490
Publish_to：
ACTA BIOCHIMICA POLONICA
PMID：
34694765
Isolation, characterization and differentiation of dermal papilla cells from Small-tail Han sheep
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Author：
Xinhui Luo, Jianqiang Liu, Pengju Zhang, Yongsheng Yu, Bin Wu, Qi Jia, Yanguang Liu, Cheng Xiao, Yang Cao, Haiguo Jin, Lichun Zhang
IF：
2.1410
Publish_to：
ANIMAL BIOTECHNOLOGY
PMID：
36542538
LncIMF1 Promotes Adipogenesis of Porcine Intramuscular Preadipocyte by Sponging miR-187
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Author：
Feng Ming, Yi Xudong, Zhang Ziyi, Zhu Jiahua, Yu He, Ming Lianxi, Pang Weijun
IF：
2.1000
Publish_to：
BIOCHEMICAL GENETICS
PMID：
39961961
Microarray analysis of long non-coding RNAs related to osteogenic differentiation of human dental pulp stem cells
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Author：
Xinyu Hao, Dongfang Li, Dongjiao Zhang, Linglu Jia
IF：
2.0800
Publish_to：
Journal of Dental Sciences
PMID：
35756759
Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/β-catenin signaling pathway
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Author：
Tongke Sun, Dan Ma, Yang Song, Jing Hu, Ziqing Yang, Xu Wang, Jun Zhang
IF：
1.4000
Publish_to：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
PMID：
39932304
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