Discovery of a potent and highly selective inhibitor of SIRT6 against pancreatic cancer metastasis in vivo
点击查看 >>
Author：
Xinyuan Xu, Qian Zhang, Xufeng Wang, Jing Jin, Chengwei Wu, Li Feng, Xiuyan Yang, Mingzhu Zhao, Yingyi Chen, Shaoyong Lu, Zhen Zheng, Xiaobing Lan, Yi Wang, Yan Zheng, Xuefeng Lu, Qiufen Zhang, Jian Zhang
Publish_to：
Acta Pharmaceutica Sinica B
Distinct Species-Specific and Toxigenic Metabolic Profiles for 6PPD and 6PPD Quinone by P450 Enzymes: Insights from In Vitro and In Silico Studies
点击查看 >>
Author：
Zehua Song, Xiaomei Yu, Minghua Zhu, Zimeng Wu, Zhiqiang Fu, Jingwen Chen
Publish_to：
ENVIRONMENTAL SCIENCE & TECHNOLOGY
Strengthening the Combinational Immunotherapy from Modulating the Tumor Inflammatory Environment via Hypoxia-Responsive Nanogels
点击查看 >>
Author：
Wenhe Luo, Yanqiao Zeng, Qingle Song, Yu Wang, Feng Yuan, Qi Li, Yingnan Liu, Su Li, Nahar Jannatun, Guofang Zhang, Yang Li
Publish_to：
Advanced Healthcare Materials
A nanotheranostics with hypoxia-switchable fluorescence and photothermal effect for hypoxia imaging-guided immunosuppressive tumor microenvironment modulation
点击查看 >>
Author：
Xudong Li, Xianbin Sun, Ya Wang, Haijun Chen, Yu Gao
Publish_to：
JOURNAL OF COLLOID AND INTERFACE SCIENCE
A novel investigated method for decoupling adsorption and degradation effect on AFB1 based on isotope tracing and NMR analysis
点击查看 >>
Author：
Wan Zhang, Jun Wang, Jianpeng Dou, Tiantian Li, Hujun Liu, Xiaojiao Chang, Shengfeng Qian, Langao Lv, Wenfu Wu, Changpo Sun
Publish_to：
FOOD CHEMISTRY
A novel strategy for detoxification of deoxynivalenol via modification of both toxic groups
点击查看 >>
Author：
Bingqian Hou, Yongchang Xu, Dawei Wang, Chunmei Dong, Fangfang Yan, Xinxin Cheng, Silong Sun, Cunyao Bo, Zhangwei Liu, Yao Qin, Hongwei Wang, Lingrang Kong
Publish_to：
FOOD CHEMISTRY
Evolution of the biosynthetic pathways of terpene scent compounds in roses
点击查看 >>
Author：
Junzhong Shang, Dedang Feng, Heng Liu, Lintao Niu, Runhui Li, Yajun Li, Mengxi Chen, Ao Li, Zhenhua Liu, Yanhong He, Xiang Gao, Hongying Jian, Changquan Wang, Kaixue Tang, Manzhu Bao, Jihua Wang, Shuhua Yang, Huijun Yan, Guogui Ning
Publish_to：
CURRENT BIOLOGY
Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin
点击查看 >>
Author：
Longhai Dai, Hao Li, Jian-Wen Huang, Yumei Hu, Min He, Yu Yang, Jian Min, Rey-Ting Guo, Chun-Chi Chen
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Selenium nanoparticle rapidly synthesized by a novel highly selenite-tolerant strain Proteus penneri LAB-1
点击查看 >>
Author：
Mingshi Wang, Daihua Jiang, Xuejiao Huang
Mechanism-Based Inactivation of CYP2D6 by Phellopterin and Related Drug每Drug Interaction with Metoprolol
点击查看 >>
Author：
Zihao Cheng, Yan He, Yu Chen, Guode Zhao, Ying Liu, Jingyu Zhang, Ximei Li, Guangyun Ran, Qing Zhang, Ying Peng, Weiwei Li, Jiang Zheng
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Mechanistic study of bergamottin-induced inactivation of CYP2C9
点击查看 >>
Author：
Ying Liu, Shiyu Zhang, Tingting Jiang, Rong Tan, Yao Fu, Xiaojing Yang, Bowen Gong, Ying Zou, Weiwei Li, Jiang Zheng
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
Discovery of potent thiazolidin-4-one sulfone derivatives for inhibition of proliferation of osteosarcoma in vitro and in vivo
点击查看 >>
Author：
Xuwen Chen, Zhengli Luo, Zongjing Hu, Donghui Sun, YingYing He, Jiani Lu, Lili Chen, Shunying Liu
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Phase I Metabolism of Pterostilbene, a Dietary Resveratrol Derivative: Metabolite Identification, Species Differences, Isozyme Contribution, and Further Bioactivation
点击查看 >>
Author：
Ying Li, Changcheng Sun, Yutian Zhang, Xiang Chen, Haoyan Huang, Luyao Han, Han Xing, Di Zhao, Xijing Chen, Yongjie Zhang
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2,3,5,4′-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, a mechanism-based inactivator of CYP2C19 and CYP3A4, potentiates hepatic protein adduction and hepatotoxicity induced by emodin in vivo
点击查看 >>
Author：
Xu Wang, Lingwen Dong, Guode Zhao, Weiwei Li, Ying Peng, Jiang Zheng
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
Enzymatic Verification and Comparative Analysis of Carrageenan Metabolism Pathways in Marine Bacterium Flavobacterium algicola
点击查看 >>
Author：
Chengcheng Jiang, Hong Jiang, Tianyu Zhang, Zewei Lu, Xiangzhao Mao
Publish_to：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Rapid multichannel fluorescent probe assay for CYP450 inhibition screening and drug interaction monitoring
点击查看 >>
Author：
Yingchang Song, Jiayu Zeng, Jianglan Long, Aiting Wang, Kuan Chen, Jia'an Qin, Dan Yan
Publish_to：
MICROCHEMICAL JOURNAL
Enhancement of tolerance against flonicamid in Solenopsis invicta (Hymenoptera: Formicidae) through overexpression of CYP6A14
点击查看 >>
Author：
Tian-yi Zhang, Chang-wei Gong, Jian Pu, An-chun Peng, Xu-yang Li, Yu-meng Wang, Xue-gui Wang
Publish_to：
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
Elucidation of the relationship between evodiamine-induced liver injury and CYP3A4-mediated metabolic activation by UPLC-MS/MS analysis
点击查看 >>
Author：
Peng Ting, Rao Jinqiu, Zhang Tingting, Wang Yuan, Li Na, Gao Qing, Feng Xinchi, Song Zhaohui, Wang Kai, Qiu Feng
Publish_to：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo
点击查看 >>
Author：
Haifeng Zhang, Na Gao, Xin Tian, Tingting Liu, Yan
Publish_to：
Scientific Reports 5, Article number: 17671 (2015)
Transcriptome Analysis of Stephania yunnanensis and Functional Validation of CYP80s Involved in Benzylisoquinoline Alkaloid Biosynthesis
点击查看 >>
Author：
Wenlong Shi, Qishuang Li, Xinyi Li, Linglong Luo, Jingyi Gan, Ying Ma, Jian Wang, Tong Chen, Yifeng Zhang, Ping Su, Xiaohui Ma, Juan Guo, Luqi Huang
The synergistic effect of sea cucumber saponins and caffeine on preventing obesity in high-fat diet-fed mice by extending the action duration of caffeine
点击查看 >>
Author：
Ying-Cai Zhao, Le-Ping Li, Xiao-Yue Li, Cheng-Cheng Wang, Jin-Yue Yang, Chang-Hu Xue, Yu-Ming Wang, Tian-Tian Zhang
Publish_to：
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
Cost-effective whole-cell biosynthesis of ursodeoxycholic acid using engineered Escherichia coli with a multienzyme cascade
点击查看 >>
Author：
Xue Zhang, Jiagang Xin, Mengyu Liu, Yue Zhang, Haoni Luan, Wei Feng, Fei Wang, Wei Xu, Peng Song
Publish_to：
Frontiers in Microbiology
Identification of metabolites of Ginkgolide B in vivo and in vitro using ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
点击查看 >>
Author：
Xiaowei Zhang, Xinpeng Diao, Luya Li, Yuqian Zhang, Man Liao, Guohua Zhang, Lantong Zhang
Publish_to：
JOURNAL OF SEPARATION SCIENCE
Protection of schisantherin A against dictamnine-induced hepatotoxicity: Pharmacokinetic insights
点击查看 >>
Author：
Xiaojin Chang, Guangyao Li, Bufan Yang, Dongju Lin
Publish_to：
JOURNAL OF APPLIED TOXICOLOGY
Metabolic profile and tissue distribution of Humantenirine, an oxindole alkaloid from Gelsemium, after oral administration in rats
点击查看 >>
Author：
Xue-Jia Qi, Meng-Ting Zuo, Si-Juan Huang, Xiao Ma, Zi-Yuan Wang, Zhao-Ying Liu
Publish_to：
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
In vitro impacts of polystyrene microplastics and environmental pollutants on ethoxyresorufin-O-deethylase and glutathione S-transferase activity in Mossambica tilapia
点击查看 >>
Author：
Yan Yin, Haiyan Wang, Guijing Ouyang, Daxiong Han
Publish_to：
TOXICOLOGY IN VITRO
Improved preclinical drug metabolism and pharmacokinetics of pibothiadine (HEC121210), a novel hepatitis B virus capsid assembly modulator
点击查看 >>
Author：
Ming Li, Xingguo Yan, Li Zhang, Xinchang Liu, Yayi Liu, Qian Wang, Jing Li
中文
英语
京公网安备 11011202000391号