中文
英语
产品简介
| 中文名称 | 改良天狼星红染色试剂盒 |
| 英文名称 | Modified Sirius Red Stain Kit（No Picric Acid） |
| 储存条件 | RT，避光保存，有效期1年。 |
| 规格 | 2*50ml 2*500ml |
| 单位 | 盒 |
胶原纤维(Collagen Fiber)是结缔组织中分布最广含量最多的一种纤维，广泛分布于各种脏器，其中Ⅰ型胶原纤维主要是骨、皮肤、肌腱；Ⅱ型胶原纤维主要是软骨胶原；Ⅲ型胶原纤维主要在胚胎组织、成人血管、胃肠道；Ⅳ型胶原纤维主要在基膜中。天狼星红与其衬染液都是强酸性染料，易与胶原分子中的碱性基团结合，吸附牢固。偏振光镜检查，胶原纤维有正的单轴双折射光的属性，与天狼星红复合染色液结合后，可增强双折射，提高分辨率，从而区分不同类型的胶原纤维。
改良天狼星红染色试剂盒主要由铁苏木素染色液和天狼星红染色液组成，不含苦味酸。主要用于各种组织病变时对胶原纤维异常或纤维增生的研究中，在普通光学显微镜下心脏血管等组织的胶原纤维被染成红色，在偏振光镜下对各种纤维化病变的分型和分级研究有一定的帮助作用。采用免疫组化技术也可显示Ⅰ、Ⅲ型胶原纤维，但所用抗体昂贵，操作费时，而采用天狼星红染色法试剂便宜，操作简单。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
实验内容 肝癌石蜡切片-偏光显微镜结果胶原纤维在偏光镜下呈现双折光，Ⅰ型胶原纤维呈强橙黄色或亮红色，Ⅲ型胶原纤维呈绿色。
肝癌石蜡切片-光学显微镜结果胶原纤维呈红色，背景呈黄色，细胞核呈红褐色到黑色。
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Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress
点击查看 >>
Author：
Wenji Ren, Zixu Wang, Jing Cao, Yulan Dong, Tuanjie Wang, Yaoxing Chen
IF：
7.6750
Publish_to：
Antioxidants
PMID：
37237884
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen
点击查看 >>
Author：
Lingxi Chen, Yingjun Su, Bin Yin, Shu Li, Xialin Cheng, Yan He, Chiyu Jia
IF：
7.5900
Publish_to：
JOURNAL OF INVESTIGATIVE DERMATOLOGY
PMID：
35176288
One-step in situ deposition of phytic acid–metal coordination complexes for combined Porphyromonas gingivalis infection prevention and osteogenic induction
点击查看 >>
Author：
Ning Gan, Wei Qin, Chunlei Zhang, Ting Jiao
IF：
7.5710
Publish_to：
Journal of Materials Chemistry B
PMID：
35535980
Extracellular matrix remodelling and stiffening contributes to tumorigenesis of salivary carcinoma ex pleomorphic adenoma——A study based on patient-derived organoids
点击查看 >>
Author：
Chen Wanling, Gu Ting, Chen Qianqian, Qu Chuxiang, Zhang Chunye, Hu Yuhua, Xia Ronghui, Zhang Ying, Wang Min, Huang Xinyi, Li Jiang, Shi Chaoji, Tian Zhen
IF：
7.5000
Publish_to：
Cell and Bioscience
PMID：
37393249
Activation of α7nAChR preserves intestinal barrier integrity by enhancing the HO-1 / STAT3 signaling to inhibit NF-κB activation in mice
点击查看 >>
Author：
Wei Lei, Changcheng Zhao, Jiasen Sun, Yanling Jin, Zhijun Duan
IF：
7.4190
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
36068769
27-Hydroxycholesterol induces liver fibrosis via down-regulation of trimethylation of histone H3 at lysine 27 by activating oxidative stress; effect of nutrient interventions
点击查看 >>
Author：
Kailin Jiao, Keke Yang, Jie Wang, Yifan Ni, Chunyan Hu, Jiao liu, Ming Zhou, Jin Zheng, Zhong Li
IF：
7.4000
Publish_to：
FREE RADICAL BIOLOGY AND MEDICINE
PMID：
38056577
Resveratrol prevents Drp1-mediated mitochondrial fission in the diabetic kidney through the PDE4D/PKA pathway
点击查看 >>
Author：
Xia Zhu, Zongli Deng, Yanjuan Cao, Zihui Zhou, Wen Sun, Chang Liu, Siwen Fan, Xiao-Xing Yin
IF：
7.2000
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
37767771
Hyperphosphorylation of EGFR/ERK signaling facilitates long-term arsenite-induced hepatocytes epithelial-mesenchymal transition and liver fibrosis in sprague-dawley rats
点击查看 >>
Author：
Dapeng Wang, Huifen Xu, Lili Fan, Wenli Ruan, Qian Song, Heng Diao, Rui He, Ying Jin
IF：
7.1290
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
36508792
Adipose-derived stem cells apoptosis rejuvenate radiation-impaired skin in mice via remodeling and rearranging dermal collagens matrix
点击查看 >>
Author：
Zhu Yufan, Liu Xu, Chen Xihang, Liao Yunjun
IF：
7.1000
Publish_to：
Stem Cell Research & Therapy
PMID：
39334464
Celecoxib, Beyond Anti-inflammation, Alleviates Tendon-Derived Stem Cell Senescence in Degenerative Rotator Cuff Tendinopathy
点击查看 >>
Author：
Zhuochang Cai, Yao Zhang, Shen Liu, Xudong Liu
IF：
7.0100
Publish_to：
AMERICAN JOURNAL OF SPORTS MEDICINE
PMID：
35666137
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses
点击查看 >>
Author：
Shuni Duan, Xin Li, Junsong Han, Yang Yang, Ranyi Luo, Yajie Cai, Xiaojiaoyang Li, Qi Zheng, Jincheng Guo, Runping Liu
IF：
7.0000
Publish_to：
Antioxidants
PMID：
38539789
SIRT4 protects against intestinal fibrosis by facilitating GLS1 degradation
点击查看 >>
Author：
Xinru Xue, Xi Zeng, Xiaoqian Wu, Kexin Mu, Yue Dai, Zhifeng Wei
IF：
6.9000
Publish_to：
MATRIX BIOLOGY
PMID：
37541633
hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B
点击查看 >>
Author：
Ma Jing, Li Yi, Chen Mengxuan, Wang Weihang, Zhao Qiqian, He Bo, Zhang Min, Jiang Yongfang
IF：
6.8190
Publish_to：
CELL BIOLOGY AND TOXICOLOGY
PMID：
35484432
Triclosan induces liver injury in long-life exposed mice via activation of TLR4/NF-κB/NLRP3 pathway
点击查看 >>
Author：
Yuxuan Peng, He Cui, Chang Shu, Ziyun Wei, Xiao Ni, Jieyu Liu
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38377781
Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea
点击查看 >>
Author：
Xiaoxiao Yang, Zhigang Liu, Mengyuan Fang, Tingfeng Zou, Zhen Zhang, Xianshe Meng, Tianxiang Wang, Huawen Meng, Yuanli Chen, Yajun Duan, Qingshan Li
IF：
6.7000
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
37406380
Glycyrrhizic acid alleviates liver fibrosis in vitro and in vivo via activating CUGBP1-mediated IFN-γ/STAT1/Smad7 pathway
点击查看 >>
Author：
Manman Guo, Zhongda Wang, Jinya Dai, Haizhen Fan, Ningning Yuan, Liming Gao, Huiping Peng, Xiaolan Cheng
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
36805480
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation
点击查看 >>
Author：
Feng Shu, Xie Xingming, Li Jianchao, Xu Xu, Chen Chaochun, Zou Gaoliang, Lin Guoyuan, Huang Tao, Hu Ruihan, Ran Tao, Han Lu, Zhang Qingxiu, Li Yuanqingxiao, Zhao Xueke
IF：
6.6000
Publish_to：
Hepatology International
PMID：
38172440
Resveratrol Confers Vascular Protection by Suppressing TLR4/Syk/NLRP3 Signaling in Oxidized Low-Density Lipoprotein-Activated Platelets
点击查看 >>
Author：
Yun Xue, Huilian Chen, Shenghao Zhang, Li Bao, Beidong Chen, Huan Gong, Yanyang Zhao, Ruomei Qi
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
33728029
QiShenYiQi ameliorates salt-induced hypertensive nephropathy by balancing ADRA1D and SIK1 expression in Dahl salt-sensitive rats
点击查看 >>
Author：
Hongxia Du, Guangxu Xiao, Zhifeng Xue, Zhixiong Li, Shuang He, Xiaoli Du, Zhengchan Zhou, Linghua Cao, Yule Wang, Jian Yang, Xiaoying Wang, Yan Zhu
IF：
6.5300
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
34328102
Resveratrol ameliorates liver fibrosis induced by nonpathogenic Staphylococcus in BALB/c mice through inhibiting its growth
点击查看 >>
Author：
Li Zhiqin, Dong Jianxia, Wang Meng, Yan Jingya, Hu Yushu, Liu Yang, Pan Yajie, Li Hua
IF：
6.3760
Publish_to：
MOLECULAR MEDICINE
PMID：
35508992
Characterization and evaluation of a femtosecond laser-induced osseointegration and an anti-inflammatory structure generated on a titanium alloy
点击查看 >>
Author：
Liu Yang, Rui Zhongying, Cheng Wei, Song Licheng, Xu Yunqiang, Li Ruixin, Zhang Xizheng
IF：
6.3530
Publish_to：
Regenerative Biomaterials
PMID：
33738120
Ginsenoside Rd,a natural production for attenuating fibrogenesis and inflammation in hepatic fibrosis by regulating the ERRα-mediated P2X7r pathway
点击查看 >>
Author：
Long Cui, Yu-Jing Tan, Shi-Qi Xu, Bo-Feng Qin, Meng-Xue Xiu, Xue Zhang, Li-Qiang Shi, Hai-Ming Sun, Jian Song
IF：
6.3170
Publish_to：
Food & Function
PMID：
37249244
3D Extracellular Matrix Regulates the Activity of T Cells and Cancer Associated Fibroblasts in Breast Cancer
点击查看 >>
Author：
Gao Huan, Tian Qi, Zhu Lizhe, Feng Jinteng, Zhou Yan, Yang Jin
IF：
6.2440
Publish_to：
Frontiers in Oncology
PMID：
34956886
The Reduction of Uromodulin,Complement Factor H,and Their Interaction Is Associated with Acute Kidney Injury to Chronic Kidney Disease Transition in a Four-Time Cisplatin-Injected Rat Model
点击查看 >>
Author：
Zheyu Xing, Kunjing Gong, Nan Hu, Yuqing Chen
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
37047611
OTUD1 promotes isoprenaline- and myocardial infarction-induced heart failure by targeting PDE5A in cardiomyocytes
点击查看 >>
Author：
Qinyan Wang, Shiqi Liang, Jinfu Qian, Jiachen Xu, Qingsong Zheng, Mengyang Wang, Xiaochen Guo, Julian Min, Gaojun Wu, Zaishou Zhuang, Wu Luo, Guang Liang
IF：
6.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
38185350
Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration
点击查看 >>
Author：
Meng-chen Qin, Jun-jie Li, Yan-tao Zheng, Yun-jia Li, Yu-xue Zhang, Rou-xuan Ou, Wei-yi He, Jia-min Zhao, Su-tong Liu, Ming-hao Liu, Hai-yan Lin, Lei Gao
IF：
6.1000
Publish_to：
Food & Function
PMID：
37930368
Astragaloside IV Blunts Epithelial–Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy
点击查看 >>
Author：
Dong Li, Yuzhe Liu, Quancao Zhan, Yan Zeng, Ze Peng, Qifeng He, Qi Tan, Wenfu Cao, Shang Wang, Jianwei Wang
IF：
6.0000
Publish_to：
Cells
PMID：
37443810
Quercetin Attenuates Podocyte Apoptosis of Diabetic Nephropathy Through Targeting EGFR Signaling
点击查看 >>
Author：
Liu Yiqi, Li Yuan, Xu Liu, Shi Jiasen, Yu Xiujuan, Wang Xue, Li Xizhi, Jiang Hong, Yang Tingting, Yin Xiaoxing, Du Lei, Lu Qian
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35069207
Single-cell sequencing reveals the transcriptional alternations of 17β-estradiol suppressing primordial follicle formation in neonatal mouse ovaries
点击查看 >>
Author：
Yutong Yan, Hui Zhang, Rui Xu, Linglin Luo, Lu Yin, Hao Wu, Yiqian Zhang, Chan Li, Sihai Lu, Yaju Tang, Xiaoe Zhao, Menghao Pan, Qiang Wei, Sha Peng, Baohua Ma
IF：
5.9000
Publish_to：
CELL PROLIFERATION
PMID：
38988058
Ginsenoside Rg2 Ameliorating CDAHFD-Induced Hepatic Fibrosis by Regulating AKT/mTOR-Mediated Autophagy
点击查看 >>
Author：
Ziwei He, Siyu Chen, Tingting Pan, Ao Li, Kangyu Wang, Zhuofeng Lin, Wei Liu, Yi Wang, Yanfang Wang
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
35104139
Sarsasapogenin restores podocyte autophagy in diabetic nephropathy by targeting GSK3β signaling pathway
点击查看 >>
Author：
Xi-zhi Li, Hong Jiang, Liu Xu, Yi-qi Liu, Jia-wei Tang, Jia-sen Shi, Xiu-juan Yu, Xue Wang, Lei Du, Qian Lu, Cheng-lin Li, Yao-wu Liu, Xiao-xing Yin
IF：
5.8580
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
34252407
Maternal nicotine exposure aggravates metabolic associated fatty liver disease via PI3K/Akt signaling in adult offspring mice
点击查看 >>
Author：
Shu-Jing Huang, Shu-qiang Chen, Yan Lin, Hong-Yi Yang, Jing Ran, Fang-Fang Yan, Mei Huang, Xian-Lan Liu, Long-Cheng Hong, Xiao-Dong Zhang, Guo-Rong Lyu, Zhan-Xiang Wang, Yi-Ming Su
IF：
5.8280
Publish_to：
LIVER INTERNATIONAL
PMID：
33894105
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation
点击查看 >>
Author：
Kai Song, He Sun, Bin Tu, Yang Zhou, Li-Chan Lin, Zhi-Yan Liu, Rui Li, Jing-Jing Yang, Ye Zhang, Jian-Yuan Zhao, Hui Tao
IF：
5.8000
Publish_to：
iScience
PMID：
37810250
Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype
点击查看 >>
Author：
Min Zhang, Caiping Wang, Rongning Wang, Jiean Xu, Zhefeng Wang, Jianlong Yan, Yongfeng Cai, Liangping Li, Yuqing Huo, Shaohong Dong
IF：
5.7630
Publish_to：
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
PMID：
36473288
Triptolide attenuates CCL4-induced liver fibrosis by regulating the differentiation of CD4+ T cells in mice
点击查看 >>
Author：
Shiyuan Jiang, Jing Feng, Yanling Jiang, Zhihao Lu, Jingwei Kong, Xueming Li, Hui Lian, Fang Zhang, Yu Li, Jian Li
IF：
5.6000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37956491
Mechanical loading on cell-free polymer composite scaffold enhances in situ regeneration of fully functional Achilles tendon in a rabbit model
点击查看 >>
Author：
Wenbo Wang, Xunxun Lin, Tian Tu, Zheng Guo, Zhenfeng Song, Yongkang Jiang, Boya Zhou, Dong Lei, Xiansong Wang, Wenjie Zhang, Guangdong Zhou, Bingcheng Yi, Peihua Zhang, Wei Liu
IF：
5.5000
Publish_to：
Biomaterials Advances
PMID：
38972278
Hepatoprotective efficacy and interventional mechanism of JianPi LiShi YangGan formula in acute-on-chronic liver failure
点击查看 >>
Author：
Jing Li, Qi Huang, Wenfeng Ma, JinYu Yi, Xin Zhong, Rui Hu, Jialing Sun, MengQing Ma, Minling Lv, Zhiyi Han, Wei Zhang, Wenxing Feng, Xinfeng Sun, Xiaozhou Zhou
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
37422102
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis
点击查看 >>
Author：
Shihong Zheng, Peichang Cao, Zequn Yin, Xuerui Wang, Yuanli Chen, Maoyun Yu, Baocai Xu, Chenzhong Liao, Yajun Duan, Shuang Zhang, Jihong Han, Xiaoxiao Yang
IF：
5.3960
Publish_to：
Food & Function
PMID：
33620063
Focal adhesion kinase-related non-kinase ameliorates liver fibrosis by inhibiting aerobic glycolysis via the FAK/Ras/c-myc/ENO1 pathway
点击查看 >>
Author：
Tao Huang, Yuan-Qing-Xiao Li, Ming-Yu Zhou, Rui-Han Hu, Gao-Liang Zou, Jian-Chao Li, Shu Feng, Yong-Mei Liu, Chang-Qin Xin, Xue-Ke Zhao
IF：
5.3740
Publish_to：
WORLD JOURNAL OF GASTROENTEROLOGY
PMID：
35125823
N-Acetyl-l-tryptophan inhibits CCl4-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal
点击查看 >>
Author：
Tingting Ma, Huanli Cheng, Tongxi Li, Yifan Chen, Tianying Cai, Junjie Bai, Ziming Wu, Xianming Xia, Tiancheng Liang, Yichao Du, Wenguang Fu
IF：
5.3070
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
35667255
10-Hydroxy-2-decenoic acid attenuates nonalcoholic fatty liver disease by activating AMPK-α signaling pathway
点击查看 >>
Author：
Minyi Tang, Xinzi Wang, Shuai Wang, Chaofeng Xing, Qihua Xu, Yunping Mu, Xiaoli Wu, Allan Zijian Zhao, Fanghong Li
IF：
5.3000
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
39581533
Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells
点击查看 >>
Author：
Yan Ranran, Bai Zhenzhong, Ge Ri-li
IF：
5.2000
Publish_to：
Frontiers in Endocrinology
PMID：
38501098
Postnatal deletion of Bmal1 in mice protects against obstructive renal fibrosis via suppressing Gli2 transcription
点击查看 >>
Author：
Jiayang Zhang, Chengcheng Liu, Qing Liang, Feng Zheng, Youfei Guan, Guangrui Yang, Lihong Chen
IF：
5.1920
Publish_to：
FASEB JOURNAL
PMID：
33813752
MicroRNA-34b-5p binds enhancer of zeste 2 to inhibit milk fat globule-EGF factor 8 expression, affecting liver fibrosis
点击查看 >>
Author：
Ma Jing, Liu Qiyao, Chen Mengxuan, He Bo, Li Yi, Zhang Min, Jiang Yongfang
IF：
5.0800
Publish_to：
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
PMID：
36138295
Oroxin B improves metabolic-associated fatty liver disease by alleviating gut microbiota dysbiosis in a high-fat diet-induced rat model
点击查看 >>
Author：
Yuhong Huang, Chao Wang, Meng Wang, Tao Xiong, Xinhua Song, Wenlong Sun, Jingda Li
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
37179040
Construction of spider silk protein small-caliber tissue engineering vascular grafts based on dynamic culture and its performance evaluation
点击查看 >>
Author：
Lulu Sun, Xiafei Li, Tuo Yang, Tian Lu, Pengchong Du, Changqin Jing, Zhigang Chen, Fei Lin, Guoan Zhao, Liang Zhao
IF：
4.8540
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
36129207
HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression
点击查看 >>
Author：
Jing Sun, Xiuli Jin, Xinhe Zhang, Birong Zhang
IF：
4.8000
Publish_to：
CELLULAR SIGNALLING
PMID：
37268162
Poly-ε-caprolactone/Whitlockite Electrospun Bionic Membrane with an Osteogenic–Angiogenic Coupling Effect for Periosteal Regeneration
点击查看 >>
Author：
Xiangke Zhang, Wenbin Liu, Jiawei Liu, Yihe Hu, Honglian Dai
IF：
4.7490
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
34148343
Terbuthylazine exposure induces innate immune response and inflammation through activating cGAS-STING/NF-κB pathway in myocardium of broiler chicken (Gallus gallus)
点击查看 >>
Author：
Haoye Li, Qingwen Yang, Haitong Wu, Jianying Guo, Zhaoxin Tang, Jianzhao Liao
IF：
4.7000
Publish_to：
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
PMID：
38072555
Knockout of Shcbp1 sensitizes immunotherapy by regulating α-SMA positive cancer-associated fibroblasts
点击查看 >>
Author：
Qianlin Gu, Zhijian Ma, Qiaoyan Wang, Yiwei Dai, Wengui Shi, Zuoyi Jiao
IF：
4.6000
Publish_to：
MOLECULAR CARCINOGENESIS
PMID：
38169303
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis
点击查看 >>
Author：
Qi Wenchuan, Li Xiang, Ren Yanrong, Liu Xueying, Fu Hongjuan, Wang Xiao, Li Xiao, Xiong Jian, Zheng Qianhua, Cai Dingjun, Liang Fanrong
IF：
4.5460
Publish_to：
Chinese Medicine
PMID：
35578250
Exercise ameliorating myocardial injury in type 2 diabetic rats by inhibiting excessive mitochondrial fission involving increased irisin expression and AMP-activated protein kinase phosphorylation
点击查看 >>
Author：
Bin Wang, Chen Zhao, Yuanxin Wang, Xin Tian, Junjie Lin, Baishu Zhu, Yalan Zhou, Xin Zhang, Nan Li, Yu Sun, Haocheng Xu, Renqing Zhao
IF：
4.5000
Publish_to：
Journal of Diabetes
PMID：
37721125
A Pilot Metabolomic Study on Myocardial Injury Caused by Chronic Alcohol Consumption—Alcoholic Cardiomyopathy
点击查看 >>
Author：
Zhipeng Cao, Tianqi Wang, Wei Xia, Baoli Zhu, Meihui Tian, Rui Zhao, Dawei Guan
IF：
4.4120
Publish_to：
MOLECULES
PMID：
33918931
Dynamic changes of enhancer and super enhancer landscape in degenerated nucleus pulposus cells
点击查看 >>
Author：
Guowang Li, Yuxiang Kang, Xiangling Feng, Guohua Wang, Yue Yuan, Zhenhua Li, Lilong Du, Baoshan Xu
IF：
4.4000
Publish_to：
Life Science Alliance
PMID：
37012048
Gallium (Ga)–strontium (Sr) layered double hydroxide composite coating on titanium substrates for enhanced osteogenic and antibacterial abilities
点击查看 >>
Author：
Kai Li, Hongchuan Tian, Ai Guo, Liguo Jin, Weizhen Chen, Bailong Tao
IF：
4.3960
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
34323363
Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis
点击查看 >>
Author：
Cai Chengyuan, Zeng Danning, Gao Qing, Ma Lei, Zeng Bohang, Zhou Yi, Wang He
IF：
4.3800
Publish_to：
Scientific Reports
PMID：
34183746
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts
点击查看 >>
Author：
Yifei Wang, Yaqin Zhang, Bing Lu, Jianbo Xi, Dickson Kofi Wiredu Ocansey, Fei Mao, Donglin Hao, Yongmin Yan
IF：
4.3000
Publish_to：
Stem Cells International
PMID：
36845967
PiRNA CFAPIR inhibits cardiac fibrosis by regulating the muscleblind-like protein MBNL2
点击查看 >>
Author：
Lin Lv, Keying Yuan, Jiahao Li, Jing Lu, Qi Zhao, Hongyan Wang, Qiuyu Chen, Xinyu Dong, Siqi Sheng, Mingyu Liu, Yuanqi Shi, Hongquan Jiang, Zengxiang Dong
IF：
4.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
39122223
Protective effects and regulatory mechanisms of Shen-shuai-yi recipe on renal fibrosis in unilateral ureteral obstruction-induced mice
点击查看 >>
Author：
Ping-lan Lin, Tao-tao Weng, Lian-xiang Duan, Lin-zhang Zhang, Xia Wei, Sheng-lan Qi, Jia-wen You, Yu Cao, Guang-bo Ge, Wei Liu, Xiao-li He, Jing Hu
IF：
4.0000
Publish_to：
Heliyon
PMID：
37483732
2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway
点击查看 >>
Author：
Chen Zhengjie, Zheng Liangyu, Chen Gang
IF：
3.9470
Publish_to：
CARDIOVASCULAR DRUGS AND THERAPY
PMID：
35305183
Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway
点击查看 >>
Author：
Xuesong Su, Guangyu Zhou, Mi Tian, Si Wu, Yanqiu Wang
IF：
3.9050
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
34181940
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease
点击查看 >>
Author：
Dan Wang, Ling Yin, Rongyu Chen, Wanlin Tan, Luqun Liang, Jiayi Xiang, Huifang Zhang, Xingcheng Zhou, Huaqing Deng, Bing Guo, Yuanyuan Wang
IF：
3.9000
Publish_to：
Frontiers in Medicine
PMID：
36760880
Inhibition of MEG3 ameliorates cardiomyocyte apoptosis and autophagy by regulating the expression of miRNA-129-5p in a mouse model of heart failure
点击查看 >>
Author：
Shan Mi, Feng Huang, Mingli Jiao, Zhuang Qian, Mingming Han, Zheng Miao, Heqin Zhan
IF：
3.8000
Publish_to：
REDOX REPORT
PMID：
37338021
Mimicking osteochondral interface using pre-differentiated BMSCs/fibrous mesh complexes to promote tissue regeneration
点击查看 >>
Author：
Lei Fu, Wenwen Zhao, Liwen Zhang, Chenyuan Gao, Xin Zhang, Xiaoping Yang, Qing Cai
IF：
3.6820
Publish_to：
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
PMID：
35765951
Recruitment or activation of mast cells in the liver aggravates the accumulation of fibrosis in carbon tetrachloride-induced liver injury
点击查看 >>
Author：
Mingkang Zhang, Jinru Yang, Yufan Yuan, Yan Zhou, Yazhi Wang, Ruirui Cui, Yimai Maliu, Fen Xu, Xin’an Wu
IF：
3.6000
Publish_to：
MOLECULAR IMMUNOLOGY
PMID：
38626622
Liproxstatin-1 alleviates bleomycin-induced alveolar epithelial cells injury and mice pulmonary fibrosis via attenuating inflammation, reshaping redox equilibrium, and suppressing ROS/p53/α-SMA pathway
点击查看 >>
Author：
Ningning Tao, Kang Li, Jingjing Liu, Guoqing Fan, Tieying Sun
IF：
3.5750
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
33735625
Ginsenoside Rg2 alleviates myocardial fibrosis by regulating TGF-β1/Smad signalling pathway
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Author：
Quanwei Wang, Wenwen Fu, Xiaofeng Yu, Huali Xu, Dayun Sui, Yeling Wang
IF：
3.5030
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
33535854
Synergistic Effects of a Novel Multifunctional Bionic Scaffold and Electrical Stimulation Promote Bone Tissue Regeneration
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Author：
Yingxin Zhang, Huanyan Dai, Xi Li, Zhiyan Wu, Zhimin Xu, Peng Liu, Bing Han
IF：
3.5000
Publish_to：
BIOTECHNOLOGY AND BIOENGINEERING
PMID：
40066628
Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice
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Author：
Min Jia, Wenxue Liu, Keyin Zhang, Zhigang Wang, Ruisha Li, Jun Pan, Jianjun Yang, Dongjin Wang
IF：
3.4000
Publish_to：
Molecular Medicine Reports
PMID：
38275127
Panda Rope Bridge Technique promoted Achilles tendon regeneration in a novel rat tendon defect model
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Author：
Chen Shen, Xianding Sun, Zhi Li, Ruobin Zhang, Junlan Huang, Kaiying Tang, Ting Wang, Yangli Xie, Lin Chen, Mao Nie
IF：
3.3000
Publish_to：
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
PMID：
39342498
A combination of pirfenidone and TGF-β inhibition mitigates cystic echinococcosis-associated hepatic injury
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Author：
Erqiang Wang, Zhenyu Liao, Lianghai Wang, Yuan Liao, Xiaodan Xu, Ping Liu, Xian Wang, Jun Hou, Huijiao Jiang, Xiangwei Wu, Xueling Chen
IF：
3.2340
Publish_to：
PARASITOLOGY
PMID：
33583470
Dapagliflozin alleviates high-fat-induced obesity cardiomyopathy by inhibiting ferroptosis
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Author：
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou
IF：
3.2000
Publish_to：
ESC Heart Failure
PMID：
39523867
Astragaloside IV Alleviates Atorvastatin-Induced Hepatotoxicity via AMPK/SIRT1 Pathway
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Author：
Qin Lili, Wang Yanxia, Liang Yingying, Li Qiang, Xie Xuerong, Zhang Honglian
IF：
3.1000
Publish_to：
PHARMACOLOGY
PMID：
36423574
MAF bZIP Transcription Factor B (MAFB) Protected Against Ovalbumin-Induced Allergic Rhinitis via the Alleviation of Inflammation by Restoring the T Helper (Th) 1/Th2/Th17 Imbalance and Epithelial Barrier Dysfunction
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Author：
Yang Sun, Tiancong Liu, Weiliang Bai
IF：
3.0270
Publish_to：
Journal of Asthma and Allergy
PMID：
35250280
Circulating microRNA‑135a‑3p in serum extracellular vesicles as a potential biological marker of non‑alcoholic fatty liver disease
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Author：
Hemin Jiang, Yu Qian, Ziyang Shen, Yuwei Liu, Yunqiang He, Rui Gao, Min Shen, Shu Chen, Qi Fu, Tao Yang
IF：
2.9520
Publish_to：
Molecular Medicine Reports
PMID：
33955511
Qili Qiangxin capsule attenuates myocardial fibrosis by modulating collagen homeostasis post-infarction in rats
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Author：
Minyan Sun, Chunhua Liu, Kehan Gao, Xingming Xu, Kunhan Chen, Liang Qiu, Xiaomin Wang
IF：
2.9000
Publish_to：
PLoS One
PMID：
39331597
Exogenous PRAS40 reduces KLF4 expression and alleviates hypertrophic scar fibrosis and collagen deposition through inhibiting mTORC1
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Author：
Chao Wang, Duyin Jiang
IF：
2.7000
Publish_to：
BURNS
PMID：
38369439
Ferulic Acid Alleviates Oxidative Stress-Induced Cardiomyocyte Injury by the Regulation of miR-499-5p/p21 Signal Cascade
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Author：
Shenghui Sun, Yang Ruan, Mingjing Yan, Kun Xu, Yao Yang, Tao Shen, Zening Jin
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
34917156
STUB1 increases adiponectin expression by inducing ubiquitination and degradation of NR2F2, thereby reducing hepatic stellate cell activation and alleviating non-alcoholic fatty liver disease
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Author：
Zheng Mao, Jindong Zhao, Fan Cui, Zhen Li, Jinjin Cao, Jingjing Zhou, Mingliang Hou, Zengkun Qian
IF：
2.6000
Publish_to：
TISSUE & CELL
PMID：
38471267
C23 ameliorates carbon tetrachloride-induced liver fibrosis in mice
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Author：
Rong-Xing Tang, Xiao-Jun Xie, Yong Xiong, Su Li, Chen Luo, Yi-Gang Wang
IF：
2.5000
Publish_to：
World Journal of Hepatology
PMID：
39351519
Yin Yang 1 facilitates the activation, inflammation, and extracellular matrix deposition of hepatic stellate cells in hepatic fibrosis
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Author：
Xiao Fu, Xin Luo, Ping Xiao, Ninghong Guo
IF：
2.2000
Publish_to：
PATHOLOGY INTERNATIONAL
PMID：
38353379
High-Speed Centrifugation Efficiently Removes Immunogenic Elements in Osteochondral Allografts
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Author：
Yongsheng Ma, Qitai Lin, Wenming Yang, Yang Liu, Yugang Xing, Zhiyuan Ren, Xueding Wang, Raorao Zhou, Gaige Wu, Pengcui Li, Wangping Duan, Xiaoling Zhang, Xiaochun Wei
IF：
2.1000
Publish_to：
Orthopaedic Surgery
PMID：
38238250
Camk2a suppresses denervated muscle atrophy by maintaining the Ca2+ homeostasis in muscle cells
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Author：
Yanan Zhang, Mingjie Xia, Tianyu Zhao, Qinyang Zhang, Rulin Li, Lei Yang
IF：
1.6000
Publish_to：
CELLULAR AND MOLECULAR BIOLOGY
PMID：
38015546
Freezing Injury in Mouse Masseter Muscle to Establish an Orofacial Muscle Fibrosis Model
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Author：
Xu Cheng, Yixuan Huang, Yanan Li, Jingtao Li, Yan Wang
IF：
1.2000
Publish_to：
Jove-Journal of Visualized Experiments
PMID：
38224092
Puerarin alleviated oxidative stress and ferroptosis during renal fibrosis induced by ischemia/reperfusion injury via TLR4/Nox4 pathway in rats
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Author：
Jian Jun, Wang Dan, Xiong Yufeng, Wang Jingsong, Zheng Qingyuan, Jiang Zhengyu, Zhong Jiacheng, Yang Song, Wang Lei
IF：
1.1000
Publish_to：
Acta Cirurgica Brasileira
PMID：
37556718
The therapeutic potential of PX-478 in a murine model of pelvic organ prolapse
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Author：
Wei-Min Fan, Yu-Qi Yang, Li-Wen Zhang, Xiao-Hui Mei, Ke Sun, Duan-Qing Wu, Ying Yang, Chun-Fang Duan, Jun Ye, Ru-Jun Chen
IF：
0.9000
Publish_to：
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
PMID：
39494634
技术问答
（21）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
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人的组织有哪些可以做天狼猩红染色呢2025-04-08 10:19:05
您好，常规的心、肝、脾、肺、肾、肠都可以做天狼星红染色，具体需要根据实验目的选择合适样本。
50ML的可以染多少人份2025-04-08 10:18:25
您好，按照一张切片染色液用量为300-400ul来算，50ml染色液可以染125-160张切片
可以染脑切片吗，可以染出结果吗2024-12-22 21:21:15
您好，该试剂盒主要用于常规心肝肾等的结缔组织多色染色，区分胶原纤维和肌纤维，脑组织样本不太适用，建议选择免疫组化方式进行胶原蛋白标记。
肾脏组织染色偏红是 什么原因？天狼星红染液需要染多久？2024-12-16 16:33:09
您好，染色偏红可能与染色时间、水洗等因素有关，建议调整染色时间，天狼星红一般染色10min
细胞胶原染色的话要用什么试剂盒2024-11-08 22:15:55
您好，该试剂盒只适用于组织样本类型的胶原纤维染色，我司暂时没有适用于细胞胶原染色的试剂盒