中文
英语
说明书下载
本产品批次间MDA含量会有所不同，实验时需要关注MDA差异，适当调整实验条件。
氧化型低密度脂蛋白
英文名称:Oxidized Low Density Lipoprotein
储存条件:Store at 2-8℃，avoid light and freeze，6 weeks
纯度:98%, is determined agarose gel electrophoresis
产品简介
| 中文名称 | 氧化型低密度脂蛋白 |
| 英文名称 | Oxidized Low Density Lipoprotein |
| 别名 | Ox-LDL;氧化低密度脂蛋白;oxLDL |
| 溶解性 | Buffer containing phosphate-buffered saline at pH 7.4 and 0.2 mM EDTA-Na2. |
| 纯度 | 98%, is determined agarose gel electrophoresis |
| 外观(性状) | Liquid. 0.22 micron membrane filtered, aseptically filled. |
| 储存条件 | Store at 2-8℃，avoid light and freeze，6 weeks |
| 运输条件 | 冷藏运输 |
| 货期 | 5-7个工作日 |
| 背景说明 | Human LDL(which was purified to homogeneity via ultra-centrifugation (1.019-1.063g/cc)) is oxidized using 5μM Cu2SO4（oxidant）in PBS at 37℃ for 20 hours. Oxidation is terminated by adding excess EDTA-Na2. Each lot is analyzed on agarose gel electrophoresis for migration versus LDL. This lot of Ox-LDL migrates 2.0 fold further than the native LDL. This type Oxidized LDL is widely used to investigate lipid metabolism, but not induce cell apoptosis. Apoptosis inducement please choose High Oxidized LDL(Cat#IL2150). |
| 规格 | 2mg |
| 单位 | 瓶 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
Ping X,,et al.Theranostics. 2025 Mar 29;15(10):4785-4807. doi: 10.7150/thno.104179.
Shen X,et al.J Hazard Mater. 2024 Sep 5;476:135048. doi: 10.1016/j.jhazmat.2024.135048.
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Publish_to：
BMC Cardiovascular Disorders
PMID：
33892646
Knockdown of circ_0003204 alleviates oxidative low-density lipoprotein-induced human umbilical vein endothelial cells injury: Circulating RNAs could explain atherosclerosis disease progression
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Author：
Qiuxia Su, Xianhua Dong, Chonghui Tang, Xiaojie Wei, Youguo Hao, Jun Wu
IF：
2.1990
Publish_to：
Open Medicine
PMID：
33869778
Hsa_ circ_0006867 regulates ox-LDL-induced endothelial injury via the miR-499a-3p/ADAM10 axis
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Author：
Hong Ji-Ge, Zheng Hui-Lei, Wang Peng, Huang Ping, Gong Dan-Ping, Zeng Zhi-Yu
IF：
2.1000
Publish_to：
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
PMID：
37694359
MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS
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Author：
Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao
IF：
1.9660
Publish_to：
EUROPEAN JOURNAL OF HISTOCHEMISTRY
PMID：
35638591
Hsa_circ_0030042 Ameliorates Oxidized Low-Density Lipoprotein-Induced Endothelial Cell Injury via the MiR-616-3p/RFX7 Axis
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Author：
Lei Yu, Wenbin Ma, Binghui Song, Shuqing Wang, Xinying Li, Zhao Wang
IF：
1.8230
Publish_to：
International Heart Journal
PMID：
35831154
RNA Binding Protein IGF2BP3 Rehabilitates Glycolysis of Vascular Endothelial Cells to Protect the ox-LDL-induced Cellular Injury via Stabilizing LDHA mRNA
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Author：
Mo Xing-Chun, Lu Ping, Wei Qu-Cheng, Yang Xiao-Jing
IF：
1.8000
Publish_to：
CELL BIOCHEMISTRY AND BIOPHYSICS
PMID：
40159306
miR-19a-3p affected ox-LDL-induced SDC-1/TGF-β1/Smad3 pathway in atherosclerosis
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Author：
Qiao Jin, Yiming Deng, Liang Li, Ran Chen, Luping Jiang
IF：
1.6000
Publish_to：
CELLULAR AND MOLECULAR BIOLOGY
PMID：
37300685
Triptolide Alleviates Oxidized LDL-Induced Endothelial Inflammation by Attenuating the Oxidative Stress-Mediated Nuclear Factor-Kappa B Pathway
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Author：
Shiyu Zhang, Shiyang Xie, Yuan Gao, Youping Wang
IF：
1.5000
Publish_to：
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
PMID：
35989981
circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells
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Author：
Shanwu Wu, Sheng Yang, Hongyan Qu
IF：
0.9380
Publish_to：
Open Life Sciences
PMID：
34676300
技术问答
（2）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
这个一般在铺96孔板的时候是需要多少浓度的呀，做细胞实验是可以用纯水稀释吗?2023-09-11 17:23:14
您好，具体的使用浓度，您可根据实验要求查一下相关的文献，建议是用PBS缓冲液稀释。
请问OX-LDL的有效期是从开封后开始算六周吗？如果收到货后立马分装冻存在低温度下也是六周保质期吗?2023-03-21 17:48:01
您好，该产品是从生产日期起在2-8℃可稳定保存6周，该产品严禁冻存。