| 基因名 |
IFIH1 |
| 别名 |
CADM-140 autoantigen;Clinically amyopathic dermatomyositis autoantigen 140 kDa;DEAD/H (Asp Glu Ala Asp/His) box polypeptide;DEAD/H box polypeptide;Helicard;Helicase with 2 CARD domains;Hlcd;IDDM 19;IDDM19;IFIH 1;Ifih1;IFIH1_HUMAN;Interferon induced helicase C domain containing protein 1;interferon induced with helicase C domain 1;Interferon induced with helicase C domain protein 1;Interferon-induced helicase C domain-containing protein 1;Interferon-induced with helicase C domain protein 1;MDA 5;MDA-5;Melanoma differentiation associated protein 5;Melanoma differentiation-associated gene 5;Melanoma differentiation-associated protein 5;MGC133047;Murabutide down regulated protein;Murabutide down-regulated protein;RH 116;RH116;RIG I like receptor 2;RLR 2;RNA helicase DEAD box protein 116;RNA helicase-DEAD box protein 116 |
| 英文名称 |
Recombinant human IFIH1 protein |
| 全名 |
interferon induced with helicase C domain 1 |
| 中文名称 |
含干扰素诱导解旋酶C域蛋白1 |
| 外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
| 纯度 |
≥85% by SDS-PAGE. |
| 储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
| 运输条件 |
冷藏运输 |
| 浓度 |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
Q9BYX4 |
| Gene ID |
64135 |
| 交叉反应 |
Human Mouse |
| 分子量 |
25kDa |
| 区间范围 |
1-217aa |
| 背景说明 |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. |
| 应用 |
Immunology research |
| 来源 |
E.coli |
| 纯化方法 |
NI-NTA affinity purification |
| 溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 内毒素 |
Not measured |
| 生物活性 |
NO |
| 标签信息 |
With a 6×His tag at the N/C-terminus. |
| 规格 |
10ug 50ug 100ug 1mg |
| 研究领域 |
炎症与自身免疫疾病 |
| 单位 |
支 |
| 属性分类 |
重组抗原 |
| Y-研究领域 |
炎症与自身免疫疾病 |
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