基因名 |
PADI2 |
别名 |
KIAA0994;OTTHUMP00000044625;PAD 2;PAD H19;PAD-H19;PAD2;PADI 2;Padi2;PADI2 protein;PADI2_HUMAN;PDI 2;PDI2;Peptidlyarginine deiminase type II;Peptidyl arginine deiminase II;Peptidyl arginine deiminase type II;Peptidylarginine deiminase II;Protein arginine deiminase;Protein arginine deiminase type 2;Protein arginine deiminase type II;Protein-arginine deiminase type II;Protein-arginine deiminase type-2 |
英文名称 |
Recombinant human PADI2 protein |
全名 |
peptidyl arginine deiminase,type II |
中文名称 |
肽基精氨酸脱亚胺酶2 |
外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
运输条件 |
冷藏运输 |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q9Y2J8 |
Gene ID |
11240 |
交叉反应 |
Human Mouse (Pig) |
分子量 |
40kDa |
区间范围 |
1-350aa |
背景说明 |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
研究领域 |
神经科学研究 |
单位 |
支 |
属性分类 |
重组抗原 |
Y-研究领域 |
神经科学研究 |