基因名 |
ABCA8 |
别名 |
ABCA 8;ATP binding cassette sub family A member 8;ATP binding cassette,sub family A (ABC1),member 8;ABC-type organic anion transporter ABCA8;ATP-binding cassette sub-family A member 8;KIAA0822 |
英文名称 |
Recombinant human ABCA8 protein |
全名 |
ATP-binding cassette,sub-family A (ABC1),member 8 |
中文名称 |
ATP结合盒转运体亚家族A成员8 |
外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
运输条件 |
冷藏运输 |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
O94911 |
Gene ID |
10351 |
交叉反应 |
Human Mouse |
分子量 |
18kDa |
区间范围 |
60-214aa |
背景说明 |
Isoform 1:Catalyzes the import of organic anions such as taurocholate and estrone sulfate in an ATP-dependent manner (PubMed:12379217).In vitro, also imports ochratoxin A (PubMed:12379217).In addition mediates the cholesterol efflux in an apolipoprotein independent manner an plays a role in sphingomyelin production in oligodendrocytes (PubMed:23560799).Isoform 3:Catalyzes the cholesterol and taurocholate efflux in an ATP-dependent manner (PubMed:29300488).Through the interaction with ABCA1 potentiates the cholesterol efflux to lipid-free APOA1, in turn regulates high-density lipoprotein cholesterol levels (PubMed:28882873). |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
研究领域 |
代谢性疾病研究 |
单位 |
支 |
属性分类 |
重组抗原 |
Y-研究领域 |
代谢性疾病研究 |