基因名 |
IL33 |
别名 |
C9orf26;DVS27;IL1F11;NF-HEV;NFEHEV |
英文名称 |
Recombinant human IL33 protein |
全名 |
interleukin 33 |
中文名称 |
白细胞介素33 |
外观(性状) |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
运输条件 |
The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
O95760 |
Gene ID |
90865 |
交叉反应 |
Human Mouse Rat (Dog Orangutan) |
分子量 |
31kDa |
区间范围 |
1-270aa |
背景说明 |
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation. |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
研究领域 |
炎症与自身免疫疾病 |
单位 |
支 |
属性分类 |
重组抗原 |
Y-研究领域 |
炎症与自身免疫疾病 |