基因名 |
PSMC4 |
别名 |
MB67 interacting protein,MIP224,PSMC4,S6,Tat binding protein 7,TBP 7,TBP7 |
英文名称 |
Recombinant human PSMC4 protein |
全名 |
proteasome (prosome,macropain) 26S subunit,ATPase,4 |
中文名称 |
蛋白酶体26S亚基6B |
外观(性状) |
Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.5M NaCl, 10% Gly, pH8.0. |
纯度 |
≥85% by SDS-PAGE. |
储存条件 |
Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles. |
运输条件 |
干冰运输 |
浓度 |
1mg/ml by SDS-PAGE. |
Swiss Prot |
P43686-2 |
Gene ID |
5704 |
交叉反应 |
Human Mouse Rat (Bovine Monkey) |
分子量 |
43kDa |
区间范围 |
1-387aa |
背景说明 |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly.The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene |
应用 |
Immunology research |
来源 |
E.coli |
纯化方法 |
NI-NTA affinity purification |
溶剂 |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
内毒素 |
Not measured |
生物活性 |
NO |
标签信息 |
With a 6×His tag at the N/C-terminus. |
规格 |
10ug 50ug 100ug 1mg |
单位 |
支 |
属性分类 |
重组抗原 |