Hepatic FXR-FGF4 is required for bile acid homeostasis via an FGFR4-LRH-1 signal node under cholestatic stress
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Author：
Lintao Song, Yushu Hou, Da Xu, Xijia Dai, Jianya Luo, Yi Liu, Zhuobing Huang, Miaomiao Yang, Jie Chen, Yue Hu, Chuchu Chen, Yuli Tang, Zhiheng Rao, Jianjia Ma, Minghua Zheng, Keqing Shi, Chao Cai, Mingqin Lu, Ruqi Tang, Xiong Ma, Cen Xie, Yongde Luo, Xiao
Publish_to：
Cell Metabolism
10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically
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Author：
Geng Nana, Fan Mengtian, Kuang Biao, Zhang Fengmei, Xian Menglin, Deng Lin, Chen Cheng, Pan Yiming, Chen Jianqiang, Feng Naibo, Liang Li, Ye Yuanlan, Liu Kaiwen, Li Xiaoli, Du Yu, Guo Fengjin
Publish_to：
Nature Communications
Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway
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Author：
Zejun Yue, Yirong Zhang, Wei Zhang, Nanbo Zheng, Jiazeng Wen, Lingxuan Ren, XiaoYu Rong, Liang Bai, Rong Wang, Sihai Zhao, Enqi Liu, Weirong Wang
Publish_to：
Journal of Advanced Research
Dihydroartemisinin beneficially regulates splenic immune cell heterogeneity through the SOD3-JNK-AP-1 axis
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Author：
Zhang Yiwei, Li Qilong, Jiang Ning, Su Ziwei, Yuan Quan, Lv Lei, Sang Xiaoyu, Chen Ran, Feng Ying, Chen Qijun
Publish_to：
Science China-Life Sciences
Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models
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Author：
Jiali Dong, Yuan Li, Huiwen Xiao, Shuqin Zhang, Bin Wang, Haichao Wang, Yiliang Li, Saijun Fan, Ming Cui
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance; neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis
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Author：
Cheng X; Chi L; Lin T; Liang F; Pei Z; Sun J; Teng
Publish_to：
J Neuroinflammation
Flavonoid-rich extract of Paederia scandens (Lour.) Merrill improves hyperuricemia by regulating uric acid metabolism and gut microbiota
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Author：
Yuyi Liu, Shanling Sheng, Linye Wu, Huixian Wang, Hui Xue, Ruimin Wang
Publish_to：
FOOD CHEMISTRY
Triton modified polyethyleneimine conjugates assembled with growth arrest-specific protein 6 for androgenetic alopecia transdermal gene therapy
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Author：
Xinli Fan, Xiaoran Zhao, Jianfei Xu, Jing Wang, Qian Wang, Xinjing Tang
Publish_to：
Materials Today Bio
Characterization and antibacterial activity of edible films based on carboxymethyl cellulose, Dioscorea opposita mucilage, glycerol and ZnO nanoparticles
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Author：
Xiaojing Li, Zeyue Ren, Ruijiao Wang, Lu Liu, Jie Zhang, Fanyi Ma, Md. Zaved Hossain Khan, Dongbao Zhao, Xiuhua Liu
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FOOD CHEMISTRY
Iguratimod ameliorates bleomycin-induced pulmonary fibrosis by inhibiting the EMT process and NLRP3 inflammasome activation
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Author：
Liu W; Han X; Li Q; Sun L; Wang J
Publish_to：
Biomedicine & Pharmacotherapy
Silibinin Alleviates Muscle Atrophy Caused by Oxidative Stress Induced by Cisplatin through ERK/FoxO and JNK/FoxO Pathways
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Author：
Meng-yi Chi, Hong Zhang, Ya-xian Wang, Xi-peng Sun, Quan-jun Yang, Cheng Guo
Publish_to：
Oxidative Medicine and Cellular Longevity
Chlorogenic acid reduces inflammation by inhibiting the elevated expression of KAT2A to ameliorate lipopolysaccharide-induced acute lung injury
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Author：
Bin Lv, Jinhe Guo, Yaodong Du, Yang Chen, Xin Zhao, Bin Yu, Jiarui Liu, Tianyi Cui, Haoping Mao, Xiaoying Wang, Xiumei Gao
Publish_to：
BRITISH JOURNAL OF PHARMACOLOGY
Neisseria sicca and Corynebacterium matruchotii inhibited oral squamous cell carcinomas by regulating genome stability
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Author：
Xin Shen, Bo Zhang, Xiaoyu Hu, Jia Li, Miaomiao Wu, Caixia Yan, Yutao Yang, Yan Li
Publish_to：
Bioengineered
Tetrandrine alleviates macrophage activation syndrome after CAR-T cell therapy
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Author：
Youming Wang, Li Ding, Yingxiang Wang, Hui Li, Miaomiao Wu, Sujun Li, Qianwen Xu, Yuanli Chen, Xingbing Wang
Publish_to：
PHYTOMEDICINE
Protective effects of Ligularia fischeri root extracts against ulcerative colitis in mice through activation of Bcl-2/Bax signalings
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Author：
Yong-Ping Fu, Huan Yuan, Yan Xu, Ru-Ming Liu, Yi Luo, Jian-Hui Xiao
Publish_to：
PHYTOMEDICINE
Improving the physicochemical and in vitro hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49
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Author：
Chaoran Yang, Ying Ma, Yi Chen, Jianhua Xie, Xiaobo Hu, Qiang Yu
Publish_to：
Food & Function
Puerarin Prevents Cadmium-Induced Neuronal Injury by Alleviating Autophagic Dysfunction in Rat Cerebral Cortical Neurons
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Author：
Wang L; Wang T; Wen S; Song R; Zou H; Gu J; Liu X; Bian J; Liu Z; Yuan Y.
Publish_to：
International Journal of Molecular Sciences
Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats
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Author：
Xiaofei Zhou, Bowei Zhang, Xiuli Zhao, Pixian Zhang, Jingting Guo, Yuan Zhuang, Shuo Wang
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Characterization and application of a novel xylanase from Halolactibacillus miurensis in wholewheat bread making.
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Author：
Yaping Zhang, Chun Liu, Manli Yang, Zuyun Ou, Ying Lin, Fengguang Zhao, Shuangyan Han
Publish_to：
Frontiers in Bioengineering and Biotechnology
Dihydroartemisinin imposes positive and negative regulation on Treg and plasma cells via direct interaction and activation of c-Fos
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Author：
Li Qilong, Jiang Ning, Zhang Yiwei, Liu Yize, Su Ziwei, Yuan Quan, Sang Xiaoyu, Chen Ran, Feng Ying, Chen Qijun
Publish_to：
Communications Biology
Chlorogenic Acid Prevents Hyperuricemia Nephropathy via Regulating TMAO-Related Gut Microbes and Inhibiting the PI3K/AKT/mTOR Pathway
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Author：
Xiaofei Zhou, Bowei Zhang, Xiuli Zhao, Yongxi Lin, Yuan Zhuang, Jingting Guo, Shuo Wang
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Sinapic Acid Reduces Oxidative Stress and Pyroptosis via Inhibition of BRD4 in Alcoholic Liver Disease
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Author：
Chu Junyi, Yan Ran, Wang Sai, Li Guoyang, Kang Xiaohui, Hu Yan, Lin Musen, Shan Wen, Zhao Yan, Wang Zhecheng, Sun Ruimin, Yao Jihong, Zhang Ning
Publish_to：
Frontiers in Pharmacology
Gene expression analysis to identify mechanisms underlying improvement of myocardial fibrosis by finerenone in SHR
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Author：
Ming-shuang Zhou, Shao-ying Zheng, Cheng Chen, Xue Li, Qin Zhang, Ya-jing Zhao, Wen Zhang
Publish_to：
BIOCHEMICAL PHARMACOLOGY
SPP1 promotes the polarization of M2 macrophages through the Jak2/Stat3 signaling pathway and accelerates the progression of idiopathic pulmonary fibrosis
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Author：
Xuelian Yang, Ziqin Liu, Jiawei Zhou, Jianqiang Guo, Tao Han, Yafeng Liu, Yunyun Li, Ying Bai, Yingru Xing, Jing Wu, Dong Hu
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Metronomic capecitabine with rapamycin exerts an immunosuppressive effect by inducing ferroptosis of CD4+ T cells after liver transplantation in rat
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Author：
Hao Wang, Ruining Yang, Zhenglu Wang, Lei Cao, Dejun Kong, Qian Sun, Sei Yoshida, Jiashu Ren, Tao Chen, Jinliang Duan, Jianing Lu, Zhongyang Shen, Hong Zheng
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
Asiatic acid alleviates LPS-induced acute kidney injury in broilers by inhibiting oxidative stress and ferroptosis via activation of the Nrf2 pathway
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Author：
Wenyue Qiu, Xinting Zhang, Xiaoyue Pang, Jianjia Huang, Shuilian Zhou, Rongmei Wang, Zhaoxin Tang, Rongsheng Su
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
Integration of metabolomics and network pharmacology to reveal the protective mechanism underlying Wogonoside in acute myocardial ischemia rats
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Author：
Wenzhong Feng, Cancan Duan, Fuzhu Pan, Caiying Yan, Hongjing Dong, Xiao Wang, Jianyong Zhang
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis
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Author：
Xiaofei Zhou, Bowei Zhang, Xiuli Zhao, Yongxi Lin, Jin Wang, Xiaowen Wang, Nan Hu, Shuo Wang
Publish_to：
Food & Function
N-Acetyl-l-tryptophan inhibits CCl4-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal
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Author：
Tingting Ma, Huanli Cheng, Tongxi Li, Yifan Chen, Tianying Cai, Junjie Bai, Ziming Wu, Xianming Xia, Tiancheng Liang, Yichao Du, Wenguang Fu
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BIOORGANIC CHEMISTRY
Florfenicol core–shell composite nanogels as oral administration for efficient treatment of bacterial enteritis
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Author：
Wanhe Luo, Jinhuan Liu, Mengdi Zhang, Yongtao Jiang, Beibei Sun, Shuyu Xie, Ali Sobhy Dawood, Samah Attia Algharib, Xiuge Gao
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
Glycoside hydrolase family 5 gene Pp07886 in Pythium porphyrae: Identification,characterization,expression pattern,and activation of the host immunity
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Author：
Huichao Yang, Peiwen Weng, Zaiduo Liu, Yongwei Yan, Lei Tang, Jie Li, Yunxiang Mao, Zhaolan Mo
Publish_to：
Algal Research-Biomass Biofuels and Bioproducts
The Effect of Decreased Ca++/Mg++ ATPase Activity on Lactobacillus delbrueckii subsp. bulgaricus sp1.1 Survival during Spray Drying
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Author：
Jialei Sun, Wenjing Cai, Yu Wang, Haiyue Niu, Xi Chen, Xue Han
Target RNA expression omics approach to reveal the liver detoxification effect induced by Chinese medicine prescription Niu Huang Jie Du against realgar overexposure to mice
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Author：
Juan Wu, Dongqing Yang, Ziwei Song, Qin Qian, Jianguo Dai, Ju Dong
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JOURNAL OF ETHNOPHARMACOLOGY
Apigenin alleviates oxidative stress-induced myocardial injury by regulating SIRT1 signaling pathway
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Author：
Kun Xu, Yao Yang, Ming Lan, Jiannan Wang, Bing Liu, Mingjing Yan, Hua Wang, Wenlin Li, Shenghui Sun, Kaiyi Zhu, Xiyue Zhang, Mingyan Hei, Xiuqing Huang, Lin Dou, Weiqing Tang, Qing He, Jian Li, Tao Shen
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
Hepatoprotective action mechanism and quantification of soyasaponin Bb in Abri Herba by HPLC and network pharmacology
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Author：
Xingmei Lin, Chengzhong Zhang, Baokang Huang
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
Curcumin Inhibits T Follicular Helper Cell Differentiation in Mice with Dextran Sulfate Sodium (DSS)-Induced Colitis
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Author：
Hai-Yan Wang, Wei Ge, Su-Qing Liu, Jian Long, Qing-Qing Jiang, Wen Zhou, Zheng-Yun Zuo, Duan-Yong Liu, Hai-Mei Zhao, You-Bao Zhong
Publish_to：
AMERICAN JOURNAL OF CHINESE MEDICINE
Umbelliferone ameliorates renal function in diabetic nephropathy rats through regulating inflammation and TLR/NF-κB pathway
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Author：
Wang HQ; Wang SS; Chiufai K; Wang Q; Cheng XL
Publish_to：
Chin J Nat Med
Demyelination and remyelination detected in an alternative cuprizone mouse model of multiple sclerosis with 7.0 T multiparameter magnetic resonance imaging
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Author：
Ding Shuang, Guo Yu, Chen Xiaoya, Du Silin, Han Yongliang, Yan Zichun, Zhu Qiyuan, Li Yongmei
Publish_to：
Scientific Reports
Myricetin and M10, a myricetin-3-O-β-d-lactose sodium salt, modify composition of gut microbiota in mice with ulcerative colitis
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Author：
Rong-Rong Miao, Sheng Zhan, Xue-Tao Hu, Wen-Min Yuan, Li-Juan Wu, Shu-Xiang Cui, Xian-Jun Qu
Publish_to：
TOXICOLOGY LETTERS
Orderly Regulation of Macrophages and Fibroblasts by Axl in Bleomycin-Induced Pulmonary Fibrosis in Mice
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Author：
Xinyu Zhao, Yupeng Li, Shengnan Yang, Yicong Chen, Kaiwei Wu, Jing Geng, Peipei Liu, Zai Wang, Huaping Dai, Chen Wang
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Borneol promotes berberine-induced cardioprotection in a rat model of myocardial ischemia/reperfusion injury via inhibiting P-glycoprotein expression
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Author：
Xinxin Pan, Jing Tao, Qijing Xing, Baoli Wang, Mengyun Dou, Ye Zhang, Shiyun Jin, Juan Wu
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EUROPEAN JOURNAL OF PHARMACOLOGY
Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Tongmai Yangxin Pills in Ameliorating Doxorubicin-Induced Cardiotoxicity
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Author：
Lexin Shu, Yuming Wang, Wei Huang, Simiao Fan, Junhua Pan, Qingbo Lv, Lin Wang, Yujing Wang, Jinpeng Xu, Haifeng Yan, Yuchao Bai, Yi Wang, Yubo Li
The Promoting Effect of a Local Pulsatile Parathyroid Hormone Delivery on Healing of the Mandibular Fracture in Rats
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Author：
Yuanyuan Jia, Mianmian Duan, Yan Yang, Dongxiang Wang, Qiang Dong, Jian Liao, Ling Mao, Poyu Liu, Ling Feng, Jin Chen, Zhenglong Tang
Publish_to：
Tissue Engineering Part A
Discovery and characterization of a novel PKD-Fn3 domains containing GH44 endoglucanase from a Tibetan metagenomic library
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Author：
Lyu Yunbin, Luo Hao, Chai Shumao, Zhang Ying, Fan Xinyu, Wang Shaochen, Feng Zhiyang
Publish_to：
JOURNAL OF APPLIED MICROBIOLOGY
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF- B molecular pathway
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Author：
Antonia Otoo, Armin Czika, Jones Lamptey, Jun-Pu Yang, Qian Feng, Mei-Jiao Wang, Ying-Xiong Wang, Yu-Bin Ding
Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition
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Author：
Ziyu Wu， Dan Li， Dingyuan Tian， Xuejun Liu， Zhongming Wu
Berberine up-regulates miR-340-5p to protect myocardial ischaemia/reperfusion from HMGB1-mediated inflammatory injury
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Author：
Tianyi Long, Wei Pan, Fei Li, Sayed Ali Sheikh, Qiying Xie, Chenglong Zhang
Publish_to：
ESC Heart Failure
Exposure to ethylparaben and propylparaben interfere with embryo implantation by compromising endometrial decidualization in early pregnant mice
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Author：
Dan Wang, Weike Li, Chengshun Yang, Xuemei Chen, Xueqing Liu, Junlin He, Chao Tong, Chuan Peng, Yubin Ding, Yanqing Geng, Xianqing Cao, Fangfang Li, Rufei Gao, Yingxiong Wang
Publish_to：
JOURNAL OF APPLIED TOXICOLOGY
Hyperoside Protects Trastuzumab-Induced Cardiotoxicity via Activating the PI3K/Akt Signaling Pathway
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Author：
Wei Shanshan, Ma Wanjun, Xie Suifen, Liu Sa, Xie Ning, Li Wenqun, Zhang Bikui, Liu Jian
Publish_to：
CARDIOVASCULAR DRUGS AND THERAPY
Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis
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Author：
Shao-Jie Gao, Dan-Yang Li, Dai-Qiang Liu, Jia Sun, Long-Qing Zhang, Jia-Yi Wu, Fan-He Song, Ya-Qun Zhou, Wei Mei
Publish_to：
Molecular Pain
Emodin Alleviates Intestinal Barrier Dysfunction by Inhibiting Apoptosis and Regulating the Immune Response in Severe Acute Pancreatitis
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Author：
Qi Zhou, Hong Xiang, Han Liu, Bing Qi, Xueying Shi, Wenhui Guo, Jiacheng Zou, Xueting Wan, Wenjing Wu, Zhengpeng Wang, Wenhui Liu, Shilin Xia, Dong Shang
Rapid identification of chemical components in vitro and in vivo of Menispermi Rhizoma by integrating UPLC-Q-TOF-MS with data post-processing strategy
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Author：
Jinxia Wei, Yuanyuan Wang, Yue Zhang, Yanxue Zheng, Jia Shao, Wenbo Cheng, Yubo Li
Publish_to：
PHYTOCHEMICAL ANALYSIS
Tuberostemonine may alleviates proliferation of lung fibroblasts caused by pulmonary fibrosis
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Author：
Amei Tang, Yang Liu, Qian Ding, Gao Huang, Zongge Sha, Changfu Yang, Feng Cao
Publish_to：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
Lipidomics reveals serum lipid metabolism disorders in CTD-induced liver injury
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Author：
Li Shan, Duan Xiaotong, Zhang Yixin, Zhao Cancan, Yu Ming, Li Xiaofei, Li Xiaomei, Zhang Jianyong
Publish_to：
BMC Pharmacology & Toxicology
Berberine alleviates AGEs-induced ferroptosis by activating NRF2 in the skin of diabetic mice
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Author：
Chunjie Jiang, Guojuan Lao, Jianmin Ran, Ping Zhu
Publish_to：
EXPERIMENTAL BIOLOGY AND MEDICINE
Optimization and Evaluation of the Quercus infectoria Galls Thermosensitive In Situ Gel for Rectal Delivery
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Author：
Abdulaziz Arkin, Aliya Elham, Arfidin Anwar, Gulina Kalimanjiang, Mubarak Iminjan
Publish_to：
Evidence-based Complementary and Alternative Medicine
Yishen capsule promotes podocyte autophagy through regulating SIRT1/NF-κB signaling pathway to improve diabetic nephropathy
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Author：
Yuxiang Liu, Wenyuan Liu, Ziyuan Zhang, Yaling Hu, Xiaodong Zhang, Yanyan Sun, Qingqing Lei, Dalin Sun, Ting Liu, Yanjun Fan, Hui Li, Wujie Ding, Jingai Fang
Publish_to：
RENAL FAILURE
Preventive effect of imperatorin against doxorubicin-induced cardiotoxicity through suppression of NLRP3 inflammasome activation
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Author：
Zhang Hao, Ding Xiaoyun, Qiu Yumei, Xie Mengdie, Wang Hu, Li Tingting, Bao Huiyun, Huang Si, Xiong Yinhua, Tang Xilan
Publish_to：
Journal of Natural Medicines
Integrating Network Pharmacology and Experimental Validation to Reveal the Mechanism of Vine Grape Tea Polyphenols on Hyperuricemia-Induced Renal Injury in Mice
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Author：
Xiaoli Li, Baoying Li, Xinyue Meng, Fei Yu, Xin Yu, Wenqian Zhao, Yajuan Wang, Haiqing Gao, Mei Cheng, Lihong Zhong
Publish_to：
JOURNAL OF MEDICINAL FOOD
Asiatic Acid Alleviates LPS-Induced Pyroptosis and Endoplasmic Reticulum Stress-Mediated Apoptosis via Inhibiting the HMGB1/TLR4/NF-κB Pathway in Broiler Hepatocytes
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Author：
Wenyue Qiu, Wenxin Jiang, Yiman Su, Hui Huang, Jiali Ye, Rongmei Wang, Zhaoxin Tang, Rongsheng Su
Publish_to：
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
Dioscin ameliorates inflammatory bowel disease by up-regulating miR-125a-5p to regulate macrophage polarization.
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Author：
Shi L; Zhang P; Jin R; Chen X; Dong L; Chen W.
Publish_to：
J Clin Lab Anal.
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这一款可以用来溶解药物给小鼠灌胃嘛?2023-09-04 11:22:27
您好，试剂为小分子化合物，不仅可应用于常规的生化实验，还满足于体外/体内相关实验的纯度要求，可用于细胞、动物等病理研究。