中文
英语
产品简介
| 中文名称 | 改良油红O染色试剂盒 |
| 英文名称 | Modified Oil Red O Stain Kit |
| 储存条件 | 2-8℃，避光保存，有效期6个月。 |
| 规格 | 2*50ml 2*100ml |
| 单位 | 盒 |
脂质(Lipid)是中性脂肪、类脂及其衍生物的总称，不溶于水，易溶于有机溶剂(例如乙醇、乙醚等)。 中性脂肪染色常采用苏丹染料，最近发现偶氮染料油红 O 更适合脂肪的染色。油红 O 是很强的脂溶剂和 染脂剂，较易与甘油三脂结合呈小脂滴状，与磷脂结合力稍差。其染色原理是染料在脂质的溶解度较在原 溶剂中的溶解度更大，所以在染色时染料就从有机溶剂转移入脂质而使脂肪染色。
改良油红O染色试剂盒主要用于显示组织器官的脂肪变性和类脂质的异常沉着，常发生于肝、肾、心等实质脏器的脂肪变性，细胞内出现多数中性脂肪滴；鉴别和诊断脂肪组织中所发生的肿瘤及其性质。标本不采用含有乙醇的固定液(如需要固定可采用10%的福尔马林)、也不采用石蜡切片，需用冰冻切片或碳蜡切片。脂肪的阳性染色结果呈橘黄至红色，具体颜色因脂质浓度而定。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
脂肪肝造模冰冻切片
脂肪液滴着红色，细胞核着蓝色
脂肪液滴着红色，细胞核着蓝色
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PMID：
35079982
Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells
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Author：
Fang Zheng, Jingjing Su, Jiaoman Wang, Qing Zhan, Mei Su, Sicheng Ding, Wei Li, Ying-Ting Zhu, Ping Guo
IF：
5.0000
Publish_to：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
PMID：
38502139
Suppression of FOXC1 induces pyroptosis of the coronary artery through activation of JAK2
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Author：
Jiayun Qiu, Yahong Fu, Ting Tian, Yan Mao, Qiang Tian, Lanbo Zhou, Rui Jin, Lili Zhuang, Guoping Zhou
IF：
4.9000
Publish_to：
ATHEROSCLEROSIS
PMID：
39182474
Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice
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Author：
Tong Dan, Xiang Jie, Liu Wei, Sun Fang, Wang Lijuan, Mou Aidi, Cao Tingbing, Zhou Qing, You Mei, Liao Yingying, Gao Peng, Liu Daoyan, Lu Zongshi, Zhu Zhiming
IF：
4.8000
Publish_to：
Diabetology & Metabolic Syndrome
PMID：
38302999
Identification of polyunsaturated fatty acids related key modules and genes in metabolic dysfunction-associated fatty liver disease using WGCNA analysis
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Author：
Xiao Cheng, Chen Siliang, Yang Chunru, Liu Jieying, Yu Miao
IF：
4.7720
Publish_to：
Frontiers in Genetics
PMID：
36425072
Integrated pyroptosis measurement and metabolomics to elucidate the effect and mechanism of tangzhiqing on atherosclerosis
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Author：
Chen Rui, Chen Ting, Zhou Zhihuan, Song Zhihui, Feng Wanying, Yang Xintong, Wang Xianliang, Li Bin, Ding Xinya, Zhang Han, Wang Yi
IF：
4.7550
Publish_to：
Frontiers in Physiology
PMID：
36171973
Helicobacter mastomyrinus infection induces autoimmune hepatitis in mice
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Author：
Liqi Zhu, Yuanyuan Liang, Linghan Yang, Qihui Yang, Jun Yin, Tao Wang, Xiangming Xu, Quan Zhang
IF：
4.7000
Publish_to：
Journal of Translational Autoimmunity
PMID：
39981114
Senolytic elimination of senescent cells improved periodontal ligament stem cell-based bone regeneration partially through inhibiting YAP
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Author：
Linglu Jia, Han Xiao, Zhenghao Hao, Shaoqing Sun, Wenxi Zhao, Zikai Gong, Weiting Gu, Yong Wen
IF：
4.6000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
PMID：
39971252
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation
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Author：
Xingguo Miao, Hui Ye, Xiaoya Cui, Xiuxiu Guo, Feifei Su
IF：
4.5000
Publish_to：
NUTRITION RESEARCH
PMID：
37826994
Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice
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Author：
Yihong Yang, Guanghua Xiong, Huangqi Shi, Yulin Peng, Jinghong Liu, Yaxuan Jiang, Min Lu, Hongbo Liu, Yong Liu
IF：
4.4000
Publish_to：
Frontiers in Pharmacology
PMID：
40012630
FTO Stabilizes MIS12 to Inhibit Vascular Smooth Muscle Cell Senescence in Atherosclerotic Plaque
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Author：
Jingzhao Sun, Mengqi Wang, Fengming Jia, Jiantao Song, Jinlin Ren, Bo Hu
IF：
4.2000
Publish_to：
Journal of Inflammation Research
PMID：
38523689
Loss of RAGE prevents chronic intermittent hypoxia-induced nonalcoholic fatty liver disease via blockade of NF-кB pathway
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Author：
Tan Haoqu, Hu Jinfang, Zuo Wei, Huang Yun, Cui Jian, Gong Fei, Bai Wei
IF：
4.1840
Publish_to：
GENE THERAPY
PMID：
35821256
Roles of human periodontal ligament stem cells in osteogenesis and inflammation in periodontitis models: Effect of 1α,25-dihydroxyvitamin D3
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Author：
Jing-jiao Wang, Cheng-lei Zhang, Xiao-qian Guo, Chang-yi Yang
IF：
4.1000
Publish_to：
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
PMID：
37331433
Machine learning prediction of obesity-associated gut microbiota: identifying Bifidobacterium pseudocatenulatum as a potential therapeutic target
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Author：
Hao Wu, Yuan Li, Yuxuan Jiang, Xinran Li, Shenglan Wang, Changle Zhao, Ximiao Yang, Baocheng Chang, Juhong Yang, Jianjun Qiao
IF：
4.0000
Publish_to：
Frontiers in Microbiology
PMID：
39974372
A multi-target protective effect of Danggui-Shaoyao-San on the vascular endothelium of atherosclerotic mice
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Author：
Sun Yuemeng, Gao Yushan, Zhou Lu, Lu Yixing, Zong Yulin, Zhu Haoyu, Tang Yang, Zheng Fengjie, Sun Yan, Li Yuhang
IF：
3.9000
Publish_to：
BMC Complementary Medicine and Therapies
PMID：
36803348
Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11
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Author：
Jianjie Rong, Chuanyong Li, Qiang Zhang, Guangfeng Zheng, Weijian Fan, Zhichang Pan, Shuming Shi
IF：
3.8000
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
37410531
HDAC1 overexpression promoted by METTL3-IGF2BP2 inhibits FGF21 expression in metabolic syndrome-related liver injury
点击查看 >>
Author：
Yunjiang Chen, Kaiyu Cai, Yueling Du, Zixiong Liu, Yanchun Gong
IF：
3.7300
Publish_to：
Biochemistry and Cell Biology
PMID：
36542845
Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor
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Author：
Yu Qi, Chen Ying, Zhao Youlu, Huang Shuo, Xin Xiaohong, Jiang Lei, Wang Hui, Wu Wenyan, Qu Lei, Xiang Chengang, Wang Suxia, Liu Gang, Yang Li
IF：
3.7000
Publish_to：
Kidney Diseases
PMID：
37927402
Insufficient sleep disrupts glucose metabolism during pregnancy by inhibiting PGC-1α.
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Author：
Hao Wu, Cong Lu, Xing Li, Xianming Xu, Sufang Wu
IF：
3.6160
Publish_to：
Annals of Translational Medicine
PMID：
36544637
Klotho senses mechanical stimuli and modulates tension-induced osteogenesis
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Author：
Xinrui Men, Wei-Cho Chiou, Xingjian Li, Qiming Li, Xinyi Chen, Kaiwen Zhang, Xiaoge Jiang, Song Chen
IF：
3.5000
Publish_to：
BONE
PMID：
40118264
The Coptidis Rhizoma and Bovis Calculus herb pair attenuates NASH and inhibits the NLRP3 inflammasome activation
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Author：
Tian Xu, Jiahui Chen, Qi Shao, Jing Ji, Qingguo Wang, Chongyang Ma, Xueqian Wang, Fafeng Cheng
IF：
3.4000
Publish_to：
Heliyon
PMID：
39149083
LINC01119 encapsulated by cancer-associated adipocytes-derived exosomes promotes M2 polarization of macrophages to induce immune escape in ovarian cancer in a 3D co-culture cell-based model
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Author：
Zheng Qingling, Zhang Jin, Liu Yanxiang, Dong Weijia, Dai Xin, Du Xiuluan, Gu Donghua
IF：
3.3400
Publish_to：
Clinical & Translational Oncology
PMID：
37142874
Gut microbiota metabolite TMAO promoted lipid deposition and fibrosis process via KRT17 in fatty liver cells in vitro
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Author：
Fulin Nian, Chen Zhu, Nuyun Jin, Qiaoyun Xia, Longyun Wu, Xiaolan Lu
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
37271025
Scutellarin Attenuates Pro-Inflammatory Foam Cell Formation and Facilitates M2 Polarization in Microglia during Copper Homeostasis Imbalance via the MAPK Signaling Pathway
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Author：
Qiting Zhao, Lingyi Chen, Yantuanjin Ma, Shufen Wang
IF：
3.3000
Publish_to：
Frontiers in Bioscience-Landmark
PMID：
40152387
Intervention of Shugan Xiaozhi Decoction on Nonalcoholic Fatty Liver Disease via Mediating Gut-Liver Axis
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Author：
Huili Yang, Lian Feng, Linyi Xu, Dansheng Jiang, Fenfen Zhai, Guangdong Tong, Yufeng Xing
IF：
3.2460
Publish_to：
Biomed Research International
PMID：
35837380
Carbon monoxide as a negative feedback mechanism on HIF-1α in the progression of metabolic-associated fatty liver disease
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Author：
Yingying Cui, Kai Yang, Chunyu Guo, Zhengmei Xia, Benchun Jiang, Yanni Xue, Bingdong Song, Weirong Hu, Mingjie Zhang, Yanyan Wei, Cheng Zhang, Shichen Zhang, Jun Fang
IF：
3.2000
Publish_to：
NITRIC OXIDE-BIOLOGY AND CHEMISTRY
PMID：
39369813
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells
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Author：
Shu Zeng, Min Tao, Lei Yuan, Lili Zhang, Xie Luo
IF：
3.1000
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
36842305
C1QBP Promotes Prostate Cancer Progression and Lipid Accumulation by Negatively Regulating ALDH9A1
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Author：
Xinyu Liu, Jiaxin Li, Runxuan Du, Qiufang Qiao, Shuang Liu, Zhihao Bo, Ruibing Chen, Yihan Dong, Xuesong Xiao, Yuejing Pan, Huamao Jiang, Rui Wang, Yong Wang, Dan Yue
IF：
3.0000
Publish_to：
MOLECULAR CARCINOGENESIS
PMID：
40099576
LC-HRMS profiling of Dendrobium huoshanense aqueous extract and its therapeutic effects on nonalcoholic fatty liver disease in mice through the TLR2-NF-κB and AMPK-SREBP1-SIRT1 signaling pathways
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Author：
Qiyan Lin, Ke Huang, Xiyu Ge, Menghua Ma, Wei Wang, Li Yang, Cunwu Chen, Bangxing Han, Dong Liu
IF：
2.8000
Publish_to：
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
PMID：
40107184
Multi-Omics Identified THDCA as a Key Contributor to Hyperlipidemia and as a Potential Therapeutic Agent
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Author：
Zhaohuan Lou, Liping Han, Yuanguo Qu, Aizhen Zhou, He Ye, Meiqiu Yan, Bin Cheng, Muyi Liu, Tao Jiang, Jianbo Huang
IF：
2.7000
Publish_to：
Reviews in Cardiovascular Medicine
PMID：
31345004
Rhinacanthin C Ameliorates Insulin Resistance and Lipid Accumulation in NAFLD Mice via the AMPK/SIRT1 and SREBP-1c/FAS/ACC Signaling Pathways
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Author：
Zhiqiang Gong, Sha Han, Chenlin Li, Tianxiu Meng, Yu Huo, Xianfu Liu, Yanhong Huang, Lifang Yang
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
36660274
Jian-Gan-Xiao-Zhi Decoction Alleviates Inflammatory Response in Nonalcoholic Fatty Liver Disease Model Rats through Modulating Gut Microbiota
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Author：
Jiabao Liao, Xuehua Xie, Jinmei Gao, Zhaiyi Zhang, Fei Qu, Huantian Cui, Yongjun Cao, Xue Han, Jie Zhao, Weibo Wen, Hongwu Wang
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
33824675
miR-125b-5p regulates FFA-induced hepatic steatosis in L02 cells by targeting estrogen-related receptor alpha
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Author：
Fen Gao, Yanhua Ma, Chun Yu, Qianchen Duan
IF：
2.6000
Publish_to：
GENE
PMID：
40113187
IL 37 inhibits invasion and metastasis in non small cell lung cancer by suppressing the IL 6/STAT3 signaling pathway
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Author：
Mingfang Jiang, Ye Wang, Hua Zhang, Youxin Ji,
IF：
2.5690
Publish_to：
Thoracic Cancer
PMID：
29575809
Licochalcone A ameliorates lipid accumulation in metabolic dysfunction-associated steatotic liver disease via upregulating PPARα/CPT1α
点击查看 >>
Author：
Wenrui Zhu, Hongfeng Xu, Rui Yan, Luqi Qiu, Guojun Wang, Yantao Zhu
IF：
2.5000
Publish_to：
HISTOLOGY AND HISTOPATHOLOGY
PMID：
40165660
Ssc-miR-130b Enhances Cell Proliferation and Represses Adipogenesis of Primary Cultured Intramuscular Preadipocytes in Pigs
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Author：
Yunqiu Yang, Yongfang Chen, Lijun Wang, Min Du, Rui Zhang, Yao Lu, Shifeng Pan
IF：
2.0000
Publish_to：
Veterinary Sciences
PMID：
40284877
Fagopyrum dibotrys extract improves nonalcoholic fatty liver disease via inhibition of lipogenesis and endoplasmic reticulum stress in high-fat diet-fed mice
点击查看 >>
Author：
Wang Da, Zhang Dan, Zhu Ziyun, Zhang Yini, Wan Ying, Chen Hang, Liu Jianjun, Ma Lanqing
IF：
1.6000
Publish_to：
BMC Research Notes
PMID：
39415220
Oral administration of Ginkgolide B alleviates hypoxia-induced neuronal damage in rat hippocampus by inhibiting oxidative stress and apoptosis
点击查看 >>
Author：
W Li, S Qinghai, L Kai, M Xue, N Lili
IF：
1.5140
Publish_to：
Iranian Journal of Basic Medical Sciences
PMID：
30834078
Identification and Validation of Biomarkers in Metabolic Dysfunction-Associated Steatohepatitis Using Machine Learning and Bioinformatics
点击查看 >>
Author：
Yu-Ying Zhang, Jin-E Li, Hai-Xia Zeng, Shuang Liu, Yun-Fei Luo, Peng Yu, Jian-Ping Liu
IF：
1.5000
Publish_to：
Molecular Genetics & Genomic Medicine
PMID：
39995143
Downregulation of lncRNA NEAT1_2 radiosensitizes hepatocellular carcinoma cells through regulation of miR 101 3p/WEE1 axis
点击查看 >>
Author：
Xin Chen Nuobei Zhang
IF：
1.4820
Publish_to：
Cell biology international,
PMID：
30488993
技术问答
（18）
注意：
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可以用于细胞染色吗2025-04-07 09:30:35
您好，可以，不过需要自行准备固定液用于细胞染色前固定
染肠上皮细胞冰冻切片，建议切片厚度多大？2025-03-07 08:49:27
您好，冰冻切片一般建议厚度为8-10um
请问可以用中性树胶封固吗?2024-12-24 10:18:02
您好，不可以使用中性树胶，因为中性树胶含有有机溶剂，脂滴溶于有机溶剂
如果做心脏的冰冻切片油红染色，1261和1262区别是什么2024-12-23 21:21:24
您好，G1261适用于常规肝、肾、心等实质器官脂肪变性，G1262适用于细胞诱导脂滴染色，可显示最小的脂滴
2*50ml 和 2*100ml 分别可以染多少冰冻切片呢2024-12-23 21:16:37
您好，油红O染色一般采取浸染方式，需要根据染色器皿调整染色液用量