英文名称 |
Anti-PRKCA Polyclonal Antibody |
中文名称 |
蛋白激酶Cα |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
预测交叉反应 |
Cow(96.0%);Rabbit(98.9%) |
稀释比例 |
WB 1:1000-3000. ELISA 1:2000-20000. |
靶标 |
PRKCA |
别名 |
AAG6; Aging associated gene 6; aPKC; KPCA_HUMAN; PKC alpha; PKC-A; PKC-alpha; PKCA; PRKACA; PRKCA; Protein Kinase C alpha; Protein kinase C alpha type; KPCG_HUMAN; MGC57564; OTTHUMP00000067291; PKC-gamma; PKCC; PKCG; PRKCG; Protein kinase C gamma; Protein kinase C gamma polypeptide; Protein kinase C gamma type; Protein kinase C, gamma; SCA 14; SCA14 |
背景说明 |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. |
Swiss Prot |
P17252 |
Gene ID |
5578 |
亚细胞定位 |
Nucleus Cytoplasm Cell membrane |
免疫原 |
Recombinant protein of human PRKCA |
Public Immunogen Range |
1-350aa |
理论分子量 |
77kDa |
实际分子量 |
76kDa |
纯化方法 |
Affinity purification |
储存液 |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
20ul 50ul 100ul |
交叉反应 |
Human Monkey Rat Mouse |
应用 |
WB ELISA |
研究领域 |
神经学 细胞生物学 发育生物学 信号传导 表观遗传 |
单位 |
支 |
属性分类 |
其他抗体 |