英文名称 |
Anti-ACTN2 Polyclonal Antibody |
中文名称 |
α2辅肌动蛋白抗体 |
宿主 |
Rabbit |
克隆类型 |
Polyclonal Antibody |
亚型 |
IgG |
预测交叉反应 |
Human(100%);Cow(99.4%);Chicken(97.7%) |
稀释比例 |
IHC 1:25-100. |
靶标 |
ACTN2 |
别名 |
Actin binding protein; Actinin alpha 2; ACTN 2; ACTN2; ACTN2_HUMAN; Alpha actinin 2; Alpha actinin skeletal muscle; Alpha actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; CMD1AA; F actin cross linking protein; F-actin cross-linking protein |
背景说明 |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
Swiss Prot |
P35609 |
Gene ID |
88 |
亚细胞定位 |
Cytoplasm |
免疫原 |
Recombinant protein of human ACTN2 |
Public Immunogen Range |
1-350aa |
理论分子量 |
104kDa |
纯化方法 |
Octanoic acid-ammonium sulfate precipitation |
储存液 |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
储存条件 |
Store at -20℃. Avoid freeze / thaw cycles. |
规格 |
20ul 50ul 100ul |
交叉反应 |
Mouse Rat |
应用 |
IHC |
研究领域 |
心血管 新陈代谢 |
单位 |
支 |
属性分类 |
其他抗体 |