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Hoechst 33342染色液（1mg/mL）
英文名称:Hoechst 33342 Stain solution(1mg/ml)
储存条件:-20℃，避光，有效期1年。
产品简介
| 中文名称 | Hoechst 33342染色液（1mg/mL） |
| 英文名称 | Hoechst 33342 Stain solution(1mg/ml) |
| 别名 | bisBenzimide H 33342;HOE 33342 |
| 储存条件 | -20℃，避光，有效期1年。 |
| 规格 | 1ml 10*1ml |
| 单位 | 盒 |
Hoechst 33342，也称bisBenzimide H 33342或HOE 33342，是一种可以穿透细胞膜的蓝色荧光染料，对细胞的毒性较低。Hoechst 33342染色常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33342也常用于普通的细胞核染色，或常规的DNA染色。Hoechst 33342的最大激发波长为346nm，最大发射波长为460nm；Hoechst 33342和双链DNA结合后，最大激发波长为350nm，最大发射波长为461nm。本Hoechst 33342染色液为即用型，可直接用于固定细胞或组织的细胞核染色，也可直接用于活细胞或组织的细胞核染色。
使用说明：
使用前用生理盐水或PBS将Hoechst 33342染色液稀释100倍，即为工作液。
1. 对于固定的细胞或组织：
a. 对于细胞或组织样品，固定后，适当洗涤去除固定剂。随后如果需要进行免疫荧光染色，则先进行免疫荧光染色，染色完毕后再按后续步骤进行Hoechst 33342染色。如果不需要进行其它染色，则直接进行后续的Hoechst 33342染色。
b. 对于贴壁细胞或组织切片，加入少量Hoechst 33342工作液，覆盖住样品即可；对于悬浮细胞，至少加入待染色样品3倍体积的工作液，混匀。室温放置3-5分钟。
c. 吸除Hoechst 33342染色液，用TBST、PBS或生理盐水洗涤2-3次，每次3-5分钟。
d. 直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时，会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
2. 对于活细胞或组织：
a. 加入适当量Hoechst 33342工作液，必须充分覆盖住待染色的样品，通常对于六孔板一个孔需加入1mL工作液，对于96孔板一个孔需加入100μL工作液。
b. 在适宜于细胞培养的温度下培养20-30分钟。弃染色液，用PBS或培养液洗涤2-3次即可进行荧光检测。
注意事项：
荧光染料都存在淬灭的问题，为减缓荧光淬灭可以使用抗荧光衰减封片剂。建议染色后尽量当天完成检测，活细胞或组织染色后应立即观察。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
点击查看 >>
Author：
Yao Feng, Jin Zhen, Zheng Zihan, Lv Xiaohan, Ren Lingxuan, Yang Jianjun, Chen Danli, Wang Bo, Yang Wei, Chen Lifang, Wang Weirong, Gu Jianli, Lin Rong
IF：
7.1090
Publish_to：
Cell Death Discovery
PMID：
35279683
Ferroptosis suppressor protein 1 regulated oligodendrocytes ferroptosis rescued by idebenone in spinal cord injury
点击查看 >>
Author：
Baoyou Fan, Derong Liu, Jia Qin, Zhongju Shi, Zicheng Hu, Xiang Gao, Yifei Ren, Pengtian Zhao, Xiaoyang Chen, Yiming Ren, Guangzhi Ning, Tao Liu, Shiqing Feng
IF：
7.1000
Publish_to：
FREE RADICAL BIOLOGY AND MEDICINE
PMID：
39626861
Multifunctional Nanoparticles-Mediated PTT/PDT Synergistic Immune Activation and Antitumor Activity Combined with Anti-PD-L1 Immunotherapy for Breast Cancer Treatment
点击查看 >>
Author：
Cunqing Kong, Banghao Xu, Guanhua Qiu, Meng Wei, Mengqi Zhang, Shengxian Bao, Jiali Tang, Lequn Li, JunJie Liu
IF：
7.0330
Publish_to：
International Journal of Nanomedicine
PMID：
36419717
Single-cell RNA sequencing reveals cell landscape following antimony exposure during spermatogenesis in Drosophila testes
点击查看 >>
Author：
Yu Jun, Fu Yangbo, Li Zhiran, Huang Qiuru, Tang Juan, Sun Chi, Zhou Peiyao, He Lei, Sun Feiteng, Cheng Xinmeng, Ji Li, Yu Hao, Shi Yi, Gu Zhifeng, Sun Fei, Zhao Xinyuan
IF：
7.0000
Publish_to：
Cell Death Discovery
PMID：
36894529
Cell membrane camouflaged Cu-doped mesoporous polydopamine for combined CT/PTT/CDT synergistic treatment of breast cancer
点击查看 >>
Author：
Di Meng, Shuoye Yang, Lin Ju, Jinpeng Wang, Yanan Yang, Lu Zhang, Lan Cui
IF：
6.9000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
39383733
Single-cell RNA sequencing analysis to evaluate antimony exposure effects on cell-lineage communications within the Drosophila testicular niche
点击查看 >>
Author：
Hongliang Cui, Qiuru Huang, Jiaxin Li, Peiyao Zhou, Zihan Wang, Jiaying Cai, Chenrui Feng, Xiaonan Deng, Han Gu, Xuxin He, Juan Tang, Xiaoke Wang, Xinyuan Zhao, Jun Yu, Xia Chen
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38184976
Structural Basis for the Binding Selectivity of Human CDY Chromodomains
点击查看 >>
Author：
吕天节
IF：
6.7600
Publish_to：
PMID：
32470319
Hexadecanamide alleviates Staphylococcus aureus-induced mastitis in mice by inhibiting inflammatory responses and restoring blood-milk barrier integrity
点击查看 >>
Author：
Lijuan Bao, Hao Sun, Yihong Zhao, Lianjun Feng, Keyi Wu, Shan Shang, Jiawen Xu, Ruping Shan, Shiyu Duan, Min Qiu, Naisheng Zhang, Xiaoyu Hu, Caijun Zhao, Yunhe Fu
IF：
6.7000
Publish_to：
PLoS Pathogens
PMID：
37948460
Characterization and screening of anti-melanogenesis and anti-photoaging activity of different enzyme-assisted polysaccharide extracts from Portulaca oleracea L.
点击查看 >>
Author：
Xingyu Tao, Xuan Hu, Tongchuan Wu, Dongyue Zhou, Di Yang, Xue Li, Yunhua Fu, Fei Zheng, Hao Yue, Yulin Dai
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
37229889
MeWRKY IIas, Subfamily Genes of WRKY Transcription Factors From Cassava, Play an Important Role in Disease Resistance
点击查看 >>
Author：
Zhu Shousong, Fan Ruochen, Xiong Xi, Li Jianjun, Xiang Li, Hong Yuhui, Ye Yiwei, Zhang Xiaofei, Yu Xiaohui, Chen Yinhua
IF：
6.6270
Publish_to：
Frontiers in Plant Science
PMID：
35720572
Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway
点击查看 >>
Author：
Wei Wanhui, Lu Yuanyuan, Hu Qian, Yin Jinwen, Wang Youwei, Zhang Heng, Zhao Qiu, Liu Lan
IF：
6.6000
Publish_to：
CELLULAR ONCOLOGY
PMID：
37684512
Hydroxy-γ-sanshool from Zanthoxylum bungeanum (prickly ash) induces apoptosis of human colorectal cancer cell by activating P53 and Caspase 8
点击查看 >>
Author：
Zhaojun Chen, Lulin Tan, Xin Feng, Abdel-nasser Singab, Zunguo Lei, Xiong Liu
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
35978957
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction
点击查看 >>
Author：
ZhangChenliang , XuHuanji , TangQiulin , DuanYichun , XiaHongwei , HuangHuixi , YeDi , BiFeng
IF：
6.5000
Publish_to：
EMBO REPORTS
PMID：
39261742
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells
点击查看 >>
Author：
Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, Miao Li, Lin Wei
IF：
6.4000
Publish_to：
mBio
PMID：
37909764
Inhibition of phosphodiesterase 4 attenuates aquaporin 4 expression and astrocyte swelling following cerebral ischemia/reperfusion injury
点击查看 >>
Author：
Kechun Chen, Bingtian Xu, Shuqin Qiu, Lu Long, Qian Zhao, Jiangping Xu, Haitao Wang
IF：
6.2000
Publish_to：
GLIA
PMID：
38785370
2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: In vitro and in vivo validation
点击查看 >>
Author：
Xiaodong Sun, Tengjiao Fan, Guohui Sun, Yue Zhou, Yaxin Huang, Na Zhang, Lijiao Zhao, Rugang Zhong, Yongzhen Peng
IF：
6.1000
Publish_to：
BIOCHEMICAL PHARMACOLOGY
PMID：
35381210
Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis
点击查看 >>
Author：
Qian Hu, Wanhui Wei, Daiqian Wu, Fengxing Huang, Mengting Li, Wenjie Li, Jingwen Yin, Yanan Peng, Yuanyuan Lu, Qiu Zhao, Lan Liu
IF：
6.0810
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
35223839
GLUT1 exacerbates trophoblast ferroptosis by modulating AMPK/ACC mediated lipid metabolism and promotes gestational diabetes mellitus associated fetal growth restriction
点击查看 >>
Author：
Zhang Qin, Yuan Xi, Luan Xiaojin, Lei Ting, Li Yiran, Chu Wei, Yao Qi, Baker Philip N., Qi Hongbo, Li Hui
IF：
6.0000
Publish_to：
MOLECULAR MEDICINE
PMID：
39707215
Rare loss-of-function variants in FLNB cause non-syndromic orofacial clefts
点击查看 >>
Author：
Wenbin Huang, Shiying Zhang, Jiuxiang Lin, Yi Ding, Nan Jiang, Jieni Zhang, Huaxiang Zhao, Feng Chen
IF：
5.9000
Publish_to：
Journal of Genetics and Genomics
PMID：
37003352
Autophagy Is Essential for Neural Stem Cell Proliferation Promoted by Hypoxia
点击查看 >>
Author：
Li Jian, Gong Sheng-Hui, He Yun-Ling, Cao Yan, Chen Ying, Huang Guang-Hai, Wang Yu-Fei, Zhao Ming, Cheng Xiang, Zhou Yan-Zhao, Zhao Tong, Zhao Yong-Qi, Fan Ming, Wu Hai-Tao, Zhu Ling-Ling, Wu Li-Ying
IF：
5.8450
Publish_to：
STEM CELLS
PMID：
36208284
Codelivery of Dihydroartemisinin and Chlorin e6 by Copolymer Nanoparticles Enables Boosting Photodynamic Therapy of Breast Cancer with Low-Power Irradiation
点击查看 >>
Author：
Jia Jing, Chen Wenping, Xu Long, Wang Xuewen, Li Min, Wang Bin, Huang Xiangyu, Wang Tao, Chen Yang, Li Mengdie, Tian Dan, Zhuang Junyang, Lin Xinhua, Li Ning
IF：
5.7630
Publish_to：
Regenerative Biomaterials
PMID：
37250978
Fibroblast ferroptosis is involved in periodontitis-induced tissue damage and bone loss
点击查看 >>
Author：
Lu Xing, Wei Dong, Yilin Chen, Wenyu Dai, Xueling Xiao, Zhongyu Liu, Xiaoqi Zhang, Ding Bai, Hui Xu
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
36700777
Lactobacillus plantarum SMUM211204 Exopolysaccharides Have Tumor-Suppressive Effects on Colorectal Cancer by Regulating Autophagy via the mTOR Pathway
点击查看 >>
Author：
Zixuan Wang, Hengqiu Chen, Shasha Xiong, Xiaoliang Chen, Xuefeng Gao, Pengwei Huang, Jinhu Zou, Hong Cao
IF：
5.7000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
40017402
Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway
点击查看 >>
Author：
Shuhan Li, Zhanpeng Zhu, Tian Lan, Yuhan Wu, Ye Li, Changmin Wang, Wencheng Jian, Shu Yan Yu
IF：
5.6000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37413934
Co-immunization with DNA vaccines encoding yidR and IL-17 augments host immune response against Klebsiella pneumoniae infection in mouse model
点击查看 >>
Author：
Zheng Lv, Xuan Zhang, Kelei Zhao, Lianming Du, Xinrong Wang, Yiwen Chu, Ting Huang
IF：
5.5000
Publish_to：
Virulence
PMID：
38656137
Comprehensive analysis of the regulatory network of blue-light-regulated conidiation and hydrophobin production in Trichoderma guizhouense
点击查看 >>
Author：
Yifan Li, Tingting Sun, Degang Guo, Jia Gao, Jian Zhang, Feng Cai, Reinhard Fischer, Qirong Shen, Zhenzhong Yu
IF：
5.4910
Publish_to：
ENVIRONMENTAL MICROBIOLOGY
PMID：
34472181
Developing a Selection Framework for Zinc Ion-Based Biomaterial Design: Guided by the Biosafety Assessment of ZIF-8 and ZnO
点击查看 >>
Author：
Yilin Mao, Liang Wang, Zhengyi Xu, Wenjia Xie, Yuting Wang, Wei Qiao, Zhou Zhu, Jian Wang
IF：
5.4000
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
38632925
Microfluidic Formulation of Curcumin-Loaded Multiresponsive Gelatin Nanoparticles for Anticancer Therapy
点击查看 >>
Author：
Yu Xia, Ruicheng Xu, Siyuan Ye, Jiaxuan Yan, Piyush Kumar, Peng Zhang, Xiubo Zhao
IF：
5.3950
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
37140447
N-acetylcysteine improves diabetic associated erectile dysfunction in streptozotocin-induced diabetic mice by inhibiting oxidative stress
点击查看 >>
Author：
Zhen Ma, Wenzhen Wang, Chao Pan, Cuiqin Fan, Ye Li, Wenjing Wang, Tian Lan, Fangxin Gong, Changbo Zhao, Zichao Zhao, Shuyan Yu, Mingzhen Yuan
IF：
5.2950
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
35593216
Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes
点击查看 >>
Author：
Zheng Qianwen, Chen Xia, Qiao Chen, Wang Min, Chen Wanyin, Luan Xiaojin, Yan Yidan, Shen Cong, Fang Jie, Hu Xing, Zheng Bo, Wu Yibo, Yu Jun
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
33824283
Kaempferol Improves Exercise Performance by Regulating Glucose Uptake, Mitochondrial Biogenesis, and Protein Synthesis via PI3K/AKT and MAPK Signaling Pathways
点击查看 >>
Author：
Xiaoning Ji, Chaozheng Zhang, Jing Yang, Yaru Tian, Lijuan You, Hui Yang, Yongning Li, Haibo Liu, Deng Pan, Zhaoping Liu
IF：
5.2000
Publish_to：
Foods
PMID：
38611372
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin
点击查看 >>
Author：
Yunfeng Zhou, Dongmei Luo, Junzhuo Shi, Xiaojia Yang, Wangjun Xu, Weiping Gao, Yukun Guo, Qian Zhao, Xinmei Xie, Yangyang He, Guanhua Du, Xiaobin Pang
IF：
5.1950
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
37019163
Size-Controlled Preparation and Behavior Study of Phospholipid Calcium Carbonate Hybrid Nanoparticles
点击查看 >>
Author：
王程
IF：
5.1150
Publish_to：
PMID：
32606663
Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction
点击查看 >>
Author：
Ren Yan-Lin, Jiang Zheng, Wang Jia-Yi, He Qin, Li Si-Xu, Gu Xiao-Jing, Qi Yang-Ran, Zhang Min, Yang Wen-Jie, Cao Bei, Li Jing-Yu, Wang Yi, Chen Yong-Ping
IF：
5.1000
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
38453793
Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy-mediated degradation of damaged mitochondria
点击查看 >>
Author：
Xiaozhou Wang, Hongyan Li, Jie Wang, Huiling Xu, Kun Xue, Xiaoting Liu, Zhizhong Zhang, Jianzhu Liu, Yongxia Liu
IF：
5.0700
Publish_to：
MICROBIOLOGICAL RESEARCH
PMID：
37267814
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis
点击查看 >>
Author：
Qihui Wei, Linlin Chen, Wen Luo, Cailian Chen, Yuqing Shi, Jinmei Xie, Xi Xie, Hai-Bin Luo
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38325798
Degradation protection and enhanced biocompatibility of Mg alloys pretreated with plasma proteins
点击查看 >>
Author：
Xian Wei, Jiajia Meng, Sujie Ma, Yanchun Li, Hong Qing, Xubiao Peng, Qing Zhao
IF：
4.9000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
38327244
Matrix stiffness induces an invasive-dormant subpopulation via cGAS-STING axis in oral cancer
点击查看 >>
Author：
Li Jingyuan, Liu Yu, Jiang Hong, Wang Tao, Li Kan, Lao Xiaomei, Liao Guiqing, Liang Yujie
IF：
4.8030
Publish_to：
Translational Oncology
PMID：
37137218
Proteomic and lipidomic analysis of the mechanism underlying astragaloside IV in mitigating ferroptosis through hypoxia-inducible factor 1α/heme oxygenase 1 pathway in renal tubular epithelial cells in diabetic kidney disease
点击查看 >>
Author：
Jun Liu, Jing Ren, Linlan Zhou, Kaiyue Tan, Donglin Du, Lei Xu, Wenfu Cao, Yudi Zhang
IF：
4.8000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
38972525
Novel hypoxia-induced HIF-1αactivation in asthma pathogenesis
点击查看 >>
Author：
Wan Mengzhi, Yu Qi, Xu Fei, You Lu Xia, Liang Xiao, kang Ren Kang, Zhou Jing
IF：
4.7000
Publish_to：
RESPIRATORY RESEARCH
PMID：
39061007
Differential Disruption of Glucose and Lipid Metabolism Induced by Phthalates in Human Hepatocytes and White Adipocytes
点击查看 >>
Author：
Yaru Tian, Miao Xu, Hailin Shang, Lijuan You, Jing Yang, Xudong Jia, Hui Yang, Yongning Wu, Xingfen Yang, Yi Wan
IF：
4.6000
Publish_to：
Toxics
PMID：
38535947
Red and far-red light improve the antagonistic ability of Trichoderma guizhouense against phytopathogenic fungi by promoting phytochrome-dependent aerial hyphal growth
点击查看 >>
Author：
Tingting Sun, Yifan Li, Jie Li, Jia Gao, Jian Zhang, Reinhard Fischer, Qirong Shen, Zhenzhong Yu
IF：
4.5000
Publish_to：
PLoS Genetics
PMID：
38768261
Oxidized phospholipid POVPC contributes to vascular calcification by triggering ferroptosis of vascular smooth muscle cells
点击查看 >>
Author：
Lihe Lu, Yuanzhi Ye, Yajun Chen, Liyun Feng, Jiali Huang, Qingchun Liang, Zirong Lan, Qianqian Dong, Xiaoyu Liu, Yining Li, Xiuli Zhang, Jing-Song Ou, An Chen, Jianyun Yan
IF：
4.4000
Publish_to：
FASEB JOURNAL
PMID：
38581243
The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages
点击查看 >>
Author：
Zeng Wenyun, Wu Danbin, Sun Yingxin, Suo Yanrong, Yu Qun, Zeng Miao, Gao Qing, Yu Bin, Jiang Xijuan, Wang Yijing
IF：
4.3800
Publish_to：
Scientific Reports
PMID：
34588488
DNA methylation status of DNAJA4 is essential for human erythropoiesis
点击查看 >>
Author：
Hengchao Zhang, Fumin Xue, Huizhi Zhao, Lixiang Chen, Ting Wang, Xiuyun Wu
IF：
4.3570
Publish_to：
Epigenomics
PMID：
36420716
Action of the Nrf2/ARE signaling pathway on oxidative stress in choroid plexus epithelial cells following lanthanum chloride treatment
点击查看 >>
Author：
Jing Sun, Yanshu Zhang, Licheng Yan, Si Liu, Weicheng Wang, Yi Zhu, Weixuan Wang, Shuang Li, Bin He, Lei Wu, Lijin Zhang
IF：
4.3360
Publish_to：
JOURNAL OF INORGANIC BIOCHEMISTRY
PMID：
35303612
Resveratrol Upregulates miR‐124‐3p Expression to Target DAPK1, Regulating the NLRP3/Caspase‐1/GSDMD Pathway to Inhibit Pyroptosis and Alleviate Spinal Cord Injury
点击查看 >>
Author：
Daohui Li, Yongwen Dai, Zhengtao Li, Hangchuan Bi, Haotian Li, Yongquan Wang, Yuan Liu, Xinpeng Tian, Lingqiang Chen
IF：
4.3000
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
39833100
HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model
点击查看 >>
Author：
Dan Li, Xian Xie, Zishun Zhan, Nannan Li, Ni Yin, Shikun Yang, Jishi Liu, Jianwen Wang, Zhi Li, Bin Yi, Hao Zhang, Wei Zhang
IF：
4.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
38871033
Rapeseed peptide inhibits HepG2 cell proliferation by regulating the mitochondrial and P53 signaling pathways
点击查看 >>
Author：
Keer Ma, Zhigao Wang, Xingrong Ju, Jiankang Huang, Rong He
IF：
4.1250
Publish_to：
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
PMID：
36168817
Exposure to Titanium Dioxide Nanoparticles Leads to Specific Disorders of Spermatid Elongation via Multiple Metabolic Pathways in Drosophila Testes
点击查看 >>
Author：
Xinmeng Cheng, Ting Jiang, Qiuru Huang, Li Ji, Jiaxin Li, Xiuwen Kong, Xiaoqi Zhu, Xuxin He, Xiaonan Deng, Tong Wu, Hao Yu, Yi Shi, Lin Liu, Xinyuan Zhao, Xiaorong Wang, Hao Chen, Jun Yu
IF：
4.1000
Publish_to：
ACS Omega
PMID：
38854533
Electrical stimulation induced structural 3D human engineered neural tissue with well-developed neuronal network and functional connectivity
点击查看 >>
Author：
Xiaoting Meng, Xiyao Yu, Yingli Lu, Zhe Pei, Guoqiang Wang, Mingran Qi, Rongrong Liu, Jiaying Zhou, Xiaopin Guo, Zhengjie Zhou, Fang Wang
IF：
4.0000
Publish_to：
Journal of Neural Engineering
PMID：
37433290
Phlorizin from sweet tea inhibits the progress of esophageal cancer by antagonizing the JAK2/STAT3 signaling pathway
点击查看 >>
Author：
Zhenxian Jia, Yuning Xie, Hongjiao Wu, Zhuo Wang, Ang Li, Ze Li, Zhenbang Yang, Zhi Zhang, Zhaobin Xing, Xuemei Zhang
IF：
3.9060
Publish_to：
ONCOLOGY REPORTS
PMID：
34036398
Wnt6 regulates the homeostasis of the stem cell niche via Rac1-and Cdc42-mediated noncanonical Wnt signalling pathways in Drosophila testis
点击查看 >>
Author：
Min Wang, Xiaojin Luan, Yidan Yan, Qianwen Zheng, Wanyin Chen, Jie Fang
IF：
3.9050
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
33582096
Replication of standard bovine viral diarrhea strain OregonC24Va induces endoplasmic reticulum stress–mediated apoptosis of bovine trophoblast cells
点击查看 >>
Author：
Yuan Naihan, Song Quanjiang, Jin Yan, Zhang Zhenhao, Wu Zheng, Sheng Xihui, Qi Xiaolong, Xing Kai, Xiao Longfei, Wang Xiangguo
IF：
3.8270
Publish_to：
CELL STRESS & CHAPERONES
PMID：
36441379
Y/X-Chromosome-Bearing Sperm Shows Elevated Ratio in the Left but Not the Right Testes in Healthy Mice
点击查看 >>
Author：
Chengqing Hu, Jiangcheng Shi, Yujing Chi, Jichun Yang, Qinghua Cui
IF：
3.8170
Publish_to：
Life-Basel
PMID：
34833095
Approaches to selective and potent inhibition of glioblastoma by vanadyl complexes: Inducing mitotic catastrophe and methuosis
点击查看 >>
Author：
Sha Xu, Huixue Liu, Xin Li, Jingyan Zhao, Jiayu Wang, Debbie C. Crans, Xiaoda Yang
IF：
3.8000
Publish_to：
JOURNAL OF INORGANIC BIOCHEMISTRY
PMID：
38761580
SENP1-mediated SUMOylation of SIRT1 affects glioma development through the NF-百B pathway
点击查看 >>
Author：
Xin Liu, Shenglin Zhang, Yi Dong, Yunpeng Xie, Qingshan Li
IF：
3.7000
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
37866458
3-N-butylphthalide attenuates neuroinflammation in rotenone-induced Parkinson’s disease models via the cGAS-STING pathway
点击查看 >>
Author：
Yuqian Liu, Ruonan Duan, Peizheng Li, Bohan Zhang, Yiming Liu
IF：
3.5000
Publish_to：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
PMID：
38315064
Exosomal miR-155-5p Facilitates Lipopolysaccharide Transport and Foam Cell Formation: A Novel Link Between Periodontitis and Atherosclerosis
点击查看 >>
Author：
Wen-Wen Yang, Qing-Xiang Li, Fei Wang, Xin-Ran Zhang, Xian-Li Zhang, Meng Wang, Dong Xue, Ying Zhao, Lu Tang
IF：
3.4000
Publish_to：
JOURNAL OF PERIODONTAL RESEARCH
PMID：
39604303
Coumestrol facilitates apoptosis in colorectal cancer cells by interacting with ZIP8 protein via the ferroptosis pathway
点击查看 >>
Author：
Geng Jing, Wang Yingying, Lv Fengchun, Yu Xiaomin, Gong Mingyu, Zhang Jie, Zhao Zicheng, Zhu Xiaoyue, Zhang Xiaoyu, Yang Jian, Yang Xiu-An
IF：
3.3000
Publish_to：
Journal of Cancer
PMID：
39006076
Asiatic acid inhibits rheumatoid arthritis fibroblast-like synoviocyte growth through the Nrf2/HO-1/NF-κB signaling pathway
点击查看 >>
Author：
Li Zhang, Zhi-ning Liu, Xi-yuan Han, Xin Liu, Yang Li
IF：
3.2000
Publish_to：
Chemical Biology & Drug Design
PMID：
38477392
Sequence-dependent effects of hematoporphyrin derivatives (HPD) photodynamic therapy and cisplatin on lung adenocarcinoma cells
点击查看 >>
Author：
Nana Li, Shichao Cui, Aizhen Yang, Baohong Xiao, Yiwei Cao, Xiaohui Yang, Cunzhi Lin
IF：
3.1000
Publish_to：
Photodiagnosis and Photodynamic Therapy
PMID：
38679153
Network pharmacology and in vitro experiments reveal sophoridine-induced apoptosis and G1 phase arrest via ROS-dependent PI3K/Akt/FoxO3a pathway activation in human bladder cancer cells
点击查看 >>
Author：
Yao Su, Lin Chen, Jin Yang
IF：
3.0000
Publish_to：
Chemical Biology & Drug Design
PMID：
38346772
miR‑188‑5p promotes oxaliplatin resistance by targeting RASA1 in colon cancer cells
点击查看 >>
Author：
Xijia Zhu, Xishun Luo, Zhike Song, Shiyu Jiang, Xiangkai Long, Xueyuan Gao, Xinyang Xie, Laijian Zheng, Haipeng Wang
IF：
2.9670
Publish_to：
Oncology Letters
PMID：
33968197
Regulation of H9C2 cell hypertrophy by 14-3-3η via inhibiting glycolysis
点击查看 >>
Author：
Sha Wan, Songhao Wang, Xianfei Yang, Yalan Cui, Heng Guan, Wenping Xiao, Fang Liu
IF：
2.9000
Publish_to：
PLoS One
PMID：
39038022
Cucurbit[7]uril enhances photosensitization of porphyrins in Neuroblastoma cells
点击查看 >>
Author：
XiaoyuLiaBoXiaoaYanGuoaYanXiaobSongXiaoa
IF：
2.8950
Publish_to：
Photodiagnosis and Photodynamic Therapy
PMID：
30648639
Quercetin exerts anti-tumor immune mechanism by regulating IL-6/JAK2/STAT3 signaling pathway to deplete Treg cells
点击查看 >>
Author：
Yupei Liao, Xiaoqing Xie, Chu Zhang, Haijing Zhong, Luchen Shan, Pei Yu, Lipeng Xu
IF：
2.8000
Publish_to：
TOXICON
PMID：
38714236
LncRNA MALAT1 Regulates USP22 Expression Through EZH2-Mediated H3K27me3 Modification to Accentuate Sepsis-Induced Myocardial Dysfunction
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Author：
Xu Hong, Ye Wei, Shi Baochang
IF：
2.7550
Publish_to：
Cardiovascular Toxicology
PMID：
35726125
Deoxynivalenol and zearalenone: Different mycotoxins with different toxic effects in donkey (Equus asinus) endometrial epithelial cells
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Author：
Jun-Lin Song, Yu-Jiang Sun, Gui-Qin Liu, Guo-Liang Zhang
IF：
2.7400
Publish_to：
THERIOGENOLOGY
PMID：
34879314
LINC01936 inhibits the proliferation and metastasis of lung squamous cell carcinoma probably by EMT signaling and immune infiltration
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Author：
Qinqin Tian, Xiyao Liu, Ang Li, Hongjiao Wu, Yuning Xie, Hongmei Zhang, Fengjun Wu, Yating Chen, Congcong Bai, Xuemei Zhang
IF：
2.7000
Publish_to：
PeerJ
PMID：
38084139
The Role and Mechanism of Nicotinamide Riboside in Oxidative Damage and a Fibrosis Model of Trabecular Meshwork Cells
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Author：
Yuping Zeng, Yijun Lin, Juhua Yang, Xiaohui Wang, Yihua Zhu, Biting Zhou
IF：
2.6000
Publish_to：
Translational Vision Science & Technology
PMID：
38546981
In vitro induction of anti‑lung cancer immune response by the A549 lung cancer stem cell lysate‑sensitized dendritic cell vaccine
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Author：
Letian Chen, Wei Rao, Yujuan Chen, Junping Xie
IF：
2.5000
Publish_to：
Oncology Letters
PMID：
39328277
Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking
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Author：
Huiling Xu, Xiaozhou Wang, Zhizhong Zhang, Jiaqing Hu, Yongtao Yu, Jiandong Wang, Yongxia Liu, Jianzhu Liu
IF：
2.4000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
38626624
Exploring miR-21 as a key regulator in two distinct approaches of bone marrow stromal cells differentiation into Schwann-like cells
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Author：
Yu-Mei Liu, He-Ying Wang, Cai-Hong Wei, Jun-Ping Li, Ying Wang, Wen-Zhi Ma, Hua Jia
IF：
2.3000
Publish_to：
SYNAPSE
PMID：
38779935
Gentiopicroside Alleviates Atherosclerosis by Suppressing Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation in Vascular Endothelial Cells via SIRT1/Nrf2 Pathway
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Author：
Li Zhu-qing, Zhang Feng, Li Qi, Wang Li, Sun Xiao-qiang, Li Chao, Yin Xue-mei, Liu Chun-lei, Wang Yan-xin, Du Xiao-yu, Lu Cheng-zhi
IF：
2.2000
Publish_to：
Chinese Journal of Integrative Medicine
PMID：
39671057
A Key regulatory protein QRICH2 governing sperm function with profound antioxidant properties, enhancing sperm viability
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Author：
Guohui Zhang, Dongsheng Xiong, Fei Ye, Yuhong Zhao, Xinrong Du, Weiwei Zhi, Fulin Liu, Jiuzhi Zeng, Wenming Xu, Weixin Liu, Yi Shi
IF：
2.1000
Publish_to：
Reproductive Biology
PMID：
38772286
Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome
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Author：
JINGJING CHEN, DAN WANG, ZEQUN WANG, MENGYUAN HAN, HOUQING YIN, WENTING ZHOU, RIBAI YAN, YAN PAN
IF：
2.0000
Publish_to：
ONCOLOGY RESEARCH
PMID：
38686054
The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta
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Author：
Kunhua ZHENG, Longfei XIAO, Naihan YUAN, Xihui SHENG, Xiaolong QI, Yingqiu WANG, Chang CHEN, Kaijun GUO, Lin YANG, Bingying LIU, Xiangguo WANG
IF：
1.9000
Publish_to：
JOURNAL OF REPRODUCTION AND DEVELOPMENT
PMID：
39662929
Effect of Xanthii Fructus alcohol extract on proliferation and apoptosis of HFLS-RA and its mechanism
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Author：
Jiang Hai, Yu Huan, Zheng Senwang, Wang Xuejiao, Hou Ajiao, Kuang Haixue, Yang Liu
IF：
1.8170
Publish_to：
MEDICINE
PMID：
36596012
Protocol for visualizing the chromatin assembly properties of epigenetic protein complexes via an HTM module-mediated artificial tethering system
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Author：
Shanli Guan, Jiajia Tang, Cuixia Di, Bo Cheng
IF：
1.3000
Publish_to：
STAR Protocols
PMID：
39879359
技术问答
（2）
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你好，染色液放在4度36h还能用吗2024-11-26 15:47:00
您好，可以先做下预实验检测下试剂效果，如果发现有明显衰减，应弃用
能用于真菌细胞核染色吗?2023-08-11 12:36:09
您好，不建议，细菌的壁结构通透性较差染料较难进入。