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Hoechst 33342
CAS:No.875756-97-1
英文名称:Hoechst 33342
分子式:C27H28N6O·3HCl
分子量:561.9
储存条件:Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year
纯度:≥98%
产品简介
| CAS | No.875756-97-1 |
| 英文名称 | Hoechst 33342 |
| 别名 | bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride |
| 分子式 | C27H28N6O·3HCl |
| 分子量 | 561.9 |
| 溶解性 | Soluble in Water/DMSO ＞ 1mg/mL |
| 纯度 | ≥98% |
| 外观(性状) | Light yellow to green yellow Solid |
| 储存条件 | Powder:-20℃，1 year;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| EC | EINECS 245-691-1 |
| MDL | MFCD00166996 |
| SMILES | CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(OCC)C=C6)N5)=C4)N3)=C2)CC1 |
| InChIKey | JABNPSKWVNCGMX-UHFFFAOYSA-N |
| InChI | InChI=1S/C27H28N6O.3ClH/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33;;;/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31);3*1H |
| PubChem CID | 16760503 |
| 背景说明 | 是一种可以穿透细胞膜的蓝色荧光染料,它在嵌入双链 DNA 后释放强烈的蓝色荧光,对细胞的毒性较低。 |
| 规格 | 10mg 10mM*1mL in DMSO 10mM*1mL in Water 50mg |
| 单位 | 瓶 |
是一种可以穿透细胞膜的蓝色荧光染料，它在嵌入双链 DNA 后释放强烈的蓝色荧光，对细胞的毒性较低。Hoechst 33342染色常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33342也常用于普通的细胞核染色，或常规的DNA染色。Hoechst 33342的最大激发波长为346nm，最大发射波长为460nm；Hoechst 33342和双链DNA结合后，最大激发波长为350nm，最大发射波长为461nm。
使用说明（仅供参考）：
1. 对于固定的细胞或组织：
a. 对于细胞或组织样品，固定后，适当洗涤去除固定剂。随后如果需要进行免疫荧光染色，则先进行免疫荧光染色，染色完毕后再按后续步骤进行Hoechst 33342染色。如果不需要进行其它染色，则直接进行后续的Hoechst 33342染色。
b. 对于贴壁细胞或组织切片，加入少量Hoechst 33342染色液，覆盖住样品即可；对于悬浮细胞，至少加入待染色样品3倍体积的染色液，混匀。室温放置3-5分钟。
c. 吸除Hoechst 33342染色液，用TBST、PBS或生理盐水洗涤2-3次，每次3-5分钟。
d. 直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时，会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
2. 对于活细胞或组织：
a. 加入适当量Hoechst 33342染色液，必须充分覆盖住待染色的样品，通常对于六孔板一个孔需加入1mL染色液，对于96孔板一个孔需加入100微升染色液。
b. 在适宜于细胞培养的温度下培养20-30分钟。弃染色液，用PBS或培养液洗涤2-3次即可进行荧光检测。
注意事项：
荧光染料都存在淬灭的问题，为减缓荧光淬灭可以使用抗荧光衰减封片剂。建议染色后尽量当天完成检测，活细胞或组织染色后应立即观察。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用本产品的案例（仅供参考）
In Vitro
Cell（LUAD cell， 10 ug/ml Hochest 33342， RT， 20min, PBS洗涤）
Cells（Imaging flow cytometry，Human or mouse T cells）
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
实验图
暂无详情
Chen WJ, et al. J Endod. 2021 Jun;47(6)961-969
Liu Yanhong,et al. ACS applied materials & interfaces,2020,12(13)
Wu X, Jiao Z, Zhang J, Li F, Li Y. J Nanobiotechnology. 2023 Apr 11;21(1)126.
Chen Q, et al. Biomaterials. 2020 Apr 3;251120008.
Ping Y,et al.Immunity. 2024 Sep 10;57(9):2122-2139.e9. doi: 10.1016/j.immuni.2024.08.003.
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9.4000
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
PMID：
39236435
In vitro/vivo antitumor study of modified-chitosan/carboxymethyl chitosan “boosted” charge-reversal nanoformulation
点击查看 >>
Author：
Lin Li, Peng Zhang, Congcong Li, Yan Guo, Kaoxiang Sun
IF：
9.3810
Publish_to：
CARBOHYDRATE POLYMERS
PMID：
34294300
Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy
点击查看 >>
Author：
Shengmei Wang, Xuanjun Liu, Minghua Yang, Linqi Ouyang, Jinsong Ding, Shengfeng Wang, Wenhu Zhou
IF：
9.2730
Publish_to：
Asian Journal of Pharmaceutical Sciences
PMID：
36101893
Spatiotemporal Concurrent Liberation of Cytotoxins from Dual-Prodrug Nanomedicine for Synergistic Antitumor Therapy
点击查看 >>
Author：
Liuwei Zhang, Ming Qian, Hongyan Cui, Shuang Zeng, Jingyun Wang, Qixian Chen
IF：
9.2290
Publish_to：
ACS Applied Materials & Interfaces
PMID：
33525873
Colchicine attenuates the electrical remodeling of post-operative atrial fibrillation through inhibited expression of immune-related hub genes and stabilization of microtubules
点击查看 >>
Author：
Hangying Ying; Wenpu Guo; Xiaomei Tang; Jun Pan; P
IF：
9.2000
Publish_to：
International Journal of Biological Sciences
PMID：
37324937
Enterococcus faecalis-Induced Macrophage Necroptosis Promotes Refractory Apical Periodontitis
点击查看 >>
Author：
Xingzhu Dai, Rongyang Ma, Weiyi Jiang, Zilong Deng, Lijuan Chen, Yuee Liang, Longquan Shao, Wanghong Zhao
IF：
9.0430
Publish_to：
Microbiology Spectrum
PMID：
35708336
Mucoadhesive phenylboronic acid conjugated chitosan oligosaccharide-vitamin E copolymer for topical ocular delivery of voriconazole: Synthesis, in vitro/vivo evaluation, and mechanism
点击查看 >>
Author：
Xingchen Sun, Yuhui Sheng, Keke Li, Sixiang Sai, Jie Feng, Yajing Li, Jiasong Zhang, Jingtian Han, Baocheng Tian
IF：
8.9470
Publish_to：
Acta Biomaterialia
PMID：
34757228
Feasibility of cRGD conjugation at 5′-antisense strand of siRNA by phosphodiester linkage extension
点击查看 >>
Author：
Xinyang Zhou, Yufei Pan, Lijia Yu, Jing Wu, Zheng Li, Huantong Li, Zhu Guan, Xinjing Tang, Zhenjun Yang
IF：
8.8860
Publish_to：
Molecular Therapy-Nucleic Acids
PMID：
34589281
Programmable scaffolds with aligned porous structures for cell cultured meat
点击查看 >>
Author：
Yichun Chen, Wenhui Zhang, Xi Ding, Shijie Ding, Changbo Tang, Xianming Zeng, Jie Wang, Guanghong Zhou
IF：
8.8000
Publish_to：
FOOD CHEMISTRY
PMID：
37562260
Amplified Photoacoustic Signal and Enhanced Photothermal Conversion of Polydopamine-Coated Gold Nanobipyramids for Phototheranostics and Synergistic Chemotherapy
点击查看 >>
Author：
Liu Y; Li Z; Yin Z; Zhang H; Gao Y; Huo G; Wu A; Z
IF：
8.7480
Publish_to：
ACS Appl Mater Interfaces
PMID：
32153178
Tumor-targeting Nanomaterials Based on Metal-organic Frameworks Mediate Tumor Immunotherapy by Promoting Cuproptosis and Pyroptosis in Hepatocellular Carcinoma Cells
点击查看 >>
Author：
Xiaoyuan Yi, Huaying Xie, Kunzhao Huang, Jianzhang Luo, Wen Li, Qingyu Zeng, Feifei He, Wuxiang Shi, Duo Wang, Liyan Wang
IF：
8.7000
Publish_to：
Materials Today Bio
PMID：
40275951
Tetrahedral framework nucleic acids inhibit pathological neovascularization and vaso-obliteration in ischaemic retinopathy via PI3K/AKT/mTOR signalling pathway
点击查看 >>
Author：
Xiaodi Zhou, Yanting Lai, Xiaoxiao Xu, Qiong Wang, Limei Sun, Limei Chen, Jiajie Li, Rong Li, Delun Luo, Yunfeng Lin, Xiaoyan Ding
IF：
8.5000
Publish_to：
CELL PROLIFERATION
PMID：
36694349
Suppression of lncRNA NLRP3 inhibits NLRP3-triggered inflammatory responses in early acute lung injury
点击查看 >>
Author：
Luo Deqiang, Dai Wei, Feng Xiaojin, Ding Chengzhi, Shao Qiang, Xiao Rui, Zhao Ning, Peng Wei, Yang Ying, Cui Yamei, Liu Fen, Qian Kejian
IF：
8.4690
Publish_to：
Cell Death & Disease
PMID：
34599154
Programmed pH-responsive core–shell nanoparticles for precisely targeted therapy of ulcerative colitis
点击查看 >>
Author：
Guangshuai Zhang, Wen Han, Peixu Zhao, Zijun Wang, Mo Li, Xiaofan Sui, Yanhua Liu, Baocheng Tian, Zhonggui He, Qiang Fu
IF：
8.3070
Publish_to：
Nanoscale
PMID：
36625215
Aggregation-Induced Emission CN-Based Nanoparticles to Alleviate Hypoxic Liver Fibrosis via Triggering HSC Ferroptosis and Enhancing Photodynamic Therapy
点击查看 >>
Author：
Ming-Xuan Liu, Yu-Ting Cai, Ruo-Jia Wang, Peng-Fei Zhu, Yan-Chao Liu, Hao Sun, Yong Ling, Wei-Zhong Zhu, Jing Chen, Xiao-Ling Zhang
IF：
8.3000
Publish_to：
ACS Applied Materials & Interfaces
PMID：
38888460
Vincamine as an agonist of G-protein-coupled receptor 40 effectively ameliorates diabetic peripheral neuropathy in mice
点击查看 >>
Author：
Xu Jia-wen, Xu Xu, Ling Yun, Wang Yan-chun, Huang Yu-jie, Yang Juan-zhen, Wang Jia-ying, Shen Xu
IF：
8.2000
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
37580494
Selenium nanoparticles alleviates cadmium induced hepatotoxicity by inhibiting ferroptosis and oxidative stress in vivo and in vitro
点击查看 >>
Author：
Chunyan Shao, Tongwang Luo, Shujie Wang, Zhuoyue Li, Xiaoqiang Yu, Ya Wu, Sheng Jiang, Bin Zhou, Quanjiang Song, Shengzhe Song, Xiaodu Wang, Houhui Song
IF：
8.1000
Publish_to：
CHEMOSPHERE
PMID：
39097112
Quantum Dots Tracking Endocytosis and Transport of Proteins Displayed by Mammalian Cells
点击查看 >>
Author：
Meng-Qian Zhang, Zhi-Gang Wang, Dan-Dan Fu, Ju-Mei Zhang, Hao-Yang Liu, Shu-Lin Liu, Dai-Wen Pang
IF：
8.0080
Publish_to：
ANALYTICAL CHEMISTRY
PMID：
35581735
Zeolitic Imidazolate Framework (ZIF-8) Decorated Iron Oxide Nanoparticles Loaded Doxorubicin Hydrochloride for Osteosarcoma Treatment - in vitro and in vivo Preclinical Studies
点击查看 >>
Author：
Wenbo Wu, Xiaoli Yu, Jiaxiang Sun, Yuanyuan Han, Yuanye Ma, Guoqing Zhang, Qingming Ma, Qiang Li, Hongfei Xiang
IF：
8.0000
Publish_to：
International Journal of Nanomedicine
PMID：
38164268
Single-cell transcriptome characteristics of testicular terminal epithelium lineages during aging in the Drosophila
点击查看 >>
Author：
Xia Chen, Yujuan Qi, Qiuru Huang, Chi Sun, Yanli Zheng, Li Ji, Yi Shi, Xinmeng Cheng, Zhenbei Li, Sen Zheng, Yijuan Cao, Zhifeng Gu, Jun Yu
IF：
7.8000
Publish_to：
AGING CELL
PMID：
38044573
Enhancing stem cell therapy efficacy with functional lignin modified cerium-iron nanozyme through magnetic resonance imaging tracking and apoptosis protection in inflammatory environment
点击查看 >>
Author：
Hanyu Huang, Lina Zhang, Pek Yin Michelle Yew, Sigit Sugiarto, Ruiping Zhou, Dan Kai, Zhiyong Wang
IF：
7.7000
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
38782320
Dual-responsive nano-prodrug micelles for MRI-guided tumor PDT and immune synergistic therapy
点击查看 >>
Author：
Hui Guo, Fangzhe Liu, Enqi Liu, Shanshan Wei, Wenbo Sun, Baoqiang Liu, Guoying Sun, Lehui Lu
IF：
7.5710
Publish_to：
Journal of Materials Chemistry B
PMID：
35583206
Shrimp Plasma CREG Is a Hemocyte Activation Factor
点击查看 >>
Author：
Huang Zhiqi, Yang Peng, Wang Fan
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
34484206
Ganoderenic acid D-loaded functionalized graphene oxide-based carrier for active targeting therapy of cervical carcinoma
点击查看 >>
Author：
Jiahui Lu, Anqiang Zhang, Fuming Zhang, Robert J. Linhardt, Zhihui Zhu, Yanzi Yang, Tinghuang Zhang, Zhibin Lin, Su Zhang, Huajun Zhao, Peilong Sun
IF：
7.5000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
37269813
Mitochondrial dysfunction in cumulus cells is related to decreased reproductive capacity in advanced-age women
点击查看 >>
Author：
Xinmei Lu, Yubing Liu, Jun Xu, Xiang Cao, Doudou Zhang, Miao Liu, Suying Liu, Xi Dong, Huijuan Shi
IF：
7.4900
Publish_to：
FERTILITY AND STERILITY
PMID：
35637023
NS1619 Alleviate Brain-Derived Extracellular Vesicle-Induced Brain Injury by Regulating BKca Channel and Nrf2/HO-1/NF-ĸB Pathway.
点击查看 >>
Author：
Yalong Gao, Hejun Zhang, Xiaotian Li, Lei Li, Fanjian Li, Tuo Li, Ruilong Peng, Cong Wang, Jiwei Wang, Xiao Liu, Shu Zhang, Jianning Zhang
IF：
7.3100
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
36466093
Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis
点击查看 >>
Author：
Xu-Yang Chen, Yan-Chao Dong, Yuan-Yuan Yu, Man Jiang, Wen-Jie Bu, Ping Li, Zhi-Jie Sun, De-Li Dong
IF：
7.3000
Publish_to：
BRITISH JOURNAL OF PHARMACOLOGY
PMID：
37428102
All-trans retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating ferroptosis
点击查看 >>
Author：
Yanting Sun, Yun He, Jishuang Tong, Daijiang Liu, Haodong Zhang, Tongchuan He, Yang Bi
IF：
7.2430
Publish_to：
Genes & Diseases
PMID：
36157492
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice
点击查看 >>
Author：
Zhu Dan-yang, Lu Jian, Xu Rui, Yang Juan-zhen, Meng Xiang-rui, Ou-Yang Xing-nan, Yan Qiu-ying, Nie Rui-fang, Zhao Tong, Chen Yi-di, Lu Yin, Zhang Yi-nan, Li Wen-jun, Shen Xu
IF：
7.1690
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
35260821
Cardiac Resolvin D2 ameliorates sepsis-induced cardiomyopathy via inhibiting Caspase-11/GSDMD dependent pyroptosis
点击查看 >>
Author：
Wen-wu Zhang, Shun-shun Wang, Yang-dong Ding, Xin-yi Wu, Ting Chen, Ye Gao, Sheng-wei Jin, Pu-hong Zhang
IF：
7.1000
Publish_to：
FREE RADICAL BIOLOGY AND MEDICINE
PMID：
38437927
Mitochondrial targeted hierarchical drug delivery system based on HA-modified liposomes for cancer therapy
点击查看 >>
Author：
Huiting Chen, Zhou Fang, Mengdi Song, Kehai Liu
IF：
7.0880
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
35963128
Combination of the endophytic manganese-oxidizing bacterium Pantoea eucrina SS01 and biogenic Mn oxides: An efficient and sustainable complex in degradation and detoxification of malachite green
点击查看 >>
Author：
Yuankai Sun, Yonggang Zhang, Wenzhe Li, Wenchang Zhang, Zhenlu Xu, Meixue Dai, Guoyan Zhao
IF：
7.0860
Publish_to：
CHEMOSPHERE
PMID：
33971420
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion
点击查看 >>
Author：
Zhao Chen, Liang Fangte, Ye Mengling, Wu Siyi, Qin Yi, Zhao Lu, Zhang Lu, He Jing, Cen Liming, Lin Fei
IF：
7.0000
Publish_to：
Cell Death Discovery
PMID：
37794018
pH-Sensitive Polymeric Vesicles for GOx/BSO Delivery and Synergetic Starvation-Ferroptosis Therapy of Tumor
点击查看 >>
Author：
Yang Luo, Peng Yan, Xinyang Li, Jianwen Hou, Yi Wang, Shaobing Zhou
IF：
6.9880
Publish_to：
BIOMACROMOLECULES
PMID：
34533297
Reversible Chemical Protein Modification to Endogenous Glutathione and Its Utilities in the Manufacture of Transcellular Pro-Enzymes
点击查看 >>
Author：
Yu Wang, Shuang Zeng, Hongyan Cui, Haidong Li, Zhen Li, Jingyun Wang, Qixian Chen
IF：
6.9780
Publish_to：
BIOMACROMOLECULES
PMID：
35471918
Oligopeptide-strategy of targeting at adipose tissue macrophages using ATS-9R/siCcl2 complex for ameliorating insulin resistance in GDM
点击查看 >>
Author：
Min Wang, Xuyang Chen, Yanshan Shang, Bingnan Chen, Hao Chen, Linwei Zhou, Hongli Li, Dan Zhang, Bailong Tao, Xiaobo Zhou, Hua Zhang
IF：
6.9000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38776680
Preliminary study on 24p3 / neutrophil gelatinase-associated lipocalin (NGAL) ferroptosis inhibition in renal tubular epithelial cells
点击查看 >>
Author：
Yi-Jue Song, Qing-Ya Zhang, Li-Jun Wang, Min-Chao Cai, Jin-Fang Bao, Qing Yu
IF：
6.8320
Publish_to：
Bioengineered
PMID：
35577350
Conditioned medium derived from 3D tooth germs: A novel cocktail for stem cell priming and early in vivo pulp regeneration
点击查看 >>
Author：
Tengfei Zhou, Mingdeng Rong, Zijie Wang, Hongxing Chu, Chuying Chen, Jiayi Zhang, Zhihui Tian
IF：
6.8310
Publish_to：
CELL PROLIFERATION
PMID：
34585454
Iodinated cyanine dye-based nanosystem for synergistic phototherapy and hypoxia-activated bioreductive therapy
点击查看 >>
Author：
Yunxia Dong, Ling Zhou, Zijun Shen, Qingming Ma, Yifan Zhao, Yong Sun, Jie Cao
IF：
6.8190
Publish_to：
DRUG DELIVERY
PMID：
35001784
Deep-Learning-Driven Discovery of SN3–1, a Potent NLRP3 Inhibitor with Therapeutic Potential for Inflammatory Diseases
点击查看 >>
Author：
Cheng Shi, Tongfei Gao, Weiping Lyu, Bo Qiang, Yanming Chen, Qixuan Chen, Liangren Zhang, Zhenming Liu
IF：
6.8000
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
PMID：
39302813
JAK/STAT signaling regulated intestinal regeneration defends insect pests against pore-forming toxins produced by Bacillus thuringiensis
点击查看 >>
Author：
Zeyu Wang, Yanchao Yang, Sirui Li, Weihua Ma, Kui Wang, Mario Soberón, Shuo Yan, Jie Shen, Frederic Francis, Alejandra Bravo, Jie Zhang
IF：
6.7000
Publish_to：
PLoS Pathogens
PMID：
38236820
Selective Anti-melanoma Effect of Phosphothioated Aptamer Encapsulated by Neutral Cytidinyl/Cationic Lipids
点击查看 >>
Author：
Wu Jing, Wang Shuhe, Li Xiang, Zhang Qi, Yang Jie, Ma Yuan, Guan Zhu, Yang Zhenjun
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
34262898
2-(2-phenylethyl)chromone-enriched extract of the resinous heartwood of Chinese agarwood (Aquilaria sinensis) protects against taurocholic acid-induced gastric epithelial cells apoptosis through Perk/eIF2α/CHOP pathway
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Author：
Jiale Ma, Huixia Huo, Hang Zhang, Lingxiao Wang, Yingxin Meng, Fengyu Jin, Xinyu Wang, Yimu Zhao, Yunfang Zhao, Pengfei Tu, Yuelin Song, Jiao Zheng, Jun Li
IF：
6.6560
Publish_to：
PHYTOMEDICINE
PMID：
35104763
Combined Effects of Anti-PD-L1 and Nanosonodynamic Therapy on HCC Immune Activation in Mice: An Investigation
点击查看 >>
Author：
Meng Wei, Xiaobo Wang, Yunhai Mo, Cunqing Kong, Mengqi Zhang, Guanhua Qiu, Zhihong Tang, Jie Chen, Feixiang Wu
IF：
6.6000
Publish_to：
International Journal of Nanomedicine
PMID：
39050875
Iron-doxorubicin prodrug loaded liposome nanogenerator programs multimodal ferroptosis for efficient cancer therapy
点击查看 >>
Author：
Yinxian Yang, Shiyi Zuo, Linxiao Li, Xiao Kuang, Jinbo Li, Bingjun Sun, Shujun Wang, Zhonggui He, Jin Sun
IF：
6.5980
Publish_to：
Asian Journal of Pharmaceutical Sciences
PMID：
35027953
Hydroxy-γ-sanshool from Zanthoxylum bungeanum (prickly ash) induces apoptosis of human colorectal cancer cell by activating P53 and Caspase 8
点击查看 >>
Author：
Zhaojun Chen, Lulin Tan, Xin Feng, Abdel-nasser Singab, Zunguo Lei, Xiong Liu
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
35978957
Design and fabrication of an integrated 3D dynamic multicellular liver-on-a-chip and its application in hepatotoxicity screening
点击查看 >>
Author：
Yi-bo Zheng, Li-dong Ma, Jian-lin Wu, Yi-ming Wang, Xian-sheng Meng, Ping Hu, Qiong-lin Liang, Yuan-yuan Xie, Guo-an Luo
IF：
6.5560
Publish_to：
TALANTA
PMID：
35144112
Efficient Treatment of Rheumatoid Arthritis by Degradable LPCE Nano-Conjugate-Delivered p65 siRNA
点击查看 >>
Author：
Xiaohua Chen, Bailing Zhou, Yan Gao, Kaiyu Wang, Jieping Wu, Ming Shuai, Ke Men, Xingmei Duan
IF：
6.5250
Publish_to：
Pharmaceutics
PMID：
35057057
Discovery of a cinnamyl piperidine derivative as new neddylation inhibitor for gastric cancer treatment
点击查看 >>
Author：
Bo Wang, Qiu-Hua Zhang, Xiao-Jing Li, Sai-Qi Wang, Xiao-Bing Chen, Bin Yu, Hong-Min Liu
IF：
6.5140
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
34624825
Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology
点击查看 >>
Author：
Zhang Yao, Lv Wenhao, Li Hui, Dong Tiantian, Wu Hao, Su Chunhong, Shu Hong, Nie Fang
IF：
6.4290
Publish_to：
Cancer Cell International
PMID：
36154921
Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein
点击查看 >>
Author：
Shunli Yang, Xinming Zhang, Yuying Cao, Shuo Li, Junjun Shao, Shiqi Sun, Huichen Guo, Shuanghui Yin
IF：
6.4190
Publish_to：
DRUG DELIVERY
PMID：
34006158
Synthesis of Au@MOF core–shell hybrids for enhanced photodynamic/photothermal therapy
点击查看 >>
Author：
Xue Cai, Yuewu Zhao, Li Wang, Mingchao Hu, Zeen Wu, Lifen Liu, Weipei Zhu, Renjun Pei
IF：
6.3310
Publish_to：
Journal of Materials Chemistry B
PMID：
34369551
Phytosphingosine inhibits cell proliferation by damaging DNA in human cell lines
点击查看 >>
Author：
Sun C; Chang X; MacIsaac HJ; Wen J; Zhao L; Dai Z;
IF：
6.2330
Publish_to：
Ecotoxicol Environ Saf
PMID：
37001191
Neuroprotection of Kaji-Ichigoside F1 via the BDNF/Akt/mTOR Signaling Pathways against NMDA-Induced Neurotoxicity
点击查看 >>
Author：
Faju Chen, Li Wang, Fengli Jin, Liangqun Li, Tao Wang, Ming Gao, Lilang Li, Yu Wang, Zhongsheng Lou, Juan Yang, Qiji Li, Xiaosheng Yang
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36555790
Microplastic exposure induces HSP90α secretion and aggravates asthmatic airway remodeling via PI3K-Akt-mTOR pathway
点击查看 >>
Author：
Mingming Xu, Jiyuan Chen, Lin Gao, Shaoxi Cai, Hangming Dong
IF：
6.2000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
39923560
Omaveloxolone ameliorates cognitive dysfunction in APP/PS1 mice by stabilizing the STAT3 pathway
点击查看 >>
Author：
Xiaolin Cui, Shuai Zong, Wenao Song, Cuicui Wang, Yingchao Liu, Li Zhang, Pengcheng Xia, Xueying Wang, Hao Zhao, Le Wang, Zhiming Lu
IF：
6.1000
Publish_to：
LIFE SCIENCES
PMID：
37951537
Global Phosphoproteomics Analysis of IBRS-2 Cells Infected With Senecavirus A
点击查看 >>
Author：
Li Jieyi, Zhang Zhongwang, Lv Jianliang, Ma Zhongyuan, Pan Li, Zhang Yongguang
IF：
6.0640
Publish_to：
Frontiers in Microbiology
PMID：
35154063
Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis
点击查看 >>
Author：
Xingyao Pei, Haiyang Jiang, Xinyu Liu, Liuan Li, Cun Li, Xilong Xiao, Daowen Li, Shusheng Tang
IF：
6.0250
Publish_to：
FOOD AND CHEMICAL TOXICOLOGY
PMID：
33762183
Ferrostatin-1 ameliorates Cis-dichlorodiammineplatinum(II)-induced ovarian toxicity by inhibiting ferroptosis
点击查看 >>
Author：
Zhang Lu, Dong Zhe, Jiang Fan, Huang Huaju, Ding Hui, Liu Meimei
IF：
6.0000
Publish_to：
MOLECULAR MEDICINE
PMID：
39272008
Construction of reduction-sensitive heterodimer prodrugs of doxorubicin and dihydroartemisinin self-assembled nanoparticles with antitumor activity
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Author：
Guolian Ren, Danyu Duan, Geng Wang, Rongrong Wang, Yujie Li, Hengtong Zuo, Qichao Zhang, Guoshun Zhang, Yongdan Zhao, Ruili Wang, Shuqiu Zhang
IF：
5.9990
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
PMID：
35700564
PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling.
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Author：
Yan-Jun Cao, Jing-Yan Li, Pan-Xia Wang, Zhi-Rong Lin, Wen-Jing Yu, Ji-Guo Zhang, Jing Lu, Pei-Qing Liu
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
35237161
Cell penetrating peptide TAT-functionalized liposomes for efficient ophthalmic delivery of flurbiprofen: Penetration and its underlying mechanism, retention, anti-inflammation and biocompatibility
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Author：
Baohuan Wu, Mengshun Li, Keke Li, Wei Hong, Qingzhi Lv, Youjie Li, Shuyang Xie, Jingtian Han, Baocheng Tian
IF：
5.8750
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
33647409
Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Protect Against Cerebral Ischemia/Reperfusion Injury by Attenuating Oxidative Stress and Apoptosis via the Silent Information Regulator 1 Signaling Pathway
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Author：
Fangma Yijia, Zhou Huifen, Shao Chongyu, Yu Li, Yang Jiehong, Wan Haitong, He Yu
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
34658877
Coaxial electrostatic spray-based preparation of localization missile liposomes on a microfluidic chip for targeted treatment of triple-negative breast cancer
点击查看 >>
Author：
Qian Wang, Wenjie Xu, Qi Li, Chunpeng He, Yang Liu, Jia Liu, Rongrong Wang, Junyong Wu, Daxiong Xiang, Chuanpin Chen
IF：
5.8000
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
37437856
Deletion of SIRT6 in vascular smooth muscle cells facilitates vascular calcification via suppression of DNA damage repair
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Author：
Siyi Wang, Li Li, Qingchun Liang, Yuanzhi Ye, Zirong Lan, Qianqian Dong, An Chen, Mingwei Fu, Yining Li, Xiaoyu Liu, Jing-Song Ou, Lihe Lu, Jianyun Yan
IF：
5.7630
Publish_to：
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
PMID：
36367517
Solasonine Causes Redox Imbalance and Mitochondrial Oxidative Stress of Ferroptosis in Lung Adenocarcinoma
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Author：
Yao-Ying Zeng, Ying-Bin Luo, Xu-Dong Ju, Bo Zhang, Ya-Jing Cui, Yan-Bin Pan, Jian-Hui Tian, Wen-Jing Teng, Jianchun Wu, Yan Li
IF：
5.7380
Publish_to：
Frontiers in Oncology
PMID：
35664792
RGD Peptide Modified Erythrocyte Membrane/Porous Nanoparticles Loading Mir-137 for NIR-Stimulated Theranostics of Glioblastomas
点击查看 >>
Author：
Minghui Li, Xinyu Cui, Feng Wei, Chao Li, Xiaojun Han
IF：
5.7190
Publish_to：
Nanomaterials
PMID：
35564173
Protein Precoating with Concentration-Dependent Manner Breaks through the Biomacromolecular Barrier of Transferrin-Functionalized Nanoparticle in Intestinal Mucosa
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Author：
Dan Yang, Yao Zhou, Mengqi Wang, Ying Yuan, Yuqi Feng, Yapeng Fang, Guoliang Li, Dechun Liu, Xiaolin Yao
IF：
5.7000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
39918287
LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p
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Author：
Li Shichao, Zhang Lingyan, Lin Jiajie, Su Achou, Liu Xiyun, Zhang Jingge, Xian Xiaohui, Hu Yuyan, Li Wenbin, Sun Shaoguang, Zhang Min
IF：
5.6820
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
35451738
B-cell receptor associated protein 31 deficiency decreases the expression of adhesion molecule CD11b/CD18 and PSGL-1 in neutrophils to ameliorate acute lung injury
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Author：
Guo-xun Li, Xiao-han Jiang, Jing-nan Zang, Ben-zhi Zhu, Cong-cong Jia, Kun-wei Niu, Xia Liu, Rui Jiang, Bing Wang
IF：
5.6520
Publish_to：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
PMID：
36210579
Perillaldehyde ameliorates lipopolysaccharide-induced acute lung injury via suppressing the cGAS/STING signaling pathway
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Author：
Jiahui Wei, Zhengjia Liu, Hongbin Sun, Lei Xu
IF：
5.6000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
38368770
Structure and Anti-Inflammation Potential of Lipoteichoic Acids Isolated from Lactobacillus Strains
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Author：
Qianqian Lu, Yingqi Guo, Guo Yang, Lei Cui, Zhen Wu, Xiaoqun Zeng, Daodong Pan, Zhendong Cai
IF：
5.5610
Publish_to：
Foods
PMID：
35681360
Cell-Penetrating Peptide Modified PEG-PLA Micelles for Efficient PTX Delivery
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Author：
Shuai Q; Cai Y; Zhao G; Sun X
IF：
5.5420
Publish_to：
Int J Mol Sci
PMID：
32182734
EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis
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Author：
Mingchao Jin, Xiaohu Wu, Jin Hu, Yijie Chen, Bingsheng Yang, Chubin Cheng, Mankai Yang, Xianrong Zhang
IF：
5.5000
Publish_to：
PLoS Pathogens
PMID：
39102432
Shrimp Plasma MANF Works as an Invertebrate Anti-Inflammatory Factor via a Conserved Receptor Tyrosine Phosphatase
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Author：
Luo Kaiwen, Chen Yaohui, Wang Fan
IF：
5.4260
Publish_to：
JOURNAL OF IMMUNOLOGY
PMID：
35149533
An inorganic-organic-polymeric nanovehicle for targeting delivery of doxorubicin: Rational assembly, pH-stimulus release, and dual hyperthermia/chemotherapy of hepatocellular carcinoma
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Author：
Jianying Yang, Zhao Wang, Chunhong Mo, Haikun Luo, Shuting Li, Qian Mo, You Qin, Fan Yang, Xinchun Li
IF：
5.4000
Publish_to：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
PMID：
36871489
Inhibitory effects of Panax ginseng glycoproteins in models of doxorubicin-induced cardiac toxicity in vivo and in vitro
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Author：
Yajun Chen, Lei Wang, Tianjia Liu, Zhidong Qiu, Ye Qiu, Da Liu
IF：
5.3960
Publish_to：
Food & Function
PMID：
34617939
Microfluidic Formulation of Curcumin-Loaded Multiresponsive Gelatin Nanoparticles for Anticancer Therapy
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Author：
Yu Xia, Ruicheng Xu, Siyuan Ye, Jiaxuan Yan, Piyush Kumar, Peng Zhang, Xiubo Zhao
IF：
5.3950
Publish_to：
ACS Biomaterials Science & Engineering
PMID：
37140447
Activity and Tissue Distribution of Antisense Oligonucleotide CT102 Encapsulated with Cytidinyl/Cationic Lipid against Hepatocellular Carcinoma
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Author：
Jing Guan, Yufei Pan, Huantong Li, Yuejie Zhu, Yujing Gao, Jie Wang, Ying Zhou, Zhu Guan, Zhenjun Yang
IF：
5.3640
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
35508302
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis
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Author：
Fangming Dong, Linlin Qu, Zhiguang Duan, Ying He, Xiaoxuan Ma, Daidi Fan
IF：
5.3070
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
37043883
Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway
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Author：
Rong Wang, Yihan Hou, Guojun Geng, Xiaolei Zhu, Zhilin Wang, Weifeng Cai, Juanping Ye, Senxia Zhao, Yanjun Mi, Jie Jiang
IF：
5.3000
Publish_to：
American Journal of Cancer Research
PMID：
36895968
Enhanced Neuroprotective Effects of Epicatechin Gallate Encapsulated by Bovine Milk-Derived Exosomes against Parkinson’s Disease through Antiapoptosis and Antimitophagy
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Author：
Siqi Luo, Xiuli Sun, Meng Huang, Qianhui Ma, Libo Du, Yan Cui
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
33890462
Maleimide-functionalized phospholipid/Pluronic F127 mixed micelles for efficient ophthalmic delivery of voriconazole against Candida albicans
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Author：
Baohuan Wu, Sixiang Sai, Keke Li, Xingchen Sun, Jingtian Han, Baocheng Tian
IF：
5.2680
Publish_to：
COLLOIDS AND SURFACES B-BIOINTERFACES
PMID：
34775252
Cloperastine inhibits esophageal squamous cell carcinoma proliferation in vivo and in vitro by suppressing mitochondrial oxidative phosphorylation
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Author：
Li Bo, Yu Yin, Jiang Yanan, Zhao Lili, Li Ang, Li Mingzhu, Yuan Baoyin, Lu Jing, Dong Ziming, Zhao Jimin, Liu Kangdong
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
34226508
Plantaricin BM-1 decreases viability of SW480 human colorectal cancer cells by inducing caspase-dependent apoptosis
点击查看 >>
Author：
He Wang, Junhua Jin, Xiaona Pang, Zheng Bian, Jingxin Zhu, Yanling Hao, Hongxing Zhang, Yuanhong Xie
IF：
5.2000
Publish_to：
Frontiers in Microbiology
PMID：
36687624
Orexin-A alleviates astrocytic apoptosis and inflammation via inhibiting OX1R-mediated NF-κB and MAPK signaling pathways in cerebral ischemia/reperfusion injury
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Author：
Dandan Xu, Tingting Kong, Ziqi Shao, Minghui Liu, Rumin Zhang, Shengnan Zhang, Qingxia Kong, Jing Chen, Baohua Cheng, Chunmei Wang
IF：
5.1870
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
34358627
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis
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Author：
Yan Zhou, Lu-Lu Wen, Yan-Fei Li, Kai-Min Wu, Ran-Ran Duan, Yao-Bing Yao, Li-Jun Jing, Zhe Gong, Jun-Fang Teng, Yan-Jie Jia
IF：
5.1350
Publish_to：
Neural Regeneration Research
PMID：
34100456
Gastroprotective 2-(2-phenylethyl)chromone-sesquiterpene hybrids from the resinous wood of Aquilaria sinensis (Lour.) Gilg
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Author：
Hang Zhang, Jia-Le Ma, Chuang Chang, He Ta, Yun-Fang Zhao, She-Po Shi, Yue-Lin Song, Peng-Fei Tu, Hui-Xia Huo, Jiao Zheng, Jun Li
IF：
5.1000
Publish_to：
BIOORGANIC CHEMISTRY
PMID：
36758274
Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy-mediated degradation of damaged mitochondria
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Author：
Xiaozhou Wang， Hongyan Li， Jie Wang， Huiling Xu， Kun Xue， Xiaoting Liu， Zhizhong Zhang， Jianzhu Liu， Yongxia Liu
IF：
5.0700
Publish_to：
MICROBIOLOGICAL RESEARCH
PMID：
37267814
Substantially Improved Electrofusion Efficiency of Hybridoma Cells: Based on the Combination of Nanosecond and Microsecond Pulses
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Author：
Meng Wu, Qiang Ke, Jinhao Bi, Xinhao Li, Shuheng Huang, Zuohua Liu, Liangpeng Ge
IF：
5.0460
Publish_to：
Bioengineering-Basel
PMID：
36134996
MYOD1 inhibits avian adipocyte differentiation via miRNA-206/KLF4 axis
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Author：
Wang Zheng, Zhao Qiangsen, Li Xiaoqin, Yin Zhongtao, Chen Sirui, Wu Sen, Yang Ning, Hou Zhuocheng
IF：
5.0320
Publish_to：
Journal of Animal Science and Biotechnology
PMID：
33952351
Nanoreactor activated in situ for starvation-chemodynamic therapy of breast cancer
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Author：
Linyu Gao, Xiangyang Xuan, Mingli Sui, Jingjing Wang, Yaping Wang, Huijuan Zhang
IF：
5.0160
Publish_to：
JOURNAL OF DRUG TARGETING
PMID：
35379059
Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways
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Author：
Haijin Liu, Jianxia Tian, Kejia Lu, Yangyang Li, Zhao Guan, Xuhong Cao, Xiaoqin Li, Zhengwu Chang, Xinglong Wang, Xiao Sa, Zengqi Yang
IF：
5.0050
Publish_to：
Transboundary and Emerging Diseases
PMID：
34904395
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence
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Author：
Xiuxian Wei, Yi Li, Tao Jiang, Pengcheng Luo, Yue Dai, Qian Wang, Mulin Xu, Jinhua Yan, Yongjun Li, Jingwen Gao, Lei Liu, Cuntai Zhang, Yu Liu
IF：
5.0000
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
38331337
Nardoguaianone L Isolated from Nardostachys jatamansi Improved the Effect of Gemcitabine Chemotherapy via Regulating AGE Signaling Pathway in SW1990 Cells
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Author：
Yi-Dan Zheng, Li-Mei Ma, Jin-Jian Lu, Tian Chai, Mohammad Reza Naghavi, Jun-Yi Ma, Chun-Yan Sang, Jun-Li Yang
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36296442
Effect of unsoluble corrosion products of WE43 alloys in vitro on macrophages
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Author：
Li Dong, Zhiyuan Shen, Huidi Zhang, Binmei Zhang, Yinze Zhou, Xin Lv, Xiaojian Hong, Jiaren Liu, Wei Yang
IF：
4.9000
Publish_to：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
PMID：
37681297
Docosahexaenoic acid (DHA) promotes recovery from postoperative ileus and the repair of the injured intestinal barrier through mast cell-nerve crosstalk
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Author：
Keqian Yi, Liya An, Yuxing Qi, Ting Yang, Yongqing Duan, Xiaohu Zhao, Pengcheng Zhang, Xingzong Huang, Xianming Su, Zhiyi Tang, Dali Sun
IF：
4.8000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
38823183
ROS-induced moderate autophagy of haemocytes confers resistance of Mercenaria mercenaria to air exposure stress
点击查看 >>
Author：
Cong Zhou, Yan Zou, Zhi Hu, Mei-jie Yang, Pu Shi, Yong-ren Li, Yong-jun Guo, Tao Zhang, Hao Song
IF：
4.7000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
37722439
Identification and functional characterization of an immune adapter molecular TRIF in Northeast Chinese lamprey (Lethenteron morii)
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Author：
Ze-Bin Zhou, Meng-Jie Zhang, Yuan-Yuan He, Shi-Cheng Bao, Xiang-Yang Zhang, Weiming Li, Qing-Hua Zhang
IF：
4.6220
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
35452833
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT
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Author：
Hao Wu, Wen-hao Lv, Yang-yang Zhu, Ying-ying Jia, Fang Nie
IF：
4.6000
Publish_to：
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
PMID：
36621614
Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis
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Author：
Yinzi Xin, Wei Wang, Enyu Mao, Hefeng Yang, Song Li
IF：
4.5290
Publish_to：
MEDIATORS OF INFLAMMATION
PMID：
36466156
Platelet Membrane-Camouflaged Silver Metal–Organic Framework Biomimetic Nanoparticles for the Treatment of Triple-Negative Breast Cancer
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Author：
Haiting Liu, Guangqing Cai, Shuai Yuan, Xionghui Zhou, Rong Gui, Rong Huang
IF：
4.5000
Publish_to：
MOLECULAR PHARMACEUTICS
PMID：
38857525
Oxidized phospholipid POVPC contributes to vascular calcification by triggering ferroptosis of vascular smooth muscle cells
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Author：
Lihe Lu, Yuanzhi Ye, Yajun Chen, Liyun Feng, Jiali Huang, Qingchun Liang, Zirong Lan, Qianqian Dong, Xiaoyu Liu, Yining Li, Xiuli Zhang, Jing-Song Ou, An Chen, Jianyun Yan
IF：
4.4000
Publish_to：
FASEB JOURNAL
PMID：
38581243
Synthesis, crystal structures, anticancer activities and molecular docking studies of novel thiazolidinone Cu(II) and Fe(III) complexes targeting lysosomes: special emphasis on their binding to DNA/BSA
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Author：
Jia Shao, Qiang Zhang, Jing Wei, Zhiguang Yuchi, Peng Cao, Shao-Qing Li, Shan Wang, Jing-Yuan Xu, Shuang Yang, Yi Zhang, Jin-Xia Wei, Jin-Lei Tian
IF：
4.3900
Publish_to：
DALTON TRANSACTIONS
PMID：
34473154
Transcriptomic study of the mechanism by which the Kai Yu Zhong Yu recipe improves oocyte quality in a stressed mouse model
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Author：
Xiaoli Zhao, Ruihong Ma, Xiaoyu Zhang, Baojuan Wang, Beilei Rong, Nan Jiang, Weihua Feng, Mingli Chen, Zhipeng Huo, Shuming Li, Tian Xia
IF：
4.3600
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
34090913
Thalidomide-based Pt(IV) prodrugs designed to exert synergistic effect of immunomodulation and chemotherapy
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Author：
Zhe Li, Xiao-Jing Ding, Xin Qiao, Xiao-Meng Liu, Xin Qiao, Cheng-Zhi Xie, Rui-Ping Liu, Jing-Yuan Xu
IF：
4.3360
Publish_to：
JOURNAL OF INORGANIC BIOCHEMISTRY
PMID：
35472743
Nitroreductase-responsive photosensitizers for selective imaging and photo-inactivation of intracellular bacteria
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Author：
Wanpeng Zhou, Xuwen Da, Yao Jian, Yatong Peng, Xiulian Liu, Yunli Xu, Yao Wu, Xuesong Wang, Qianxiong Zhou
IF：
4.3000
Publish_to：
CHEMISTRY-A EUROPEAN JOURNAL
PMID：
38233363
Dedifferentiation of Human Adipocytes After Fat Transplantation
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Author：
Chai Yimeng, Chen Yuanjing, Yin Bo, Zhang Xinyu, Han Xuefeng, Cai Lei, Yin Ningbei, Li Facheng
IF：
4.2830
Publish_to：
Aesthetic Surgery Journal
PMID：
35032169
HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model
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Author：
Dan Li, Xian Xie, Zishun Zhan, Nannan Li, Ni Yin, Shikun Yang, Jishi Liu, Jianwen Wang, Zhi Li, Bin Yi, Hao Zhang, Wei Zhang
IF：
4.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
38871033
The Roles of Different Multigene Combinations of Pdx1, Ngn3, Sox9, Pax4, and Nkx2.2 in the Reprogramming of Canine ADSCs Into IPCs
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Author：
Dengke Gao, Pengxiu Dai, Zhixin Fan, Jinglu Wang, Yihua Zhang
IF：
4.1390
Publish_to：
CELL TRANSPLANTATION
PMID：
35236160
Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus
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Author：
Shen D; Lu Y; Li G; Hu M; Li S; Ju H; Zhang M; Wan
IF：
4.1320
Publish_to：
Cell Signal
PMID：
34634453
Human umbilical cord mesenchymal stem cell-derived exosomal microRNA-148a-3p inhibits neointimal hyperplasia by targeting Serpine1
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Author：
Xiaoyu Zhang, Yu Zhou, Yanchen Ye, Ridong Wu, Wen Li, Chen Yao, Shenming Wang
IF：
4.1140
Publish_to：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
PMID：
35218720
Smart delivery of poly-peptide composite for effective cancer therapy
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Author：
Xin Yuan, Yingzhou Qin, Qingmei Tian, Cuijuan Liu, Xiangzhou Meng, Bo Qie, Fan Gao, Ying Huang, Guanghui Xu, Guang Yang, Yimin Zhu
IF：
4.1030
Publish_to：
Biomedical Materials
PMID：
34996052
Adverse effects of knocking down chitin synthase A on female reproduction in Culex pipiens pallens (Diptera: Culicidae)
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Author：
Huan Wang, Xiaoshan Yang, Jin Liu, Jingwei Xu, Ruimin Zhang, Junnan Zheng, Bo Shen, Yan Sun, Dan Zhou
IF：
4.1000
Publish_to：
PEST MANAGEMENT SCIENCE
PMID：
37409377
Real-time drug release monitoring from pH-responsive CuS-encapsulated metal–organic frameworks
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Author：
Bei Liu, Lirong Sun, Xijian Lu, Yuping Yang, Hongshang Peng, Zhaogang Sun, Juan Xu, Hongqian Chu
IF：
4.0360
Publish_to：
RSC Advances
PMID：
35425048
Tanshinone analogue inhibits castration-resistant prostate cancer cell growth by inhibiting glycolysis in an AR-dependent manner
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Author：
Jia Yu, Shengyou Li, Sha Cheng, Mashaal Ahmad, Chao Chen, Xinwei Wan, Shinan Wei, Weidong Pan, Heng Luo
IF：
4.0000
Publish_to：
JOURNAL OF BIOLOGICAL CHEMISTRY
PMID：
38447792
Polychlorinated Biphenyl Quinone Metabolites Cause Neutrophil Extracellular Traps in Mouse Bone Marrow Neutrophils
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Author：
Lu Peng, Xiangyu Zhu, Zongming Qin, Jing Liu, Erqun Song, Yang Song
IF：
3.9730
Publish_to：
CHEMICAL RESEARCH IN TOXICOLOGY
PMID：
35168318
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia
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Author：
Jiazheng Cai, Jing Liu, Jing Yan, Xuexia Lu, Xiaoli Wang, Si Li, Kamal Mustafa, Huihui Wang, Ying Xue, Manal Mustafa, Alpdogan Kantarci, Zhe Xing
IF：
3.9460
Publish_to：
JOURNAL OF PERIODONTAL RESEARCH
PMID：
35944267
Phospho-EGFRTyr992 is synergistically repressed by co-inhibition of histone deacetylase (HDAC) and phosphatidylinositol 3-kinase (PI3K), which attenuates resistance to erlotinib in head and neck cancer cells
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Author：
Xuejun Chen, Wen Gao, Gaofei Yin, Wei Guo, Junwei Huang, Zhigang Huang, Yang Zhang
IF：
3.9320
Publish_to：
Annals of Translational Medicine
PMID：
34734007
A nuclear receptor heterodimer, CgPPAR2-CgRXR, acts as a regulator of carotenoid metabolism in Crassostrea gigas
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Author：
Sai Wan, Qi Li, Hong Yu, Shikai Liu, Lingfeng Kong
IF：
3.9130
Publish_to：
GENE
PMID：
35390448
Growth differentiation factor-15 promotes immune escape of ovarian cancer via targeting CD44 in dendritic cells
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Author：
Yunge Gao, Ying Xu, Shuhui Zhao, Luomeng Qian, Tingting Song, Jiao Zheng, Jianfang Zhang, Biliang Chen
IF：
3.9050
Publish_to：
EXPERIMENTAL CELL RESEARCH
PMID：
33771482
In Vivo and In Vitro Interactions between Exopolysaccharides from Bacillus thuringensis HD270 and Vip3Aa11 Protein
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Author：
Tianjiao Ma, Jinqiu Huang, Pengdan Xu, Changlong Shu, Zeyu Wang, Lili Geng, Jie Zhang
IF：
3.9000
Publish_to：
Toxins
PMID：
38787067
Sesquiterpene coumarins from Ferula sinkiangensis and their anti-pancreatic cancer effects
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Author：
Jia-Lin Wang, Chun-Yan Sang, Jun Wang, Pei-Lin Li, Tian Chai, Mohammad Reza Naghavi, Ya-Min Zhao, Jun-Li Yang
IF：
3.8000
Publish_to：
PHYTOCHEMISTRY
PMID：
37597719
The protective effect of puerarin-loaded mesoporous silicon nanoparticles on alcoholic hepatitis through mTOR-mediated autophagy pathway
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Author：
Zhang Xia-xia, Lang Yan-fei, Li Xin, Li Zheng, Xu You-qing, Chu Hong-qian
IF：
3.7830
Publish_to：
BIOMEDICAL MICRODEVICES
PMID：
36308627
High-content screening of active components of Traditional Chinese Medicine inhibiting TGF-β-induced cell EMT
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Author：
Mengzhen Xu, Qinghua Cui, Wen Su, Dan Zhang, Jiaxu Pan, Xiangqi Liu, Zheng Pang, Qingjun Zhu
IF：
3.7760
Publish_to：
Heliyon
PMID：
36042745
The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration
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Author：
Chen WJ; Xie J; Lin X; Ou MH; Zhou J; Wei XL; Chen
IF：
3.7610
Publish_to：
J Endod
PMID：
33775732
ITGA5 inhibition in pancreatic stellate cells re-educates the in vitro tumor-stromal crosstalk
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Author：
Wang Tao, Yang Jian, Mao Juanli, Zhu Lizhi, Luo Xiu, Cheng Chao, Zhang Lu
IF：
3.7380
Publish_to：
MEDICAL ONCOLOGY
PMID：
36469173
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS
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Author：
Dianyu Li, Rongqian Mo, Xiaoyi Li, Rongrong Cheng, Jingying Xie, Hongshan Li, Yanmei Yang, Shasha Li, Huixia Li, Zhenfang Yan, Suocheng Wei, Adi Idris, Xiangrong Li, Ruofei Feng
IF：
3.7000
Publish_to：
mSphere
PMID：
38757961
Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells
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Author：
Shanshan Zhao, Qixue Bao, Guochen Ma, Yuqin Yao, Linshen Xie, Jingyuan Xiong
IF：
3.6850
Publish_to：
TOXICOLOGY IN VITRO
PMID：
36410618
Effects of quercetin on apoptosis and extracellular matrix degradation of chondrocytes induced by oxidative stress-mediated pyroptosis
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Author：
Qing Wang, Lujing Ying, Bing Wei, Yikui Ji, Yi Xu
IF：
3.6520
Publish_to：
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
PMID：
34791735
Scavenger receptor B1 mediates phagocytosis and the antimicrobial peptide pathway in the endoparasitic wasp Micropilits mediator
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Author：
Li-Zhen Zhou, Rui-Juan Wang, You-Ying Yan, Shuocheng Zeng, Zhen Zou, Zhiqiang Lu
IF：
3.6360
Publish_to：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
PMID：
33549640
Fusion protein and hemagglutinin of canine distemper virus co-induce apoptosis in canine mammary tumor cells
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Author：
Gu Chenchen, Su Jun, Wang Jigui, Xie Qianqian, Wu Jing, Xiao Jun, Liu Weiquan
IF：
3.6000
Publish_to：
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
PMID：
37249647
Changes in the mechanical properties of human mesenchymal stem cells during differentiation
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Author：
Fei He, Chendong Yang, Haoye Liu, Jizeng Wang
IF：
3.5000
Publish_to：
Royal Society Open Science
PMID：
36636310
β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows
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Author：
Zhihao Dong, Xudong Sun, Yan Tang, Shengbin Luo, Hongdou Jia, Qiushi Xu, Qianming Jiang, Juan J. Loor, Wei Xu, Chuang Xu
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
36105004
Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo
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Author：
Tian Luo, Zhao Li, Xue-Mei Deng, Kan Jiang, Dan Liu, Hong-Hua Zhang, Tao Shi, Lin-Yi Liu, Huai-Xiu Wen, Qi-En Li, Zhen Wang
IF：
3.4610
Publish_to：
BIOORGANIC & MEDICINAL CHEMISTRY
PMID：
35286954
Exploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation
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Author：
Yang Y; Yang Y; Shen Y; Liu J; Zeng Y; Wei C; Liu
IF：
3.4560
Publish_to：
Pharm Biol
PMID：
36656546
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis
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Author：
Jinna Xie, Zehua Ye, Lei Li, Yuqi Xia, Run Yuan, Yuan Ruan, Xiangjun Zhou
IF：
3.4230
Publish_to：
Molecular Medicine Reports
PMID：
35703358
IGF 1 inhibits palmitic acid induced mitochondrial apoptosis in macrophages
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Author：
Wanying Tang, Ming Zhang, Yu Wang, Dan Ma, Mi Hu, Yangkai Zhang, Huiling Lin, Weiwei Jiang, Yuxin Ouyang, Liping Jiang, Pingping He, Guojun Zhao, Xinping Ouyang
IF：
3.4000
Publish_to：
Molecular Medicine Reports
PMID：
37921069
TBHQ alleviates pyroptosis and necroptosis in chicken alveolar epithelial cells induced by fine particulate matter from broiler houses
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Author：
Mengxue Xi, Dan Shen, Pengyuan Dai, Guofeng Han, Chunmei Li
IF：
3.3520
Publish_to：
POULTRY SCIENCE
PMID：
34963088
Effects of Photodynamic Therapy Using Red LED-light Combined with Hypocrellin B on Apoptotic Signaling in Cutaneous Squamous Cell Carcinoma A431 cells
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Author：
Yuanyuan Liu, Zhiqiang Cao, Guo Wei
IF：
3.3000
Publish_to：
Photodiagnosis and Photodynamic Therapy
PMID：
37390854
Luteolin Isolated from Polygonum cuspidatum Is a Potential Compound against Nasopharyngeal Carcinoma
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Author：
Yu Xiong, Wenliang Zhong, Jie Liu, Bo Cheng, Jingying Fan, Fangliang Zhou, Lan He, Daofa Tian, Yingchun He
IF：
3.2460
Publish_to：
Biomed Research International
PMID：
36588531
Characteristics and Expression of circ_003628 and Its Promoted Effect on Proliferation and Differentiation of Skeletal Muscle Satellite Cells in Goats
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Author：
Huimin Zhen, Jiyuan Shen, Jiqing Wang, Yuzhu Luo, Jiang Hu, Xiu Liu, Shaobin Li, Zhiyun Hao, Mingna Li, Bingang Shi, Yuanhua Gu
IF：
3.2310
Publish_to：
Animals
PMID：
36230263
Activation of autophagy promotes the inhibitory effect of curcumin analog EF-24 against MDA-MB-231 cancer cells
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Author：
Yin-Yin Zhao, Jun Li, Hao-Qi Wang, Hao-Bo Zheng, Shi-Wei Ma, Guang-Zhou Zhou
IF：
3.2000
Publish_to：
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
PMID：
38348710
Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury
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Author：
Zi-Qi Shao, Shan-Shan Dou, Jun-Ge Zhu, Hui-Qing Wang, Chun-Mei Wang, Bao-Hua Cheng, Bo Bai
IF：
3.1710
Publish_to：
Neural Regeneration Research
PMID：
33269749
SKF38393 prevents high glucose (HG)-induced endothelial dysfunction by inhibiting the effects of HG on cystathionine γ-lyase/hydrogen sulfide activity and via a RhoA/ROCK1 pathway
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Author：
Gui-Quan Chang, Shu-Zhi Bai, Feng-Qi Sun, Ren Wu, Can Wei, Xin Wen, Yu-Xin Xi, Jing-Hui Hao, Altaany Zaid, Hong-Zhu Li
IF：
3.1150
Publish_to：
Frontiers in Bioscience-Landmark
PMID：
35226992
Sequence-dependent effects of hematoporphyrin derivatives (HPD) photodynamic therapy and cisplatin on lung adenocarcinoma cells
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Author：
Nana Li, Shichao Cui, Aizhen Yang, Baohong Xiao, Yiwei Cao, Xiaohui Yang, Cunzhi Lin
IF：
3.1000
Publish_to：
Photodiagnosis and Photodynamic Therapy
PMID：
38679153
The protective mechanism of human umbilical cord mesenchymal stem cell-derived exosomes against neutrophil extracellular trap-induced placental damage
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Author：
Yuan Wang, Qingfeng Lv, Jing Li, Min Hu, Hao Li, Meihua Zhang, Di Shen, Xietong Wang
IF：
3.0000
Publish_to：
PLACENTA
PMID：
38823320
A novel Schiff base cobalt(III) complex induces a synergistic effect on cervical cancer cells by arresting early apoptosis stage
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Author：
Liao Wen-Hui, Song Xue-Qing, Kong Yan-Jie, Bao Rui-Dan, Li Fang-Fang, Zhou Jie, Zhao Qi-Hua, Xu Jing-Yuan, Xie Ni, Xie Ming-Jin
IF：
2.9490
Publish_to：
BIOMETALS
PMID：
33389333
Benzo[b]fluoranthene damages coronary artery and affects atherosclerosis markers in mice and umbilical vein endothelial cells
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Author：
Hang Luo, Shanshan Zhao, Jing Zi, Yifan Hu, Yuqin Yao, Jingyuan Xiong
IF：
2.9000
Publish_to：
TOXICOLOGY LETTERS
PMID：
39395681
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway
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Author：
Wenqian Hu, Hongjiao Wu, Ang Li, Xuan Zheng, Wenli Zhang, Qinqin Tian, Xuemei Zhang
IF：
2.7510
Publish_to：
Experimental and Therapeutic Medicine
PMID：
36382103
Cordycepin enhances hyperthermia-induced apoptosis and cell cycle arrest by modulating the MAPK pathway in human lymphoma U937 cells
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Author：
Shi Liying, Cao He, Fu Siyu, Jia Zixian, Lu Xuan, Cui Zhengguo, Yu Dayong
IF：
2.7420
Publish_to：
MOLECULAR BIOLOGY REPORTS
PMID：
35763180
Baicalin enhances the thermotolerance of mouse blastocysts by activating the ERK1/2 signaling pathway and preventing mitochondrial dysfunction
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Author：
Huatao Li, Xia Cong, Junxia Sui, Zhongling Jiang, Kaiqiang Fu, Yanjun Huan, Rongfeng Cao, Wenru Tian, Yanni Feng
IF：
2.7400
Publish_to：
THERIOGENOLOGY
PMID：
34808561
Phenylbutyric acid inhibits hypoxia-induced trophoblast apoptosis and autophagy in preeclampsia via the PERK/ATF-4/CHOP pathway
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Author：
Yinfeng Li, Yongjie Guo, Dan Wu, Ling Ai, Rongrong Wu, Zepeng Ping, Kangyuan Zhu
IF：
2.7000
Publish_to：
MOLECULAR REPRODUCTION AND DEVELOPMENT
PMID：
38644727
Astaxanthin Prevents Tuberculosis-Associated Inflammatory Injury by Inhibiting the Caspase 4/11-Gasdermin-Pyroptosis Pathway
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Author：
Li Li, Zulipikaer Abudureheman, Xuemei Zhong, Liang Gao, Hui Gong, Chuanjiang He, Boyi Yang, Jie Ren, Ayiguli Alimu, Subinuer Yilamujiang, Fan Yang, Xiaoguang Zou
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
36523416
Loss-of-function SLC25A20 mutation causes carnitine-acylcarnitine translocase deficiency by reducing SLC25A20 protein stability
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Author：
Zhongzhi Gan, Xiaofeng Wei, Yingchun Zheng, Qiqi Zheng, Shushu Fan, Fu Xiong
IF：
2.6000
Publish_to：
GENE
PMID：
39732347
Lappaconitine hydrochloride inhibits proliferation and induces apoptosis in human colon cancer HCT-116 cells via mitochondrial and MAPK pathway
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Author：
Na Song, Junyi Ma, Wei Hu, Yongyue Guo, Ling Hui, Mohamed Aamer, Jun Ma
IF：
2.4790
Publish_to：
ACTA HISTOCHEMICA
PMID：
34058516
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction
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Author：
Zhu X; Wang F; Lei X; Dong W
IF：
2.4200
Publish_to：
Exp Biol Med (Maywood)
PMID：
33215523
Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking
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Author：
Huiling Xu, Xiaozhou Wang, Zhizhong Zhang, Jiaqing Hu, Yongtao Yu, Jiandong Wang, Yongxia Liu, Jianzhu Liu
IF：
2.4000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
38626624
Daucosterol regulates JAK2-STAT3 signaling pathway to promote megakaryocyte differentiation
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Author：
Zhongkang Zhang, Guangbin Shang, Zhen Lu, Jia Hu, Huizhen Liu, Ting Lu, Xiaonan Lu
IF：
2.1000
Publish_to：
BLOOD CELLS MOLECULES AND DISEASES
PMID：
38796983
Fascin-1 Promotes Cell Metastasis through Epithelial–Mesenchymal Transition in Canine Mammary Tumor Cell Lines
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Author：
Xin Wang, Ye Zhou, Linhao Wang, Abdul Haseeb, Hongquan Li, Xiaozhong Zheng, Jianhua Guo, Xiaoliang Cheng, Wei Yin, Na Sun, Panpan Sun, Zhenbiao Zhang, Huizhen Yang, Kuohai Fan
IF：
2.0000
Publish_to：
Veterinary Sciences
PMID：
38921985
The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta
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Author：
Kunhua ZHENG, Longfei XIAO, Naihan YUAN, Xihui SHENG, Xiaolong QI, Yingqiu WANG, Chang CHEN, Kaijun GUO, Lin YANG, Bingying LIU, Xiangguo WANG
IF：
1.9000
Publish_to：
JOURNAL OF REPRODUCTION AND DEVELOPMENT
PMID：
39662929
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species–mediated activation of the NLRP3 inflammasome
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Author：
Yi Peng, Yue-Hui Huang, Xiao Luo, Mei-Chen Li, Qing-Qing Xiao, Lu Qiu, Qiang Fu
IF：
1.3000
Publish_to：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
PMID：
40035483
Hydrogen Sulfide Promotes Postnatal Cardiomyocyte Proliferation by Upregulating SIRT1 Signaling Pathway
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Author：
Lu Gan, Peng Cheng, Jieyun Wu, Qiyong Li, Jigang Pan, Yan Ding, Xiufeng Gao, Li Chen
IF：
1.2000
Publish_to：
International Heart Journal
PMID：
38825495
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