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产品简介
| 别名 | 制胶试剂盒 SDS-PAGE凝胶配制试剂盒 |
| 英文名称 | SDS-PAGE Gel Kit |
| 中文名称 | SDS-PAGE凝胶制备试剂盒 |
| 储存条件 | 2-8℃，avoid light，1 year |
| 规格 | 25T 50T |
| 单位 | 盒 |
| 试剂名称 | 25T | 50T | 保存条件 |
| 30%制胶液(29:1) | 100mL | 100mL×2 | 2-8℃，避光 |
| 1.5mol/LTris(pH8.8) | 100mL | 100mL×2 | 常温 |
| 1.0mol/LTris(pH6.8) | 30mL | 60mL | 常温 |
| PAGE胶凝固剂 | 1g | 2g | 干粉2-8℃；溶液-20℃ |
| 10%SDS | 5mL | 10mL | 常温 |
| PAGE胶促凝剂 | 0.8mL | 1.5mL | 2-8℃，避光 |
产品简介：
本公司生产的SDS-PAGE凝胶制备试剂盒是按照经典方法配制而成。本试剂盒提供了配制SDS-PAGE凝胶所需的各种试剂，用户只需自备制胶器具和蒸馏水，即可配制PAGE胶。本试剂盒可配制不同规格、不同聚合度的PAGE胶(即聚丙烯酰胺凝胶) 约25/50块。
注意事项：
1. PAGE胶促凝剂和10%PAGE胶凝固剂最后加，在加入前需混匀前面所加试剂。10%PAGE胶凝固剂溶液在4℃有效期为一周;PAGE胶促凝剂易挥发，使用后请盖紧瓶盖。在常温下胶30分钟内可以凝固，如温度过低，可放37℃温箱凝固。灌完分离胶后，轻轻的加1mL ddH2O封上层，胶凝固后可见到分界线。灌浓缩胶前，先倾去水层，再用吸水纸吸干。浓缩胶灌好后立刻插入梳子。浓缩胶凝固后，放入电泳液中(让电泳液漫过加样孔)，轻轻的拨出梳子，可防加样孔变形。
2. 配制量可按上表等比加减。如果所用胶浓度与上面不同，可自行调整，主要是调整30% 制胶液的量（需要浓度×总体积/30%），最后用水补足总体积。
配胶说明：
1. 先在PAGE胶凝固剂干粉中加入蒸馏水或去离子水(每克PAGE胶凝固剂需加水10mL)配置成10%溶液，将溶液分装成小体积后冻存于-20℃，制备凝胶时融化后使用。4℃保存有效期为一周。检测SDS溶液是否澄清，若出现絮状物或沉淀可放37℃片刻至溶解，不影响效果。
2. 根据目标蛋白分子量大小，选取凝胶浓度，按下表配制。先配分离胶，再配浓缩胶。
| 分离胶15% | 分离胶12% | 分离胶10% | 分离胶8% | 浓缩胶5% | |
| 总体积 | 10mL | 10mL | 10mL | 10mL | 5mL |
| 30%Acr/Bis(29:1) | 5mL | 4mL | 3.3mL | 2.7mL | 0.83mL |
| 1M Tris-HCI(PH6.8) | 0 | 0 | 0 | 0 | 0.625mL |
| 1.5M Tris-HCI(PH8.8) | 2.5mL | 2.5mL | 2.5mL | 2.5mL | 0 |
| 10%SDS | 100μL | 100μL | 100μL | 100μL | 50μL |
| 10%PAGE胶凝固剂 | 100μL | 100μL | 100μL | 100μL | 75μL |
| PAGE胶促凝剂 | 10μL | 10μL | 10μL | 10μL | 7.5μL |
| ddH20 | 2.3mL | 3.3mL | 4.0mL | 4.6mL | 3.42mL |
| 最佳分离范围 | 10-40kD | 12-60 kD | 20-80 kD | 30-90kD |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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PHYTOMEDICINE
PMID：
36343550
Synthesis of Zinc Oxide-Doped Carbon Dots for Treatment of Triple-Negative Breast Cancer
点击查看 >>
Author：
Mengqi Wang, Shuting Lan, Mingjun Song, Rongrong Zhang, Wenqi Zhang, Xiaomei Sun, Gang Liu
IF：
6.6000
Publish_to：
International Journal of Nanomedicine
PMID：
39742095
Zi Shen Decoction Inhibits Growth and Metastasis of Lung Cancer via Regulating the AKT/GSK-3β/β-Catenin Pathway
点击查看 >>
Author：
Yanxia Ma, Yu Liu, Linxin Teng, En Luo, Dekang Liu, Fuqiong Zhou, Kaiyuan Wang, Weiping Chen, Lei Bi
IF：
6.5430
Publish_to：
Oxidative Medicine and Cellular Longevity
PMID：
33777320
Design, synthesis and biological evaluation of N-anthraniloyl tryptamine derivatives as pleiotropic molecules for the therapy of malignant glioma
点击查看 >>
Author：
Xiaohong Fan, Junfang Li, Lin Long, Tao Shi, Dan Liu, Wen Tan, Honghua Zhang, Xiaoyan Wu, Xiaoyong Lei, Zhen Wang
IF：
6.5140
Publish_to：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
PMID：
34091208
Identification of digestion-resistant peptides in various processed peanut reveals their distinct allergenicity
点击查看 >>
Author：
Tianyu Hou, Jiaxi Yan, Xiaoluan Li, Li Niu, Huan Rao, Jianxiong Hao, Dandan Zhao, Xueqiang Lui, Wenhui Fu
IF：
6.5000
Publish_to：
Food Chemistry-X
PMID：
39444440
Reversible cross-linking of gelatin by a disulphide-containing bis-succinimide for tunable degradation and release
点击查看 >>
Author：
Shengbin He, Jingtong Wang, Zhao Li, Yongqiang Cao, Xueping Ning, Jian Sun, Quanzhi Chen, Min Ling
IF：
6.4430
Publish_to：
Food Chemistry-X
PMID：
37215197
Salidroside alleviates dexamethasone-induced inhibition of bone formation via transforming growth factor-beta/Smad2/3 signaling pathway
点击查看 >>
Author：
Baocheng Xie, Huan Zhou, Hongyu Liu, Shiyi Liao, Chenhui Zhou, Daohua Xu
IF：
6.3880
Publish_to：
PHYTOTHERAPY RESEARCH
PMID：
36567454
Expression and purification of soluble recombinant β-lactamases using Escherichia coli as expression host and pET-28a as cloning vector
点击查看 >>
Author：
Li Lele, Li Hui, Tian Qingwu, Ge Baosheng, Xu Xiaotong, Chi Yuanyuan, Zhao Huaizhi, Liu Yanfei, Jia Nan, Zhou Tingting, Zhu Yuanqi, Zhou Yusun
IF：
6.3520
Publish_to：
Microbial Cell Factories
PMID：
36419169
Transcription Factor FOSL1 Enhances Drug Resistance of Breast Cancer through DUSP7-Mediated Dephosphorylation of PEA15
点击查看 >>
Author：
Li Lin, Wang Nan, Xiong Youyi, Guo Guangcheng, Zhu Mingzhi, Gu Yuanting
IF：
6.3330
Publish_to：
MOLECULAR CANCER RESEARCH
PMID：
34907034
B4GALNT2 Gene Promotes Proliferation, and Invasiveness and Migration Abilities of Model Triple Negative Breast Cancer (TNBC) Cells by Interacting With HLA-B Protein
点击查看 >>
Author：
Yu Pu, Zhu Lili, Cui Kang, Du Yabing, Zhang Chaojie, Ma Wang, Guo Jia
IF：
6.2440
Publish_to：
Frontiers in Oncology
PMID：
34589428
Design of Cyclic Peptide-Based Nanospheres and the Delivery of siRNA
点击查看 >>
Author：
Junfeng Ke, Jingli Zhang, Junyang Li, Junqiu Liu, Shuwen Guan
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36292932
Direct Assembly of Bioactive Nanoparticles Constructed from Polyphenol-Nanoengineered Albumin
点击查看 >>
Author：
Haojie Zhang, Yunxiang He, Yajing Zhang, Jiezhou Pan, Tingxu Guo, Huijun Huang, Mengyuan Dai, Jiaojiao Shang, Guidong Gong, Junling Guo
IF：
6.2000
Publish_to：
BIOMACROMOLECULES
PMID：
38574372
Fucogalactan Sulfate (FS) from Laminaria japonica Regulates Lipid Metabolism in Diet-Induced Humanized Dyslipidemia Mice via an Intestinal FXR-FGF19-CYP7A1/CYP8B1 Pathway
点击查看 >>
Author：
Jiangping Song, Xingyu Lu, Denghong Liu, Yuwei Zhang, Xiaoning Zhai, Liuyang Zhou, Jie Gao
IF：
6.1000
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
37702045
Effects of Lactiplantibacillus plantarum 19-2 on immunomodulatory function and gut microbiota in mice
点击查看 >>
Author：
Xiaoran Wang, Jilang Tang, Shixia Zhang, Nuannuan Zhang
IF：
6.0640
Publish_to：
Frontiers in Microbiology
PMID：
35992718
Fingolimod protects against neurovascular unit injury in a rat model of focal cerebral ischemia/reperfusion injury
点击查看 >>
Author：
Zhu Xiao-Yu, Ma Ting-Ting, Li Yang, Zhang Ming-Qi, Zhao Liang, Liang Jia, Min Lian-Qiu
IF：
6.0580
Publish_to：
Neural Regeneration Research
PMID：
36204856
A microfluidic approach for rapid and continuous synthesis of glycoprotein-imprinted nanospheres
点击查看 >>
Author：
Yu Jin, Tingting Wang, Qianjin Li, Fenying Wang, Jianlin Li
IF：
6.0570
Publish_to：
TALANTA
PMID：
34836638
Hydroxysafflor Yellow A Alleviates Ischemic Stroke in Rats via HIF-1α, BNIP3, and Notch1-Mediated Inhibition of Autophagy
点击查看 >>
Author：
Yuliang Zhang, Yi Liu, Qian Cui, Zitong Fu, Haoyu Yu, Ao Liu, Jingjing Liu, Xiude Qin, Shaoqin Ge, Guowei Zhang
IF：
6.0050
Publish_to：
AMERICAN JOURNAL OF CHINESE MEDICINE
PMID：
35300568
Licoricidin combats gastric cancer by targeting the ICMT/Ras pathway in vitro and in vivo.
点击查看 >>
Author：
Hanwei Ma, Fahong Wu, Yinliang Bai, Tianwei Wang, Shangxian Ma, Liuqing Guo, Guiyuan Liu, Guangxian Leng, Yin Kong, Youcheng Zhang
IF：
5.9880
Publish_to：
Frontiers in Pharmacology
PMID：
36339587
Cell Penetrating Peptide-Based Self-Assembly for PD-L1 Targeted Tumor Regression
点击查看 >>
Author：
Feng Guo, Junfeng Ke, Zhengdong Fu, Wenzhao Han, Liping Wang
IF：
5.9240
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
34948105
HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis
点击查看 >>
Author：
Dan Liu, Shanshan Lin, Yueben Hu, Jianyong Xiong, Hongtao Wan, Yanglin Chen, Taohui Ding, Hu Zhao, Renjie Jiang, Zhijiang Huang, Dengke Yao, Ming Li, Xiaojian Zhu, Bo Yi
IF：
5.9000
Publish_to：
Non-coding RNA Research
PMID：
40290566
Typical Umami Ligand-Induced Binding Interaction and Conformational Change of T1R1-VFT
点击查看 >>
Author：
Ninglong Zhang, Zhiyong Cui, Mingyang Li, Yuxia Fan, Jing Liu, Wenli Wang, Yin Zhang, Yuan Liu
IF：
5.8950
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
36098631
Construction and antitumor properties of a targeted nano-drug carrier system responsive to the tumor microenvironment
点击查看 >>
Author：
Wenzhao Han, Junfeng Ke, Feng Guo, Fanwei Meng, Hui Li, Liping Wang
IF：
5.8750
Publish_to：
INTERNATIONAL JOURNAL OF PHARMACEUTICS
PMID：
34481009
LncNAP1L6 activates MMP pathway by stabilizing the m6A-modified NAP1L2 to promote malignant progression in prostate cancer
点击查看 >>
Author：
Zheng Yuxiao, Qi Feng, Li Lu, Yu Bin, Cheng Yifei, Ge Minghui, Qin Chao, Li Xiao
IF：
5.8540
Publish_to：
CANCER GENE THERAPY
PMID：
36195720
Galectin-3 Mediated Inflammatory Response Contributes to Neurological Recovery by QiShenYiQi in Subacute Stroke Model
点击查看 >>
Author：
Wang Yule, He Shuang, Liu Xinyan, Li Zhixiong, Zhu Lin, Xiao Guangxu, Du Xiaoli, Du Hongxia, Zhang Wen, Zhang Yiqian, Orgah John, Feng Yuxin, Zhang Boli, Zhu Yan
IF：
5.8110
Publish_to：
Frontiers in Pharmacology
PMID：
33953667
Zearalenone induces the senescence of cardiovascular cells in vitro and in vivo
点击查看 >>
Author：
Wang Kaihao, Zhou Min, Du Yipeng, Li Peixin, Huang Zheng
IF：
5.8000
Publish_to：
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
PMID：
36913015
An Efficient Virus-Induced Gene Silencing System for Functional Genomics Research in Walnut (Juglans regia L.) Fruits
点击查看 >>
Author：
Wang Yifan, Huang Ning, Ye Niu, Qiu Lingyu, Li Yadong, Ma Huiling
IF：
5.7540
Publish_to：
Frontiers in Plant Science
PMID：
34249033
Circ_ZFR contributes to the paclitaxel resistance and progression of non-small cell lung cancer by upregulating KPNA4 through sponging miR-195-5p
点击查看 >>
Author：
Li Junmin, Fan Rongmei, Xiao Hui
IF：
5.7220
Publish_to：
Cancer Cell International
PMID：
33407505
Knockdown of CCR3 gene inhibits Proliferation, migration and degranulation of eosinophils in mice by downregulating the PI3K/Akt pathway
点击查看 >>
Author：
Yinli Jiang, Qibin Pan, Xinhua Zhu, Jianguo Liu, Zheng Liu, Yi Deng, Wenqiang Liu, Yuehui Liu
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
36410183
Antibacterial activity mechanism of coptisine against Pasteurella multocida
点击查看 >>
Author：
Zhang Rui, Tian Shuo, Zhang Tengfei, Zhang Wenting, Lu Qin, Hu Qiao, Shao Huabin, Guo Yunqing, Luo Qingping
IF：
5.7000
Publish_to：
Frontiers in Cellular and Infection Microbiology
PMID：
37502603
LINC01564 Promotes the TMZ Resistance of Glioma Cells by Upregulating NFE2L2 Expression to Inhibit Ferroptosis
点击查看 >>
Author：
Luo Chixing, Nie Chuansheng, Zeng Yibin, Qian Kang, Li Xudong, Wang Xuan
IF：
5.6820
Publish_to：
MOLECULAR NEUROBIOLOGY
PMID：
35420382
LncRNA GAS5 regulates migration and epithelial-to-mesenchymal transition in lens epithelial cells via the miR-204-3p/TGFBR1 axis
点击查看 >>
Author：
Li Xiao, Sun Miaomiao, Cheng Anran, Zheng Guangying
IF：
5.6620
Publish_to：
LABORATORY INVESTIGATION
PMID：
34916611
Sodium Butyrate Induces Mitophagy and Apoptosis of Bovine Skeletal Muscle Satellite Cells through the Mammalian Target of Rapamycin Signaling Pathway
点击查看 >>
Author：
Yanling Ding, Pengfei Wang, Chenglong Li, Yanfeng Zhang, Chaoyun Yang, Xiaonan Zhou, Xiaowei Wang, Zonghua Su, Wenxuan Ming, Ling Zeng, Yuangang Shi, Cong-Jun Li, Xiaolong Kang
IF：
5.6000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
37686278
Effect of Homogenization Modified Rice Protein on the Pasting Properties of Rice Starch
点击查看 >>
Author：
Jianyong Wu, Shunqian Xu, Xiaoyan Yan, Xuan Zhang, Xingfeng Xu, Qian Li, Jiangping Ye, Chengmei Liu
IF：
5.5610
Publish_to：
Foods
PMID：
35681350
Fe3O4 magnetic nanoparticle-enhanced radiotherapy for lung adenocarcinoma via delivery of siBIRC5 and AS-ODN
点击查看 >>
Author：
Chen Shuzhen, Han Fushi, Huang Dongdong, Meng Jinqian, Chu Jiapeng, Wang Meng, Wang Peijun
IF：
5.5310
Publish_to：
Journal of Translational Medicine
PMID：
34372869
Fangji Huangqi decoction ameliorates membranous nephropathy through the upregulation of BNIP3-mediated mitophagy
点击查看 >>
Author：
Yuxin Wang, Yuhua Ma, Yanrong Ke, Xiaocheng Jiang, Jian Liu, Yang Xiao, Hong Zheng, Chaojun Wang, Xue Chen, Manman Shi
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
38237645
A polysaccharide from Rosa roxburghii Tratt fruit attenuates high-fat diet-induced intestinal barrier dysfunction and inflammation in mice by modulating the gut microbiota
点击查看 >>
Author：
Lei Wang, Pan Zhang, Chao Li, Fei Xu, Jie Chen
IF：
5.3960
Publish_to：
Food & Function
PMID：
34932054
LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway
点击查看 >>
Author：
Xiuyan Wang, Bin Song, Mingcui Zang, He Ji, He Yang, Shuang Jiang, Xiao Yang
IF：
5.3100
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
34309216
Bazi Bushen alleviates skin senescence by orchestrating skin homeostasis in SAMP6 mice
点击查看 >>
Author：
Zhe Xu, Boyang Gong, Zhaodong Li, Ying Wang, Zeyu Zhao, Lulu Xie, Yanfei Peng, Shuwu Zhao, Huifang Zhou, Yuhong Bian
IF：
5.3000
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
37614114
ASH1L contributes to oocyte apoptosis by regulating DNA damage
点击查看 >>
Author：
Tuo Zhang, Tianhe Ren, Huan Lin, Yuntong Tong, Jixian Zhang, Jie Nie, Yingjie Zhu, Yiting Wang, Bangming Jin, Chunlin Zhang, Tengxiang Chen, Meina He
IF：
5.2820
Publish_to：
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
PMID：
36094439
DHA/EPA-Enriched Phosphatidylcholine Suppresses Tumor Growth and Metastasis via Activating Peroxisome Proliferator-Activated Receptor γ in Lewis Lung Cancer Mice
点击查看 >>
Author：
Yuanyuan Liu, Yingying Tian, Weizhen Cai, Yao Guo, Changhu Xue, Jingfeng Wang
IF：
5.2790
Publish_to：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
PMID：
33406839
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway
点击查看 >>
Author：
Yang Wei, Feng Qihua, Li Minjing, Su Jiaqi, Wang Peiyuan, Wang Xu, Yin Yancun, Wang Xia, Zhao Mingdong
IF：
5.2460
Publish_to：
Frontiers in Molecular Biosciences
PMID：
34179090
A sensitive fluorescence biosensor based on metal ion-mediated DNAzyme activity for amplified detection of acetylcholinesterase
点击查看 >>
Author：
Xu-Hua Zhao, Xiao-Chun Dai, Ya-Nan Zhou, Han-Xiao Zhang, Xiao-Hua Cui, Xiang Zhai, Bao-Feng Yu, Zhi-Ling Song
IF：
5.2270
Publish_to：
ANALYST
PMID：
35579472
Upregulated Talin1 synergistically boosts β-estradiol-induced proliferation and pro-angiogenesis of eutopic and ectopic endometrial stromal cells in adenomyosis
点击查看 >>
Author：
Wang Yi-yi, Duan Hua, Wang Sha, Quan Yong-jun, Huang Jun-hua, Guo Zheng-chen
IF：
5.2110
Publish_to：
Reproductive Biology and Endocrinology
PMID：
33990206
Shenmai injection ameliorates doxorubicin-induced myocardial injury by suppressing autophagy-apoptosis via miR-30a
点击查看 >>
Author：
Yanyang Li, Lu Fan, Xiaoming Wang, Shichao Lv
IF：
5.2000
Publish_to：
Aging-US
PMID：
37938165
Peptides derived from sea cucumber accelerate cells proliferation and migration for wound healing by promoting energy metabolism and upregulating the ERK/AKT pathway
点击查看 >>
Author：
Zhihong Zheng, Mengqi Li, Pengfei Jiang, Na Sun, Songyi Lin
IF：
5.1950
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
35292250
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma
点击查看 >>
Author：
Ke Huang, Huihui Wang, Jia Xu, Ruiming Xu, Zelin Liu, Yi Li, Zhaoqing Xu
IF：
5.1680
Publish_to：
Biology-Basel
PMID：
35892971
Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis
点击查看 >>
Author：
Guo Zhenye, Wang Huan, Zhao Feng, Liu Min, Wang Feida, Kang Mingming, He Weifu, Lv Zhi
IF：
5.1560
Publish_to：
ARTHRITIS RESEARCH & THERAPY
PMID：
34082824
Lactobacillus extracellular vesicles alleviate alcohol-induced liver injury in mice by regulating gut microbiota and activating the Nrf-2 signaling pathway
点击查看 >>
Author：
Qianqian Jiao, Jin Liu, Lei Zhou, David J McClements, Wei Liu, Jun Luo, Shengfeng Peng
IF：
5.1000
Publish_to：
Food & Function
PMID：
39865864
Cell division control protein 42 correlates with lower disease risk and its elevation predicts better treatment response, and inhibits T-helper 17 cell differentiation in rheumatoid arthritis
点击查看 >>
Author：
Yang Yameng, Huang Li, Wu Bin
IF：
5.0930
Publish_to：
INFLAMMOPHARMACOLOGY
PMID：
35737168
CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR-153-3p/ATF2 axis and wnt/β-catenin pathway
点击查看 >>
Author：
Qi Wang, Bai Xu, Haiping Liu, Dongwei Wang, Siyang Liu, Chi He, Xiaona Feng, Limin Wang
IF：
5.0040
Publish_to：
DRUG DEVELOPMENT RESEARCH
PMID：
34981843
Effect of fermentation on structural properties and antioxidant activity of wheat gluten by Bacillus subtilis
点击查看 >>
Author：
Zhao Peng-hui, Hou Yin-Chen, Wang Zhen, Liao Ai-Mei, Pan Long, Zhang Jie, Dong Yu-Qi, Hu Zhe-Yuan, Huang Ji-Hong, Ou Xing-Qi
IF：
5.0000
Publish_to：
Frontiers in Nutrition
PMID：
36908923
ILC2s induce adaptive Th2-type immunity in different stages of tuberculosis through the Notch-GATA3 pathway
点击查看 >>
Author：
Qifeng Li, Jianfeng Zhang, Lanhong Ma, Chao Wu, Jing Zhao, Wenlong Guan, Xiaochun Li, Xiaohong Yang, Fuqiang Wen
IF：
4.9320
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
34862127
Discovery of Hepatotoxic Equivalent Markers and Mechanism of Polygonum multiflorum Thunb. by Metabolomics Coupled with Molecular Docking
点击查看 >>
Author：
Yinhuan Zhang, Lirong Liu, Menghan Feng, Hao Wu, Yihang Dai, Zhixin Jia, Cong Fang, Mingyan Liu, Xiaoning Yan, Meixia Zhu, Beibei Huang, Biqiong Qu, Hongbin Xiao
IF：
4.9270
Publish_to：
MOLECULES
PMID：
36615221
Chromatin Licensing and DNA Replication Factor 1 (CDT1) Is a Potential Prognostic Biomarker Involved in the Malignant Biological Behavior of Glioma
点击查看 >>
Author：
Tiange Chen, Jiawei Meng, Ke Yu, Tianxiang Huang, Jiannong Zhao
IF：
4.9000
Publish_to：
ACS Pharmacology & Translational Science
PMID：
39416957
miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis
点击查看 >>
Author：
Fengying Chen, Yuzhen Ning, Jingying Liu, Ming Lian, Juanjuan Wang, Hongwei Dan
IF：
4.8000
Publish_to：
JOURNAL OF BIOLOGICAL CHEMISTRY
PMID：
37001814
VqBGH40a isolated from Chinese wild Vitis quinquangularis degrades trans-piceid and enhances trans-resveratrol
点击查看 >>
Author：
Chaohui Yan, Na Yang, Xinqi Wang, Yuejin Wang
IF：
4.7290
Publish_to：
PLANT SCIENCE
PMID：
34315603
A Single-Step Method for Harvesting Influenza Viral Particles from MDCK Cell Culture Supernatant with High Yield and Effective Impurity Removal
点击查看 >>
Author：
Sixu Liu, Jingqi Li, Qingtian Cheng, Kangyi Duan, Zhan Wang, Shuang Yan, Shuaishuai Tian, Hairui Wang, Shaobin Wu, Xinkui Lei, Yu Yang, Ningning Ma
IF：
4.7000
Publish_to：
Viruses-Basel
PMID：
38793649
CKAP2L, a crucial target of miR-326, promotes prostate cancer progression
点击查看 >>
Author：
Li Qi, Yan Mo, Wang Chunhui, Wang Kaibin, Bao Guochang
IF：
4.6380
Publish_to：
BMC CANCER
PMID：
35715760
Anti-Inflammatory Effects of Camellia fascicularis Polyphenols via Attenuation of NF-κB and MAPK Pathways in LPS-Induced THP-1 Macrophages
点击查看 >>
Author：
Miaozi Gao, Xiaowei Peng, Junrong Tang, Jia Deng, Fang Wang, Yingjun Zhang, Ping Zhao, Huan Kan, Yun Liu
IF：
4.6310
Publish_to：
Journal of Inflammation Research
PMID：
35177920
PGM5P3-AS1 regulates MAP1LC3C to promote cell ferroptosis and thus inhibiting the malignant progression of triple-negative breast cancer
点击查看 >>
Author：
Qi Liqiang, Sun Bo, Yang Beibei, Lu Su
IF：
4.6240
Publish_to：
BREAST CANCER RESEARCH AND TREATMENT
PMID：
35325342
Triterpenoid and Coumarin Isolated from Astilbe grandis with Anti-Inflammatory Effects through Inhibiting the NF-κB Pathway in LPS-Induced RAW264.7 Cells
点击查看 >>
Author：
Jin-Fang Luo, Lan Yue, Tian-Tai Wu, Chen-Liang Zhao, Jiang-Hai Ye, Kang He, Juan Zou
IF：
4.6000
Publish_to：
MOLECULES
PMID：
37570700
Long non-coding DANCR targets miR-185-5p to upregulate LIM and SH3 protein 1 promoting prostate cancer via the FAK/PI3K/AKT/GSK3β/snail pathway
点击查看 >>
Author：
Wendong Sun, Shulu Zu, Guangfeng Shao, Wenzhen Wang, Fangxin Gong
IF：
4.5650
Publish_to：
JOURNAL OF GENE MEDICINE
PMID：
33885171
Proteo-Transcriptomic Characterization of Sirex nitobei (Hymenoptera: Siricidae) Venom
点击查看 >>
Author：
Chenglong Gao, Lili Ren, Ming Wang, Zhengtong Wang, Ningning Fu, Huiying Wang, Xiaochen Wang, Tegen Ao, Wensheng Du, Zijin Zheng, Huadong Li, Juan Shi
IF：
4.5460
Publish_to：
Toxins
PMID：
34437434
Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis
点击查看 >>
Author：
Zhao Xin, Chen Linlin, Wu Jingxun, You Jun, Hong Qingqi, Ye Feng
IF：
4.5400
Publish_to：
Biology Direct
PMID：
34727954
Regulation of Tomato Fruit Autophagic Flux and Promotion of Fruit Ripening by the Autophagy-Related Gene SlATG8f
点击查看 >>
Author：
Cen Wen, Taimin Luo, Zhuo He, Yunzhou Li, Jianmin Yan, Wen Xu
IF：
4.5000
Publish_to：
Plants-Basel
PMID：
37765504
Certification of visinin-like protein-1 (VILIP-1) certified reference material by amino acid-based and sulfur-based liquid chromatography isotope dilution mass spectrometry
点击查看 >>
Author：
Zang Yang, Zhou Xirui, Pan Mengyun, Lu Yanli, Liu Hangrui, Xiong Jinping, Feng Liuxing
IF：
4.4780
Publish_to：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
PMID：
36342508
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation
点击查看 >>
Author：
Zhi Cui, Shiqun Sun, Jia Li, Jianing Li, Tong Sha, Jie He, Linjing Zuo
IF：
4.4730
Publish_to：
CELL BIOLOGY INTERNATIONAL
PMID：
35128752
Systematic analysis of the mechanism of hydroxysafflor yellow A for treating ischemic stroke based on network pharmacology technology
点击查看 >>
Author：
Qian Cui, Yu-hui Ma, Hao-yu Yu, Yu-liang Zhang, Xiu-de Qin, Shao-qin Ge, Guo-wei Zhang
IF：
4.4320
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
34302817
Juglone Inactivates Pseudomonas aeruginosa through Cell Membrane Damage, Biofilm Blockage, and Inhibition of Gene Expression
点击查看 >>
Author：
Qiqi Han, Xinpeng Yan, Runguang Zhang, Guoliang Wang, Youlin Zhang
IF：
4.4120
Publish_to：
MOLECULES
PMID：
34641398
Bacillus subtilis HW2 enhances growth performance and alleviates gut injury via attenuation of endoplasmic reticulum stress and regulation of gut microbiota in broilers under necrotic enteritis challenge
点击查看 >>
Author：
Peng Chen, Huimin Lv, Mengmeng Du, Weiyong Liu, Chuanyan Che, Jinshan Zhao, Huawei Liu
IF：
4.4000
Publish_to：
POULTRY SCIENCE
PMID：
38547540
KIF20B Promotes Cell Proliferation and May Be a Potential Therapeutic Target in Pancreatic Cancer
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Author：
Jing Chen, Cui-Cui Zhao, Fei-Ran Chen, Guo-Wei Feng, Fei Luo, Tao Jiang
IF：
4.3750
Publish_to：
Journal of Oncology
PMID：
34539784
Total flavonoids of Oxytropis falcata Bunge have a positive effect on idiopathic pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway
点击查看 >>
Author：
Xin-ze Li, Xue-lin Wang, Yan-jun Wang, Qian-kun Liang, Yang Li, Yan-wen Chen, Hai-xia Ming
IF：
4.3600
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
34826543
Structural and Emulsifying Properties of Soybean Protein Isolate–Sodium Alginate Conjugates under High Hydrostatic Pressure
点击查看 >>
Author：
Zihuan Wang, Shaoying Gong, Yucong Wang, Danyi Liu, Jianchun Han
IF：
4.3500
Publish_to：
Foods
PMID：
34829111
Wilms tumor 1 associated protein promotes epithelial mesenchymal transition of gastric cancer cells by accelerating TGF-β and enhances chemoradiotherapy resistance
点击查看 >>
Author：
Liu Yu, Da Mingxu
IF：
4.3220
Publish_to：
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
PMID：
36030434
Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin
点击查看 >>
Author：
Jin Chen, Min Gong, Zhuo Huang, Fang Wang, Yajing Wang, Zuquan Hu, Zhu Zeng, Yun Wang
IF：
4.3190
Publish_to：
Drug Design Development and Therapy
PMID：
35256843
LncRNA HOXA10-AS promotes the progression of esophageal carcinoma by regulating the expression of HOXA10
点击查看 >>
Author：
Jinghua Kuai, Kangkang Wu, Ting Han, Wenzhe Zhai, Ruijie Sun
IF：
4.3000
Publish_to：
CELL CYCLE
PMID：
36588458
Overexpression of VvPPR1, a DYW-type PPR protein in grape, affects the phenotype of Arabidopsis thaliana leaves
点击查看 >>
Author：
Yi-He Yu, Xu-Fei Li, Sheng-Di Yang, Song-Qi Li, Xiang-Xuan Meng, Hai-Nan Liu, Mao-Song Pei, Tong-Lu Wei, Yu-Jie Zhang, Da-Long Guo
IF：
4.2700
Publish_to：
PLANT PHYSIOLOGY AND BIOCHEMISTRY
PMID：
34004557
Ameliorative effect of recombinant human lactoferrin on the premature ovarian failure in rats after cyclophosphamide treatments
点击查看 >>
Author：
Li Shubin, Liu Mengnan, Ma Hongmeng, Jin Qin, Ma Yuzhen, Wang Chunyu, Ren Jingyu, Liu Gang, Dai Yanfeng
IF：
4.2340
Publish_to：
Journal of Ovarian Research
PMID：
33478578
The Anti-Inflammatory Effects of Formononetin, an Active Constituent of Pueraria montana Var. Lobata, via Modulation of Macrophage Autophagy and Polarization
点击查看 >>
Author：
Linyi Xu, Shuo Zhou, Jing Li, Wenbo Yu, Wenyi Gao, Haoming Luo, Xiaoxue Fang
IF：
4.2000
Publish_to：
MOLECULES
PMID：
39795251
Rapid Eye Movement Sleep Deprivation Combined With Fluoxetine Protects Against Depression-Induced Damage and Apoptosis in Rat Hippocampi via A1 Adenosine Receptor
点击查看 >>
Author：
Ju Xuan, Wang Shengdong, Yan Pan, Zhu Chunyan, Hu Xiwen, Dong Jiezheng, Tan Zhonglin
IF：
4.1570
Publish_to：
Frontiers in Psychiatry
PMID：
34335318
Propofol Inhibits the Progression of Cervical Cancer by Regulating HOTAIR/miR-129-5p/RPL14 Axis
点击查看 >>
Author：
Nai Sun, Wei Zhang, Jiaying Liu, Xiaochen Yang, Qinjun Chu
IF：
4.1470
Publish_to：
OncoTargets and Therapy
PMID：
33505161
Developing novel oenological tannins from 44 plants sources by assessing astringency and color in model wine
点击查看 >>
Author：
Chenyaqiong Cheng, Pei Liu, Pengtao Zhao, Guorong Du, Shengnan Wang, Hui Liu, Xiaomeng Cao, Qinghao Zhao, Xiaoyu Wang
IF：
4.1250
Publish_to：
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
PMID：
36189836
Panax notoginseng saponins improves healing of high glucose-induced wound through the GSK-3β/β-catenin pathway
点击查看 >>
Author：
Ting Lei, Ya Gao, Yuhong Duan, Chunli Cui, Li Zhang, Mingming Si
IF：
4.1090
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
35385194
SAA1 exacerbates pancreatic β-cell dysfunction through activation of NF-κB signaling in high-fat diet-induced type 2 diabetes mice
点击查看 >>
Author：
Qi Wang, Hong Li, Henghao Lu, Shumin Wang, Yuxiu Li, Zhenfen Zhang, Jing Han, Zhe Yang, Yanping Yang, Yan Hong
IF：
4.1000
Publish_to：
MOLECULAR AND CELLULAR ENDOCRINOLOGY
PMID：
37574124
miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis
点击查看 >>
Author：
Zhang Kailin, Fu WenYi, Zhao Shuai, Jiao Ting, Wu Dan, Wang YueJiao
IF：
4.0920
Publish_to：
INFLAMMATION
PMID：
34160728
Oxidized low-density lipoprotein activates extracellular signal-regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells
点击查看 >>
Author：
Qi Zhang, Wenyan Lin, Limin Tian, Baoshan Di, Jing Yu, Xiang'e Niu, Jing Liu
IF：
4.0290
Publish_to：
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
PMID：
33694195
Study on the mechanism of enhanced gel strength of heat-induced egg white by shikimic acid braising
点击查看 >>
Author：
Hui Xue, Meng Xu, Guowen Zhang, Ping Wang, Lin Yu, Ying Zhao, Yonggang Tu, Yan Zhao
IF：
4.0140
Publish_to：
POULTRY SCIENCE
PMID：
35278755
Establishment of an indirect ELISA detection method for porcine reproductive and respiratory syndrome virus NSP4
点击查看 >>
Author：
Mengmeng Zhao, Chen Lv, Jiankun Pang, Zhiyu Yang, Huiyang Sha
IF：
4.0000
Publish_to：
Frontiers in Microbiology
PMID：
40041872
Two single mutations in carboxylesterase 001C improve fenvalerate hydrolase activity in Helicoverpa armigera
点击查看 >>
Author：
Jing-jing Xu, Yong-mei Chang, Mei Lu, Yuan Tie, Yan-ling Dong, Guang-you Chen, Zhi-qing Ma, Xi-li Liu, Yong-qiang Li
IF：
3.9630
Publish_to：
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
PMID：
34802519
Effect of vitamin D3 on lipid droplet growth in adipocytes of mice with HFD-induced obesity
点击查看 >>
Author：
Jingjing Zhang, Yuanfan Zhang, Yong Zhou, Wenxin Zhao, Jialu Li, Dan Yang, Lian Xiang, Tingwan Du, Ling Ma
IF：
3.9000
Publish_to：
Food Science & Nutrition
PMID：
37823117
Biofunctional Extracellular Matrix-Polycaprolactone-Hydroxyapatite Scaffold and Synovium Mesenchymal Stem Cells/Chondrocytes for Repairing Cartilage Defects
点击查看 >>
Author：
Yingjie Xu, Bo Shao, Xuemin Zeng, Zhiqiang Song, Mengying Jia, Zhongcheng Gong
IF：
3.8450
Publish_to：
Tissue Engineering Part A
PMID：
33397197
Anti-inflammatory effects of the prostaglandin D2/prostaglandin DP1 receptor and lipocalin-type prostaglandin D2 synthase/prostaglandin D2 pathways in bacteria-induced bovine endometrial tissue
点击查看 >>
Author：
Wu Jindi, Bai Fan, Mao Wei, Liu Bo, Yang Xiaolin, Zhang Jing, Li Tingting, Borjigin Gerelt, Cao Jinshan
IF：
3.8290
Publish_to：
VETERINARY RESEARCH
PMID：
36435808
GLIS3, a novel prognostic indicator of gastric adenocarcinoma, contributes to the malignant biological behaviors of tumor cells via modulating TGF-β1/TGFβR1/Smad1/5 signaling pathway
点击查看 >>
Author：
Yue Zhang, Bo Wang, Hui Song, Min Han
IF：
3.8000
Publish_to：
CYTOKINE
PMID：
37651918
Decabromodiphenyl ether causes insulin resistance and glucose and lipid metabolism disorders in mice
点击查看 >>
Author：
Ayiguli Alimu, Haiqiemuhan Abudureman, Yong-Zhi Wang, Mei-Yan Li, Jia-Sui Wang, Zao-Ling Liu
IF：
3.7630
Publish_to：
World Journal of Diabetes
PMID：
34512892
Study on the mechanism of Shenkang injection in the treatment of chronic renal failure based on the strategy of "Network pharmacology—Molecular docking—Key target validation"
点击查看 >>
Author：
Lin Zhou, Xiaohui Wang, Zhi Sun, Xiaoyue Bao, Lianping Xue, Zhanmei Xu, Pengfei Dong, Jinlan Xia
IF：
3.7000
Publish_to：
PLoS One
PMID：
37796994
Circ_TLK1 knockdown alleviates oxygen–glucose deprivation/reoxygenation-induced PC12 cell injury by regulating microRNA-136-5p/follistatin like-1 axis
点击查看 >>
Author：
Zhenduo Zhang, Jinbo He, Baoliang Wang
IF：
3.6980
Publish_to：
EUROPEAN JOURNAL OF NEUROSCIENCE
PMID：
35766911
Direct separation and purification of α-lactalbumin from cow milk whey by aqueous two-phase flotation of thermo-sensitive polymer/phosphate
点击查看 >>
Author：
Bin Jiang, Linlin Wang, Meichan Wang, Shuang Wu, Xiaojing Wang, Dongmei Li, Chunhong Liu, Zhibiao Feng, Yujie Chi
IF：
3.6390
Publish_to：
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
PMID：
33420726
CircPRDM2 Contributes to Doxorubicin Resistance of Osteosarcoma by Elevating EZH2 via Sponging miR-760
点击查看 >>
Author：
Jianjun Yuan, Yan Liu, Quan Zhang, Zhishuai Ren, Guang Li, Rong Tian
IF：
3.6020
Publish_to：
Cancer Management and Research
PMID：
34103997
Silencing long noncoding RNA LINC01133 suppresses pancreatic cancer through regulation of microRNA-1299-dependent IGF2BP3
点击查看 >>
Author：
Sumei Li, Fengru Jiang, Feiyu Chen, Yinzhao Deng, Haiying Huang
IF：
3.6000
Publish_to：
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
PMID：
37718503
Production of hesperetin from naringenin in an engineered Escherichia coli consortium
点击查看 >>
Author：
Juan Liu, Miaomiao Tian, Zhen Wang, Feiyao Xiao, Xu Huang, Yang Shan
IF：
3.5950
Publish_to：
JOURNAL OF BIOTECHNOLOGY
PMID：
35192875
TPX2 mediates prostate cancer epithelial-mesenchymal transition through CDK1 regulated phosphorylation of ERK/GSK3β/SNAIL pathway
点击查看 >>
Author：
Boya Zhang, Mingpeng Zhang, Qi Li, Yanjie Yang, Zhiqun Shang, Jun Luo
IF：
3.5750
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
33556637
CIRCKLHL2 KNOCKDOWN ALLEVIATES SEPSIS-INDUCED ACUTE LUNG INJURY BY REGULATING MIR-29B-3P MEDIATED ROCK1 EXPRESSION DOWN-REGULATION
点击查看 >>
Author：
Li Nan, Li Yuqiang, Wu Bin, Sun Rongli, Zhao Mingzhou, Hu Zhansheng
IF：
3.5330
Publish_to：
SHOCK
PMID：
36476974
Impact of High Hydrostatic Pressure on the Physicochemical Characteristics, Functional Properties, Structure, and Bioactivities of Tenebrio molitor Protein
点击查看 >>
Author：
Can Zhang, Huayi Suo, Jiajia Song
IF：
3.5000
Publish_to：
Food Science & Nutrition
PMID：
39968209
β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows
点击查看 >>
Author：
Zhihao Dong, Xudong Sun, Yan Tang, Shengbin Luo, Hongdou Jia, Qiushi Xu, Qianming Jiang, Juan J. Loor, Wei Xu, Chuang Xu
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
36105004
circCNN2 Accelerates Cell Proliferation and Invasion in Lung Squamous Cell Carcinoma via Regulating miR-184/E2F1 and Activating MAPK Signaling Pathway
点击查看 >>
Author：
Shan Hu, Peng Cao, Kangle Kong, Peng Han, Jiaqi Yue, Yu Deng, Fan Li, Bo Zhao
IF：
3.4640
Publish_to：
DISEASE MARKERS
PMID：
36016851
Losartan Attenuates Atherosclerosis in Uremic Mice by Regulating Treg/Th17 Balance via Mediating PTEN/PI3K/Akt Pathway
点击查看 >>
Author：
Wei Shanzhai, Sun Jie, Li Yibei, Xu Kangchun, Wang Man, Zhang Yilai
IF：
3.4570
Publish_to：
NEPHRON
PMID：
35176745
Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy
点击查看 >>
Author：
Bing Jiang, Longfei Feng, Tao Yang, Wenjing Guo, Yangyang Li, Tao Wang, Chengguang Liu, Haixiang Su
IF：
3.4230
Publish_to：
Molecular Medicine Reports
PMID：
36579660
MicroRNA-20a-5p inhibits the autophagy and cisplatin resistance in ovarian cancer via regulating DNMT3B-mediated DNA methylation of RBP1
点击查看 >>
Author：
Hui Li, Yuansheng Lei, Shuangxue Li, Feng Li, Jieyun Lei
IF：
3.4210
Publish_to：
REPRODUCTIVE TOXICOLOGY
PMID：
34990753
KIF11 Promotes Proliferation of Hepatocellular Carcinoma among Patients with Liver Cancers
点击查看 >>
Author：
Zhan-Dong Hu, Ying Jiang, Hong-Mei Sun, Jing-wen Wang, Li-Li Zhai, Zhi-Qi Yin, Jun Yan
IF：
3.4110
Publish_to：
Biomed Research International
PMID：
33490265
Analysis of compatibility mechanism of shenxiong glucose injection after multiple dosing based on differences of PK-PD correlation and cytochrome P450 enzyme
点击查看 >>
Author：
Jia Sun, Rong Li, Jingya Zhang, Yong Huang, Yuan Lu, Chunhua Liu, Yongjun Li, Ting Liu
IF：
3.4000
Publish_to：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
PMID：
38103414
CircKIF2A contributes to cell proliferation, migration, invasion and glycolysis in human neuroblastoma by regulating miR-129-5p/PLK4 axis
点击查看 >>
Author：
Yang Yiheng, Pan Hongli, Chen Jie, Zhang Zhonghua, Liang Minna, Feng Xunqiang
IF：
3.3960
Publish_to：
MOLECULAR AND CELLULAR BIOCHEMISTRY
PMID：
33630225
IL-33 Alleviates Postoperative Cognitive Impairment by Inhibiting Hippocampal Inflammation and Upregulating Excitatory Synaptic Number in Aged Mice
点击查看 >>
Author：
Qi Li, Yuqian Zhao, Chuanchuan Shi, Xuemin Song
IF：
3.3330
Publish_to：
Brain Sciences
PMID：
36138980
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets
点击查看 >>
Author：
Ruixue Li, Jianyan Qin, Ziyuan Wang, Fenghong Lv, Jiasen Guo, Hong Zhu, Youguang Huang
IF：
3.3220
Publish_to：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
PMID：
36442237
Knockdown of circ-FANCA alleviates LPS-induced HK2 cell injury via targeting miR-93-5p/OXSR1 axis in septic acute kidney injury
点击查看 >>
Author：
Li Heyun, Zhang Xia, Wang Peng, Zhou Xiaoyan, Liang Haiying, Li Caoni
IF：
3.3200
Publish_to：
Diabetology & Metabolic Syndrome
PMID：
33468219
Phosphotyrosine picked threonine kinase stimulates proliferation of human osteosarcoma cells in vitro and in vivo
点击查看 >>
Author：
Zhe-Xiang Wang, Shao-Chun Ren, Jing Ren
IF：
3.3180
Publish_to：
Archives of Medical Science
PMID：
35591845
Exosomal MiR-423–3p inhibits macrophage M2 polarization to suppress the malignant progression of cervical cancer
点击查看 >>
Author：
Xin Yan, Sanyuan Zhang, Junmei Jia, Jiaolin Yang, Yilai Song, Haoran Duan
IF：
3.3090
Publish_to：
PATHOLOGY RESEARCH AND PRACTICE
PMID：
35609397
Baicalin mitigates Nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick
点击查看 >>
Author：
Guanming Tian, Cheng Huang, Zhengqing Li, Zhihua Lu, Chenlu Feng, Yu Zhuang, Guyue Li, Ping Liu, Guoliang Hu, Xiaona Gao, Xiaoquan Guo
IF：
3.3000
Publish_to：
VETERINARY MICROBIOLOGY
PMID：
37866328
Evodiamine suppresses the progression of non-small cell lung carcinoma via endoplasmic reticulum stress-mediated apoptosis pathway in vivo and in vitro
点击查看 >>
Author：
Yuting Li, Yuming Wang, Xiaoqun Wang, Lulu Jin, Lu Yang, Jinli Zhu, Hongwu Wang, Fang Zheng, Huantian Cui, Xiaojiang Li, Yingjie Jia
IF：
3.2980
Publish_to：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
PMID：
35388733
Rapamycin inhibits the progression of human acute myeloid leukemia by regulating the circ_0094100/miR-217/ATP1B1 axis
点击查看 >>
Author：
Jiufang Cao, Shihua Huang, Xiaoming Li
IF：
3.2490
Publish_to：
EXPERIMENTAL HEMATOLOGY
PMID：
35901982
Reversibility of the gel, rheological, and structural properties of alcohol pretreated fish gelatin: Effect of alcohol types
点击查看 >>
Author：
Shijie Cen, Wenwen Yu, Wenge Yang, Qiaoming Lou, Tao Huang
IF：
3.2230
Publish_to：
JOURNAL OF TEXTURE STUDIES
PMID：
34426973
The Mechanism of miR-155/miR-15b Axis Contributed to Apoptosis of CD34+ Cells by Upregulation of PD-L1 in Myelodysplastic Syndromes
点击查看 >>
Author：
MeiWan Cao, BaoLing Peng, WanFu Xu, PeiYu Chen, HuiWen Li, Yang Cheng, Huan Chen, LiPing Ye, Jing Xie, HongLi Wang, Lu Ren, LiYa Xiong, JingNan Zhu, XiangYe Xu, LanLan Geng, SiTang Gong
IF：
3.2000
Publish_to：
Mediterranean Journal of Hematology and Infectious Diseases
PMID：
37435035
Effects of stewing with tea polyphenol on the gel properties, microstructure, and secondary structure of boiled egg white
点击查看 >>
Author：
Hui Xue, Meng Xu, Guowen Zhang, Feng Feng, Yuting Wang, Danhui Cao, Yonggang Tu, Yan Zhao
IF：
3.1670
Publish_to：
JOURNAL OF FOOD SCIENCE
PMID：
34564852
Circular RNA circ_0010729 Knockdown Attenuates Oxygen–Glucose Deprivation-Induced Human Cardiac Myocytes Injury by miR-338-3p/CALM2 Axis
点击查看 >>
Author：
Ma Bocong, Zhao Ming, Guo Zhihao
IF：
3.1050
Publish_to：
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
PMID：
33951696
Gandouling alleviates nerve injury through PI3K/Akt/FoxO1 and Sirt1/FoxO1 signaling pathway to inhibit autophagy in the rats model of Wilson's disease
点击查看 >>
Author：
Li Chen, Wangyang Xu, Yuting Zhang, Hao Chen, Yanquan Han
IF：
3.1000
Publish_to：
Brain and Behavior
PMID：
38010098
USP7 Enables Immune Escape of Glioma Cells by Regulating PD-L1 Expression
点击查看 >>
Author：
Bing Li, Bin Wang
IF：
3.0440
Publish_to：
IMMUNOLOGICAL INVESTIGATIONS
PMID：
35852892
Pyroptosis inhibition alleviates potassium oxonate- and monosodium urate-induced gouty arthritis in mice
点击查看 >>
Author：
Tian Jing, Wang Baichuan, Xie Bin, Liu Xinwei, Zhou Dapeng, Hou Xuening, Xiang Liangbi
IF：
3.0230
Publish_to：
Modern Rheumatology
PMID：
33705241
Effects of Puerarin Combined with PLGA/TCP/Puerarin on Osteocalcin and Sialoprotein of Mandibular Defects
点击查看 >>
Author：
Ying Guo, Qianqian Zhang, Nu Mi, Chunmei Li, Xuechao Lv, Hong Wang
IF：
3.0090
Publish_to：
Contrast Media & Molecular Imaging
PMID：
36128172
Inducible co-stimulator inhibits lipid phagocytosis of human aortic smooth muscle cells by down-regulating CD36 expression
点击查看 >>
Author：
Meng Liang, Xuemin Guo, Heming Wu, Zhixiong Zhong
IF：
3.0050
Publish_to：
Journal of Thoracic Disease
PMID：
35242376
NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma
点击查看 >>
Author：
Zhang Meixia, Wang Zhonghou, Yang Guang, Han Linfu, Wang Xiaofeng
IF：
3.0000
Publish_to：
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
PMID：
37848756
MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch
点击查看 >>
Author：
Yushi Cao, Zhongwen Cao, Weitie Wang, Xiangyu Jie, Lei Li
IF：
2.9520
Publish_to：
Molecular Medicine Reports
PMID：
34212977
Isolation of female germline stem cells from neonatal piglet ovarian tissue and differentiation into oocyte-like cells
点击查看 >>
Author：
Chunyu Wang, Qi Sun, Shubin Li, Gang Liu, Jingyu Ren, Yuan Li, Xiangxiang Ding, Jie Zhu, Yanfeng Dai
IF：
2.9230
Publish_to：
THERIOGENOLOGY
PMID：
36525858
circGRAMD1B contributes to migration, invasion and epithelial-mesenchymal transition of lung adenocarcinoma cells via modulating the expression of SOX4
点击查看 >>
Author：
Liu Xingjun, Wang Yi, Zhou Guixing, Zhou Jinbo, Tian Zhongmin, Xu Jie
IF：
2.9000
Publish_to：
FUNCTIONAL & INTEGRATIVE GENOMICS
PMID：
36867268
CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma
点击查看 >>
Author：
Qian Yu, Cheng Baochun, Luo Jing, Hu Yangchun, Gao Lu, Cheng Hongwei
IF：
2.8660
Publish_to：
JOURNAL OF MOLECULAR NEUROSCIENCE
PMID：
35416616
Long Non-coding RNA SPAG5-AS1 Attenuates Diabetic Retinal Vascular Dysfunction by Inhibiting Human Retinal Microvascular Endothelial Cell Proliferation, Migration, and Tube Formation by Regulating the MicroRNA-1224-5p/IRS-1 Axis
点击查看 >>
Author：
Su XingJie, Yang XiaoTian, Liu HongWei
IF：
2.8600
Publish_to：
MOLECULAR BIOTECHNOLOGY
PMID：
36346578
Paeoniflorin Can Improve Acute Lung Injury Caused by Severe Acute Pancreatitis through Nrf2/ARE Pathway
点击查看 >>
Author：
Yanyan Hu, Wei Yang
IF：
2.8090
Publish_to：
Computational and Mathematical Methods in Medicine
PMID：
35586665
The TLR4/NF-κB signaling pathway-mediated type 2 skewing of T helper cell in cough variant asthma was counteracted by ethanol extract of Anacyclus pyrethrum root
点击查看 >>
Author：
Jun Zheng, Rui Zhang, Changjiang Liu, Hao Yang, Xiaoyue Jin
IF：
2.8000
Publish_to：
IMMUNOBIOLOGY
PMID：
36990039
Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis
点击查看 >>
Author：
Wei Yan, Jing Jianhong, Peng Zhiping, Liu Xiaoqian, Wang Xueyang
IF：
2.7630
Publish_to：
BMC Endocrine Disorders
PMID：
33781239
Longitudinal Expression of Testicular TAS1R3 from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs
点击查看 >>
Author：
Ting Gong, Weiyong Wang, Houqiang Xu, Yi Yang, Xiang Chen, Lijie Meng, Yongjian Xu, Ziqing Li, Sufang Wan, Qi Mu
IF：
2.7520
Publish_to：
Animals
PMID：
33567555
Chi-miR-3880 mediates the regulatory role of interferon gamma in goat mammary gland
点击查看 >>
Author：
Yue Zhang, Jidan Liu, Guanglin Niu, Qiong Wu, Binyun Cao
IF：
2.7000
Publish_to：
DEVELOPMENTAL BIOLOGY
PMID：
37182733
Serum epithelial membrane protein 1 serves as a feasible biomarker in extrahepatic cholangiocarcinoma.
点击查看 >>
Author：
Li X, Yan L, Xue H
IF：
2.6590
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS
PMID：
34569869
Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway
点击查看 >>
Author：
Jun-Fei Li, Xiao-Rong Zheng, Hong-Yan Zhang, Chang-Ming Shen, Guo-xin Shen, Jian-Wei Jiang
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
36285158
Effect of Gegen Qinlian Decoction on Hepatic Gluconeogenesis in ZDF Rats with Type 2 Diabetes Mellitus Based on the Farnesol X Receptor/Ceramide Signaling Pathway Regulating Mitochondrial Metabolism and Endoplasmic Reticulum Stress
点击查看 >>
Author：
Qi Zhou, Ning Song, Shi-qi Wang, Yan Wang, Yi-kun Zhao, Xiang-dong Zhu
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
34422083
Astragaloside IV ameliorates insulin induced insulin resistance in HepG2 cells through reactive oxygen species mediated c-Jun N-terminal kinase pathway
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Author：
Xiaomei YE, Xiaowei XING, Kangrui YUAN, Dongming WANG, Dudu WU, Zhi CHEN, Zhiqiang YU
IF：
2.6000
Publish_to：
Journal of Traditional Chinese Medicine
PMID：
36639996
LncRNA CASC2 alleviates renal interstitial inflammation and fibrosis through MEF2C downregulation-induced hinderance of M1 macrophage polarizationEffects of lncRNA CASC2 on RIF
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Author：
Hu Jinping, Zhang Xiaoyan, Ma Feng, Huang Chen, Jiang Yali
IF：
2.5000
Publish_to：
NEPHRON
PMID：
38142674
Hydrogen regulates the M1/M2 polarization of alveolar macrophages in a rat model of chronic obstructive pulmonary disease
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Author：
Jing-chao Su, Yi Zhang, Chen Cheng, Yi-nan Zhu, Yu-meng Ye, Yong-kang Sun, Shui-ying Xiang, Yuan Wang, Zi-bing Liu, Xin-fang Zhang
IF：
2.4590
Publish_to：
EXPERIMENTAL LUNG RESEARCH
PMID：
34282696
Glycosylated protein 4-deficient PRRSV in complementing cell line shows low virus titer
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Author：
Hao Guo, Wudong Gaowa, Hongzhe Zhao, Chunyu Liu, Lina Hou, Yongjun Wen, Fengxue Wang
IF：
2.4000
Publish_to：
RESEARCH IN VETERINARY SCIENCE
PMID：
36958176
Transcription factor ZEB1 regulates PLK1-mediated SKA3 phosphorylation to promote lung cancer cell proliferation, migration and cell cycle
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Author：
Ning Guangyao, Lu Chen, Chen Yu, Jiang Menglong, Si Panpan, Zhang Renquan
IF：
2.3890
Publish_to：
ANTI-CANCER DRUGS
PMID：
36728910
Overexpression of long non-coding RNA XIST promotes IL-1β-induced degeneration of nucleus pulposus cells through targeting miR-499a-5p
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Author：
Jun He, Jing Yang, Tulan Shen, Jian He
IF：
2.3650
Publish_to：
MOLECULAR AND CELLULAR PROBES
PMID：
33722663
Honokiol regulates endoplasmic reticulum stress by promoting the activation of the sirtuin 1-mediated protein kinase B pathway and ameliorates high glucose/high fat-induced dysfunction in human umbilical vein endothelial cells
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Author：
Hong Ye, Ying Meng
IF：
2.3490
Publish_to：
ENDOCRINE JOURNAL
PMID：
33952780
Host miR-4301 promotes rotavirus replication via PPP1R3D in Caco-2 cells
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Author：
Lijun Song, Xiaotong Wang, Peicheng Zhong, Jiabo Chen, Zhi Tang, Xuemei Zhu, Yang Chen, Guiqin Dai, Yujing Zhou, Feng Li, Yuxuan Feng, Wenchang Zhao
IF：
2.3270
Publish_to：
JOURNAL OF MEDICAL VIROLOGY
PMID：
34260071
miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting NOH-1
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Author：
Lili TAN, Limin LIU, Jian YAO, Chenghao PIAO
IF：
2.3190
Publish_to：
EXPERIMENTAL ANIMALS
PMID：
33658472
The Role and Potential Regulatory Mechanism of STING Modulated Macrophage Apoptosis and Differentiation in Severe Acute Pancreatitis-Associated Lung Injury
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Author：
Yiqiu Peng, Yingying Li, Yuxi Yang, Tingjuan Shi, Ruixia Liu, Yingyi Luan, Chenghong Yin
IF：
2.3000
Publish_to：
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
PMID：
37819622
Circ-BICC1 Knockdown Alleviates Lipopolysaccharide (LPS)-Induced WI-38 Cell Injury Through miR-338-3p/MYD88 Axis
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Author：
Wang Jing, Li Guokai, Lin Sheng, Cheng Ling
IF：
2.2200
Publish_to：
BIOCHEMICAL GENETICS
PMID：
35809112
Sperm-borne lncRNA loc100847420 improves development of early bovine embryos
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Author：
Heqiang Li, Zheng Wang, Baobao Zhao, Han Zhang, Dexiang Fan, Huiming Ma, Yong Zhang, Yongsheng Wang
IF：
2.2000
Publish_to：
ANIMAL REPRODUCTION SCIENCE
PMID：
37729849
Long noncoding RNA XIST knockdown relieves the injury of microglia cells after spinal cord injury by sponging miR-219-5p
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Author：
Xueren Zhong, Yongzheng Bao, Qiang Wu, Xinhua Xi, Wengang Zhu, Sanmei Chen, Junjian Liao
IF：
2.1990
Publish_to：
Open Medicine
PMID：
34414282
Effects of Altitude and Duration of Differing Levels of Hypoxic Exposure on Hypoxia-Inducible Factor-1α in Rat Tissues
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Author：
Xiao-lin Li, Wei-gang Wang, Mao-xing Li, Tian-long Liu, Xiu-yu Tian, Lan Wu
IF：
2.1830
Publish_to：
HIGH ALTITUDE MEDICINE & BIOLOGY
PMID：
35708531
Circ_0004104 participates in the regulation of ox-LDL-induced endothelial cells injury via miR-942-5p/ROCK2 axis
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Author：
Zhang Yuanyuan, Wang Shaojun, Guo Sicong, Zhang Xinzhong, Yang Chuan, Su Guangsheng, Wan Jiye
IF：
2.1740
Publish_to：
BMC Cardiovascular Disorders
PMID：
36460954
MiR-21-5p inhibition attenuates Warburg effect and stemness maintenance in osteosarcoma cells via inactivation of Wnt/β-catenin signaling
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Author：
Ziyan Wu, Zhong Zhou, Weiguo Zhang, Yi Yu
IF：
2.1490
Publish_to：
ACTA BIOCHIMICA POLONICA
PMID：
34694765
Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP
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Author：
Miao Liu, Shuling Li, Chun Ma, Xinna Wang, Yu Shuang, Haining Lin, Zhiying Guan, Lihua Yang
IF：
2.1000
Publish_to：
Molecular Medicine Reports
PMID：
33313948
Upregulated miR-125b mitigates inflammation, astrocyte activation, and dysfunction of spinal cord injury by inactivating the MAPK pathway
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Author：
Xianhu Yue, Mingyong Gu, Tanghong Jia
IF：
2.0000
Publish_to：
HISTOLOGY AND HISTOPATHOLOGY
PMID：
37166139
Effect of HDAC9-induced deacetylation of glycolysis-related GAPDH lysine 219 on rotavirus replication in rotavirus-infected Caco-2 cells
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Author：
Song Lijun, Zhong Peicheng, Yu Runyu, Yuan Yue, Zhou Yujing, Qian Yupei, Yang Siyan, Yi Haosen, Yang Zhiyan, Zhao Wenchang
IF：
1.9000
Publish_to：
VIRUS GENES
PMID：
39302542
CircARL8B Contributes to the Development of Breast Cancer Via Regulating miR-653-5p/HMGA2 Axis
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Author：
Wu Hansheng, Xu Jingyun, Gong Guoliang, Zhang Yuanxin, Wu Shenggui
IF：
1.8900
Publish_to：
BIOCHEMICAL GENETICS
PMID：
34050452
Transcription Factor E2F1 Regulates the Expression of ADRB2
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Author：
Juan Du, Feifei Rui, Zhongfen Hao, Yun Hang, Jin Shu
IF：
1.8000
Publish_to：
International Journal of Analytical Chemistry
PMID：
37128280
Sophora flavescens alcohol extract ameliorates insomnia and promotes PI3K/AKT/BDNF signaling transduction in insomnia model rats
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Author：
Wu Yanyan, Yao Chenhang, Zhang Lan, Wu Guoqing
IF：
1.7000
Publish_to：
NEUROREPORT
PMID：
38407863
NADPH oxidase 2 plays a protective role in experimental Aspergillus fumigatus keratitis in mice through killing fungi and limiting the degree of inflammation
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Author：
Qiang Xu, Qian Wang, Li-Ting Hu, Jing Lin, Nan Jiang, Xu-Dong Peng, Cui Li, Gui-Qiu Zhao
IF：
1.6450
Publish_to：
International Journal of Ophthalmology
PMID：
35919314
Insight into the thrombolytic ability of an extracellular fibrinolytic enzyme from Bacillus amyloliquefaciens GXU-1 isolated from Sipunculus nudus
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Author：
Hongrui Jiang, Ruiyuan Shi, Xiaomei Li, Jiale Tang, Douyong Min
IF：
1.6000
Publish_to：
PROTEIN EXPRESSION AND PURIFICATION
PMID：
37709210
Exosomes Promote Atherosclerosis Progression by Regulating Circ_100696/miR-503-5p/PAPPA Axis-Mediated Vascular Smooth Muscle Cells Proliferation and Migration
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Author：
Jing Liu, Xiangyang Zhang, Zhaoxia Yu, Tieliang Zhang
IF：
1.5000
Publish_to：
International Heart Journal
PMID：
37778995
Screening, expression and anti-tumor functional identification of anti-LAG-3 nanobodies
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Author：
Dan Jiang, Rui Chen, Liyan Wang, Guangxian Xu
IF：
1.4000
Publish_to：
PROTEIN EXPRESSION AND PURIFICATION
PMID：
38851552
Circ_WWC3 overexpression decelerates the progression of osteosarcoma by regulating miR-421/PDE7B axis
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Author：
Sihai Liu, Jing Zhang, Ting Zheng, Xiongneng Mou, Wenwei Xin
IF：
0.9380
Publish_to：
Open Life Sciences
PMID：
33817314
技术问答
（6）
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我的目的蛋白分子量是11.7 该怎么跑这个指标 每次都跑不出来 其他条件都是好的?2023-10-27 18:07:37
您好，可以提高分离胶的浓度，如果还是跑不出来，可以换用P1320这种专用于小分子蛋白及多肽电泳的试剂盒。
蛋白分子量为275KD，PAGE胶浓度选多少合适呢?2023-10-16 09:50:13
您好，分子量较大的蛋白可以尝试跑低浓度的胶，可以用6%的跑一下。
分离最高蛋白分子量是多少,可以分离200kD以上吗?2023-10-13 10:32:21
您好，目前这边跑过的蛋白常规广谱彩虹marker一般最大到245KD，分子量大的需要使用更低浓度的胶，没有做过更大的蛋白了。
我想问下SDS-PAGE的电流和电压的条件，我的5-245的marker25kd以下的条带跑不出来，并且胶的下面是染不上色，不知道什么原因?2023-05-09 09:41:38
您好，一般电泳程序建议80V，20min;120V，70-80min。
你好，这个可以跑DNA分子吗?2023-04-28 09:26:09
您好，可以的，适用于蛋白、DNA和RNA。