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Anti-BAX Polyclonal Antibody

Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using BAX at dilution of 1:100 (x100 lens,x200 lens).


相关信息

英文名称 Anti-BAX Polyclonal Antibody
宿主 Rabbit
别名 Bcl2-L-4;Bax-protein;BAX_HUMAN;BAXA
稀释比例 IHC 1:50-200.
蛋白分子量 21kDa
Gene ID 581
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human BAX
性状 液体
Public Immunogen Range A synthetic peptide of human BAX
Swiss Prot Q07812
亚细胞定位 Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein
克隆类型 Polyclonal Antibody
背景资料 Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.7
应用    IHC
交叉反应    Human
规格    50ul    100ul

注意:
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货号:K106624P
品牌:Solarbio
规格:

为科研服务、为生命尽责