Anti-BAX Polyclonal Antibody_一抗_抗体_索莱宝-专业生化试剂网上商城

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英文名称	Anti-BAX Polyclonal Antibody
宿主	Rabbit
别名	Bcl2-L-4;Bax-protein;BAX_HUMAN;BAXA
稀释比例	IHC 1:50-200.
蛋白分子量	21kDa
Gene ID	581
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human BAX
性状	液体
Public Immunogen Range	A synthetic peptide of human BAX
Swiss Prot	Q07812
亚细胞定位	Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein
克隆类型	Polyclonal Antibody
背景资料	Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.7
应用	IHC
交叉反应	Human
规格	50ul 100ul

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