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产品简介
| 英文名称 | Percoll |
| 中文名称 | Percoll细胞分离液 |
| CAS | No.65455-52-9 |
| 外观(性状) | 淡黄色液体 |
| 储存条件 | 2-8℃，4 years |
| 注意事项 | 沉淀是硅胶体聚集，不影响使用。 |
| 规格 | 100ml 1L |
| 单位 | 瓶 |
密度：1.13g/ml
适合分离细胞，亚细胞成分和大病毒(>70S)，渗透压均匀，粘度低，可调至生理离子强度和pH，分离条件温和，对细胞无毒性，可以灭菌消毒。
Percoll分离液是一种经过聚乙烯吡咯烷酮处理过的硅胶颗粒，经过高速离心后可形成连续密度梯度，由于Percoll扩散常数低，所形成的梯度十分稳定。Percoll分离液采用预先形成的密度梯度时可在低离心力(200～1000g)于数分至数十分钟内达到满意的细胞分离结果。此外，Percoll分离液不穿透生物膜，对细胞无毒害，因此广泛用于分离细胞、亚细胞成分、细菌及病毒，还可将受损细胞及其碎片与完好的活细胞分离。Percoll常用于分离和传话植物原生质体、核、叶绿体、和线粒体。
Percoll分离液的配置与使用
1、不同浓度(密度)Percoll分离液的制备: 先用9份Percoll分离液与1份8.5％ NaCl混合达到生理性渗透压，然后用生理溶液(0.85％ NaCl)稀释到所需浓度。
2、不连续密度梯度Percoll层的制备: 先将试管壁用牛血清湿润，除去多余血清，这种预处理可使逐层叠加的Percoll液平稳沿管壁流下，使形成满意的界面。在制备过程中一般用长针头注射器从高密度向低密度逐层放置，有时相邻两层Percoll比重相差不大时，可将Percoll液放入注射器中，小针头斜面紧贴管壁，任其自然慢慢流下。
3、装样：样品体积和细胞浓度根据不同细胞而异，一般加样体积不宜过大，细胞浓度也不可过高，否则会影响细胞的分离和回收。
4、离心：一般采用离心力为400g，时间20～25min。由于多层Percoll之间密度差别不大，因此离心机加速、降速时要慢，要平稳。
5、取样：当所要分离的细胞绝大部分在两层的界面时，可逐层去除Percoll液后收集界面部位的细胞;有时大部分细胞位于Percoll层中,则需要逐层收集。收获含有Percoll液的细胞经2次洗涤后可供培养或检测用。
Percoll细胞分离液的优点
Percoll渗透性低、不穿透细胞、密度高、无毒害，是目前较理想的介质。Percoll密度梯度离心已被多次成功地用于动物细胞及其细胞器的分离，纯化了包括人血液细胞、骨髓细胞、红血球细胞、白血球细胞、淋巴细胞、肝细胞等在内的十余种动物细胞。
Percoll细胞分离液注意事项：
1、Percoll细胞分离液在储存及孵育过程中避免将试剂保留在强光中。
2、试剂瓶盖需盖紧，防止蒸发和污染。
北京索莱宝科技有限公司生产销售Percoll细胞分离液货号为P8370。适合分离细胞、亚细胞成分和大病毒（＞70s），渗透压均匀，粘度低，可调至生理离子强度和pH，分离条件温和，对细胞无毒性，可以灭菌消毒。密度为1.13g/ml。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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JOURNAL OF CONTROLLED RELEASE
PMID：
33965503
Activating cGAS–STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis
点击查看 >>
Author：
Ding Rui, Li Haiyan, Liu Yaqi, Ou Weiyang, Zhang Xifang, Chai Huihui, Huang Xiaofei, Yang Weijie, Wang Qiujing
IF：
9.5870
Publish_to：
Journal of Neuroinflammation
PMID：
35689216
Rationally Designed Self-Assembling Nanovaccines Elicit Robust Mucosal and Systemic Immunity against Rhabdovirus
点击查看 >>
Author：
Chen Zhang, Zhao Zhao, Yi-Jun Jia, Peng-Qi Zhang, Yun Sun, Yong-Can Zhou, Gao-Xue Wang, Bin Zhu
IF：
9.5000
Publish_to：
ACS Applied Materials & Interfaces
PMID：
38055273
JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism
点击查看 >>
Author：
Wei Huang, Bi-Ou Wang, Yun-Feng Hou, Yi Fu, Si-Jia Cui, Jing-Han Zhu, Xin-Yu Zhan, Rong-Kun Li, Wei Tang, Ji-Chao Wu, Zi-Ying Wang, Mei Wang, Xiao-Jie Wang, Yan Zhang, Min Liu, Yu-Sheng Xie, Yu Sun, Fan Yi
IF：
9.4840
Publish_to：
JCI Insight
PMID：
35708906
OsFBN7–OsKAS I module promotes formation of plastoglobules clusters in rice chloroplasts
点击查看 >>
Author：
Jiajia Li, Dongyan Kong, Ting Song, Zhenzhu Hu, Qiang Li, Benze Xiao, Felix Kessler, Zhengfeng Zhang, Guosheng Xie
IF：
9.4000
Publish_to：
NEW PHYTOLOGIST
PMID：
37366020
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy
点击查看 >>
Author：
Yang Lixuan, Ao Yutian, Li Yannan, Dai Baoan, Li Jingchun, Duan Wenzhe, Gao Wei, Zhao Zhonghui, Han Zhenyun, Guo Rongjuan
IF：
9.3000
Publish_to：
Journal of Neuroinflammation
PMID：
36765376
METTL3/METTL14 Transactivation and m6A-Dependent TGF-β1 Translation in Activated Kupffer Cells
点击查看 >>
Author：
Yue Feng, Haibo Dong, Bo Sun, Yun Hu, Yang Yang, Yimin Jia, Longfei Jia, Xiang Zhong, Ruqian Zhao
IF：
9.2250
Publish_to：
Cellular and Molecular Gastroenterology and Hepatology
PMID：
33992834
Bacteroides uniformis-induced perturbations in colonic microbiota and bile acid levels inhibit TH17 differentiation and ameliorate colitis developments
点击查看 >>
Author：
Yan YiTing, Lei Yu, Qu Ying, Fan Zhen, Zhang Ting, Xu Yangbin, Du Qian, Brugger Daniel, Chen Yulin, Zhang Ke, Zhang Enping
IF：
9.2000
Publish_to：
npj Biofilms and Microbiomes
PMID：
37580334
Faecalibacterium prausnitzii-derived extracellular vesicles alleviate chronic colitis-related intestinal fibrosis by macrophage metabolic reprogramming
点击查看 >>
Author：
Ying Wang, Linjie Li, Shuze Chen, Zonglin Yu, Xuefeng Gao, Xiaojie Peng, Qiujuan Ye, Zitong Li, Weihao Tan, Ye Chen
IF：
9.1000
Publish_to：
PHARMACOLOGICAL RESEARCH
PMID：
38945379
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance
点击查看 >>
Author：
Ye Chen, Xiao Wu, Jing Zhang, Guopin Pan, Xiaoyun Wang, Xiaosun Guo, Jianli Wang, Xiaopei Cui, Haiqing Gao, Mei Cheng, Jingwen Yang, Cheng Zhang, Fan Jiang
IF：
9.0710
Publish_to：
EMBO REPORTS
PMID：
34994492
No Genus-Specific Gene Is Essential for the Replication of Fowl Adenovirus 4 in Chicken LMH Cells
点击查看 >>
Author：
Xinglong Liu, Xiaohui Zou, Wenfeng Zhang, Xiaojuan Guo, Min Wang, Yingtao Lv, Tao Hung, Zhuozhuang Lu
IF：
9.0430
Publish_to：
Microbiology Spectrum
PMID：
35638786
Expressing Phosphate Transporter PvPht2;1 Enhances P Transport to the Chloroplasts and Increases Arsenic Tolerance in Arabidopsis thaliana
点击查看 >>
Author：
Huayuan Feng, Xinyuan Li, Dan Sun, Yanshan Chen, Guohua Xu, Yue Cao, Lena Q. Ma
IF：
9.0280
Publish_to：
ENVIRONMENTAL SCIENCE & TECHNOLOGY
PMID：
33497189
Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11–Mediated IL18 in the Gut Epithelial Cells
点击查看 >>
Author：
Qianjin Zhang, Xiaomin Su, Chunze Zhang, Wei Chen, Ya Wang, Xiaorong Yang, Dan Liu, Yuan Zhang, Rongcun Yang
IF：
8.7970
Publish_to：
Cellular and Molecular Gastroenterology and Hepatology
PMID：
36436756
CCDC134 facilitates T cell activation through the regulation of early T cell receptor signaling
点击查看 >>
Author：
Tianzhuo Zhang, Qianwen Shi, Huining Gu, Biaoyi Yu, Sha Yin, Qing Ge, Xiaoning Mo, Xiaofeng Liu, Jing Huang
IF：
8.7860
Publish_to：
Frontiers in Immunology
PMID：
37234153
Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis
点击查看 >>
Author：
Ruomei Cheng, Xiaopeng Tang, Qiyu Zhao, Yuming Wang, Wenlin Chen, Gan Wang, Chenxi Wang, James Mwangi, Qiumin Lu, Dawit Adisu Tadese, Xudong Zhao, Caiwen Ou, Ren Lai
IF：
8.5000
Publish_to：
Research
PMID：
39810853
Metabolic characteristics and markers in viable but nonculturable state of Pseudomonas aeruginosa induced by chlorine stress
点击查看 >>
Author：
Zheng Qi, Chunguang Liu
IF：
8.4310
Publish_to：
ENVIRONMENTAL RESEARCH
PMID：
35987374
STING Agonist Delivered by Neutrophil Membrane-Coated Gold Nanoparticles Exerts Synergistic Tumor Inhibition with Radiotherapy
点击查看 >>
Author：
Dehua Lu, Wenhua Li, Jingyun Tan, Ying Li, Wei Mao, Yuanyuan Zheng, Muwen Yang, Jin Wang, Weihu Wang, Shubin Wang, Jing Gao, Yajie Liu
IF：
8.3000
Publish_to：
ACS Applied Materials & Interfaces
PMID：
39316508
Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching
点击查看 >>
Author：
Shen Shi-chun, Xu Jie, Cheng Cheng, Xiang Xin-jian, Hong Bao-yu, Zhang Meng, Gong Chen, Ma Li-kun
IF：
8.2000
Publish_to：
ACTA PHARMACOLOGICA SINICA
PMID：
38225394
Biotransformation of bis(2-chloroethyl)2-chloroethylphosphphonate, and its effects on metabolism of lipid molecules in primary mouse hepatocytes
点击查看 >>
Author：
Qi Zhang, Jianan Huang, Pingping Kang, Guanyong Su
IF：
8.1000
Publish_to：
CHEMOSPHERE
PMID：
39938318
Discovery of DNA-Targeting HDAC Inhibitors with Potent Antitumor Efficacy In Vivo That Trigger Antitumor Immunity
点击查看 >>
Author：
Chen Chen, Xue Li, Huajun Zhao, Meng Liu, Jintong Du, Jian Zhang, Xinying Yang, Xuben Hou, Hao Fang
IF：
8.0390
Publish_to：
JOURNAL OF MEDICINAL CHEMISTRY
PMID：
35152694
Extracellular vesicles of Bacteroides uniformis induce M1 macrophage polarization and aggravate gut inflammation during weaning
点击查看 >>
Author：
Wenjie Tang, Zhixiang Ni, Yusen Wei, Kangwei Hou, Teresa G. Valencak, Haifeng Wang
IF：
8.0000
Publish_to：
Mucosal Immunology
PMID：
38777177
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis
点击查看 >>
Author：
Yannan Li, Junnan Li, Lixuan Yang, Feifei Ren, Kaiqiang Dong, Zhonghui Zhao, Wenzhe Duan, Wei Wei, Rongjuan Guo
IF：
7.9000
Publish_to：
PHYTOMEDICINE
PMID：
37722244
Neutrophil mediated postoperative photoimmunotherapy against melanoma skin cancer
点击查看 >>
Author：
Yunyun Wu, Xiaoqing Han, Runxiao Zheng, Hongda Cheng, Jiao Yan, Xiaqing Wu, Yaqing Hu, Bing Li, Zhenxin Wang, Xi Li, Haiyuan Zhang
IF：
7.7900
Publish_to：
Nanoscale
PMID：
34533171
Enhancing anti-tumor efficacy and immune memory by combining 3p-GPC-3 siRNA treatment with PD-1 blockade in hepatocellular carcinoma
点击查看 >>
Author：
Liwei Shao, Xin Yu, Qiuju Han, Xinke Zhang, Nan Lu, Cai Zhang
IF：
7.7230
Publish_to：
OncoImmunology
PMID：
36524206
Identification and functional characterization of a novel cystatin in amphioxus, ancient origin of vertebrate type-2 cystatin homologues
点击查看 >>
Author：
Tianren Wang, Jingru Gao, Jinghan Xu, Yuxiang Hong, Ronghuan Du, Xian Zheng, Peng Wang
IF：
7.7000
Publish_to：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
PMID：
39097064
Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway
点击查看 >>
Author：
Junqiang Zhang, Yuan Fang, Dongdong Tang, Xingyu Xu, Xiaoqian Zhu, Shusheng Wu, Hui Yu, Huiru Cheng, Ting Luo, Qunshan Shen, Yang Gao, Cong Ma, Yajing Liu, Zhaolian Wei, Xiaoyu Chen, Fangbiao Tao, Xiaojin He, Yunxia Cao
IF：
7.6660
Publish_to：
Cells
PMID：
35626727
Inhibition of tumor recurrence and metastasis via a surgical tumor-derived personalized hydrogel vaccine
点击查看 >>
Author：
Yi Lu, Chenghu Wu, Yanyan Yang, Xiangzhong Chen, Feihang Ge, Jilong Wang, Junjie Deng
IF：
7.5900
Publish_to：
Biomaterials Science
PMID：
35112690
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL−33/ST2 Signaling
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Author：
Deng Fan, Hu Jing-Juan, Yang Xiao, Sun Qi-Shun, Lin Ze-Bin, Zhao Bing-Cheng, Yao Zhi-Wen, Luo Si-Dan, Chen Ze-Ling, Liu Ying, Yan Zheng-Zheng, Li Cai, Liu Wei-Feng, Liu Ke-Xuan
IF：
7.5610
Publish_to：
Frontiers in Immunology
PMID：
34650552
Engineering M2 type macrophage-derived exosomes for autoimmune hepatitis immunotherapy via loading siRIPK3
点击查看 >>
Author：
Lu Zhang, Man Liu, Qiu Sun, Shuqin Cheng, Yirong Chi, Jie Zhang, Bangmao Wang, Lu Zhou, Jingwen Zhao
IF：
7.5000
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
38244330
Dominant negative TGF-β receptor type II in T lymphocytes promotes anti-tumor immunity by modulating T cell subsets and enhancing CTL responses
点击查看 >>
Author：
Hao Li, Yanling Guan, Chenchen Han, Yu Zhang, Yizhao Chen, Liping Jiang, Pingping Zhang, Xiu Chen, Wei Wei, Yang Ma
IF：
7.4190
Publish_to：
BIOMEDICINE & PHARMACOTHERAPY
PMID：
35228061
Characterization of early myocardial inflammation in ischemia-reperfusion injury
点击查看 >>
Author：
Qihong Wu, Rong Xu, Kun Zhang, Ran Sun, Mengxi Yang, Kuan Li, Hanrui Liu, Yiyuan Xue, Huayan Xu, Yingkun Guo
IF：
7.3000
Publish_to：
Frontiers in Immunology
PMID：
36814859
The dephosphorylation of FADD at S191 induces an excessive expansion of TCRαβ+ IELs in the intestinal mucosa
点击查看 >>
Author：
Xuerui Zhang, Banghui Zhu, Lin Li, Jiahong Xu, Yuheng Han, Jing Zhang, Zichun Hua
IF：
7.2150
Publish_to：
IMMUNOLOGY
PMID：
35753028
Stimulation of Liver Fibrosis by N2 Neutrophils in Wilson’s Disease
点击查看 >>
Author：
Xiaoxiao Mi, Yu Song, Chaohua Deng, Jian Yan, Zhihui Li, Yingniang Li, Jun Zheng, Wenjun Yang, Ling Gong, Junping Shi
IF：
7.2000
Publish_to：
Cellular and Molecular Gastroenterology and Hepatology
PMID：
37406734
Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes
点击查看 >>
Author：
Lumei Wang, Pimiao Zheng, Yukun Cui, Zhuanglong Zhang, Kaimin Song, Yongxia Liu, Jianzhu Liu
IF：
7.1290
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
36423368
Acute high-altitude hypoxia exposure causes neurological deficits via formaldehyde accumulation
点击查看 >>
Author：
Xiaoyin Wang, Haochen Sun, Lili Cui, Xian Wang, Changhong Ren, Zhiqian Tong, Xunming Ji
IF：
7.0350
Publish_to：
CNS Neuroscience & Therapeutics
PMID：
35582960
Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis
点击查看 >>
Author：
许恒
IF：
7.0000
Publish_to：
PMID：
34421916
Deficiency of transmembrane AMPA receptor regulatory protein γ-8 leads to attention-deficit hyperactivity disorder-like behavior in mice
点击查看 >>
Author：
Wan-Jun Bai, Xing-Guang Luo, Bao-Hua Jin, Kang-Sheng Zhu, Wen-Yan Guo, Xiao-Que Zhu, Xia Qin, Zu-Xiao Yang, Jiao-Jiao Zhao, Si-Ruan Chen, Ri Wang, Jie Hao, Fei Wang, Yun Stone Shi, De-Zhi Kong, Wei Zhang
IF：
6.9750
Publish_to：
ZOOLOGICAL RESEARCH
PMID：
36031768
Periploca forrestii Schltr. ameliorate liver injury caused by fluorosis in rat
点击查看 >>
Author：
Wei-yu Guo, Ding-yan Lu, Zhi-zhong Guan, Lin Zheng, Shuai-shuai Chen, Ting Liu
IF：
6.8000
Publish_to：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
PMID：
38113798
Xuanfei Baidu Decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFNγ/STAT1/STAT3 axis
点击查看 >>
Author：
Mengjie Jia, Yiman Liu, Jia Liu, Junyu Meng, Jiazhen Cao, Lin Miao, Han Zhang, Yan Zhu, Mengmeng Sun, Jian Yang
IF：
6.7000
Publish_to：
PHYTOMEDICINE
PMID：
39312850
Inducing Non-genetically Modified Induced Embryonic Sertoli Cells Derived From Embryonic Stem Cells With Recombinant Protein Factors
点击查看 >>
Author：
Xu Chenze, Mohsin Ali, Luo Yanxia, Xie Lili, Peng Yan, Wang Qizheng, Ahmed Waqas, Hang Haifeng, Zhuang Yingping, Guo Meijin
IF：
6.6840
Publish_to：
Frontiers in Cell and Developmental Biology
PMID：
33585437
Metabolic Reprogramming of CD4+ T Cells by Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuates Autoimmune Hepatitis Through Mitochondrial Protein Transfer
点击查看 >>
Author：
Mengyi Shen, Leyu Zhou, Xiaoli Fan, Ruiqi Wu, Shuyun Liu, Qiaoyu Deng, Yanyi Zheng, Jingping Liu, Li Yang
IF：
6.6000
Publish_to：
International Journal of Nanomedicine
PMID：
39345912
Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota
点击查看 >>
Author：
He Ke-Jie, Dong Jia-Hui, Ouyang Xiao-Mei, Huo Ya-Ni, Cheng Xiao-Shen, Lin Ying, Li Yue, Gong Guoyu, Liu Jingjing, Ren Jian-Lin, Guleng Bayasi
IF：
6.5900
Publish_to：
Frontiers in Nutrition
PMID：
36034889
The dysfunction of CD8+ T cells triggered by endometriotic stromal cells promotes the immune survival of endometriosis
点击查看 >>
Author：
Zhi-Xiong Huang, Dian-Chao Lin, Hua-Ying Zhang, Meng-Jie Yang, Jia-Hao Chen, Xin-Yu Ding, Song-Juan Dai, Yi-Huang Hong, Gui-Shuang Liang, Qi-Yuan Li, Qiong-Hua Chen
IF：
6.4000
Publish_to：
IMMUNOLOGY
PMID：
38544333
SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis
点击查看 >>
Author：
Teng Xiu, Mou Da-Chao, Li Hui-Fang, Jiao Ling, Wu Sha-Sha, Pi Jin-Kui, Wang Yan, Zhu Meng-Li, Tang Meng, Liu Yi
IF：
6.3760
Publish_to：
MOLECULAR MEDICINE
PMID：
36401167
Construction of a competing endogenous RNA network to identify drug targets against polycystic ovary syndrome
点击查看 >>
Author：
Wu Tong, Gao Yue-Yue, Tang Xia-Nan, Li Yan, Dai Jun, Zhou Su, Wu Meng, Zhang Jin-Jin, Wang Shi-Xuan
IF：
6.3530
Publish_to：
HUMAN REPRODUCTION
PMID：
36223608
IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation
点击查看 >>
Author：
崔济开
IF：
6.3040
Publish_to：
PMID：
34006836
The AMPK and AKT/GSK3β pathways are involved in recombinant proteins fibroblast growth factor 1 (rFGF1 and rFGF1a) improving glycolipid metabolism in rainbow trout (Oncorhynchus mykiss) fed a high carbohydrate diet
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Author：
Huixia Yu, Shuo Geng, Shuai Li, Yingwei Wang, Xin Ren, Debin Zhong, Haolin Mo, Mingxing Yao, Jiajia Yu, Yang Li, Lixin Wang
IF：
6.3000
Publish_to：
Animal Nutrition
PMID：
38444689
Neuroprotective Effects of the Pannexin-1 Channel Inhibitor: Probenecid on Spinal Cord Injury in Rats
点击查看 >>
Author：
Qi Qi, Wang Xiao-Xuan, Li Jing-Lu, Chen Yu-Qing, Chang Jian-Rong, Xi Jin, Lü He-Zuo, Zhang Yu-Xin
IF：
6.2610
Publish_to：
Frontiers in Molecular Neuroscience
PMID：
35663270
Vasoactive Intestinal Peptide (VIP) Protects Nile Tilapia (Oreochromis niloticus) against Streptococcus agalatiae Infection
点击查看 >>
Author：
Zhiqiang Zhang, Qi Li, Yongxiong Huang, Zhou Xu, Xinjin Chen, Baijian Jiang, Yu Huang, Jichang Jian
IF：
6.2080
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
36499231
NLRP6 deficiency suppresses colorectal cancer liver metastasis growth by modulating M-MDSC-induced immunosuppressive microenvironment
点击查看 >>
Author：
Liangzheng Chang, Lei Xu, Yuying Tian, Zherui Liu, Meiru Song, Shuang Li, Xinfeng Zhang, Yue Chen, Qiuyao Hao, Yinying Lu, Yunhuan Zhen
IF：
6.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
38278335
Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke
点击查看 >>
Author：
Jing Liu, Danmin Shen, Chao Wei, Weihua Wu, Zhaoli Luo, Liye Hu, Zhongnan Xiao, Tingting Hu, Qingyu Sun, Xiaotong Wang, Yumeng Ding, Meng Liu, Miaoyi Pang, Kaiyuan Gai, Yiran Ma, Yichen Tian, Yan Yu, Peipei Wang, Yun Guan, Meng Xu, Fei Yang, Qian Li
IF：
6.1070
Publish_to：
iScience
PMID：
36465125
Limonin alleviates high-fat diet-induced dyslipidemia by regulating intestinal barrier via microbiota-related ILC3-IL22-IL22R pathway
点击查看 >>
Author：
Wangling Wu, Yingying Pan, Tianyan Zheng, Haoyi Sun, Xia Li, Haiyan Zhu, Zheng Wang, Xin Zhou
IF：
6.1000
Publish_to：
Food & Function
PMID：
38375746
Grim-19 deficiency promotes decidual macrophage autophagy in recurrent spontaneous abortion
点击查看 >>
Author：
Yang Yang, Liu Haoran, Zhao Yue, Geng Chen, Chao Lan, Hao Aijun
IF：
6.0550
Publish_to：
Frontiers in Endocrinology
PMID：
36387896
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages
点击查看 >>
Author：
Xiaoyan Qin, Dingheng Hu, Qi Li, Shiyi Zhang, Zheng Qin, Liangxu Wang, Rui Liao, Zhongjun Wu, Yanyao Liu
IF：
6.0000
Publish_to：
MOLECULAR MEDICINE
PMID：
40087552
Gamma-type immunoglobulin enhances phagocytosis of amyloid-beta fibrils by microglia
点击查看 >>
Author：
Zhou Tian, Zhong Yue, Yu Shoujun, Sun Ruibing, Zhang Zhenwei, Du Xiaoyan, Lee Simon Ming-Yuen, Chen Zhitong, Tian Weiming, Lai Yuxiao, Song Bing, Zheng Yiming, Xu Zhen
IF：
5.9000
Publish_to：
Neural Regeneration Research
PMID：
39104171
Yes-associated protein promotes the proliferation and differentiation of liver progenitor cells during liver fibrosis
点击查看 >>
Author：
Zhenyang Shen, Weiming Dai, Yuecheng Guo, Junjun Wang, Bo Shen, Binghang Li, Lungen Lu, Xiaobo Cai
IF：
5.8340
Publish_to：
FASEB JOURNAL
PMID：
37073611
A new proposed semi-quantitative method for the organic additives analysis in traditional lime mortar
点击查看 >>
Author：
Jinxin Li, Huimin Sun, Meiling Fu, Zeyuan Zheng, Chunlan Xu, Kunao Yang, Yankuo Liu, Zuodong Xuan, Yang Bai, Jianzhong Zheng, Yue Zhao, Zhiyuan Shi, Chen Shao
IF：
5.8000
Publish_to：
iScience
PMID：
37404377
Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration
点击查看 >>
Author：
Liu, Xiaoling, Zu, Er, Chang, Xinyu, Ma, Xiaowei, Wang, Ziqi, Song, Xintong, Li, Xiangru, Yu, Qing, Kamei, Ken-ichiro, Hayashi, Toshihiko, Mizuno, Kazunori, Hattori, Shunji, Fujisaki, Hitomi, Ikejima, Takashi, Wang, Dan Ohtan
IF：
5.7580
Publish_to：
Disease Models & Mechanisms
PMID：
34821368
Osj10gBTF3-Mediated Import of Chloroplast Protein Is Essential for Pollen Development in Rice
点击查看 >>
Author：
Liu Xue-jiao, Sun Jiaqi, Huang Yuqing, Li Chao, Zheng Peng, Yuan Yue, Chen Hao, Jan Mehmood, Zheng Huanquan, Du Hao, Tu Jumin
IF：
5.7540
Publish_to：
Frontiers in Plant Science
PMID：
34421965
Inhibition of interleukin-6 trans-signaling improves survival and prevents cognitive impairment in a mouse model of sepsis
点击查看 >>
Author：
Sufang Jiang, Dandan Shi, Long Bai, Tianfu Niu, Rongtian Kang, Ya Liu
IF：
5.7140
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37058750
Autoantibody repertoire profiling in tissue and blood identifies colorectal cancer-specific biomarkers
点击查看 >>
Author：
Pei-Fen Zhang, Ziyi Wu, Ting Zhou, Da-Wei Yang, Quan-Kai Mu, Wen-Bin Zhang, Long Yu, Shao-Dan Zhang, Ye-Zhu Hu, Jianbing Mu, Wei-Hua Jia
IF：
5.7000
Publish_to：
CANCER SCIENCE
PMID：
37985391
EphA4/EphrinB2 signaling mediates pericyte-induced transient glia limitans formation as a secondary protective barrier after subarachnoid hemorrhage in mice
点击查看 >>
Author：
Jiru Zhou, Peiwen Guo, Mingxu Duan, Junhan Li, Xufang Ru, Lin Li, Zongduo Guo, John H. Zhang, Hua Feng, Yujie Chen, Xiaochuan Sun
IF：
5.6200
Publish_to：
EXPERIMENTAL NEUROLOGY
PMID：
36493862
Human placental mesenchymal stromal cells modulate IFN-污 and IL-10 secretion by CD4+T cells via CD73, and alleviate intestinal damage in mice with graft-versus-host disease
点击查看 >>
Author：
Jiashen Zhang, Yaxuan Zhao, Hengchao Zhang, Kaiyue Han, Junjie Ma, Yanlian Xiong, Guoyan Wang, Xiying Luan
IF：
5.6000
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
37657243
Mannose modified targeted immersion vaccine delivery system improves protective immunity against Infectious spleen and kidney necrosis virus in mandarin fish (Siniperca chuatsi)
点击查看 >>
Author：
Zhao Zhao, Qiang Meng, Tian-Zi Sun, Bin Zhu
IF：
5.5000
Publish_to：
VACCINE
PMID：
38519342
2,3,5,4′- tetrahydroxystilbene-2-O-β-D- glucopyranoside (TSG)-Driven immune response in the hepatotoxicity of Polygonum multiflorum
点击查看 >>
Author：
Wenhui Liu, Xiangchang Zeng, Xinfeng Wang, Yuwei Hu, Lulu Chen, Naixiang Luo, Dongsheng Ouyang, Tai Rao
IF：
5.4000
Publish_to：
JOURNAL OF ETHNOPHARMACOLOGY
PMID：
38369066
STZ-induced diabetes exacerbates neurons ferroptosis after ischemic stroke by upregulating LCN2 in neutrophils
点击查看 >>
Author：
Huan Wang, Zhao Wang, Yuxiao Gao, Jingjing Wang, Yujia Yuan, Cong Zhang, Xiangjian Zhang
IF：
5.3000
Publish_to：
EXPERIMENTAL NEUROLOGY
PMID：
38670252
HMGB1 from Astrocytes Promotes EAE by Influencing the Immune Cell Infiltration-Associated Functions of BMECs in Mice
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Author：
Shi Junyu, Xiao Yifan, Zhang Na, Jiao Mengya, Tang Xuhuan, Dai Chan, Wang Chenchen, Xu Yong, Tan Zheng, Gong Feili, Zheng Fang
IF：
5.2710
Publish_to：
Neuroscience Bulletin
PMID：
35697993
ARRB1 suppresses the activation of hepatic macrophages via modulating endoplasmic reticulum stress in lipopolysaccharide-induced acute liver injury
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Author：
Lei Yiming, Wan Sizhe, Liu Huiling, Zhou Haoxiong, Chen Lingjun, Yang Yidong, Wu Bin
IF：
5.2410
Publish_to：
Cell Death Discovery
PMID：
34455423
Sleeve gastrectomy decreases high-fat diet induced colonic pro-inflammatory status through the gut microbiota alterations
点击查看 >>
Author：
Chong Cao, Xiaozhuo Tan, Hai Yan, Qiwei Shen, Rong Hua, Yikai Shao, Qiyuan Yao
IF：
5.2000
Publish_to：
Frontiers in Endocrinology
PMID：
37008903
The lactate receptor GPR81 mediates hepatic lipid metabolism and the therapeutic effect of metformin on experimental NAFLDs
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Author：
Guanglu Wu, Yufeng Dai, Yongheng Yan, Xu Zheng, Hao Zhang, Haitao Li, Wei Chen
IF：
5.1950
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
35430208
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure
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Author：
Lei Wu, Shuang Li, Chao Li, Bin He, Linyi Lv, Jia Wang, Jierui Wang, Weixuan Wang, Yanshu Zhang
IF：
5.1940
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
34742682
CRP Involved in Nile Tilapia (Oreochromis niloticus) against Bacterial Infection
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Author：
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Jia Cai, Yu Huang, Jichang Jian
IF：
5.1680
Publish_to：
Biology-Basel
PMID：
36009776
Metabolic activation and cytotoxicity of metaxalone mediated by cytochrome P450 enzymes and sulfotransferases
点击查看 >>
Author：
He Liu, Zixia Hu, Ningning Han, Yi Yang, Guode Zhao, Mengdie Su, Yue Zhang, Weiwei Li, Ying Peng, Jiang Zheng
IF：
5.1000
Publish_to：
CHEMICO-BIOLOGICAL INTERACTIONS
PMID：
37442290
Selenium-Enriched Lactobacillus acidophilus Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice by Regulating Inflammatory Cytokines and Intestinal Microbiota
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Author：
Wu Zeyu, Pan Dan, Jiang Min, Sang Lixuan, Chang Bing
IF：
5.0930
Publish_to：
Frontiers in Medicine
PMID：
34532332
MRI/PAI Dual-modal Imaging-guided Precise Tracking of Bone Marrow-derived Mesenchymal Stem Cells Labeled with Nanoparticles for Treating Liver Cirrhosis
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Author：
Feng-Yong Liu, Ming Shi, Xin Li, Hong-Jun Yuan, Xiao-Mei Tian, Yi-Mao Xia, Min Zhou, Fu-Sheng Wang
IF：
5.0650
Publish_to：
Journal of Clinical and Translational Hepatology
PMID：
36643042
RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice
点击查看 >>
Author：
Li Xiaoxiao, Hua Shuyao, Fang Dai, Fei Xiaoyuan, Tan Zheng, Zheng Fang, Wang Weimin, Fang Min
IF：
5.0570
Publish_to：
CLINICAL AND EXPERIMENTAL MEDICINE
PMID：
36454447
Pseudoginsenoside-F11 promotes functional recovery after transient cerebral ischemia by regulating the microglia/macrophage polarization in rats
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Author：
Ying Hou, Depeng Yang, Xianshi Wang, Huiyang Wang, Haotian Zhang, Pengwei Wang, Yinglu Liu, Xiaoyun Gao, Jingyu Yang, Chunfu Wu
IF：
4.9320
Publish_to：
INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：
34246061
Replacing Hydrolyzed Soybean Meal with Recombinant β-Glucosidase Enhances Resistance to Clostridium perfringens in Broilers Through Immune Modulation
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Author：
Jingxi Huang, Qihang Hou, Ying Yang
IF：
4.9000
Publish_to：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PMID：
39519252
Zishen Yutai Pills Promote Angiogenesis at the Maternal-Fetal Interface in Recurrent Spontaneous Abortion Mice by Regulating miR-187/VEGF Axis
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Author：
Xiaoli Wang, Heng Hu, Xinhui Yu, Chengcheng Liang, Yanquan Han, Hongxia Chen, Jijun Chu
IF：
4.8000
Publish_to：
Drug Design Development and Therapy
PMID：
38370565
Butyrate induces STAT3/HIF-1α/IL-22 signaling via GPCR and HDAC3 inhibition to activate autophagy in head kidney macrophages from turbot (Scophthalmus maximus L.)
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Author：
Jinjin Zhang, Wentao Wang, Shufei Liang, Xueqi zhou, Rokeya Sultana Rekha, Gudmundur H. Gudmundsson, Peter Bergman, Qinghui Ai, Kangsen Mai, Min Wan
IF：
4.7000
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
37977544
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance
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Author：
Wanying Qin, Ting Zhang, Mingxia Ge, Huimin Zhou, Yuhui Xu, Rongfang Mu, Chaoguang Huang, Daowei Liu, Bangrui Huang, Qian Wang, Qinghua Kong, Qingpeng Kong, Fei Li, Wenyong Xiong
IF：
4.6690
Publish_to：
JOURNAL OF ENDOCRINOLOGY
PMID：
35608066
Modulation of Microglia M2 Polarization and Alleviation of Hippocampal Neuron Injury By MiR-106b-5p/RGMa in a Mouse Model of Status Epilepticus
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Author：
Yu Tao, Huo Liang, Lei Jie, Sun Jing‑Jing, Wang Hua
IF：
4.6570
Publish_to：
INFLAMMATION
PMID：
35789312
Involvement and characterization of NLRCs and pyroptosis-related genes in Nile tilapia (Oreochromis niloticus) immune response
点击查看 >>
Author：
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Yu Huang, Jichang Jian, Qingpi Yan
IF：
4.6220
Publish_to：
FISH & SHELLFISH IMMUNOLOGY
PMID：
36150410
MALAT1 expression in granulosa cells in PCOS patients with different phenotypes
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Author：
Li Shumin, Li Yimeng, Yan Xueqi, Zhao Shigang, Yang Ziyi, Wang Yuteng, Gao Xueying, Chen Zi-Jiang
IF：
4.6000
Publish_to：
Scientific Reports
PMID：
38424234
Multiomics Analysis Reveals Molecular Abnormalities in Granulosa Cells of Women With Polycystic Ovary Syndrome
点击查看 >>
Author：
Zhao Rusong, Jiang Yonghui, Zhao Shigang, Zhao Han
IF：
4.5990
Publish_to：
Frontiers in Genetics
PMID：
34084179
ZEB2, interacting with MDM2, contributes to the dysfuntion of brain microvascular endothelial cells and brain injury after intracerebral hemorrhage
点击查看 >>
Author：
Qingbao Guo, Manli Xie, Miao Guo, Feiping Yan, Lihong Li, Rui Liu
IF：
4.5340
Publish_to：
CELL CYCLE
PMID：
34334113
Immunogenicity Analysis of the Recombinant Plasmodium falciparum Surface-Related Antigen in Mice
点击查看 >>
Author：
Jia-Li Yu, Qing-Yang Liu, Bo Yang, Yi-Fan Sun, Ya-Ju Wang, Jian Jiang, Bo Wang, Yang Cheng, Qiu-Bo Wang
IF：
4.5310
Publish_to：
Pathogens
PMID：
35631071
Enhancing immune responses in Japanese flounder (Paralichthys olivaceus) to Keyhole Limpet Hemocyanin by intramuscularly conjugating a new type of chemokine, JfCXCL8_L1b
点击查看 >>
Author：
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
IF：
4.5000
Publish_to：
AQUACULTURE
PMID：
The Contribution of Hepatic Macrophage Heterogeneity during Liver Regeneration after Partial Hepatectomy in Mice
点击查看 >>
Author：
Pengfei Ma, Wenchao Zhao, Chunchen Gao, Zhiwei Liang, Longshuan Zhao, Hongyan Qin, Xiaolin Sun
IF：
4.4930
Publish_to：
Journal of Immunology Research
PMID：
36249420
Inhibition of PAD4-mediated NET formation by cl-amidine prevents diabetes development in nonobese diabetic mice
点击查看 >>
Author：
Yiming Shen, Qi You, Yiling Wu, Jie Wu
IF：
4.4320
Publish_to：
EUROPEAN JOURNAL OF PHARMACOLOGY
PMID：
34767782
Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells
点击查看 >>
Author：
Zhou Jie, Guo Cheng, Wu Hao, Li Bing, Zhou Li-Li, Liang Ai-Bin, Fu Jian-Fei
IF：
4.4300
Publish_to：
BMC CANCER
PMID：
34773997
Role of Nrf2/HO-1 pathway on inhibiting activation of ChTLR15/ChNLRP3 inflammatory pathway stimulated by E. tenella sporozoites
点击查看 >>
Author：
Bingrong Bai, Qiuju Liu, Rui Kong, Zhipeng Jia, Hang Chen, Wenjing Zhi, Biao Wang, Chunli Ma, Dexing Ma
IF：
4.4000
Publish_to：
POULTRY SCIENCE
PMID：
38262340
Luteolin exerts anti-tumour immunity in hepatocellular carcinoma by accelerating CD8+ T lymphocyte infiltration
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Author：
Shijiao Cai, Yidan Gou, Yanyan Chen, Xiaoran Hou, Jing Zhang, Chongwen Bi, Peng Gu, Miao Yang, Hanxu Zhang, Weilong Zhong, Hengjie Yuan
IF：
4.3000
Publish_to：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
PMID：
39267250
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
点击查看 >>
Author：
Yu Shi, Yi-Fang Ping[…]Xiu-Wu Bian
IF：
4.2590
Publish_to：
Nature Communications 8, Article number: 15080 (2017)
PMID：
28569747
HAO2 protects from proximal tubular cells injured in rats with chronic kidney disease by promoting fatty acid metabolic processes
点击查看 >>
Author：
Deyu Zuo, Minghao Luo, Chengxuan Liu, Aimin Yang, Youfeng Shen, Jian Xu, An He, Xunjia Li
IF：
4.2000
Publish_to：
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
PMID：
39002705
Effects of lead exposure on the activation of microglia in mice fed with high-fat diets
点击查看 >>
Author：
Lei Wu, Shuang Li, Shulan Pang, Bo Zhang, Jierui Wang, Bin He, Linyi Lv, Weixuan Wang, Na Zhao, Yanshu Zhang
IF：
4.1190
Publish_to：
ENVIRONMENTAL TOXICOLOGY
PMID：
34156151
In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A
点击查看 >>
Author：
Aixuan Wang, Qiang Zhao, Minglu Liu, Yang Wang, Guode Zhao, Weiwei Li, Ying Peng, Jiang Zheng
IF：
4.1000
Publish_to：
CHEMICAL RESEARCH IN TOXICOLOGY
PMID：
36795936
GCSF deficiency attenuates nonalcoholic fatty liver disease through regulating GCSFR-SOCS3-JAK-STAT3 pathway and immune cells infiltration
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Author：
Yuwei Zhang, Xuefeng Zhou, Peihao Liu, Xueyang Chen, Jie Zhang, Hong Zhang, Sha Li, Yishu Chen, Xin Song, Jinghua Wang, Hang Zeng, Xiaofen Zhang, Chenxi Tang, Chaohui Yu, Youming Li, Chengfu Xu
IF：
4.0520
Publish_to：
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
PMID：
33470903
Ligusticum chuanxiong promotes the angiogenesis of preovulatory follicles (F1–F3) in late-phase laying hens
点击查看 >>
Author：
Hao Chen, Xin Chen, Zhenlei Ping, Lixue Fang, Xiaowen Jiang, Ming Ge, Jun Ma, Wenhui Yu
IF：
4.0140
Publish_to：
POULTRY SCIENCE
PMID：
36621100
MSCs overexpressing GDNF restores brain structure and neurological function in rats with intracerebral hemorrhage
点击查看 >>
Author：
Jiang Xiaoqian, Zhou Ling, Sun Zihuan, Xie Bingqing, Lin Heng, Gao Xiaoqing, Deng Li, Yang Chaoxian
IF：
4.0000
Publish_to：
Molecular Biomedicine
PMID：
38008847
Metabolic Activation of Perampanel Mediated by CYP1A2
点击查看 >>
Author：
Zifang Ding, Xu Wang, Ning Zhang, Chen Sun, Guode Zhao, Ying Peng, Jiang Zheng
IF：
3.9730
Publish_to：
CHEMICAL RESEARCH IN TOXICOLOGY
PMID：
35200000
The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesis
点击查看 >>
Author：
Yue Zhao, Haoran Liu, Yang Yang, Wenqian Huang, Lan Chao
IF：
3.9230
Publish_to：
REPRODUCTION
PMID：
35312628
Role of PERK-Mediated Endoplasmic Reticulum Stress in Ferroptosis Caused by Hexavalent Chromium in Chicken Hepatocytes
点击查看 >>
Author：
Cui Yukun, Zhang Pu, Song Kaimin, Qi Changxi, Liu Yongxia, Liu Jianzhu
IF：
3.9000
Publish_to：
BIOLOGICAL TRACE ELEMENT RESEARCH
PMID：
38183555
Cholesterol metabolism is decreased in patients with diminished ovarian reserve
点击查看 >>
Author：
Xiulan Yang, Zhongying Zhao, Qigang Fan, Hongli Li, Lihui Zhao, Chang Liu, Xiaolei Liang
IF：
3.8280
Publish_to：
REPRODUCTIVE BIOMEDICINE ONLINE
PMID：
34801402
Prediction of the mechanisms of action of Qutan Huoxue decoction in non-alcoholic steatohepatitis (NASH): a network pharmacology study and experimental validation
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Author：
Xia Wu, Yurong Zhang, Ding Zheng, Yue Yin, Mengyun Peng, Jing Wang, Xiaoning Zhu
IF：
3.8000
Publish_to：
PHARMACEUTICAL BIOLOGY
PMID：
36908041
miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells
点击查看 >>
Author：
Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Manchun Su, Huibin Shi, Xinming Duan, Youji Ma
IF：
3.7520
Publish_to：
PLoS One
PMID：
36137140
Metabolic Activation and Cytotoxicity of Labetalol Hydrochloride Mediated by Sulfotransferases
点击查看 >>
Author：
Lan Yang, Lihua Xin, Junzu Shi, Wei Li, Min Tian, Zixia Hu, Ying Peng, Jiang Zheng
IF：
3.7390
Publish_to：
CHEMICAL RESEARCH IN TOXICOLOGY
PMID：
33872499
Construction and immune efficacy of recombinant Lactobacillus casei expressing OmpAI of Aeromonas veronii C5–I as molecular adjuvant
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Author：
Ze Lin-Zhao, Bin Tong-Yang, Yang Yi-Xuan, Song Ning-Guo, Dong Xing-Zhang, Sheng Nan-Ji, Bing Lv, Yuan Huan-Kang, Xiao Feng-Shan, Qiu Mei-Shi, Wu Wen-Sun, Ai Dong-Qian
IF：
3.7380
Publish_to：
MICROBIAL PATHOGENESIS
PMID：
33892129
Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells
点击查看 >>
Author：
Renye Que, Mengxing Cao, Yancheng Dai, Yi Zhou, Yirong Chen, Liubing Lin
IF：
3.7300
Publish_to：
Biochemistry and Cell Biology
PMID：
35785548
Identification of hub genes and biological mechanisms underlying the pathogenesis of asthenozoospermia and chronic epididymitis
点击查看 >>
Author：
Yinwei Chen, Taotao Sun, Longjie Gu, Song Ouyang, Kang Liu, Penghui Yuan, Chang Liu
IF：
3.7000
Publish_to：
Frontiers in Genetics
PMID：
37152990
PGAM1 regulates the glycolytic metabolism of SCs in tibetan sheep and its influence on the development of SCs
点击查看 >>
Author：
Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Xia Wang, Youji Ma
IF：
3.6880
Publish_to：
GENE
PMID：
34418471
Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma
点击查看 >>
Author：
Weili Xu, Suolin Li, Meng Li, Xiaofeng Yang, Shaojian Xie, Lin Lin, Guixin Li, Hui Zhou
IF：
3.6850
Publish_to：
IMMUNOLOGY LETTERS
PMID：
34600949
Functional differences in the products of two TRAF3 genes in antiviral responses in the Chinese giant salamander, Andrias davidianus
点击查看 >>
Author：
Ya-Ping Xu, Yi-Lian Zhou, Yi Xiao, Wen-Bin Gu, Bo Li, Yuan-Xin Cheng, Bing-Wu Li, Da-Yong Chen, Xiao-Feng Zhao, Wei-Ren Dong, Miao-An Shu
IF：
3.6360
Publish_to：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
PMID：
33460679
The involvement of hypoxia inducible factor-1α on the proportion of three types of haemocytes in Chinese mitten crab under hypoxia stress
点击查看 >>
Author：
Fengchi Wang, Zhichao Yang, Jiaming Li, Yuhan Ma, Yuhan Tu, Xiaorui Zeng, Qingyao Wang, Yusheng Jiang, Shu Huang, Qilin Yi
IF：
3.6050
Publish_to：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
PMID：
36511346
LRRC52 is likely a functional component of human KSper
点击查看 >>
Author：
Zhang Jiali, Zheng Liping, Chen Ying, Luo Tao, Zeng Xuhui, Kang Hang
IF：
3.6000
Publish_to：
BIOLOGY OF REPRODUCTION
PMID：
38267364
Early Growth Response Protein 1 Knockdown Alleviates the Cerebral Injury in Rats with Intracerebral Hemorrhage via STAT3/NF-κB Pathway by Reducing RXRα Acetylation Level
点击查看 >>
Author：
Lijuan Xie, Yingying Wang, Zhuo Chen
IF：
3.5900
Publish_to：
NEUROSCIENCE
PMID：
33600884
LDLR heterozygous deletion reduces hamster testicular cholesterol toxicity via AMPK/Sirt1/PGC-1α pathway
点击查看 >>
Author：
Yun Bai, Naiheng Hei, Mingming Gao, Xiaohui Dong, Mingzhao Li, Shaohao Jiang, Lianshan Zhang
IF：
3.5000
Publish_to：
TOXICOLOGY LETTERS
PMID：
37459939
ELF4 is critical to zygotic gene activation and epigenetic reprogramming during early embryonic development in pigs
点击查看 >>
Author：
Lijing Shi, Yanhui Zhai, Yuanshen Zhao, Xiangjie Kong, Daoyu Zhang, Hao Yu, Ziyi Li
IF：
3.4710
Publish_to：
Frontiers in Veterinary Science
PMID：
35928113
Construction of a Humanized PBMC-PDX Model to Study the Efficacy of a Bacterial Marker in Lung Cancer Immunotherapy
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Author：
Chengwei Wu, Xinning Wang, Haitao Shang, Hong Wei
IF：
3.4640
Publish_to：
DISEASE MARKERS
PMID：
36072895
Panax notoginseng saponins promote endothelial progenitor cell angiogenesis via the Wnt/β-catenin pathway
点击查看 >>
Author：
Zhu Peiqi, Jiang Weidong, He Shixi, Zhang Tao, Liao Fengchun, Liu Di, An Xiaoning, Huang Xuanping, Zhou Nuo
IF：
3.4000
Publish_to：
BMC Complementary Medicine and Therapies
PMID：
33557814
Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia
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Author：
Ting Xue, Xiaodan Wang, Ying Hu, Ying Cheng, Han Li, Yuan Shi, Lijun Wang, Dongmin Yin, Donghong Cui
IF：
3.3330
Publish_to：
Brain Sciences
PMID：
36291328
HSP110 aggravates ischemia-reperfusion injury after liver transplantation by promoting NF-κB pathway
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Author：
Qing-Zhi Hu, Zhen-Rui Cao, Wei-Xiong Zheng, Min-Jie Zhao, Jun-Hua Gong, Cong Chen, Zhong-Jun Wu, Rui Tao
IF：
3.3000
Publish_to：
Hepatobiliary & Pancreatic Diseases International
PMID：
37648554
Effects of compound probiotics and aflatoxin-degradation enzyme on alleviating aflatoxin-induced cytotoxicity in chicken embryo primary intestinal epithelium, liver and kidney cells
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Author：
Guo Hong-Wei, Chang Juan, Wang Ping, Yin Qing-Qiang, Liu Chao-Qi, Xu Xiao-Xiang, Dang Xiao-Wei, Hu Xiao-Fei, Wang Quan-Liang
IF：
3.2980
Publish_to：
AMB Express
PMID：
33646441
Silenced-C5ar1 improved multiple organ injury in sepsis rats via inhibiting neutrophil extracellular trap
点击查看 >>
Author：
Shen Bin, Shen Qikai, Zeng Qingqiu, Zhang Lingyan, Li Xiaofeng
IF：
3.2000
Publish_to：
JOURNAL OF MOLECULAR HISTOLOGY
PMID：
38165570
Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection
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Author：
Xu Hua, Kang Juan, Zhong Shan, Chen Min, Hu Peng, Ren Hong, Zhou Zhi, Lei Yu
IF：
3.0000
Publish_to：
BMC IMMUNOLOGY
PMID：
37752416
Carboxypeptidase E protein regulates porcine sperm Ca2+ influx to affect capacitation and fertilization
点击查看 >>
Author：
Fanwen Zeng, Xuedan Zhu, Chengde Li, Beibei Han, Li Meng, Li Li, Hengxi Wei, Shouquan Zhang
IF：
2.9230
Publish_to：
THERIOGENOLOGY
PMID：
36041383
Echinococcus multilocularis serpin regulates macrophage polarization and reduces gut dysbiosis in colitis
点击查看 >>
Author：
Xiaolu Li, Yihui Liu, Yang Zou, Jiayun Zhang, Yugui Wang, Yingying Ding, Zhiqi Shi, Xiaola Guo, Shaohua Zhang, Hong Yin, Aijiang Guo, Shuai Wang
IF：
2.9000
Publish_to：
INFECTION AND IMMUNITY
PMID：
39037247
Identification and characterization of Eimeria tenella EtTrx1 protein
点击查看 >>
Author：
Huihui Li, Lingyu Sun, Yingying Jiang, Bingxiang Wang, Zhiyuan Wu, Jinkun Sun, Xiao Zhang, Hongmei Li, Xiaomin Zhao
IF：
2.8210
Publish_to：
VETERINARY PARASITOLOGY
PMID：
35994916
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy-to-perform approaches
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Author：
Yalan Lu, Yunlin Han, Li Zhou, Guiying Shi, Lin Bai, Kewei Wang, Chuan Qin
IF：
2.7920
Publish_to：
FEBS Open Bio
PMID：
36153697
Effects and Action Mechanism of Huoxue Tongluo Formula on the Formation of Neutrophil Extracellular Traps
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Author：
Xiaoli Zhou, Weixiang Liao, Wei Peng, Tingting Xie, Qianlu Yin, Yuhang Zheng
IF：
2.6500
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
36034958
Panax notoginseng Saponin Promotes Bone Regeneration in Distraction Osteogenesis via the TGF-β1 Signaling Pathway
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Author：
Di Liu, Zhenchen Zhao, Weidong Jiang, Peiqi Zhu, Xiaoning An, Yu Xie, Xuanping Huang, Nuo Zhou
IF：
2.6300
Publish_to：
Evidence-based Complementary and Alternative Medicine
PMID：
34721625
Regulatory T Cells Secrete IL10 to Suppress Neuroinflammation in Early Stage after Subarachnoid Hemorrhage
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Author：
Jingyi Zhou, Fan Yang, Huaming Li, Penglei Xu, Zefeng Wang, Fangjie Shao, Anwen Shao, Jianmin Zhang
IF：
2.6000
Publish_to：
Medicina-Lithuania
PMID：
37512128
Protective effects of monoammonium glycyrrhizinate on fatty deposit degeneration induced in primary calf hepatocytes by sodium oleate administration in vitro
点击查看 >>
Author：
Cai Zhang, Sudan Meng, Qi Shao, Xueying Wang, Chenxu Li, Wenbin Chen, Yuanxiao Li, Shucheng Huang, Yanbo Ma
IF：
2.5540
Publish_to：
RESEARCH IN VETERINARY SCIENCE
PMID：
35868152
Upregulation of CD3ζ and L-selectin in antigen-specific cytotoxic T lymphocytes by eliminating myeloid-derived suppressor cells with doxorubicin to improve killing efficacy of neuroblastoma cells in vitro
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Author：
Weili Xu, Suolin Li, Meng Li, Hui Zhou, Xiaofeng Yang
IF：
2.3520
Publish_to：
JOURNAL OF CLINICAL LABORATORY ANALYSIS
PMID：
34861064
P2RX1 in neutrophils mediates JAK/STAT signaling pathway to regulate malignant phenotype of gastric Cancer cells
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Author：
Zhang Yan, Zhang Fenglin, Liu Zhi, Li Min, Wu Ge, Li Hui
IF：
2.3000
Publish_to：
MOLECULAR GENETICS AND GENOMICS
PMID：
39985719
A novel Ush transcription factor involving in hematopoiesis of Eriocheir sinensis
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Author：
Liyan Wang, Fang Liu, Guangcheng Zhang, Hui Su, Jinsheng Sun
IF：
2.2310
Publish_to：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
PMID：
34915123
In silico approach uncovers the shared genetic landscape of type 2 diabetes mellitus and asthenozoospermia
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Author：
Yinwei Chen, Taotao Sun, Chang Liu, Longjie Gu, Penghui Yuan
IF：
2.1000
Publish_to：
Systems Biology in Reproductive Medicine
PMID：
39292564
Downregulation of miR-23a-3p improves cognitive function in rats after subarachnoid hemorrhage by targeting VCAN
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Author：
Xue Cheng, Wang Rong, Jia Yu
IF：
2.0700
Publish_to：
Medical Molecular Morphology
PMID：
35137264
In vitro and in vivo metabolic profiling of PD105, a PI3Kδ inhibitor, using UHPLC-Q-Exactive plus-MS
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Author：
Panhong Wei, Minghai Tang, Ziyan MA, Jiajia Zhao, Rui Wu, Li Wan
IF：
1.8000
Publish_to：
XENOBIOTICA
PMID：
36877930
Analysis of bacterial spectrum, activin A, and CD64 in chronic obstructive pulmonary disease patients complicated with pulmonary infections
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Author：
Zhao-Yang Fei, Jiang Wang, Jie Liang, Xue Zhou, Min Guo
IF：
1.5340
Publish_to：
World Journal of Clinical Cases
PMID：
35434072
CD69 predicts prognosis through immune cell infiltration and decitabine treatment response in acute myeloid leukemia
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Author：
Jie Zhou, Hao Wu, Bing Li, Lixin Lv, Shunli Zhu, Aibin Liang, Jianfei Fu
IF：
1.5000
Publish_to：
Translational Cancer Research
PMID：
40104698
Therapeutic effects of Hedyotis diffusa Willd in a COPD mouse model challenged with LPS and smoke
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Author：
Renping Liu Peihong Wang Caiqing Wu Juan Chen
IF：
1.4100
Publish_to：
Experimental
and Therapeutic
Medicine
PMID：
29545859
技术问答
（21）
注意：
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索莱宝这个percoll分离液和GE使用方法一样的吗？还是哪里不同，可以根据文献按GE的percoll方法用吗?2023-12-19 10:56:27
您好，percoll分离细胞，是依据细胞不连续密度梯度差原理进行处理。可参考文献及资料获取想要分离细胞的相关分离密度，具体配置不同密度梯度时，请参考该试剂使用说明书。如有疑问，可电话咨询4009686088转2。
80%percoll怎么配?2023-09-20 15:54:03
您好，先用9份Percoll分离液与1份8.5％ NaCl混合达到生理性渗透压，然后用生理溶液(0.85％ NaCl)稀释到所需浓度。
请问一定要用8.5%和0.85%的NaCl吗，可以用10x和1xPBS替代NaCl稀释吗?2023-09-11 15:49:32
您好，可以用PBS配制，但需要的浓度是1.5M和0.15M。
请问可以从骨髓中分离巨核细胞吗?2023-08-14 10:38:21
您好，本试剂可根据细胞密度不同达到粗分离效果，具体需要看您需分离的细胞密度是多少。
请问是无菌的吗？如果不是，121摄氏度，20分钟高温灭菌可以吗?2023-08-07 17:25:15
您好，试剂本身是无菌的，可以使用120°C，30 min高压进行灭菌处理，需注意Percoll灭菌前不能加入盐溶液，否则会导致凝胶化，也不能先加入蔗糖，高压会导致蔗糖焦化。