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JC-10 线粒体膜电位荧光探针
英文名称:JC-10 Mitochondrial Membrane Potential Fluorescent Probe
分子量:~600
储存条件:-20℃干燥避光保存，保质期1年。
产品简介
| 中文名称 | JC-10 线粒体膜电位荧光探针 |
| 英文名称 | JC-10 Mitochondrial Membrane Potential Fluorescent Probe |
| 别名 | 线粒体膜电位荧光探针 |
| 分子量 | ~600 |
| 外观(性状) | Ex (nm)510 Em (nm)525 溶剂DMSO |
| 储存条件 | -20℃干燥避光保存，保质期1年。 |
| 规格 | 1mg 5mg |
| 单位 | 瓶 |
JC-10 是一种广泛用于检测线粒体膜电位△Ψm 的理想荧光探针。可以检测细胞、组织或纯化的线粒体膜电位。在线粒体膜电位较高时，JC-10 聚集在线粒体的基质中，形成聚合物，可以产生红色荧光；在线粒体膜电位较低时，JC-10 不能聚集在线粒体的基质中，此时 JC-10 为单体，可以产生绿色荧光。这样就可以非常方便地通过荧光颜色的转变来检测线粒体膜电位的变化。常用红绿荧光的相对比例来衡量线粒体去极化的比例。
线粒体膜电位的下降是细胞凋亡早期的一个标志性事件。通过 JC-10 从红色荧光到绿色荧光的转变可以很容易地检测到细胞膜电位的下降，同时也可以用JC-10 从红色荧光到绿色荧光的转变作为细胞凋亡早期的一个检测指标。JC-10 单体的最大激发波长为 515nm ，最大发射波长为529nm ；JC-10 聚合物的最大激发波长为585nm ，最大发射波长为590nm 。实际观察时，使用常规的观察红色荧光和绿色荧光的设置即可。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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技术问答
（1）
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
京公网安备 11011202000391号
你好，我想问一下这款产品配制的储存浓度和工作浓度建议是多少？能否用于做流式检测和免疫荧光检测？能否用于甲醛或甲醇的固定?2023-05-11 15:55:47
您好，一般用DMSO溶解，储存液参考浓度5mg/ml，工作浓度需要自行查找文献确定。可以用于流式和荧光检测。