中文
英语
青霉素G钠盐
CAS:No.69-57-8
分子式:C16H17N2O4SNa
分子量:356.37
储存条件:RT，有效期2年
英文名称:Penicillin G Sodium salt
产品简介
| 别名 | 苄基青霉素钠盐；Benzylpenicillin sodium salt |
| 英文名称 | Penicillin G Sodium salt |
| CAS | No.69-57-8 |
| 分子式 | C16H17N2O4SNa |
| 分子量 | 356.37 |
| 储存条件 | RT，有效期2年 |
| 外观(性状) |
白色粉末
|
| 酶活/效价 | Potency (Anhydrous) (U/mg) 1550 |
| 溶解性 | 100mg/ml in Water |
| 危险代码 | R：36/37/38; 42/43 S：36/37/39 |
| 规格 | 1g 5g 25g |
| 单位 | 瓶 |
原理：青霉素类抗生素是β-内酰胺类中一大类抗生素的总称。其抗菌谱较窄，主要对革兰氏阳性菌有效。青霉素具有抗菌作用强、疗效高及毒性低等优点，故至今仍被广泛应用。青霉素是有机酸，能和多种金属结合成盐，常用其钠盐或钾盐。青霉素可用化学裂解法除去酰基而生成6-APA（6-氨基青霉烷酸），是各种半合成青霉素的中间体。
说明：青霉素主要对革兰氏阳性菌有效，作用于细菌的细胞壁，对人类的毒性较小。推荐工作浓度为100 U/ml。
用途：生化研究；培养基的配制；抗生素。
特性：水分(%)：≤1.5 pH (6%,水) 25℃：5.0-7.5
溶解性：溶于水，参考浓度100mg/ml，过滤除菌，于-20 ℃长期保存，2-8℃保存一周，37℃保存3天。
配置：用于细胞培养，在细胞培养液中推荐的青霉素的工作浓度为100U/ml。用去离子水或PBS溶解青霉素G钠盐，0.22μm滤器过滤除菌，浓缩液-20℃分装保存。
在培养基中能预防细菌污染。常用的是青链霉素，俗称“双抗溶液”。青霉素主要是对革兰氏阳性菌有效，链霉素主要对革兰氏阴性菌有效。加入这两种抗生素可预防绝大多数细菌污染。双抗对细菌有用，加入培养基一周有效，之后失活。如果培养条件好，可以不加。建议药物实验不加双抗，因为它对细胞形态、代谢还是有一点影响。
注意事项:
(1)用于细胞实验，溶解后，须用一次性针头滤器过滤除菌。
(2)为了您的安全和健康，请穿实验服并戴一次性手套操作。
备注：产品信息可能会有优化升级。请以实际标签信息为准。
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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Junxu Yang, Zizhu Hu, Xiao Ru, Mingwei He, Ziwei Hu, Xiong Qin, Shihui Xiao, Dachang Liu, Hanji Huang, Qingjun Wei
IF：
2.6000
Publish_to：
GENE
PMID：
39761802
c-Myc, RMRP, and miR-34a-5p form a positive-feedback loop to regulate cell proliferation and apoptosis in multiple myeloma
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Author：
Xichun Xiao,Yueli Gu,Genjie Wang,Shuxia Chen
IF：
2.5960
Publish_to：
International journal of biological Macromolecules
PMID：
30389523
Carfilzomib inhibits the progression of hepatocellular cancer by upregulating GADD45α expression
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Author：
Mingxun Chen, Xu Chen, Yifang Shui, Chunyong Ji, Wenzhi Guo
IF：
2.5000
Publish_to：
Oncology Letters
PMID：
40070787
Non-targeted Metabolomics Reveals the Potential Role of MFSD8 in Metabolism in Human Endothelial Cells
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Author：
Xiang Qin, Chen Yongjun, Cheng Xu, Fang Xinxiang, Liu Yuxiang, Huang Yujie, He Binsheng, Tang Liang, Li Jianming
IF：
2.4000
Publish_to：
MOLECULAR BIOTECHNOLOGY
PMID：
39992484
Enhancing bile tolerance of Lactobacilli is involved in the hypolipidemic effects of liraglutide
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Author：
Wang Chang, Hu Hai-Jie, Dong Qing-Qing, Huang Rui, Zhao Wei, Song Ya-Jian, Li Zhong-Yuan, Wang Nan, Zhang Tong-Cun, Luo Xue-Gang
IF：
2.0430
Publish_to：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
PMID：
33784390
Effects of Chlorogenic Acid on In Vitro Maturation and Vitrification Cryopreservation of Sheep Oocytes
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Author：
Hong Tao, Yukun Zhao, Qiang Zhang, Xu Li, Guangdong Hu, Yanping Wang, Weibin Zeng
IF：
2.0000
Publish_to：
Veterinary Sciences
PMID：
39852937
Adipose-Derived Mesenchymal Stem Cells Transplantation Alleviates Renal Injury in Streptozotocin-Induced Diabetic Nephropathy
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Author：
Weimin Ni, Yan Fang, Ling Xie, Xue Liu, Wei Shan,
IF：
1.9530
Publish_to：
Journal of Histochemistry & Cytochemistry
PMID：
26215800
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